Motif ID: ELF1,2,4.p2

Z-value: 0.671


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF1chr13_-_405330720.674.2e-03Click!
ELF2chr4_-_1402249140.572.1e-02Click!
ELF4chrX_-_129072152-0.243.8e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_36365640 1.309 SH3BP1
SH3-domain binding protein 1
chr5_+_61910318 1.197 NM_181506
 LRRC70
leucine rich repeat containing 70
chr9_-_34116549 1.189 DCAF12
DDB1 and CUL4 associated factor 12
chr20_-_2589476 1.148 IDH3B
isocitrate dehydrogenase 3 (NAD+) beta
chr9_-_34116688 1.123 DCAF12
DDB1 and CUL4 associated factor 12
chr10_-_116434364 1.086 NM_001003407
NM_001003408
 ABLIM1

actin binding LIM protein 1

chr13_+_110653407 1.037 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr5_+_153805761 1.003 SAP30L
SAP30-like
chr9_-_34116703 0.947 NM_015397
 DCAF12
DDB1 and CUL4 associated factor 12
chr2_-_230494956 0.919 TRIP12
thyroid hormone receptor interactor 12
chr18_+_54489658 0.876 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr2_-_230494862 0.876 NM_004238
 TRIP12
thyroid hormone receptor interactor 12
chr9_-_88159143 0.863 NM_001185059
NM_001185074
NM_024617
 ZCCHC6


zinc finger, CCHC domain containing 6


chr1_-_111308017 0.861 NM_001006945
NM_018372
 C1orf103

chromosome 1 open reading frame 103

chr18_+_54489597 0.855 NM_006785
NM_173844
 MALT1

mucosa associated lymphoid tissue lymphoma translocation gene 1

chr21_-_32906729 0.844 NM_021254
 C21orf59
chromosome 21 open reading frame 59
chr1_+_153445113 0.826 NM_002455
NM_198883
 MTX1

metaxin 1

chr10_-_89567863 0.821 NM_032810
 ATAD1
ATPase family, AAA domain containing 1
chr4_-_48477021 0.802 FRYL
FRY-like
chr8_-_57149588 0.800 NM_001023
NM_001146227
 RPS20

ribosomal protein S20


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 169 entries
enrichment   p-value GO term description
2.39 2.36e-04 GO:0006413 translational initiation
1.98 2.41e-13 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.98 2.41e-13 GO:0000398 nuclear mRNA splicing, via spliceosome
1.94 1.07e-12 GO:0000375 RNA splicing, via transesterification reactions
1.91 3.00e-04 GO:0006352 transcription initiation, DNA-dependent
1.91 9.20e-04 GO:0000236 mitotic prometaphase
1.91 2.30e-02 GO:0006367 transcription initiation from RNA polymerase II promoter
1.90 7.88e-04 GO:0071826 ribonucleoprotein complex subunit organization
1.90 2.07e-03 GO:0022618 ribonucleoprotein complex assembly
1.89 9.55e-11 GO:0022613 ribonucleoprotein complex biogenesis
1.89 2.53e-06 GO:0042254 ribosome biogenesis
1.88 4.36e-11 GO:0071843 cellular component biogenesis at cellular level
1.87 8.88e-03 GO:0006354 transcription elongation, DNA-dependent
1.87 1.04e-02 GO:0006353 transcription termination, DNA-dependent
1.82 2.24e-02 GO:0051443 positive regulation of ubiquitin-protein ligase activity
1.81 8.79e-04 GO:0007059 chromosome segregation
1.81 1.60e-02 GO:0051351 positive regulation of ligase activity
1.80 8.12e-03 GO:0051438 regulation of ubiquitin-protein ligase activity
1.80 1.14e-02 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.79 5.77e-03 GO:0051340 regulation of ligase activity

Gene overrepresentation in compartment category:

Showing 1 to 20 of 64 entries
enrichment   p-value GO term description
2.34 2.86e-03 GO:0030532 small nuclear ribonucleoprotein complex
2.09 1.14e-06 GO:0071013 catalytic step 2 spliceosome
1.98 7.88e-10 GO:0005681 spliceosomal complex
1.89 2.54e-02 GO:0005798 Golgi-associated vesicle
1.85 1.81e-07 GO:0000151 ubiquitin ligase complex
1.85 7.25e-04 GO:0030027 lamellipodium
1.82 8.20e-04 GO:0000776 kinetochore
1.81 9.09e-03 GO:0000777 condensed chromosome kinetochore
1.81 3.94e-02 GO:0016363 nuclear matrix
1.80 5.45e-03 GO:0031461 cullin-RING ubiquitin ligase complex
1.80 7.67e-03 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
1.78 9.91e-03 GO:0000779 condensed chromosome, centromeric region
1.77 3.59e-02 GO:0005643 nuclear pore
1.74 1.73e-05 GO:0000793 condensed chromosome
1.74 6.24e-03 GO:0001726 ruffle
1.70 5.51e-04 GO:0016607 nuclear speck
1.68 1.11e-18 GO:0005730 nucleolus
1.66 3.31e-04 GO:0000775 chromosome, centromeric region
1.63 2.79e-16 GO:0030529 ribonucleoprotein complex
1.60 6.87e-06 GO:0016604 nuclear body

Gene overrepresentation in function category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
2.13 1.35e-03 GO:0003743 translation initiation factor activity
2.00 2.51e-05 GO:0008135 translation factor activity, nucleic acid binding
1.61 4.59e-25 GO:0003723 RNA binding
1.54 8.20e-03 GO:0008168 methyltransferase activity
1.53 7.64e-03 GO:0016741 transferase activity, transferring one-carbon groups
1.51 1.24e-03 GO:0003713 transcription coactivator activity
1.47 7.17e-03 GO:0004842 ubiquitin-protein ligase activity
1.46 1.43e-05 GO:0003712 transcription cofactor activity
1.46 1.80e-05 GO:0000988 protein binding transcription factor activity
1.46 1.80e-05 GO:0000989 transcription factor binding transcription factor activity
1.46 6.39e-03 GO:0019787 small conjugating protein ligase activity
1.39 9.76e-05 GO:0016874 ligase activity
1.29 6.00e-28 GO:0003676 nucleic acid binding
1.28 6.14e-04 GO:0019899 enzyme binding
1.25 9.40e-03 GO:0017111 nucleoside-triphosphatase activity
1.24 1.41e-02 GO:0016462 pyrophosphatase activity
1.24 1.41e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.23 2.01e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.22 2.34e-08 GO:0008270 zinc ion binding
1.21 2.86e-47 GO:0005515 protein binding