Motif ID: SREBF1,2.p2

Z-value: 1.261


Transcription factors associated with SREBF1,2.p2:

Gene SymbolEntrez IDGene Name
SREBF1 6720 sterol regulatory element binding transcription factor 1
SREBF2 6721 sterol regulatory element binding transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SREBF1chr17_-_17681034-0.486.0e-02Click!
SREBF2chr22_+_405590830.391.3e-01Click!


Activity profile for motif SREBF1,2.p2.

activity profile for motif SREBF1,2.p2


Sorted Z-values histogram for motif SREBF1,2.p2

Sorted Z-values for motif SREBF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SREBF1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_45410197 1.394 NM_001002265
NM_145021
MARCH8

membrane-associated ring finger (C3HC4) 8

chr6_+_160310118 1.286 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr16_+_28893525 1.206 NM_001142448
NM_001142449
NM_001142450
NM_001142451
NM_032038
SPIN1
SPNS1




spindlin 1
spinster homolog 1 (Drosophila)




chr16_-_5023934 1.197 NM_016256
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr7_+_101861007 1.177 ORAI2
ORAI calcium release-activated calcium modulator 2
chr13_+_48582389 1.173 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr16_-_28411123 1.090 NM_001042432
CLN3
ceroid-lipofuscinosis, neuronal 3
chr17_-_73636386 1.068 NM_001127198
TMC6
transmembrane channel-like 6
chr17_-_73636362 1.023 TMC6
transmembrane channel-like 6
chr3_-_4483928 1.002 SUMF1
sulfatase modifying factor 1
chr8_+_109525050 0.976 TTC35
tetratricopeptide repeat domain 35
chr1_-_153195188 0.975 NM_020524
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr14_-_34661190 0.974 NM_017917
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr8_+_109525010 0.967 NM_014673
TTC35
tetratricopeptide repeat domain 35
chr11_+_120828275 0.966 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr20_+_43953428 0.960 CTSA
cathepsin A
chr14_-_67353046 0.944 NM_015346
ZFYVE26
zinc finger, FYVE domain containing 26
chr12_+_115660468 0.943 NM_001109903
NM_032814
RNFT2

ring finger protein, transmembrane 2

chr22_+_34107087 0.939 HMOX1
heme oxygenase (decycling) 1
chr20_+_43953372 0.936 CTSA
cathepsin A
chr11_+_7491789 0.926 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr12_-_54409107 0.921 NM_001040034
NM_001780
CD63

CD63 molecule

chr1_-_28432060 0.918 DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr20_+_43953331 0.916 CTSA
cathepsin A
chr3_-_4483955 0.914 NM_001164674
NM_001164675
NM_182760
SUMF1


sulfatase modifying factor 1


chr8_-_54918389 0.904 NM_015941
NM_213619
ATP6V1H

ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

chr16_+_1341937 0.902 GNPTG
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr20_+_43953606 0.901 CTSA
cathepsin A
chr5_-_150517499 0.900 ANXA6
annexin A6
chr2_+_143603439 0.900 ARHGAP15
Rho GTPase activating protein 15
chr9_+_6747919 0.899 KDM4C
lysine (K)-specific demethylase 4C
chr14_-_19993032 0.896 NM_017807
OSGEP
O-sialoglycoprotein endopeptidase
chr19_+_1018293 0.884 HMHA1
histocompatibility (minor) HA-1
chrX_+_128741562 0.883 NM_018990
SASH3
SAM and SH3 domain containing 3
chr11_-_36267510 0.882 COMMD9
COMM domain containing 9
chr7_+_149696792 0.876 NM_001099695
NM_001099696
NM_013400
REPIN1


replication initiator 1


chr11_-_18300246 0.876 NM_007216
NM_181507
NM_181508
HPS5


Hermansky-Pudlak syndrome 5


chr11_+_7491576 0.864 NM_003621
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_-_60475558 0.858 NM_016582
SLC15A3
solute carrier family 15, member 3
chr12_+_54396086 0.850 NM_001487
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr8_-_54918099 0.844 NM_213620
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr14_-_34661156 0.842 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chrX_+_128741578 0.841 SASH3
SAM and SH3 domain containing 3
chr11_+_120828058 0.829 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr2_-_219750975 0.822 C2orf24
chromosome 2 open reading frame 24
chr16_+_1341900 0.820 NM_032520
GNPTG
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr5_-_150517454 0.820 ANXA6
annexin A6
chr3_-_4483952 0.819 SUMF1
sulfatase modifying factor 1
chr10_-_100196624 0.812 HPS1
Hermansky-Pudlak syndrome 1
chr15_+_86983038 0.808 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_+_39778016 0.802 NM_002087
GRN
granulin
chr12_+_110935644 0.801 ERP29
endoplasmic reticulum protein 29
chr1_-_28432095 0.794 NM_014280
DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr9_+_6747636 0.791 NM_001146694
NM_001146695
NM_015061
KDM4C


lysine (K)-specific demethylase 4C


chr1_-_39097904 0.785 NM_022157
RRAGC
Ras-related GTP binding C
chr1_+_181871830 0.784 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr2_+_219751145 0.779 NM_024293
FAM134A
family with sequence similarity 134, member A
chr22_-_37598176 0.778 NM_014292
CBX6
chromobox homolog 6
chr2_+_46779553 0.776 NM_014011
SOCS5
suppressor of cytokine signaling 5
chrX_-_100549561 0.775 NM_000169
GLA
galactosidase, alpha
chr5_+_133735004 0.767 UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr2_+_219751230 0.764 FAM134A
family with sequence similarity 134, member A
chr8_-_54918325 0.763 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr22_+_34025872 0.759 TOM1
target of myb1 (chicken)
chr17_-_41018291 0.754


chr2_+_219751192 0.753 FAM134A
family with sequence similarity 134, member A
chr8_-_126173186 0.751 KIAA0196
KIAA0196
chr8_-_126173189 0.749 KIAA0196
KIAA0196
chr8_+_98725505 0.741 NM_178812
MTDH
metadherin
chr3_+_114948591 0.735 ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr10_-_98021144 0.730 NM_001114094
NM_013314
BLNK

B-cell linker

chr12_-_119826073 0.725 SPPL3
signal peptide peptidase 3
chr17_-_39556535 0.724 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr8_-_126173108 0.724 KIAA0196
KIAA0196
chr16_-_28410580 0.722 NM_000086
CLN3
ceroid-lipofuscinosis, neuronal 3
chr17_-_60346042 0.716 LRRC37A3
leucine rich repeat containing 37, member A3
chr17_+_73638430 0.714 NM_152468
TMC8
transmembrane channel-like 8
chr2_+_215885063 0.713 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr4_+_17225344 0.710 NM_025205
MED28
mediator complex subunit 28
chr3_-_11585264 0.702 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr8_-_126173203 0.702 KIAA0196
KIAA0196
chr1_-_152867007 0.699 ADAR
adenosine deaminase, RNA-specific
chr13_-_31900218 0.697 NM_001079691
NM_052818
N4BP2L1

NEDD4 binding protein 2-like 1

chr5_-_150517528 0.696 NM_001155
ANXA6
annexin A6
chr2_+_227898163 0.696 MFF
mitochondrial fission factor
chr5_+_139534874 0.695 C5orf32
chromosome 5 open reading frame 32
chr8_-_54918369 0.694 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr14_-_23752498 0.692 CHMP4A
chromatin modifying protein 4A
chr15_-_70455355 0.692 NM_000520
HEXA
hexosaminidase A (alpha polypeptide)
chr1_-_152867070 0.691 NM_001025107
ADAR
adenosine deaminase, RNA-specific
chr22_+_34107051 0.691 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr17_-_3486133 0.688 NM_013276
SHPK
sedoheptulokinase
chr4_-_47160476 0.688 COMMD8
COMM domain containing 8
chr12_-_54409015 0.682 CD63
CD63 molecule
chr5_+_133734768 0.665 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chrX_-_100549444 0.665 GLA
galactosidase, alpha
chr20_+_46971618 0.663 NM_006420
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr7_+_149696901 0.662 REPIN1
replication initiator 1
chr11_+_75203859 0.661 NM_003369
UVRAG
UV radiation resistance associated gene
chr19_+_1018536 0.659 HMHA1
histocompatibility (minor) HA-1
chr16_-_1465007 0.656 CLCN7
chloride channel 7
chr18_-_19271814 0.650 NM_032933
C18orf45
chromosome 18 open reading frame 45
chr11_+_75203884 0.650 UVRAG
UV radiation resistance associated gene
chr5_-_150583842 0.645 NM_015621
CCDC69
coiled-coil domain containing 69
chr8_-_126173055 0.632 KIAA0196
KIAA0196
chr14_-_23752507 0.628 CHMP4A
chromatin modifying protein 4A
chr5_-_150583808 0.627 CCDC69
coiled-coil domain containing 69
chr9_-_37566248 0.627 NM_012166
FBXO10
F-box protein 10
chr5_-_43638860 0.627


chr14_-_34660902 0.626 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr9_+_114953087 0.623 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr17_-_39556483 0.622 HDAC5
histone deacetylase 5
chr7_-_2320536 0.615 SNX8
sorting nexin 8
chr1_-_224253678 0.609 NM_152608
C1orf55
chromosome 1 open reading frame 55
chr8_+_142471290 0.607


chr17_+_39778180 0.606 GRN
granulin
chr18_+_54958095 0.601 NM_033280
SEC11C
SEC11 homolog C (S. cerevisiae)
chr2_-_25328452 0.588 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_-_71487038 0.588 ACOX1
acyl-CoA oxidase 1, palmitoyl
chr2_+_219751207 0.588 FAM134A
family with sequence similarity 134, member A
chr9_+_94127747 0.582 CENPP
centromere protein P
chr2_+_169021001 0.576 LASS6
LAG1 homolog, ceramide synthase 6
chr8_-_143482433 0.574 NM_145003
TSNARE1
t-SNARE domain containing 1
chr16_+_273118 0.572 NM_006849
PDIA2
protein disulfide isomerase family A, member 2
chrX_+_100549861 0.566 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr17_+_39778153 0.561 GRN
granulin
chr1_-_159459999 0.560 NM_001643
APOA2
apolipoprotein A-II
chr4_-_47160403 0.558 NM_017845
COMMD8
COMM domain containing 8
chr10_-_120504659 0.558 NM_153810
C10orf46
chromosome 10 open reading frame 46
chr8_-_126173227 0.557 NM_014846
KIAA0196
KIAA0196
chr22_-_35232979 0.552 FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr16_+_87450991 0.546 NM_016209
TRAPPC2L
trafficking protein particle complex 2-like
chr1_-_152797820 0.546 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr12_+_110935618 0.546 ERP29
endoplasmic reticulum protein 29
chr17_+_39778191 0.540 GRN
granulin
chr14_-_93512818 0.539 ASB2
ankyrin repeat and SOCS box containing 2
chr1_+_44213260 0.538 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr8_+_98725604 0.537 MTDH
metadherin
chr16_+_22124870 0.536 NM_013302
EEF2K
eukaryotic elongation factor-2 kinase
chr1_-_224253650 0.536 C1orf55
chromosome 1 open reading frame 55
chr6_-_84994032 0.534 NM_014895
KIAA1009
KIAA1009
chr1_-_210939929 0.533 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr7_-_29995809 0.533 NM_001145515
NM_014766
NM_001145513
SCRN1


secernin 1


chr20_+_43952997 0.533 NM_000308
NM_001127695
NM_001167594
CTSA


cathepsin A


chr1_-_40335510 0.532 PPT1
palmitoyl-protein thioesterase 1
chr1_-_224253610 0.531 C1orf55
chromosome 1 open reading frame 55
chr16_-_1341766 0.529 NM_001001410
C16orf42
chromosome 16 open reading frame 42
chr16_+_80370426 0.527 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr16_-_23429256 0.524 GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr1_-_152459506 0.524 C1orf43
chromosome 1 open reading frame 43
chr12_+_102883687 0.521 NM_003211
TDG
thymine-DNA glycosylase
chr17_+_63252087 0.521 NM_004459
NM_182641
BPTF

bromodomain PHD finger transcription factor

chr14_-_92869113 0.517 BTBD7
BTB (POZ) domain containing 7
chr1_-_224253642 0.515 C1orf55
chromosome 1 open reading frame 55
chr17_-_52346351 0.512 TRIM25
tripartite motif containing 25
chr18_-_45241014 0.512 NM_017653
DYM
dymeclin
chr17_-_71486748 0.511 ACOX1
acyl-CoA oxidase 1, palmitoyl
chr17_+_75851984 0.511


chr20_+_2769338 0.510 NM_022575
NM_080413
VPS16

vacuolar protein sorting 16 homolog (S. cerevisiae)

chr1_-_40335496 0.510 PPT1
palmitoyl-protein thioesterase 1
chr13_+_112999590 0.505 LAMP1
lysosomal-associated membrane protein 1
chr1_-_24024519 0.505 NM_000191
NM_001166059
HMGCL

3-hydroxymethyl-3-methylglutaryl-CoA lyase

chr7_+_97574054 0.504 NM_014916
LMTK2
lemur tyrosine kinase 2
chr1_-_40335504 0.504 PPT1
palmitoyl-protein thioesterase 1
chr2_+_148495043 0.501 NM_018328
MBD5
methyl-CpG binding domain protein 5
chr14_-_23752476 0.499 CHMP4A
chromatin modifying protein 4A
chr1_-_152459667 0.498 C1orf43
chromosome 1 open reading frame 43
chr9_-_133574928 0.498 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr12_-_56432385 0.497 NM_000075
CDK4
cyclin-dependent kinase 4
chr14_-_70345485 0.497 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr19_+_37528340 0.494 NM_001136156
NM_014910
ZNF507

zinc finger protein 507

chr11_+_120399966 0.493 NM_001130047
NM_152715
TBCEL

tubulin folding cofactor E-like

chr3_-_33113580 0.488 GLB1
galactosidase, beta 1
chr12_+_49185035 0.484 DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr12_+_51686512 0.483 EIF4B
eukaryotic translation initiation factor 4B
chr22_-_36907638 0.482 NM_001004426
NM_003560
PLA2G6

phospholipase A2, group VI (cytosolic, calcium-independent)

chr10_-_100196647 0.481 HPS1
Hermansky-Pudlak syndrome 1
chr20_+_33506322 0.481 NM_007186
CEP250
centrosomal protein 250kDa
chr6_+_138230045 0.480 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_+_109963982 0.479 AMPD2
adenosine monophosphate deaminase 2
chr8_+_26296439 0.477 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr9_+_130749812 0.477 NUP188
nucleoporin 188kDa
chr16_-_1464927 0.477 CLCN7
chloride channel 7
chr16_-_23429295 0.476 GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr3_+_160002408 0.472 NM_001167903
NM_022736
MFSD1

major facilitator superfamily domain containing 1

chr16_-_71549149 0.471 ZFHX3
zinc finger homeobox 3
chrX_+_146801142 0.470 NM_001185075
NM_001185076
NM_001185081
NM_001185082
NM_002024
FMR1




fragile X mental retardation 1




chr14_-_91642641 0.469 ATXN3
ATXN8
ataxin 3
ataxin 8
chr20_+_37024383 0.469 NM_001190809
NM_021931
DHX35

DEAH (Asp-Glu-Ala-His) box polypeptide 35

chr17_+_71487080 0.469 C17orf106
chromosome 17 open reading frame 106
chr1_+_10015577 0.468 NM_001105562
NM_006048
UBE4B

ubiquitination factor E4B (UFD2 homolog, yeast)

chr11_+_125586828 0.467 NM_024556
FAM118B
family with sequence similarity 118, member B
chr16_-_5023914 0.466 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr16_-_1465021 0.465 CLCN7
chloride channel 7
chr12_+_110935534 0.465 NM_001034025
NM_006817
ERP29

endoplasmic reticulum protein 29

chr8_-_81246215 0.464 NM_001025253
NM_005079
TPD52

tumor protein D52

chr1_-_152459697 0.462 NM_001098616
NM_015449
NM_138740
C1orf43


chromosome 1 open reading frame 43


chr11_-_85457469 0.462 PICALM
phosphatidylinositol binding clathrin assembly protein
chr16_-_5023562 0.460 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr6_+_87921980 0.459 NM_015021
ZNF292
zinc finger protein 292

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 1.25e-15 GO:0044237 cellular metabolic process
1.28 1.14e-12 GO:0008152 metabolic process
1.30 3.80e-12 GO:0044238 primary metabolic process
1.35 2.57e-09 GO:0044260 cellular macromolecule metabolic process
1.15 2.71e-09 GO:0009987 cellular process
1.42 1.21e-08 GO:0034641 cellular nitrogen compound metabolic process
1.41 1.23e-08 GO:0006807 nitrogen compound metabolic process
1.45 4.98e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 3.98e-07 GO:0043170 macromolecule metabolic process
1.60 1.32e-05 GO:0033036 macromolecule localization
1.40 7.54e-05 GO:0044249 cellular biosynthetic process
1.46 1.10e-04 GO:0010467 gene expression
1.57 1.17e-04 GO:0051641 cellular localization
1.41 1.21e-04 GO:0090304 nucleic acid metabolic process
1.58 3.45e-04 GO:0044248 cellular catabolic process
1.51 3.73e-04 GO:0009056 catabolic process
1.37 3.83e-04 GO:0009058 biosynthetic process
1.70 5.38e-04 GO:0046907 intracellular transport
1.43 6.66e-04 GO:0044281 small molecule metabolic process
1.57 1.45e-03 GO:0008104 protein localization
1.34 2.12e-03 GO:0044267 cellular protein metabolic process
2.37 2.81e-03 GO:0000375 RNA splicing, via transesterification reactions
5.06 3.61e-03 GO:0015682 ferric iron transport
5.06 3.61e-03 GO:0033572 transferrin transport
1.72 4.55e-03 GO:0006396 RNA processing
1.41 4.85e-03 GO:0016070 RNA metabolic process
3.65 5.41e-03 GO:0015992 proton transport
1.27 5.70e-03 GO:0051179 localization
2.88 8.62e-03 GO:0000041 transition metal ion transport
1.51 8.74e-03 GO:0051649 establishment of localization in cell
3.53 8.98e-03 GO:0006818 hydrogen transport
2.30 1.13e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.30 1.13e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
2.01 1.53e-02 GO:0008380 RNA splicing
1.40 1.64e-02 GO:0006996 organelle organization
1.87 2.04e-02 GO:0006397 mRNA processing
1.74 2.35e-02 GO:0034613 cellular protein localization
1.94 2.71e-02 GO:0071495 cellular response to endogenous stimulus
4.64 2.71e-02 GO:0015988 energy coupled proton transport, against electrochemical gradient
4.64 2.71e-02 GO:0015991 ATP hydrolysis coupled proton transport
1.73 2.89e-02 GO:0070727 cellular macromolecule localization
1.27 3.32e-02 GO:0051234 establishment of localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 6.63e-29 GO:0044424 intracellular part
1.31 1.44e-28 GO:0043227 membrane-bounded organelle
1.21 1.96e-28 GO:0005622 intracellular
1.31 3.45e-28 GO:0043231 intracellular membrane-bounded organelle
1.27 1.89e-26 GO:0043226 organelle
1.27 6.23e-26 GO:0043229 intracellular organelle
1.30 1.25e-23 GO:0005737 cytoplasm
1.40 4.55e-23 GO:0044444 cytoplasmic part
1.42 3.31e-22 GO:0044446 intracellular organelle part
1.42 8.16e-22 GO:0044422 organelle part
1.67 8.33e-17 GO:0031974 membrane-enclosed lumen
1.66 2.35e-16 GO:0043233 organelle lumen
1.66 8.10e-16 GO:0070013 intracellular organelle lumen
1.65 5.37e-14 GO:0005829 cytosol
2.91 6.85e-14 GO:0005773 vacuole
1.61 7.29e-13 GO:0044428 nuclear part
1.64 1.25e-11 GO:0031981 nuclear lumen
1.78 1.50e-11 GO:0005654 nucleoplasm
2.90 1.86e-11 GO:0000323 lytic vacuole
2.90 1.86e-11 GO:0005764 lysosome
1.29 2.61e-10 GO:0005634 nucleus
1.40 4.35e-10 GO:0032991 macromolecular complex
3.14 4.08e-08 GO:0044437 vacuolar part
3.12 1.53e-07 GO:0005774 vacuolar membrane
1.38 3.69e-07 GO:0043234 protein complex
1.58 2.50e-06 GO:0005739 mitochondrion
2.06 2.63e-06 GO:0005768 endosome
1.06 3.30e-06 GO:0044464 cell part
1.06 3.42e-06 GO:0005623 cell
3.19 7.17e-06 GO:0005765 lysosomal membrane
1.74 4.09e-05 GO:0044451 nucleoplasm part
1.74 4.38e-05 GO:0031967 organelle envelope
1.76 4.42e-05 GO:0044429 mitochondrial part
1.71 9.90e-05 GO:0031975 envelope
1.38 1.31e-04 GO:0031090 organelle membrane
4.41 2.38e-04 GO:0016469 proton-transporting two-sector ATPase complex
6.33 3.84e-04 GO:0033176 proton-transporting V-type ATPase complex
3.13 5.47e-04 GO:0042470 melanosome
3.13 5.47e-04 GO:0048770 pigment granule
2.24 7.41e-04 GO:0016604 nuclear body
1.80 1.60e-03 GO:0005740 mitochondrial envelope
2.70 1.88e-03 GO:0005770 late endosome
3.61 2.05e-03 GO:0016605 PML body
1.79 3.15e-03 GO:0031966 mitochondrial membrane
1.73 3.67e-03 GO:0030529 ribonucleoprotein complex
2.37 1.01e-02 GO:0005769 early endosome
1.26 2.25e-02 GO:0043228 non-membrane-bounded organelle
1.26 2.25e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.51 2.56e-02 GO:0031982 vesicle
9.04 2.58e-02 GO:0031082 BLOC complex
9.04 2.58e-02 GO:0031083 BLOC-1 complex
1.94 3.05e-02 GO:0010008 endosome membrane
1.79 3.43e-02 GO:0019866 organelle inner membrane
1.51 3.59e-02 GO:0031410 cytoplasmic vesicle
1.92 3.64e-02 GO:0044440 endosomal part
1.52 3.74e-02 GO:0031988 membrane-bounded vesicle
1.64 4.08e-02 GO:0005730 nucleolus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.27 3.23e-13 GO:0005515 protein binding
1.12 6.15e-08 GO:0005488 binding
1.38 6.11e-05 GO:0000166 nucleotide binding
1.67 1.28e-04 GO:0003723 RNA binding
1.21 3.16e-04 GO:0003824 catalytic activity
1.37 2.95e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.35 5.42e-03 GO:0017076 purine nucleotide binding
1.35 8.24e-03 GO:0032553 ribonucleotide binding
1.35 8.24e-03 GO:0032555 purine ribonucleotide binding
5.62 2.13e-02 GO:0046961 proton-transporting ATPase activity, rotational mechanism
4.22 4.29e-02 GO:0019829 cation-transporting ATPase activity