Motif ID: SPI1.p2

Z-value: 3.614


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_473565620.581.8e-02Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_35586950 3.341 NM_000631
NM_013416
 NCF4

neutrophil cytosolic factor 4, 40kDa

chr5_-_88215034 3.070 NM_001193350
NM_002397
 MEF2C

myocyte enhancer factor 2C

chr1_+_111544469 2.850


chr1_+_159899528 2.712 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
 FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chrX_+_134482212 2.398 NM_182540
 DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr10_+_49562866 2.229 WDFY4
WDFY family member 4
chr9_+_263025 2.110 NM_001190458
NM_001193536
 DOCK8

dedicator of cytokinesis 8

chr1_-_31003260 2.102 NM_006762
 LAPTM5
lysosomal protein transmembrane 5
chrX_-_134883798 2.027 NM_173470
 MMGT1
membrane magnesium transporter 1
chrX_+_72699834 2.007 CHIC1
cysteine-rich hydrophobic domain 1
chr5_-_88214720 1.959 MEF2C
myocyte enhancer factor 2C
chr16_-_87570716 1.953 NM_005187
 CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chrX_+_134482387 1.904 DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_+_25096755 1.901 LRMP
lymphoid-restricted membrane protein
chr11_+_107304344 1.875 NM_017516
 RAB39
RAB39, member RAS oncogene family
chr10_+_26767698 1.843 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr11_+_63864263 1.715 NM_032251
 CCDC88B
coiled-coil domain containing 88B
chr4_-_25473528 1.698 NM_015187
 SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr3_-_113334657 1.578 NM_001190259
NM_001190260
NM_152785
 GCET2


germinal center expressed transcript 2


chrX_-_47374187 1.573 NM_001145252
 CFP
complement factor properdin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 54 entries
enrichment   p-value GO term description
2.26 1.96e-02 GO:0002285 lymphocyte activation involved in immune response
2.03 1.60e-02 GO:0002263 cell activation involved in immune response
2.03 1.60e-02 GO:0002366 leukocyte activation involved in immune response
1.75 6.00e-03 GO:0030098 lymphocyte differentiation
1.51 1.41e-02 GO:0046649 lymphocyte activation
1.50 2.13e-04 GO:0032446 protein modification by small protein conjugation
1.50 1.47e-03 GO:0045321 leukocyte activation
1.46 5.96e-03 GO:0016567 protein ubiquitination
1.45 3.06e-04 GO:0070647 protein modification by small protein conjugation or removal
1.43 1.94e-06 GO:0001775 cell activation
1.38 6.60e-05 GO:0016071 mRNA metabolic process
1.38 1.80e-04 GO:0007599 hemostasis
1.37 4.92e-04 GO:0007596 blood coagulation
1.37 4.92e-04 GO:0050817 coagulation
1.37 9.34e-03 GO:0006397 mRNA processing
1.34 1.77e-03 GO:0044265 cellular macromolecule catabolic process
1.32 1.16e-02 GO:0006974 response to DNA damage stimulus
1.31 1.15e-03 GO:0006396 RNA processing
1.31 4.92e-03 GO:0042060 wound healing
1.31 5.06e-03 GO:0050878 regulation of body fluid levels

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
1.45 2.32e-02 GO:0030425 dendrite
1.43 1.20e-02 GO:0016604 nuclear body
1.24 1.11e-02 GO:0044451 nucleoplasm part
1.23 1.91e-05 GO:0005654 nucleoplasm
1.19 1.45e-06 GO:0044428 nuclear part
1.19 1.94e-05 GO:0031981 nuclear lumen
1.18 1.46e-05 GO:0005829 cytosol
1.15 8.46e-06 GO:0043234 protein complex
1.13 1.67e-05 GO:0032991 macromolecular complex
1.12 2.60e-02 GO:0031974 membrane-enclosed lumen
1.12 2.75e-02 GO:0043233 organelle lumen
1.12 4.08e-02 GO:0070013 intracellular organelle lumen
1.11 2.27e-08 GO:0005634 nucleus
1.09 3.87e-04 GO:0044446 intracellular organelle part
1.08 7.41e-09 GO:0005737 cytoplasm
1.08 1.20e-03 GO:0044422 organelle part
1.07 1.53e-11 GO:0044424 intracellular part
1.07 1.52e-06 GO:0043227 membrane-bounded organelle
1.07 1.56e-06 GO:0043231 intracellular membrane-bounded organelle
1.07 7.15e-03 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.54 6.25e-03 GO:0004721 phosphoprotein phosphatase activity
1.49 8.10e-04 GO:0019787 small conjugating protein ligase activity
1.48 2.93e-03 GO:0004842 ubiquitin-protein ligase activity
1.44 2.06e-03 GO:0016881 acid-amino acid ligase activity
1.37 2.06e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.11 1.51e-12 GO:0005515 protein binding
1.04 6.28e-05 GO:0005488 binding