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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: ELF1,2,4.p2

Z-value: 0.671

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_+_36365640	1.309		SH3BP1	SH3-domain binding protein 1
chr5_+_61910318	1.197	NM_181506	LRRC70	leucine rich repeat containing 70
chr9_-_34116549	1.189		DCAF12	DDB1 and CUL4 associated factor 12
chr20_-_2589476	1.148		IDH3B	isocitrate dehydrogenase 3 (NAD+) beta
chr9_-_34116688	1.123		DCAF12	DDB1 and CUL4 associated factor 12
chr10_-_116434364	1.086	NM_001003407 NM_001003408	ABLIM1	actin binding LIM protein 1
chr13_+_110653407	1.037		ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr5_+_153805761	1.003		SAP30L	SAP30-like
chr9_-_34116703	0.947	NM_015397	DCAF12	DDB1 and CUL4 associated factor 12
chr2_-_230494956	0.919		TRIP12	thyroid hormone receptor interactor 12
chr18_+_54489658	0.876		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr2_-_230494862	0.876	NM_004238	TRIP12	thyroid hormone receptor interactor 12
chr9_-_88159143	0.863	NM_001185059 NM_001185074 NM_024617	ZCCHC6	zinc finger, CCHC domain containing 6
chr1_-_111308017	0.861	NM_001006945 NM_018372	C1orf103	chromosome 1 open reading frame 103
chr18_+_54489597	0.855	NM_006785 NM_173844	MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr21_-_32906729	0.844	NM_021254	C21orf59	chromosome 21 open reading frame 59
chr1_+_153445113	0.826	NM_002455 NM_198883	MTX1	metaxin 1
chr10_-_89567863	0.821	NM_032810	ATAD1	ATPase family, AAA domain containing 1
chr4_-_48477021	0.802		FRYL	FRY-like
chr8_-_57149588	0.800	NM_001023 NM_001146227	RPS20	ribosomal protein S20
chr15_-_72540543	0.793	NM_032907 NM_201265	UBL7	ubiquitin-like 7 (bone marrow stromal cell-derived)
chr18_+_54489763	0.791		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr15_-_72540518	0.788		UBL7	ubiquitin-like 7 (bone marrow stromal cell-derived)
chr2_-_9613191	0.782		ADAM17	ADAM metallopeptidase domain 17
chr2_-_201461945	0.781	NM_032472 NM_130906	PPIL3	peptidylprolyl isomerase (cyclophilin)-like 3
chr6_-_11490487	0.768	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr10_+_112669349	0.759		SHOC2	soc-2 suppressor of clear homolog (C. elegans)
chr17_-_12861973	0.740		ELAC2	elaC homolog 2 (E. coli)
chr2_-_9481035	0.737		ITGB1BP1	integrin beta 1 binding protein 1
chr4_+_152417774	0.734	NM_183375	PRSS48	protease, serine, 48
chr9_-_21325239	0.733	NM_018847	KLHL9	kelch-like 9 (Drosophila)
chr8_+_125620523	0.732	NM_005005	NDUFB9	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
chr9_-_37775052	0.729		EXOSC3	exosome component 3
chr10_-_116434102	0.712		ABLIM1	actin binding LIM protein 1
chr4_-_140224914	0.707	NM_006874	ELF2	E74-like factor 2 (ets domain transcription factor)
chr14_-_54025464	0.702	NM_004124	GMFB	glia maturation factor, beta
chr10_+_127398073	0.688	NM_015608	C10orf137	chromosome 10 open reading frame 137
chr3_+_185515543	0.686	NM_182917	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr14_-_23106779	0.679		AP1G2	adaptor-related protein complex 1, gamma 2 subunit
chr2_-_240724373	0.678	NM_001163424 NM_138336	MYEOV2	myeloma overexpressed 2
chr2_-_9481038	0.668	NM_004763 NM_022334	ITGB1BP1	integrin beta 1 binding protein 1
chr15_-_50758100	0.667	NM_019600	KIAA1370	KIAA1370
chr9_-_3515973	0.652	NM_002919 NM_134428	RFX3	regulatory factor X, 3 (influences HLA class II expression)
chr12_-_52939636	0.641	NM_001127321	CBX5	chromobox homolog 5
chr14_+_22845851	0.639	NM_004050	BCL2L2-PABPN1 BCL2L2	BCL2L2-PABPN1 read-through transcript BCL2-like 2
chr20_+_34635362	0.633	NM_021809	TGIF2	TGFB-induced factor homeobox 2
chrX_+_119268518	0.632	NM_006777 NM_001184742	ZBTB33	zinc finger and BTB domain containing 33
chr10_+_1092799	0.628		WDR37	WD repeat domain 37
chr8_+_38153453	0.625		BAG4	BCL2-associated athanogene 4
chr2_-_9613278	0.623		ADAM17	ADAM metallopeptidase domain 17
chr5_+_179934143	0.622		CNOT6	CCR4-NOT transcription complex, subunit 6
chr20_-_33198721	0.617	NM_001145025 NM_018217	EDEM2	ER degradation enhancer, mannosidase alpha-like 2
chr2_-_74521061	0.611	NM_001015056 NM_033046	RTKN	rhotekin
chr6_-_56824672	0.604		DST	dystonin
chr6_-_166676016	0.603		SFT2D1	SFT2 domain containing 1
chr22_+_36365664	0.601		SH3BP1	SH3-domain binding protein 1
chr10_+_12278185	0.601		CDC123	cell division cycle 123 homolog (S. cerevisiae)
chr5_+_69732561	0.596		SMA4	glucuronidase, beta pseudogene
chr5_+_67547357	0.589		PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_+_168030798	0.581		C1orf112	chromosome 1 open reading frame 112
chrX_+_24621984	0.578	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chrX_+_119268713	0.575
chr19_-_16103996	0.575
chr9_+_4669557	0.573	NM_017913	CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1
chr9_-_35738875	0.569		GBA2	glucosidase, beta (bile acid) 2
chr1_-_154257320	0.563		SSR2	signal sequence receptor, beta (translocon-associated protein beta)
chr11_+_7574992	0.561		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_85742028	0.559		SFTPB	surfactant protein B
chr18_+_70416090	0.558		ZNF407	zinc finger protein 407
chr13_+_30089829	0.556	NM_005800	USPL1	ubiquitin specific peptidase like 1
chr16_-_87877197	0.556		ANKRD11	ankyrin repeat domain 11
chrX_+_102518764	0.553	NM_014380	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr22_+_36365629	0.552	NM_018957	SH3BP1	SH3-domain binding protein 1
chr19_+_18529571	0.550	NM_001171948 NM_001171949 NM_024069	C19orf50	chromosome 19 open reading frame 50
chr4_+_25524903	0.550	NM_001145432	C4orf52	chromosome 4 open reading frame 52
chr14_-_68689623	0.549	NM_003861	DCAF5	DDB1 and CUL4 associated factor 5
chr1_+_158579796	0.546		NCSTN	nicastrin
chr9_-_35739144	0.544		GBA2	glucosidase, beta (bile acid) 2
chr5_+_157090900	0.544	NM_017872	THG1L	tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr2_-_9613336	0.543	NM_003183	ADAM17	ADAM metallopeptidase domain 17
chr10_+_114196698	0.539	NM_145206	VTI1A	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
chr1_-_32460526	0.539		TMEM234	transmembrane protein 234
chr22_+_36412277	0.538	NM_024313	NOL12	nucleolar protein 12
chr12_-_368689	0.537	NM_001042603	KDM5A	lysine (K)-specific demethylase 5A
chr6_+_43592812	0.537		POLR1C	polymerase (RNA) I polypeptide C, 30kDa
chr3_-_113763449	0.536		ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr9_+_131856007	0.536		GPR107	G protein-coupled receptor 107
chr1_-_32888677	0.531	NM_178547	ZBTB8OS	zinc finger and BTB domain containing 8 opposite strand
chr14_-_76913148	0.531	NM_213601	TMED8	transmembrane emp24 protein transport domain containing 8
chr9_+_130354490	0.531	NM_001130438 NM_001195532 NM_003127	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr3_+_14668283	0.530		C3orf19	chromosome 3 open reading frame 19
chr7_+_102775309	0.529	NM_002803	PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr19_+_40931285	0.529	NM_019104	LIN37	lin-37 homolog (C. elegans)
chr1_-_35795525	0.527		KIAA0319L	KIAA0319-like
chr14_+_38720085	0.526		PNN	pinin, desmosome associated protein
chr9_+_35739321	0.526		RGP1	RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr12_-_368517	0.526		KDM5A	lysine (K)-specific demethylase 5A
chr2_+_32435800	0.524		BIRC6	baculoviral IAP repeat containing 6
chr6_-_36950520	0.524		PPIL1	peptidylprolyl isomerase (cyclophilin)-like 1
chr17_-_12862032	0.520		ELAC2	elaC homolog 2 (E. coli)
chr9_-_7789609	0.520	NM_033428	C9orf123	chromosome 9 open reading frame 123
chr12_+_51686328	0.519	NM_001417	EIF4B	eukaryotic translation initiation factor 4B
chr9_-_123003963	0.517		RAB14	RAB14, member RAS oncogene family
chr6_+_144206202	0.517		LTV1	LTV1 homolog (S. cerevisiae)
chr16_+_2672527	0.516		KCTD5	potassium channel tetramerisation domain containing 5
chr6_-_42293577	0.516		MRPS10	mitochondrial ribosomal protein S10
chr15_+_63948823	0.514	NM_004663	RAB11A	RAB11A, member RAS oncogene family
chr7_-_100009205	0.514	NM_001168682	SAP25	sin3A-binding protein 25
chr12_+_6703410	0.514	NM_001164094 NM_016319 NM_001164095	COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr6_-_76050837	0.511
chr17_+_39619826	0.510	NM_001076674 NM_024107	TMUB2	transmembrane and ubiquitin-like domain containing 2
chr16_+_2672476	0.503	NM_018992	KCTD5	potassium channel tetramerisation domain containing 5
chr6_-_76051159	0.503		TMEM30A	transmembrane protein 30A
chr11_+_73559900	0.501		PPME1	protein phosphatase methylesterase 1
chr9_-_35739209	0.501	NM_020944	GBA2	glucosidase, beta (bile acid) 2
chr19_-_58052664	0.500	NM_001008801 NM_199132	ZNF468	zinc finger protein 468
chr9_-_123003982	0.499		RAB14	RAB14, member RAS oncogene family
chr10_-_43212681	0.496		HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr12_+_6703549	0.496		COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr13_+_110604039	0.494	NM_003899	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr9_-_3515721	0.493		RFX3	regulatory factor X, 3 (influences HLA class II expression)
chr2_-_207738858	0.493	NM_003709	KLF7	Kruppel-like factor 7 (ubiquitous)
chr9_-_135213149	0.493		SURF1	surfeit 1
chr17_+_64019748	0.492		PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr3_+_52296893	0.492		GLYCTK	glycerate kinase
chr10_+_114033403	0.490	NM_058222	TECTB	tectorin beta
chr8_-_103735194	0.489	NM_001032282	KLF10	Kruppel-like factor 10
chr6_-_42293575	0.489		MRPS10	mitochondrial ribosomal protein S10
chr7_+_141124710	0.488	NM_016944	TAS2R4	taste receptor, type 2, member 4
chr7_+_99451110	0.485	NM_003439	ZKSCAN1	zinc finger with KRAB and SCAN domains 1
chr11_+_70841864	0.485	NM_018161	NADSYN1	NAD synthetase 1
chr1_+_38033666	0.484	NM_152496	MANEAL	mannosidase, endo-alpha-like
chr7_-_143622233	0.483		ARHGEF35	Rho guanine nucleotide exchange factor (GEF) 35
chr20_-_42584100	0.482	NM_006811 NM_198941	SERINC3	serine incorporator 3
chr12_+_6703525	0.481		COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr2_-_241149132	0.480		ANKMY1	ankyrin repeat and MYND domain containing 1
chr22_-_34566276	0.480		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_7855400	0.479	NM_004650	PNPLA4	patatin-like phospholipase domain containing 4
chr10_-_112668679	0.478	NM_001195306	BBIP1	BBSome interacting protein 1
chr1_-_33055431	0.477		YARS	tyrosyl-tRNA synthetase
chr10_+_1092741	0.476	NM_014023	WDR37	WD repeat domain 37
chr2_-_54051290	0.476	NM_014614	PSME4	proteasome (prosome, macropain) activator subunit 4
chr20_-_5879036	0.476	NM_015939	TRMT6	tRNA methyltransferase 6 homolog (S. cerevisiae)
chr4_+_39874921	0.475	NM_004310	RHOH	ras homolog gene family, member H
chr14_+_74418345	0.474	NM_001933	DLST	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr20_+_48560327	0.474		PTPN1	protein tyrosine phosphatase, non-receptor type 1
chr4_+_164635263	0.473		C4orf43	chromosome 4 open reading frame 43
chr2_-_70374349	0.472	NM_003096	SNRPG	small nuclear ribonucleoprotein polypeptide G
chr1_+_229181417	0.471	NM_022786	ARV1	ARV1 homolog (S. cerevisiae)
chr14_-_74713086	0.469		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr2_+_198026470	0.467	NM_025147	COQ10B	coenzyme Q10 homolog B (S. cerevisiae)
chr1_-_148249152	0.467	NM_020205	OTUD7B	OTU domain containing 7B
chr3_+_151747266	0.463		EIF2A	eukaryotic translation initiation factor 2A, 65kDa
chr17_-_6484749	0.463		KIAA0753	KIAA0753
chr14_-_68689284	0.460		DCAF5	DDB1 and CUL4 associated factor 5
chr3_+_123882355	0.460	NM_017554	PARP14	poly (ADP-ribose) polymerase family, member 14
chr17_-_41658493	0.459	NM_001193465	KIAA1267	KIAA1267
chrX_-_19815586	0.459	NM_031892	SH3KBP1	SH3-domain kinase binding protein 1
chr22_-_34566210	0.459		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_+_118273887	0.457	NM_006784	WDR3	WD repeat domain 3
chr17_+_70520339	0.456	NM_001545	ICT1	immature colon carcinoma transcript 1
chr9_-_35093089	0.456		STOML2	stomatin (EPB72)-like 2
chr11_-_62170655	0.455		GANAB	glucosidase, alpha; neutral AB
chr6_+_43711532	0.455	NM_014628	MAD2L1BP	MAD2L1 binding protein
chr11_-_62170659	0.454		GANAB	glucosidase, alpha; neutral AB
chr4_+_146623405	0.453	NM_001003688	SMAD1	SMAD family member 1
chr15_-_63069280	0.451	NM_001127890 NM_016630	SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr20_-_33198555	0.451		EDEM2	ER degradation enhancer, mannosidase alpha-like 2
chr13_+_110604071	0.450		ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr2_+_175292771	0.449		H3F3A	H3 histone, family 3A
chr1_+_93317374	0.449	NM_001164391 NM_001164392 NM_001164393 NM_007358	MTF2	metal response element binding transcription factor 2
chr4_-_48477038	0.448	NM_015030	FRYL	FRY-like
chr4_+_57028536	0.447		SRP72	signal recognition particle 72kDa
chr4_+_186554958	0.447		ANKRD37	ankyrin repeat domain 37
chr22_+_36365393	0.445
chrX_-_7855764	0.445	NM_001142389 NM_001172672	PNPLA4	patatin-like phospholipase domain containing 4
chr2_-_174968595	0.445	NM_004882	CIR1	corepressor interacting with RBPJ, 1
chr19_-_51909416	0.444	NM_001079882	PRKD2	protein kinase D2
chr8_+_28803949	0.442	NM_024567	HMBOX1	homeobox containing 1
chr3_-_57088332	0.442	NM_001128615	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chrX_-_19815526	0.441		SH3KBP1	SH3-domain kinase binding protein 1
chr17_-_52346397	0.441	NM_005082	TRIM25	tripartite motif containing 25
chr16_+_68890559	0.441	NM_001014449 NM_001014451 NM_007242	DDX19B	DEAD (Asp-Glu-Ala-As) box polypeptide 19B
chr15_+_75500284	0.440	NM_018200	HMG20A	high-mobility group 20A
chr12_+_11693993	0.440	NM_001987	ETV6	ets variant 6
chr8_+_56848552	0.440		TGS1	trimethylguanosine synthase 1
chr1_-_35795592	0.439	NM_024874	KIAA0319L	KIAA0319-like
chr4_-_155753249	0.437		FGG	fibrinogen gamma chain
chr17_-_46692369	0.436	NM_017643	MBTD1	mbt domain containing 1
chr1_+_94656517	0.436	NM_001122674 NM_002858	ABCD3	ATP-binding cassette, sub-family D (ALD), member 3
chr14_-_74713012	0.436		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr3_+_44571600	0.436	NM_018651 NM_025169	ZNF167	zinc finger protein 167
chr10_-_43212703	0.435	NM_001098207	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr1_-_17637576	0.435		RCC2	regulator of chromosome condensation 2
chrX_+_153908257	0.435	NM_023934	FUNDC2	FUN14 domain containing 2
chr2_+_239000395	0.435		ASB1	ankyrin repeat and SOCS box containing 1
chr5_-_32348826	0.434	NM_001040446	MTMR12	myotubularin related protein 12
chr2_+_198089036	0.433		MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)
chr9_-_35093144	0.432	NM_013442	STOML2	stomatin (EPB72)-like 2
chr18_-_50004770	0.432		MBD2	methyl-CpG binding domain protein 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.35	9.60e-57	GO:0044260	cellular macromolecule metabolic process
1.24	4.01e-44	GO:0044237	cellular metabolic process
1.29	1.62e-43	GO:0043170	macromolecule metabolic process
1.40	1.67e-38	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	1.58e-36	GO:0044238	primary metabolic process
1.43	4.97e-35	GO:0090304	nucleic acid metabolic process
1.19	2.96e-32	GO:0008152	metabolic process
1.44	8.12e-30	GO:0010467	gene expression
1.45	2.70e-28	GO:0016070	RNA metabolic process
1.31	2.73e-28	GO:0034641	cellular nitrogen compound metabolic process
1.30	1.17e-26	GO:0006807	nitrogen compound metabolic process
1.35	2.79e-26	GO:0044267	cellular protein metabolic process
1.41	1.30e-22	GO:0009059	macromolecule biosynthetic process
1.41	3.29e-22	GO:0034645	cellular macromolecule biosynthetic process
1.70	3.25e-19	GO:0016071	mRNA metabolic process
1.63	4.42e-19	GO:0006396	RNA processing
1.24	1.03e-17	GO:0071840	cellular component organization or biogenesis
1.36	7.36e-17	GO:0006996	organelle organization
1.25	1.50e-16	GO:0019538	protein metabolic process
1.75	7.55e-16	GO:0006397	mRNA processing
1.45	9.90e-16	GO:0007049	cell cycle
1.26	3.18e-15	GO:0071841	cellular component organization or biogenesis at cellular level
1.27	4.49e-15	GO:0044249	cellular biosynthetic process
1.23	5.94e-15	GO:0060255	regulation of macromolecule metabolic process
1.51	6.58e-15	GO:0046907	intracellular transport
1.48	1.62e-14	GO:0015031	protein transport
1.08	3.46e-14	GO:0009987	cellular process
1.47	3.50e-14	GO:0045184	establishment of protein localization
1.21	6.66e-14	GO:0031323	regulation of cellular metabolic process
1.57	6.90e-14	GO:0000278	mitotic cell cycle
1.26	7.24e-14	GO:0009058	biosynthetic process
1.26	7.45e-14	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.21	1.40e-13	GO:0016043	cellular component organization
1.37	2.14e-13	GO:0033036	macromolecule localization
1.98	2.41e-13	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.98	2.41e-13	GO:0000398	nuclear mRNA splicing, via spliceosome
1.47	6.21e-13	GO:0022402	cell cycle process
1.94	1.07e-12	GO:0000375	RNA splicing, via transesterification reactions
1.54	1.10e-12	GO:0009057	macromolecule catabolic process
1.40	1.15e-12	GO:0008104	protein localization
1.25	1.51e-12	GO:0010556	regulation of macromolecule biosynthetic process
1.19	1.65e-12	GO:0019222	regulation of metabolic process
1.58	1.67e-12	GO:0044265	cellular macromolecule catabolic process
1.76	2.23e-12	GO:0008380	RNA splicing
1.50	2.60e-12	GO:0022403	cell cycle phase
1.20	5.29e-12	GO:0080090	regulation of primary metabolic process
1.57	6.48e-12	GO:0006974	response to DNA damage stimulus
1.24	9.23e-12	GO:0010468	regulation of gene expression
1.70	2.23e-11	GO:0070647	protein modification by small protein conjugation or removal
1.88	4.36e-11	GO:0071843	cellular component biogenesis at cellular level
1.23	7.32e-11	GO:0071842	cellular component organization at cellular level
1.89	9.55e-11	GO:0022613	ribonucleoprotein complex biogenesis
1.34	1.07e-10	GO:0051641	cellular localization
1.70	1.55e-10	GO:0006412	translation
1.64	2.19e-10	GO:0030163	protein catabolic process
1.27	3.11e-10	GO:0006464	protein modification process
1.36	3.12e-10	GO:0051649	establishment of localization in cell
1.35	5.35e-10	GO:0044248	cellular catabolic process
1.22	5.93e-10	GO:0031326	regulation of cellular biosynthetic process
1.26	7.25e-10	GO:0043412	macromolecule modification
1.41	8.24e-10	GO:0033554	cellular response to stress
1.21	8.58e-10	GO:0051171	regulation of nitrogen compound metabolic process
1.21	1.14e-09	GO:0009889	regulation of biosynthetic process
1.71	1.82e-09	GO:0032446	protein modification by small protein conjugation
1.23	2.43e-09	GO:0051252	regulation of RNA metabolic process
1.72	3.45e-09	GO:0016567	protein ubiquitination
1.63	3.56e-09	GO:0044257	cellular protein catabolic process
1.57	3.84e-09	GO:0016032	viral reproduction
1.64	4.43e-09	GO:0043632	modification-dependent macromolecule catabolic process
1.46	6.01e-09	GO:0051726	regulation of cell cycle
1.63	6.05e-09	GO:0051603	proteolysis involved in cellular protein catabolic process
1.64	8.99e-09	GO:0006511	ubiquitin-dependent protein catabolic process
1.63	1.23e-08	GO:0019941	modification-dependent protein catabolic process
1.20	1.72e-08	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	1.06e-07	GO:0006355	regulation of transcription, DNA-dependent
1.39	1.37e-07	GO:0016192	vesicle-mediated transport
1.64	2.52e-07	GO:0010608	posttranscriptional regulation of gene expression
1.56	3.80e-07	GO:0010564	regulation of cell cycle process
1.33	5.00e-07	GO:0032774	RNA biosynthetic process
1.27	5.24e-07	GO:0009056	catabolic process
1.59	5.51e-07	GO:0051325	interphase
1.60	5.76e-07	GO:0051329	interphase of mitotic cell cycle
1.43	6.21e-07	GO:0006259	DNA metabolic process
1.09	7.53e-07	GO:0050789	regulation of biological process
1.29	1.30e-06	GO:0044085	cellular component biogenesis
1.34	1.88e-06	GO:0008219	cell death
1.34	2.28e-06	GO:0016265	death
1.10	2.41e-06	GO:0050794	regulation of cellular process
1.89	2.53e-06	GO:0042254	ribosome biogenesis
1.34	2.94e-06	GO:0043933	macromolecular complex subunit organization
1.37	3.06e-06	GO:0006915	apoptosis
1.67	3.13e-06	GO:0071156	regulation of cell cycle arrest
1.57	3.65e-06	GO:0048285	organelle fission
1.36	4.06e-06	GO:0012501	programmed cell death
1.67	6.33e-06	GO:0000075	cell cycle checkpoint
1.56	1.16e-05	GO:0000280	nuclear division
1.56	1.16e-05	GO:0007067	mitosis
1.55	1.22e-05	GO:0000087	M phase of mitotic cell cycle
1.08	1.33e-05	GO:0065007	biological regulation
1.42	1.48e-05	GO:0070727	cellular macromolecule localization
1.38	2.12e-05	GO:0051276	chromosome organization
1.41	2.49e-05	GO:0034613	cellular protein localization
1.50	2.52e-05	GO:0051301	cell division
1.31	4.88e-05	GO:0006351	transcription, DNA-dependent
1.46	6.19e-05	GO:0006886	intracellular protein transport
1.48	7.29e-05	GO:0044419	interspecies interaction between organisms
1.49	8.83e-05	GO:0006281	DNA repair
1.53	2.12e-04	GO:0007346	regulation of mitotic cell cycle
1.46	2.35e-04	GO:0016568	chromatin modification
2.39	2.36e-04	GO:0006413	translational initiation
1.46	2.67e-04	GO:0018193	peptidyl-amino acid modification
1.42	2.82e-04	GO:0000279	M phase
1.91	3.00e-04	GO:0006352	transcription initiation, DNA-dependent
1.25	3.34e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.67	3.63e-04	GO:0006417	regulation of translation
1.32	4.90e-04	GO:0065003	macromolecular complex assembly
1.90	7.88e-04	GO:0071826	ribonucleoprotein complex subunit organization
1.16	8.16e-04	GO:0048522	positive regulation of cellular process
1.23	8.43e-04	GO:0009893	positive regulation of metabolic process
1.27	8.67e-04	GO:0031324	negative regulation of cellular metabolic process
1.81	8.79e-04	GO:0007059	chromosome segregation
1.91	9.20e-04	GO:0000236	mitotic prometaphase
1.73	1.16e-03	GO:0007093	mitotic cell cycle checkpoint
1.34	1.27e-03	GO:0071822	protein complex subunit organization
1.60	1.28e-03	GO:0006260	DNA replication
1.48	1.51e-03	GO:0006366	transcription from RNA polymerase II promoter
1.27	1.51e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.23	1.60e-03	GO:0031325	positive regulation of cellular metabolic process
1.51	1.67e-03	GO:0051248	negative regulation of protein metabolic process
1.25	1.75e-03	GO:0043067	regulation of programmed cell death
1.25	1.90e-03	GO:0032268	regulation of cellular protein metabolic process
1.25	1.95e-03	GO:0042981	regulation of apoptosis
1.36	2.01e-03	GO:0034621	cellular macromolecular complex subunit organization
1.90	2.07e-03	GO:0022618	ribonucleoprotein complex assembly
1.24	2.56e-03	GO:0010941	regulation of cell death
1.63	2.86e-03	GO:0010498	proteasomal protein catabolic process
1.63	2.86e-03	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.14	3.87e-03	GO:0048518	positive regulation of biological process
1.50	3.89e-03	GO:0032269	negative regulation of cellular protein metabolic process
1.23	4.68e-03	GO:0051246	regulation of protein metabolic process
1.59	4.99e-03	GO:0043687	post-translational protein modification
1.34	5.24e-03	GO:0043068	positive regulation of programmed cell death
1.79	5.77e-03	GO:0051340	regulation of ligase activity
1.52	5.86e-03	GO:0048011	nerve growth factor receptor signaling pathway
1.64	7.08e-03	GO:0000082	G1/S transition of mitotic cell cycle
1.33	7.72e-03	GO:0010942	positive regulation of cell death
1.80	8.12e-03	GO:0051438	regulation of ubiquitin-protein ligase activity
1.34	8.23e-03	GO:0043065	positive regulation of apoptosis
1.24	8.55e-03	GO:0009892	negative regulation of metabolic process
1.87	8.88e-03	GO:0006354	transcription elongation, DNA-dependent
1.87	1.04e-02	GO:0006353	transcription termination, DNA-dependent
1.80	1.14e-02	GO:0030330	DNA damage response, signal transduction by p53 class mediator
1.51	1.16e-02	GO:0033365	protein localization to organelle
1.71	1.21e-02	GO:0016197	endosome transport
1.69	1.23e-02	GO:0031570	DNA integrity checkpoint
1.81	1.60e-02	GO:0051351	positive regulation of ligase activity
1.44	2.14e-02	GO:0034660	ncRNA metabolic process
1.82	2.24e-02	GO:0051443	positive regulation of ubiquitin-protein ligase activity
1.91	2.30e-02	GO:0006367	transcription initiation from RNA polymerase II promoter
1.76	2.66e-02	GO:0006364	rRNA processing
1.32	3.01e-02	GO:0070271	protein complex biogenesis
1.22	3.05e-02	GO:0022607	cellular component assembly
1.50	3.48e-02	GO:0006457	protein folding
1.33	3.54e-02	GO:0006325	chromatin organization
1.68	3.59e-02	GO:0000077	DNA damage checkpoint
1.60	4.50e-02	GO:0048193	Golgi vesicle transport
1.32	4.62e-02	GO:0006461	protein complex assembly
1.33	4.76e-02	GO:0016044	cellular membrane organization
1.62	4.84e-02	GO:0006403	RNA localization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	1.72e-83	GO:0044424	intracellular part
1.16	6.62e-83	GO:0005622	intracellular
1.23	4.81e-79	GO:0043231	intracellular membrane-bounded organelle
1.23	1.46e-78	GO:0043227	membrane-bounded organelle
1.20	4.41e-73	GO:0043229	intracellular organelle
1.19	4.57e-72	GO:0043226	organelle
1.30	2.81e-61	GO:0005634	nucleus
1.49	1.16e-47	GO:0044428	nuclear part
1.45	1.97e-44	GO:0031974	membrane-enclosed lumen
1.46	9.38e-44	GO:0070013	intracellular organelle lumen
1.46	1.03e-43	GO:0043233	organelle lumen
1.50	1.94e-40	GO:0031981	nuclear lumen
1.24	1.51e-38	GO:0044446	intracellular organelle part
1.23	7.30e-37	GO:0044422	organelle part
1.16	3.35e-33	GO:0005737	cytoplasm
1.20	1.11e-30	GO:0044444	cytoplasmic part
1.38	8.87e-27	GO:0005829	cytosol
1.47	8.87e-25	GO:0005654	nucleoplasm
1.26	1.13e-23	GO:0032991	macromolecular complex
1.68	1.11e-18	GO:0005730	nucleolus
1.26	8.34e-18	GO:0043228	non-membrane-bounded organelle
1.26	8.34e-18	GO:0043232	intracellular non-membrane-bounded organelle
1.63	2.79e-16	GO:0030529	ribonucleoprotein complex
1.22	6.17e-14	GO:0043234	protein complex
1.04	7.72e-11	GO:0044464	cell part
1.04	8.57e-11	GO:0005623	cell
1.98	7.88e-10	GO:0005681	spliceosomal complex
1.41	1.63e-09	GO:0044451	nucleoplasm part
1.46	7.28e-09	GO:0005694	chromosome
1.85	1.81e-07	GO:0000151	ubiquitin ligase complex
2.09	1.14e-06	GO:0071013	catalytic step 2 spliceosome
1.60	6.87e-06	GO:0016604	nuclear body
1.74	1.73e-05	GO:0000793	condensed chromosome
1.59	3.63e-05	GO:0000228	nuclear chromosome
1.39	4.84e-05	GO:0044427	chromosomal part
1.22	7.02e-05	GO:0005739	mitochondrion
1.30	1.81e-04	GO:0031967	organelle envelope
1.16	2.68e-04	GO:0031090	organelle membrane
1.43	3.23e-04	GO:0005815	microtubule organizing center
1.66	3.31e-04	GO:0000775	chromosome, centromeric region
1.28	4.41e-04	GO:0031975	envelope
1.59	5.51e-04	GO:0044454	nuclear chromosome part
1.70	5.51e-04	GO:0016607	nuclear speck
1.49	5.61e-04	GO:0005635	nuclear envelope
1.85	7.25e-04	GO:0030027	lamellipodium
1.82	8.20e-04	GO:0000776	kinetochore
1.55	1.41e-03	GO:0005819	spindle
2.34	2.86e-03	GO:0030532	small nuclear ribonucleoprotein complex
1.53	3.46e-03	GO:0031252	cell leading edge
1.80	5.45e-03	GO:0031461	cullin-RING ubiquitin ligase complex
1.46	5.63e-03	GO:0005813	centrosome
1.74	6.24e-03	GO:0001726	ruffle
1.26	6.66e-03	GO:0015630	microtubule cytoskeleton
1.80	7.67e-03	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
1.21	9.03e-03	GO:0005794	Golgi apparatus
1.81	9.09e-03	GO:0000777	condensed chromosome kinetochore
1.50	9.83e-03	GO:0005840	ribosome
1.78	9.91e-03	GO:0000779	condensed chromosome, centromeric region
1.89	2.54e-02	GO:0005798	Golgi-associated vesicle
1.77	3.59e-02	GO:0005643	nuclear pore
1.81	3.94e-02	GO:0016363	nuclear matrix
1.51	4.11e-02	GO:0031965	nuclear membrane
1.56	4.17e-02	GO:0019867	outer membrane
1.15	4.48e-02	GO:0012505	endomembrane system

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.21	2.86e-47	GO:0005515	protein binding
1.10	2.85e-34	GO:0005488	binding
1.29	6.00e-28	GO:0003676	nucleic acid binding
1.61	4.59e-25	GO:0003723	RNA binding
1.21	1.39e-08	GO:0000166	nucleotide binding
1.22	2.34e-08	GO:0008270	zinc ion binding
1.19	6.17e-07	GO:0003677	DNA binding
1.11	7.11e-07	GO:0003824	catalytic activity
1.21	4.75e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.20	8.53e-06	GO:0017076	purine nucleotide binding
1.46	1.43e-05	GO:0003712	transcription cofactor activity
1.20	1.44e-05	GO:0032553	ribonucleotide binding
1.20	1.44e-05	GO:0032555	purine ribonucleotide binding
1.46	1.80e-05	GO:0000988	protein binding transcription factor activity
1.46	1.80e-05	GO:0000989	transcription factor binding transcription factor activity
2.00	2.51e-05	GO:0008135	translation factor activity, nucleic acid binding
1.17	6.03e-05	GO:0046914	transition metal ion binding
1.39	9.76e-05	GO:0016874	ligase activity
1.21	1.44e-04	GO:0005524	ATP binding
1.20	1.92e-04	GO:0030554	adenyl nucleotide binding
1.20	2.90e-04	GO:0032559	adenyl ribonucleotide binding
1.18	3.78e-04	GO:0016740	transferase activity
1.28	6.14e-04	GO:0019899	enzyme binding
1.51	1.24e-03	GO:0003713	transcription coactivator activity
2.13	1.35e-03	GO:0003743	translation initiation factor activity
1.46	6.39e-03	GO:0019787	small conjugating protein ligase activity
1.47	7.17e-03	GO:0004842	ubiquitin-protein ligase activity
1.53	7.64e-03	GO:0016741	transferase activity, transferring one-carbon groups
1.54	8.20e-03	GO:0008168	methyltransferase activity
1.25	9.40e-03	GO:0017111	nucleoside-triphosphatase activity
1.24	1.41e-02	GO:0016462	pyrophosphatase activity
1.24	1.41e-02	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.23	2.01e-02	GO:0016817	hydrolase activity, acting on acid anhydrides