Motif ID: ATF2.p2

Z-value: 1.079


Transcription factors associated with ATF2.p2:

Gene SymbolEntrez IDGene Name
ATF2 1386 activating transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF2chr2_-_175741096-0.146.0e-01Click!


Activity profile for motif ATF2.p2.

activity profile for motif ATF2.p2


Sorted Z-values histogram for motif ATF2.p2

Sorted Z-values for motif ATF2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_42589543 1.385 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr4_-_187884721 0.997


chr8_+_70567581 0.970 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr5_-_99898788 0.959


chr2_+_220116986 0.899 NM_001005209
TMEM198
transmembrane protein 198
chr8_+_70567634 0.885 SULF1
sulfatase 1
chr4_-_186693574 0.843 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr6_+_39868116 0.832


chr13_-_51276231 0.828 NM_001031719
NM_024705
DHRS12

dehydrogenase/reductase (SDR family) member 12

chr1_+_29435534 0.820 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr6_+_39868126 0.789 DAAM2
dishevelled associated activator of morphogenesis 2
chr4_-_111777584 0.784 PITX2
paired-like homeodomain 2
chr2_+_220117009 0.765 TMEM198
transmembrane protein 198
chr11_+_12652427 0.748 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr20_-_43853945 0.729 NM_080614
WFDC3
WAP four-disulfide core domain 3
chr2_-_224175339 0.721 SCG2
secretogranin II
chr2_-_220116508 0.714 NM_024536
CHPF
chondroitin polymerizing factor
chr1_+_26368969 0.684 NM_015871
ZNF593
zinc finger protein 593
chr4_-_111777651 0.680 PITX2
paired-like homeodomain 2
chr2_-_224175293 0.667 SCG2
secretogranin II
chr9_-_19023183 0.625 NM_153707
FAM154A
family with sequence similarity 154, member A
chr11_+_61204392 0.618 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr19_-_5291700 0.610 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr4_+_658250 0.584 MYL5
myosin, light chain 5, regulatory
chr2_-_237987509 0.564 COL6A3
collagen, type VI, alpha 3
chr2_-_237987554 0.552 COL6A3
collagen, type VI, alpha 3
chr8_+_40130143 0.542 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr3_+_141136691 0.534 NM_022131
CLSTN2
calsyntenin 2
chr2_+_154436670 0.527 NM_052917
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr17_-_13445942 0.526 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr2_-_237987579 0.504 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr1_+_165330710 0.499 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr5_-_158690047 0.487 NM_002187
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr14_+_31868229 0.485 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr17_+_7402788 0.475 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_-_237987545 0.473 COL6A3
collagen, type VI, alpha 3
chr10_-_95350949 0.472 NM_006744
RBP4
retinol binding protein 4, plasma
chr8_-_67253234 0.459 NM_000756
CRH
corticotropin releasing hormone
chr15_-_81412354 0.451 NM_004839
NM_199330
NM_199331
NM_199332
HOMER2



homer homolog 2 (Drosophila)



chr9_+_110664366 0.451 NM_006687
ACTL7A
actin-like 7A
chr8_-_95343716 0.447 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr18_+_57308754 0.441 NM_031891
CDH20
cadherin 20, type 2
chr10_-_102663070 0.440


chr1_-_1283770 0.439 NM_032348
MXRA8
matrix-remodelling associated 8
chr5_+_140747586 0.438 NM_003736
NM_032098
PCDHGB4

protocadherin gamma subfamily B, 4

chr16_+_66252296 0.437 NM_001037281
NM_016948
PARD6A

par-6 partitioning defective 6 homolog alpha (C. elegans)

chr2_-_224175386 0.435 NM_003469
SCG2
secretogranin II
chr17_-_53976681 0.423 NM_001038704
C17orf47
chromosome 17 open reading frame 47
chr22_-_27787793 0.420 NM_015370
C22orf31
chromosome 22 open reading frame 31
chr3_+_189354167 0.419 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_+_18584666 0.417 NM_012109
TMEM59L
transmembrane protein 59-like
chr4_+_85723080 0.414 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr2_-_237987553 0.412 COL6A3
collagen, type VI, alpha 3
chr3_+_8518508 0.412 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr3_-_21767819 0.408 NM_024697
ZNF385D
zinc finger protein 385D
chr7_+_30140868 0.403 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr20_+_19863716 0.399 RIN2
Ras and Rab interactor 2
chr3_-_64186151 0.392 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr7_-_45095017 0.392 NM_001146334
NACAD
NAC alpha domain containing
chr2_+_38031099 0.392 NM_001170793
NM_144713
FAM82A1

family with sequence similarity 82, member A1

chr8_-_95343696 0.382 GEM
GTP binding protein overexpressed in skeletal muscle
chr13_+_51275921 0.380


chr6_-_127822227 0.378 NM_014702
KIAA0408
KIAA0408
chr1_-_42157077 0.376 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr4_-_23500706 0.372 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr2_-_70167569 0.371 LOC400960
hypothetical LOC400960
chr13_+_75232797 0.370 NM_015842
LMO7
LIM domain 7
chr10_+_24023680 0.366 NM_001098500
KIAA1217
KIAA1217
chr13_+_31503436 0.366 NM_023037
FRY
furry homolog (Drosophila)
chr2_-_206790871 0.364 NM_001098199
NM_005279
GPR1

G protein-coupled receptor 1

chr4_+_120167264 0.364 SYNPO2
synaptopodin 2
chr3_-_126136261 0.363 NM_033049
MUC13
mucin 13, cell surface associated
chr1_+_99502655 0.359 LPPR4
lipid phosphate phosphatase-related protein type 4
chr2_+_5750229 0.357 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr12_+_70119785 0.353 LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr2_-_224611568 0.352 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr11_+_76516957 0.351 NM_000260
NM_001127179
NM_001127180
MYO7A


myosin VIIA


chr14_+_20568184 0.349 NM_173846
TPPP2
tubulin polymerization-promoting protein family member 2
chr11_+_56862395 0.349 NM_002559
P2RX3
purinergic receptor P2X, ligand-gated ion channel, 3
chr1_+_17404206 0.348 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr7_-_37923040 0.345 NM_003014
SFRP4
secreted frizzled-related protein 4
chr5_+_36642424 0.341 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_79748273 0.332 NM_000793
NM_013989
DIO2

deiodinase, iodothyronine, type II

chr1_+_109090817 0.329 STXBP3
syntaxin binding protein 3
chr9_+_36159384 0.325 NM_005893
CCIN
calicin
chr1_+_119484529 0.325


chr1_+_99502435 0.324 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr19_-_55671273 0.324 FAM71E1
family with sequence similarity 71, member E1
chrX_-_83644054 0.320 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr6_-_56515640 0.320


chr11_+_108798047 0.318 NM_207645
C11orf87
chromosome 11 open reading frame 87
chr14_+_92459197 0.315 NM_001275
CHGA
chromogranin A (parathyroid secretory protein 1)
chr2_+_176680251 0.313 NM_021192
HOXD11
homeobox D11
chr20_+_9236446 0.312 NM_000933
PLCB4
phospholipase C, beta 4
chr5_+_32747194 0.312 NM_000908
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr16_+_27320983 0.311 NM_181078
NM_181079
IL21R

interleukin 21 receptor

chr3_+_141879555 0.310 NM_152616
TRIM42
tripartite motif containing 42
chr5_-_132976094 0.308 FSTL4
follistatin-like 4
chr9_+_102987137 0.307 NM_017753
LPPR1
lipid phosphate phosphatase-related protein type 1
chr6_-_106880300 0.304 NM_004849
ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr22_-_28972683 0.303 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr7_+_128099581 0.301 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr7_-_100595552 0.300 NM_003378
VGF
VGF nerve growth factor inducible
chr12_+_52680143 0.298 NM_006897
HOXC9
homeobox C9
chr7_-_6354933 0.297 NM_001037163
C7orf70
chromosome 7 open reading frame 70
chr7_-_37922902 0.296 SFRP4
secreted frizzled-related protein 4
chr17_+_39213328 0.295 NM_001136483
C17orf105
chromosome 17 open reading frame 105
chr21_-_42060266 0.294 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr21_+_38550739 0.294 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr10_-_1769669 0.292 NM_018702
ADARB2
adenosine deaminase, RNA-specific, B2
chr5_+_36642213 0.290 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr2_-_216009015 0.289 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr12_-_31773210 0.288 AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr21_-_42060334 0.287 RIPK4
receptor-interacting serine-threonine kinase 4
chr2_+_10969513 0.286 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr7_+_73080362 0.286 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chrX_-_128485121 0.285 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr11_+_116575249 0.283 NM_001001522
NM_003186
TAGLN

transgelin

chr19_+_40716153 0.282 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr17_+_38831874 0.282 NM_001661
ARL4D
ADP-ribosylation factor-like 4D
chr2_-_142605010 0.280 LRP1B
low density lipoprotein receptor-related protein 1B
chr3_+_141136896 0.279 CLSTN2
calsyntenin 2
chr20_+_2621193 0.279 NM_001110514
EBF4
early B-cell factor 4
chrX_+_84385649 0.278 NM_021998
ZNF711
zinc finger protein 711
chr4_-_171161486 0.276 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr17_+_7402315 0.275 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr3_+_8518539 0.275 LMCD1
LIM and cysteine-rich domains 1
chr11_-_66367279 0.273


chr4_+_120276386 0.271 NM_016599
MYOZ2
myozenin 2
chr13_+_28900776 0.269 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr22_+_49272078 0.268 NM_017584
MIOX
myo-inositol oxygenase
chr20_+_16676997 0.268 NM_020157
OTOR
otoraplin
chr11_-_67032675 0.268 NM_005851
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr3_+_120984246 0.267 NM_022002
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr19_+_60487345 0.266 NM_032430
BRSK1
BR serine/threonine kinase 1
chr5_-_95794416 0.264 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr11_-_8849485 0.264 ST5
suppression of tumorigenicity 5
chr16_-_3485421 0.263 NM_001080524
C16orf90
chromosome 16 open reading frame 90
chr4_+_88939725 0.263 NM_004967
IBSP
integrin-binding sialoprotein
chr20_+_32610161 0.262 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr21_-_30796278 0.260 NM_181611
KRTAP19-5
keratin associated protein 19-5
chr14_+_92721048 0.259 NM_015676
NM_001098621
C14orf109

chromosome 14 open reading frame 109

chr16_+_415606 0.258 RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr11_-_65550425 0.258 NM_053054
CATSPER1
cation channel, sperm associated 1
chr2_+_170370290 0.258 SSB
Sjogren syndrome antigen B (autoantigen La)
chr17_+_72047709 0.256 NM_001077620
PRCD
progressive rod-cone degeneration
chr21_+_38550533 0.255 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr12_+_52665196 0.254 NM_017409
HOXC10
homeobox C10
chr5_-_139992621 0.254 NM_000591
CD14
CD14 molecule
chr4_+_88790477 0.253 NM_001079911
NM_004407
DMP1

dentin matrix acidic phosphoprotein 1

chr2_-_213723298 0.253 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr6_+_89848229 0.251 PNRC1
proline-rich nuclear receptor coactivator 1
chr1_+_154297588 0.251 NM_020387
RAB25
RAB25, member RAS oncogene family
chr9_+_15542871 0.250 NM_173550
C9orf93
chromosome 9 open reading frame 93
chr2_+_219991342 0.250 NM_001927
DES
desmin
chr6_+_134800533 0.250 LOC154092
hypothetical LOC154092
chr6_-_24491498 0.249 NM_001195610
DCDC2
doublecortin domain containing 2
chr7_-_41709191 0.248 NM_002192
INHBA
inhibin, beta A
chr3_-_113842652 0.247 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr8_+_134272463 0.247 NM_003882
NM_080838
WISP1

WNT1 inducible signaling pathway protein 1

chr11_-_85107569 0.245 NM_206929
SYTL2
synaptotagmin-like 2
chr11_-_62213577 0.245 LRRN4CL
LRRN4 C-terminal like
chr5_-_95323353 0.245 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr19_+_57540493 0.240 NM_173530
ZNF610
zinc finger protein 610
chr8_-_22022757 0.240 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr8_-_124818754 0.239 NM_001003954
NM_004306
ANXA13

annexin A13

chr9_-_113585593 0.239 NM_173521
C9orf84
chromosome 9 open reading frame 84
chr4_+_3341521 0.238 NM_198227
RGS12
regulator of G-protein signaling 12
chr6_-_46566969 0.237 RCAN2
regulator of calcineurin 2
chr15_+_36776090 0.236 NM_207444
C15orf53
chromosome 15 open reading frame 53
chr12_-_90029328 0.235 LUM
lumican
chr20_+_10147455 0.235 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr21_-_35343500 0.235 RUNX1
runt-related transcription factor 1
chr2_-_27384617 0.235 NM_003353
UCN
urocortin
chr2_-_216008689 0.234 FN1
fibronectin 1
chr9_-_110658030 0.233 NM_006686
ACTL7B
actin-like 7B
chr1_-_32600430 0.233 NM_001167676
LOC100128071
hypothetical LOC100128071
chr19_-_56919032 0.232 NM_001523
HAS1
hyaluronan synthase 1
chr4_-_52578542 0.232 NM_001024611
LRRC66
leucine rich repeat containing 66
chr4_-_156517394 0.231 MAP9
microtubule-associated protein 9
chr9_+_100745531 0.230 NM_001855
COL15A1
collagen, type XV, alpha 1
chr17_+_36515166 0.230 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr12_-_115803614 0.229 NM_003806
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr19_+_60487578 0.228 BRSK1
BR serine/threonine kinase 1
chr2_+_148319033 0.228 NM_001616
ACVR2A
activin A receptor, type IIA
chr19_+_50196526 0.227 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr20_-_33489383 0.227 NM_000557
GDF5
growth differentiation factor 5
chr20_+_5839973 0.226 NM_001819
CHGB
chromogranin B (secretogranin 1)
chr14_-_49399317 0.226 RN7SL2
RNA, 7SL, cytoplasmic 2
chr3_+_108578877 0.226 NM_032600
CCDC54
coiled-coil domain containing 54
chr21_+_46369617 0.225 COL6A2
collagen, type VI, alpha 2
chr19_-_52679287 0.224 NM_007059
KPTN
kaptin (actin binding protein)
chr5_-_176760242 0.224 NM_001029886
PFN3
profilin 3
chr4_-_156517423 0.223 MAP9
microtubule-associated protein 9
chr7_+_73080387 0.223 ELN
elastin
chr12_-_49076658 0.223 NM_001145475
FAM186A
family with sequence similarity 186, member A
chr3_-_55496370 0.221 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr16_-_3008162 0.220 NM_021195
CLDN6
claudin 6
chr20_+_49008754 0.219 NM_014484
MOCS3
molybdenum cofactor synthesis 3
chr3_+_101019357 0.218 NM_032359
C3orf26
chromosome 3 open reading frame 26

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.55 1.79e-08 GO:0048731 system development
1.51 2.26e-08 GO:0048856 anatomical structure development
1.40 5.74e-06 GO:0032502 developmental process
1.42 7.30e-06 GO:0007275 multicellular organismal development
1.27 3.81e-04 GO:0032501 multicellular organismal process
1.57 2.95e-03 GO:0007399 nervous system development
1.39 3.83e-03 GO:0048518 positive regulation of biological process
1.40 6.94e-03 GO:0048522 positive regulation of cellular process
1.83 7.54e-03 GO:0030182 neuron differentiation
1.46 1.13e-02 GO:0048513 organ development
1.57 1.48e-02 GO:0051239 regulation of multicellular organismal process
2.24 1.54e-02 GO:0001501 skeletal system development
1.85 3.51e-02 GO:0048666 neuron development
1.49 3.95e-02 GO:0009653 anatomical structure morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.68 3.71e-04 GO:0044421 extracellular region part
1.73 2.01e-03 GO:0005615 extracellular space
2.16 4.88e-03 GO:0005578 proteinaceous extracellular matrix
1.99 1.49e-02 GO:0031012 extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.76 1.91e-02 GO:0005198 structural molecule activity