Motif ID: MYB.p2

Z-value: 2.244


Transcription factors associated with MYB.p2:

Gene SymbolEntrez IDGene Name
MYB 4602 v-myb myeloblastosis viral oncogene homolog (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYBchr6_+_1355441700.421.0e-01Click!


Activity profile for motif MYB.p2.

activity profile for motif MYB.p2


Sorted Z-values histogram for motif MYB.p2

Sorted Z-values for motif MYB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_125070613 4.183 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr9_-_125070675 3.981 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr6_+_167332781 3.522 NM_007045
NM_194429
FGFR1OP

CCR6
FGFR1 oncogene partner

chemokine (C-C motif) receptor 6
chr7_+_64136078 3.031 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr7_-_126819953 2.913 NM_176814
ZNF800
zinc finger protein 800
chr1_-_153799186 2.903 ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr1_-_201043000 2.784 KDM5B
lysine (K)-specific demethylase 5B
chr2_+_61098200 2.749 NM_002618
PEX13
peroxisomal biogenesis factor 13
chr9_+_4669557 2.626 NM_017913
CDC37L1
cell division cycle 37 homolog (S. cerevisiae)-like 1
chr1_+_42920683 2.546 YBX1
Y box binding protein 1
chr2_+_61098355 2.530 PEX13
peroxisomal biogenesis factor 13
chr11_-_129689524 2.408 ZBTB44
zinc finger and BTB domain containing 44
chr3_+_142569988 2.372 ZBTB38
zinc finger and BTB domain containing 38
chr17_-_46553083 2.367 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr1_-_114156387 2.351 RSBN1
round spermatid basic protein 1
chrX_+_130985316 2.271 NM_001042452
MST4
serine/threonine protein kinase MST4
chr1_-_114156429 2.179 NM_018364
RSBN1
round spermatid basic protein 1
chr7_+_64975596 2.167 NM_173517
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr6_+_42896771 2.118 NM_015349
KIAA0240
KIAA0240
chr2_+_85619797 2.105 NM_005911
MAT2A
methionine adenosyltransferase II, alpha
chr11_+_61861458 2.096 ASRGL1
asparaginase like 1
chr11_+_34029764 2.050 NM_005898
NM_203364
CAPRIN1

cell cycle associated protein 1

chr4_+_128922852 1.968 NM_014278
HSPA4L
heat shock 70kDa protein 4-like
chr7_+_7974941 1.933 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr4_+_129201933 1.920 LARP1B
La ribonucleoprotein domain family, member 1B
chr2_-_176575171 1.902 NM_030650
KIAA1715
KIAA1715
chr2_-_38683572 1.883 HNRPLL
heterogeneous nuclear ribonucleoprotein L-like
chr2_-_86704446 1.860 RNF103
ring finger protein 103
chr4_+_129201952 1.857 NM_018078
NM_032239
NM_178043
LARP1B


La ribonucleoprotein domain family, member 1B


chrX_+_117992623 1.844 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr2_-_38683585 1.833 NM_001142650
NM_138394
HNRPLL

heterogeneous nuclear ribonucleoprotein L-like

chr1_-_114855281 1.826 NM_015906
NM_033020
TRIM33

tripartite motif containing 33

chr17_+_50697319 1.816 NM_002126
HLF
hepatic leukemia factor
chr1_+_29086206 1.815 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr7_+_64975778 1.734 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr1_-_100370994 1.711 NM_194292
SASS6
spindle assembly 6 homolog (C. elegans)
chr16_+_19442679 1.710 NM_001199022
NM_014711
CP110

CP110 protein

chr4_+_128922930 1.706 HSPA4L
heat shock 70kDa protein 4-like
chr2_+_85619802 1.700 MAT2A
methionine adenosyltransferase II, alpha
chr4_+_129201854 1.688 LARP1B
La ribonucleoprotein domain family, member 1B
chr8_-_53789544 1.646 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr22_-_20235372 1.637 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr10_+_92970487 1.611 PCGF5
polycomb group ring finger 5
chr1_+_108765634 1.582 LOC400768
hypothetical LOC400768
chr2_-_86704470 1.581 NM_001198951
NM_001198952
NM_005667
RNF103


ring finger protein 103


chr1_+_29086156 1.548 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr6_-_27548438 1.536 NM_007149
ZNF184
zinc finger protein 184
chr17_-_17050326 1.521 PLD6
phospholipase D family, member 6
chr12_-_55368323 1.510 NM_006601
PTGES3
prostaglandin E synthase 3 (cytosolic)
chr14_-_22840249 1.497


chr1_+_32251988 1.484 NM_006559
KHDRBS1
KH domain containing, RNA binding, signal transduction associated 1
chr20_+_57942213 1.476 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr2_-_61098867 1.476 NM_144709
PUS10
pseudouridylate synthase 10
chr10_-_59697636 1.467 NM_152230
IPMK
inositol polyphosphate multikinase
chr3_-_14964620 1.460


chr4_+_128922924 1.445 HSPA4L
heat shock 70kDa protein 4-like
chr10_+_92970302 1.442 NM_032373
PCGF5
polycomb group ring finger 5
chr7_+_86112012 1.438 GRM3
glutamate receptor, metabotropic 3
chr17_+_27701251 1.435 NM_001032293
NM_001098507
NM_003457
ZNF207


zinc finger protein 207


chr8_-_53789535 1.431 RB1CC1
RB1-inducible coiled-coil 1
chr7_-_72630943 1.410 NM_012453
TBL2
transducin (beta)-like 2
chr11_+_34030465 1.407 CAPRIN1
cell cycle associated protein 1
chr7_+_30291136 1.391 ZNRF2
zinc and ring finger 2
chr10_+_21863388 1.387 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr2_+_190710730 1.387 NM_001042521
C2orf88
chromosome 2 open reading frame 88
chr2_+_170298700 1.374 KLHL23
kelch-like 23 (Drosophila)
chr8_+_96215118 1.373 NM_024613
PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr3_-_14964403 1.366


chr2_-_38683518 1.365 HNRPLL
heterogeneous nuclear ribonucleoprotein L-like
chr12_-_109390439 1.359 NM_001164373
NM_016301
GPN3

GPN-loop GTPase 3

chr11_+_34030500 1.346 CAPRIN1
cell cycle associated protein 1
chr8_+_17824790 1.336 PCM1
pericentriolar material 1
chr17_-_17050355 1.336 NM_178836
PLD6
phospholipase D family, member 6
chr12_-_109390390 1.335 GPN3
GPN-loop GTPase 3
chr8_+_96215144 1.331 PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chrX_+_130984912 1.325 NM_001042453
NM_016542
MST4

serine/threonine protein kinase MST4

chr2_-_55500450 1.316 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr17_-_50854054 1.316 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr17_+_57909979 1.310 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr2_-_38831901 1.310 NM_001031684
NM_001195446
SRSF7

serine/arginine-rich splicing factor 7

chr8_+_96215273 1.296 PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr1_-_153798776 1.292 ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr16_+_30326864 1.290 ZNF771
zinc finger protein 771
chr15_-_47700342 1.280 NM_152647
C15orf33
chromosome 15 open reading frame 33
chr5_-_43592847 1.279 NM_006451
NM_182789
PAIP1

poly(A) binding protein interacting protein 1

chr1_+_170768914 1.278 NM_016227
C1orf9
chromosome 1 open reading frame 9
chr1_+_229181417 1.271 NM_022786
ARV1
ARV1 homolog (S. cerevisiae)
chr6_+_24603145 1.269 NM_001080
NM_170740
ALDH5A1

aldehyde dehydrogenase 5 family, member A1

chr2_-_111152075 1.265 NM_004336
BUB1
budding uninhibited by benzimidazoles 1 homolog (yeast)
chr1_-_109742020 1.263 NM_002959
SORT1
sortilin 1
chr1_+_144188375 1.262 NM_153713
LIX1L
Lix1 homolog (mouse)-like
chr11_-_67645246 1.257 CHKA
choline kinase alpha
chr6_-_13819931 1.256 RANBP9
RAN binding protein 9
chr1_-_243093833 1.244 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chrX_-_18282698 1.239 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr16_-_22293097 1.234 NM_001802
CDR2
cerebellar degeneration-related protein 2, 62kDa
chr6_-_166716353 1.233 BRP44L
brain protein 44-like
chr16_+_29582480 1.227 SPN
sialophorin
chr2_-_174537021 1.227 NM_001017371
SP3
Sp3 transcription factor
chr10_-_98470164 1.224 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr1_-_243094233 1.218 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr7_+_64975784 1.216 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr7_-_87343599 1.211 NM_018843
SLC25A40
solute carrier family 25, member 40
chr13_+_27610379 1.207 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_-_177838104 1.201 NM_006164
NFE2L2
nuclear factor (erythroid-derived 2)-like 2
chr12_-_55368190 1.194 PTGES3
prostaglandin E synthase 3 (cytosolic)
chr17_+_38204335 1.188 NM_173478
CNTD1
cyclin N-terminal domain containing 1
chr16_+_84202515 1.185 NM_001134473
KIAA0182
KIAA0182
chr5_+_151131704 1.175 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr6_-_166716449 1.172 NM_016098
BRP44L
brain protein 44-like
chr4_+_129021514 1.156 NM_001190801
PLK4
polo-like kinase 4
chr10_-_43224312 1.151 NM_001098205
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr14_-_35347791 1.150 RALGAPA1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr14_-_22468393 1.147 PRMT5
protein arginine methyltransferase 5
chrX_-_102828238 1.147 NM_001142418
NM_001142423
NM_001142424
NM_001142425
NM_001142426
NM_001142429
NM_001142430
NM_012286
MORF4L2







mortality factor 4 like 2







chr8_+_17824631 1.147 NM_006197
PCM1
pericentriolar material 1
chr11_-_129689669 1.147 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr5_-_43593277 1.143 NM_183323
PAIP1
poly(A) binding protein interacting protein 1
chr1_-_224253678 1.141 NM_152608
C1orf55
chromosome 1 open reading frame 55
chr7_-_72630867 1.135 TBL2
transducin (beta)-like 2
chr17_-_41658493 1.128 NM_001193465
KIAA1267
KIAA1267
chr10_+_69314944 1.126 NM_001142498
SIRT1
sirtuin 1
chr6_+_109523388 1.125 CEP57L1
centrosomal protein 57kDa-like 1
chrX_-_132947141 1.124 GPC3
glypican 3
chr20_-_33706532 1.119 RBM12
RNA binding motif protein 12
chr1_+_170768635 1.118 NM_014283
C1orf9
chromosome 1 open reading frame 9
chr12_-_53153639 1.113 NM_144594
GTSF1
gametocyte specific factor 1
chr6_-_13819463 1.112 RANBP9
RAN binding protein 9
chr10_+_31648103 1.110 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr12_-_53153613 1.107 GTSF1
gametocyte specific factor 1
chr1_-_114855200 1.105 TRIM33
tripartite motif containing 33
chr6_-_13819622 1.104 NM_005493
RANBP9
RAN binding protein 9
chr10_+_69761773 1.104 NM_012207
NM_021644
HNRNPH3

heterogeneous nuclear ribonucleoprotein H3 (2H9)

chr7_+_104441730 1.093 NM_018682
NM_182931
MLL5

myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

chr4_-_140317686 1.086 ELF2
E74-like factor 2 (ets domain transcription factor)
chr1_-_84928473 1.086 NM_001166295
NM_001166417
NM_001166293
NM_001166294
NM_014021
SSX2IP




synovial sarcoma, X breakpoint 2 interacting protein




chr1_-_153798946 1.084 NM_018489
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr2_-_61618165 1.081 XPO1
exportin 1 (CRM1 homolog, yeast)
chr2_-_69467825 1.079 NM_002056
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr21_-_14677310 1.076 NM_006948
HSPA13
heat shock protein 70kDa family, member 13
chr3_-_184180985 1.073 NM_020640
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
chr9_+_130259006 1.069 NM_153437
ODF2
outer dense fiber of sperm tails 2
chr8_+_81560971 1.060 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr17_+_27701300 1.057 ZNF207
zinc finger protein 207
chr8_-_91065961 1.056 NBN
nibrin
chr2_+_28887203 1.055 NM_001142634
NM_182756
SPDYA

speedy homolog A (Xenopus laevis)

chr16_+_29582065 1.053 SPN
sialophorin
chr1_-_224253650 1.053 C1orf55
chromosome 1 open reading frame 55
chr7_-_72630844 1.049 TBL2
transducin (beta)-like 2
chr7_+_30291029 1.047 ZNRF2
zinc and ring finger 2
chr1_+_224317062 1.042 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr14_-_22468445 1.041 NM_001039619
NM_006109
PRMT5

protein arginine methyltransferase 5

chr2_-_9688552 1.036 NM_006826
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr1_+_51968096 1.030 OSBPL9
oxysterol binding protein-like 9
chr11_+_34030527 1.028 CAPRIN1
cell cycle associated protein 1
chr16_+_65620536 1.026 NM_001755
NM_022845
CBFB

core-binding factor, beta subunit

chr2_-_38683477 1.025 HNRPLL
heterogeneous nuclear ribonucleoprotein L-like
chr22_-_35428848 1.024 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr1_-_224253610 1.020 C1orf55
chromosome 1 open reading frame 55
chr12_-_56312879 1.019 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr7_-_87343389 1.018 SLC25A40
solute carrier family 25, member 40
chr7_+_137795387 1.014 NM_003852
NM_015905
TRIM24

tripartite motif containing 24

chr1_-_224253642 1.008 C1orf55
chromosome 1 open reading frame 55
chr2_+_160277219 1.007 NM_022826
MARCH7
membrane-associated ring finger (C3HC4) 7
chr10_+_21863579 1.005 NM_001195626
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr10_-_43224604 0.997 NM_004966
NM_001098204
HNRNPF

heterogeneous nuclear ribonucleoprotein F

chr6_+_24602995 0.997 ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr1_-_166171838 0.996 NM_015415
BRP44
brain protein 44
chr1_-_209915443 0.993 NM_002497
NEK2
NIMA (never in mitosis gene a)-related kinase 2
chr1_+_246087104 0.993 NM_015431
TRIM58
tripartite motif containing 58
chr7_-_128482059 0.981 TNPO3
transportin 3
chr11_+_74377587 0.981 NM_006656
NEU3
sialidase 3 (membrane sialidase)
chr1_+_173235728 0.979 CACYBP
calcyclin binding protein
chrX_-_132947290 0.978 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chr2_+_228045053 0.978 AGFG1
ArfGAP with FG repeats 1
chr2_+_201099093 0.977 NM_001160033
NM_001160046
NM_152524
SGOL2


shugoshin-like 2 (S. pombe)


chr12_+_119418215 0.973 NM_001037495
NM_003746
DYNLL1

dynein, light chain, LC8-type 1

chr7_+_87343850 0.968 DBF4
DBF4 homolog (S. cerevisiae)
chr5_+_56505412 0.967 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr15_-_39195701 0.967 INO80
INO80 homolog (S. cerevisiae)
chr10_+_69990050 0.966 NM_030625
TET1
tet oncogene 1
chr2_+_208839195 0.953 NM_001178000
NM_015040
NM_152671
PIKFYVE


phosphoinositide kinase, FYVE finger containing


chr1_-_153924856 0.953 YY1AP1
YY1 associated protein 1
chr2_+_227898163 0.952 MFF
mitochondrial fission factor
chr8_-_121893468 0.946 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr16_-_3225360 0.946 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr10_-_98336584 0.938 TM9SF3
transmembrane 9 superfamily member 3
chr2_-_64099935 0.935 VPS54
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr2_+_200484270 0.935 C2orf69
chromosome 2 open reading frame 69
chr1_+_93418507 0.935 NM_206886
CCDC18
coiled-coil domain containing 18
chr2_+_208839325 0.934 PIKFYVE
phosphoinositide kinase, FYVE finger containing
chr2_-_9687817 0.931 YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr16_+_48744310 0.931 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr2_+_160277273 0.931 MARCH7
membrane-associated ring finger (C3HC4) 7
chr15_+_38673734 0.930 NM_144508
NM_170589
CASC5

cancer susceptibility candidate 5

chr5_+_56505608 0.928 GPBP1
GC-rich promoter binding protein 1
chr2_-_53867488 0.924 NM_016115
NM_145863
ASB3

ankyrin repeat and SOCS box containing 3

chr1_+_224317044 0.922 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr2_-_20413838 0.921 PUM2
pumilio homolog 2 (Drosophila)
chr1_-_242681742 0.919 ADSS
adenylosuccinate synthase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 2.18e-20 GO:0044260 cellular macromolecule metabolic process
2.35 2.03e-16 GO:0000278 mitotic cell cycle
1.36 1.59e-15 GO:0043170 macromolecule metabolic process
1.94 2.79e-15 GO:0007049 cell cycle
1.60 5.83e-15 GO:0090304 nucleic acid metabolic process
2.07 6.14e-15 GO:0022402 cell cycle process
1.29 2.65e-14 GO:0044237 cellular metabolic process
2.14 4.18e-14 GO:0022403 cell cycle phase
1.49 5.32e-13 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.62 7.37e-12 GO:0016070 RNA metabolic process
1.23 1.21e-10 GO:0008152 metabolic process
1.25 1.65e-10 GO:0044238 primary metabolic process
1.40 2.44e-10 GO:0034641 cellular nitrogen compound metabolic process
2.54 2.75e-10 GO:0000087 M phase of mitotic cell cycle
1.59 5.83e-10 GO:0006996 organelle organization
1.39 6.85e-10 GO:0006807 nitrogen compound metabolic process
2.50 1.92e-09 GO:0000280 nuclear division
2.50 1.92e-09 GO:0007067 mitosis
2.46 3.19e-09 GO:0048285 organelle fission
2.17 9.09e-09 GO:0000279 M phase
1.52 1.20e-08 GO:0010467 gene expression
2.03 1.67e-08 GO:0016071 mRNA metabolic process
2.26 2.03e-08 GO:0016568 chromatin modification
1.40 2.15e-07 GO:0044267 cellular protein metabolic process
2.03 2.57e-07 GO:0006325 chromatin organization
1.89 2.97e-07 GO:0051276 chromosome organization
3.25 4.08e-07 GO:0000086 G2/M transition of mitotic cell cycle
2.12 7.08e-07 GO:0006397 mRNA processing
2.25 1.19e-06 GO:0051325 interphase
2.25 1.51e-06 GO:0051329 interphase of mitotic cell cycle
1.31 2.64e-06 GO:0071840 cellular component organization or biogenesis
2.15 4.84e-06 GO:0070647 protein modification by small protein conjugation or removal
1.30 8.33e-06 GO:0016043 cellular component organization
1.35 8.62e-06 GO:0071841 cellular component organization or biogenesis at cellular level
1.35 9.44e-06 GO:0071842 cellular component organization at cellular level
2.07 1.88e-05 GO:0051301 cell division
2.21 2.09e-05 GO:0032446 protein modification by small protein conjugation
1.29 2.68e-05 GO:0060255 regulation of macromolecule metabolic process
3.29 3.68e-05 GO:0000236 mitotic prometaphase
1.76 3.69e-05 GO:0006396 RNA processing
2.18 4.74e-05 GO:0010608 posttranscriptional regulation of gene expression
1.28 4.93e-05 GO:0080090 regulation of primary metabolic process
1.83 5.47e-05 GO:0044265 cellular macromolecule catabolic process
3.37 7.26e-05 GO:0031123 RNA 3'-end processing
2.17 1.90e-04 GO:0016567 protein ubiquitination
3.54 1.91e-04 GO:0031124 mRNA 3'-end processing
1.32 2.28e-04 GO:0010468 regulation of gene expression
1.29 3.49e-04 GO:0019538 protein metabolic process
1.26 3.58e-04 GO:0031323 regulation of cellular metabolic process
2.04 4.11e-04 GO:0008380 RNA splicing
1.24 4.24e-04 GO:0019222 regulation of metabolic process
1.38 4.37e-04 GO:0006464 protein modification process
1.41 4.40e-04 GO:0034645 cellular macromolecule biosynthetic process
1.71 4.98e-04 GO:0009057 macromolecule catabolic process
1.09 5.83e-04 GO:0009987 cellular process
1.58 6.13e-04 GO:0006351 transcription, DNA-dependent
2.02 8.59e-04 GO:0006366 transcription from RNA polymerase II promoter
1.39 1.08e-03 GO:0009059 macromolecule biosynthetic process
2.32 1.26e-03 GO:0006913 nucleocytoplasmic transport
1.53 1.43e-03 GO:0032774 RNA biosynthetic process
2.37 1.44e-03 GO:0006417 regulation of translation
2.30 1.73e-03 GO:0051169 nuclear transport
2.22 2.31e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.22 2.31e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
1.35 2.35e-03 GO:0043412 macromolecule modification
1.30 3.77e-03 GO:0048519 negative regulation of biological process
1.32 3.82e-03 GO:0048523 negative regulation of cellular process
1.52 4.48e-03 GO:0010605 negative regulation of macromolecule metabolic process
2.16 4.76e-03 GO:0000375 RNA splicing, via transesterification reactions
1.90 6.88e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.55 7.84e-03 GO:0046907 intracellular transport
1.29 8.45e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
5.33 9.81e-03 GO:0007098 centrosome cycle
1.86 1.30e-02 GO:0019941 modification-dependent protein catabolic process
2.91 1.39e-02 GO:0006338 chromatin remodeling
1.85 1.60e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.49 1.84e-02 GO:0031324 negative regulation of cellular metabolic process
1.46 2.03e-02 GO:0009892 negative regulation of metabolic process
1.28 2.14e-02 GO:0044249 cellular biosynthetic process
1.59 2.30e-02 GO:0051726 regulation of cell cycle
1.60 2.46e-02 GO:0006259 DNA metabolic process
2.29 2.48e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.27 2.59e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.91 2.72e-02 GO:0007017 microtubule-based process
2.21 2.83e-02 GO:0000226 microtubule cytoskeleton organization
2.72 2.89e-02 GO:0051168 nuclear export
1.81 2.91e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
4.82 3.11e-02 GO:0043489 RNA stabilization
4.82 3.11e-02 GO:0048255 mRNA stabilization
2.12 3.19e-02 GO:0016570 histone modification
1.28 4.17e-02 GO:0051252 regulation of RNA metabolic process
1.42 4.26e-02 GO:0051246 regulation of protein metabolic process
1.43 4.63e-02 GO:0032268 regulation of cellular protein metabolic process
2.08 4.76e-02 GO:0016569 covalent chromatin modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 5.75e-33 GO:0005622 intracellular
1.21 8.41e-33 GO:0044424 intracellular part
1.45 1.42e-32 GO:0005634 nucleus
1.26 1.88e-25 GO:0043231 intracellular membrane-bounded organelle
1.26 3.12e-25 GO:0043227 membrane-bounded organelle
1.23 7.94e-25 GO:0043229 intracellular organelle
1.23 1.91e-24 GO:0043226 organelle
1.74 2.06e-24 GO:0044428 nuclear part
1.73 2.27e-19 GO:0031981 nuclear lumen
1.32 1.07e-16 GO:0044446 intracellular organelle part
1.32 4.46e-16 GO:0044422 organelle part
1.58 1.08e-15 GO:0070013 intracellular organelle lumen
1.57 1.13e-15 GO:0043233 organelle lumen
1.56 2.35e-15 GO:0031974 membrane-enclosed lumen
1.75 3.86e-14 GO:0005654 nucleoplasm
1.37 4.91e-11 GO:0032991 macromolecular complex
1.93 2.72e-10 GO:0015630 microtubule cytoskeleton
1.99 2.20e-09 GO:0005694 chromosome
1.37 6.72e-09 GO:0043234 protein complex
1.17 8.02e-09 GO:0005737 cytoplasm
1.45 1.21e-08 GO:0005829 cytosol
2.01 6.40e-08 GO:0044427 chromosomal part
2.47 1.25e-07 GO:0005813 centrosome
1.36 1.72e-07 GO:0043228 non-membrane-bounded organelle
1.36 1.72e-07 GO:0043232 intracellular non-membrane-bounded organelle
2.63 2.06e-07 GO:0005819 spindle
2.16 2.08e-07 GO:0005815 microtubule organizing center
1.69 7.00e-06 GO:0044451 nucleoplasm part
2.55 5.20e-05 GO:0000775 chromosome, centromeric region
1.17 1.28e-04 GO:0044444 cytoplasmic part
2.06 3.89e-04 GO:0005635 nuclear envelope
1.46 9.07e-04 GO:0044430 cytoskeletal part
2.73 1.82e-03 GO:0000776 kinetochore
1.85 4.61e-03 GO:0005874 microtubule
1.98 5.11e-03 GO:0016604 nuclear body
3.63 5.52e-03 GO:0005876 spindle microtubule
2.26 5.83e-03 GO:0000151 ubiquitin ligase complex
3.54 7.72e-03 GO:0005814 centriole
2.87 8.35e-03 GO:0000922 spindle pole
2.32 8.63e-03 GO:0016607 nuclear speck
1.91 9.96e-03 GO:0000785 chromatin
4.80 1.58e-02 GO:0080008 CUL4 RING ubiquitin ligase complex
2.17 1.80e-02 GO:0000793 condensed chromosome
1.59 2.05e-02 GO:0005730 nucleolus
1.04 2.40e-02 GO:0044464 cell part
1.04 2.47e-02 GO:0005623 cell
6.75 2.88e-02 GO:0016281 eukaryotic translation initiation factor 4F complex
2.64 3.09e-02 GO:0000777 condensed chromosome kinetochore
2.78 3.65e-02 GO:0016363 nuclear matrix
2.68 3.76e-02 GO:0034399 nuclear periphery
1.55 4.36e-02 GO:0030529 ribonucleoprotein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.24 1.20e-13 GO:0005515 protein binding
1.38 5.49e-11 GO:0003676 nucleic acid binding
1.84 2.72e-10 GO:0003723 RNA binding
1.10 1.59e-07 GO:0005488 binding
3.05 8.79e-04 GO:0042393 histone binding
1.29 2.38e-03 GO:0000166 nucleotide binding
1.54 2.42e-03 GO:0019899 enzyme binding
1.88 3.03e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.28 4.14e-03 GO:0003677 DNA binding
1.89 6.64e-03 GO:0016881 acid-amino acid ligase activity
2.06 9.48e-03 GO:0003682 chromatin binding
1.94 1.04e-02 GO:0019787 small conjugating protein ligase activity
1.96 1.20e-02 GO:0004842 ubiquitin-protein ligase activity
1.61 3.42e-02 GO:0016874 ligase activity
1.66 4.59e-02 GO:0003712 transcription cofactor activity
1.66 4.97e-02 GO:0000988 protein binding transcription factor activity
1.66 4.97e-02 GO:0000989 transcription factor binding transcription factor activity