Motif ID: SPI1.p2

Z-value: 3.614


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_473565620.581.8e-02Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_35586950 3.341 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr5_-_88215034 3.070 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr1_+_111544469 2.850


chr1_+_159899528 2.712 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chrX_+_134482212 2.398 NM_182540
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr10_+_49562866 2.229 WDFY4
WDFY family member 4
chr9_+_263025 2.110 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr1_-_31003260 2.102 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chrX_-_134883798 2.027 NM_173470
MMGT1
membrane magnesium transporter 1
chrX_+_72699834 2.007 CHIC1
cysteine-rich hydrophobic domain 1
chr5_-_88214720 1.959 MEF2C
myocyte enhancer factor 2C
chr16_-_87570716 1.953 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chrX_+_134482387 1.904 DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_+_25096755 1.901 LRMP
lymphoid-restricted membrane protein
chr11_+_107304344 1.875 NM_017516
RAB39
RAB39, member RAS oncogene family
chr10_+_26767698 1.843 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr11_+_63864263 1.715 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr4_-_25473528 1.698 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr3_-_113334657 1.578 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chrX_-_47374187 1.573 NM_001145252
CFP
complement factor properdin
chr19_-_43800374 1.566 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr22_-_35970230 1.546 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_+_159817752 1.498 NM_201563
FCGR2C
Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr5_+_118719591 1.477 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr16_-_29664765 1.472 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr2_+_227737524 1.469 NM_000091
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr1_-_31003181 1.450 LAPTM5
lysosomal protein transmembrane 5
chr10_+_70553993 1.444 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr8_-_11096257 1.439 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr12_+_25096472 1.422 NM_006152
LRMP
lymphoid-restricted membrane protein
chr11_+_122936145 1.420 GRAMD1B
GRAM domain containing 1B
chr6_+_76051433 1.382 LOC100506804
hypothetical LOC100506804
chr7_+_21434097 1.369 NM_003112
SP4
Sp4 transcription factor
chr7_+_106292975 1.368 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr10_-_7493418 1.359 NM_001029880
SFMBT2
Scm-like with four mbt domains 2
chr12_-_50004172 1.345 NM_016293
BIN2
bridging integrator 2
chr5_-_137117936 1.322 NM_006805
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr3_+_145173329 1.312 NM_173552
C3orf58
chromosome 3 open reading frame 58
chr10_+_26767657 1.309 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr2_-_197883569 1.307 ANKRD44
ankyrin repeat domain 44
chr5_+_176493752 1.305 NSD1
nuclear receptor binding SET domain protein 1
chr6_+_31651319 1.302 NM_000594
TNF
tumor necrosis factor
chrX_-_17789276 1.290 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr16_+_56134077 1.288 NM_153837
GPR114
G protein-coupled receptor 114
chr7_-_3049872 1.276 NM_032415
CARD11
caspase recruitment domain family, member 11
chrX_-_83644054 1.266 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr22_-_35970133 1.265 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr10_-_27189898 1.248 ABI1
abl-interactor 1
chr3_+_120495906 1.243 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr1_-_111544784 1.240 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr16_+_29582069 1.237 NM_003123
SPN
sialophorin
chrX_-_74062005 1.237 NM_001008537
KIAA2022
KIAA2022
chr7_+_106292932 1.224 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr10_+_26767288 1.219 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr16_+_56134037 1.217 GPR114
G protein-coupled receptor 114
chr7_+_114350144 1.211 MDFIC
MyoD family inhibitor domain containing
chr17_+_44643067 1.211 ABI3
ABI family, member 3
chr17_+_44642587 1.186 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr1_-_183210155 1.174 FAM129A
family with sequence similarity 129, member A
chr19_-_7672978 1.170 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr1_-_111544820 1.163 DENND2D
DENN/MADD domain containing 2D
chr2_-_182229977 1.150 NM_001030311
NM_001030312
NM_001030313
NM_001160277
NM_201548
CERKL




ceramide kinase-like




chrX_-_153632355 1.128 NM_001081573
NM_080612
GAB3

GRB2-associated binding protein 3

chr2_+_68445821 1.128 NM_002664
PLEK
pleckstrin
chr11_+_122936246 1.118 GRAMD1B
GRAM domain containing 1B
chr1_+_234372454 1.118 NM_003272
GPR137B
G protein-coupled receptor 137B
chr9_+_34643911 1.104 NM_004512
NM_147162
IL11RA

interleukin 11 receptor, alpha

chr1_-_183210296 1.098 NM_052966
FAM129A
family with sequence similarity 129, member A
chr2_-_231498184 1.096 NM_005683
GPR55
G protein-coupled receptor 55
chr8_+_56954899 1.089 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr22_-_36212160 1.086 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr10_-_98021144 1.086 NM_001114094
NM_013314
BLNK

B-cell linker

chr21_+_25856311 1.073 MIR155HG
MIR155 host gene (non-protein coding)
chr6_+_31661934 1.073 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr1_+_26517032 1.071 CD52
CD52 molecule
chr3_-_196644864 1.066 NM_012287
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr8_+_56954946 1.044 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr17_-_8809656 1.043 NM_001142633
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr11_-_66877519 1.036 NM_021173
POLD4
polymerase (DNA-directed), delta 4
chr12_-_51887266 1.033 NM_000889
ITGB7
integrin, beta 7
chr11_-_74120077 1.032 CHRDL2
chordin-like 2
chr11_+_66927955 1.026 TBC1D10C
TBC1 domain family, member 10C
chrX_-_44945025 1.024 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr1_+_26517045 1.023 CD52
CD52 molecule
chr6_-_33016561 1.017 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr17_+_40655060 1.012 NM_005892
FMNL1
formin-like 1
chr14_-_47213906 1.009 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr1_-_181871473 1.008 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr18_-_50004770 0.996 MBD2
methyl-CpG binding domain protein 2
chr1_+_26609893 0.996 LIN28A
lin-28 homolog A (C. elegans)
chr5_+_177473071 0.970 NM_015111
N4BP3
NEDD4 binding protein 3
chr10_-_27189995 0.969 NM_001012750
NM_001012751
NM_001012752
NM_001178116
NM_001178119
NM_001178120
NM_001178121
NM_001178122
NM_001178123
NM_001178124
NM_001178125
NM_005470
ABI1











abl-interactor 1











chr10_-_27189797 0.958 ABI1
abl-interactor 1
chr5_+_129268352 0.956 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr16_+_29582065 0.947 SPN
sialophorin
chr10_-_31647925 0.946 LOC220930
hypothetical LOC220930
chr1_-_208024491 0.946 NM_152485
C1orf74
chromosome 1 open reading frame 74
chr1_-_159306037 0.945 ARHGAP30
Rho GTPase activating protein 30
chr12_+_53177806 0.942 NCKAP1L
NCK-associated protein 1-like
chr1_-_181826292 0.940 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr18_-_51406841 0.931 NM_001083962
NM_003199
TCF4

transcription factor 4

chr1_+_111217244 0.929 NM_000560
CD53
CD53 molecule
chrX_-_48713194 0.926 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr12_-_50004208 0.924 BIN2
bridging integrator 2
chr1_-_21375939 0.923 NM_001198801
NM_001198802
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr5_+_49998528 0.919 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr17_-_55824083 0.913 USP32
ubiquitin specific peptidase 32
chr1_-_181871490 0.912 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr17_+_26060617 0.906


chr22_-_35938298 0.905 NM_001051
SSTR3
somatostatin receptor 3
chrX_-_14801077 0.904 NM_001018113
NM_152633
FANCB

Fanconi anemia, complementation group B

chr8_-_9045548 0.902 NM_024607
PPP1R3B
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chrX_-_118711144 0.901 SEPT6
septin 6
chr1_-_222688623 0.900 NM_001115113
NM_025160
WDR26

WD repeat domain 26

chr2_+_79593679 0.900 CTNNA2
catenin (cadherin-associated protein), alpha 2
chr1_-_17318452 0.898 NM_007365
PADI2
peptidyl arginine deiminase, type II
chrX_-_13745134 0.891 GPM6B
glycoprotein M6B
chr2_-_60634271 0.891 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr6_+_31648071 0.889 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr4_+_82171142 0.887 NM_001201
BMP3
bone morphogenetic protein 3
chr7_+_73826244 0.876 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chrX_+_117513899 0.873 NM_144658
DOCK11
dedicator of cytokinesis 11
chr12_+_53177758 0.873 NM_005337
NCKAP1L
NCK-associated protein 1-like
chr8_+_56954953 0.871 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_159306327 0.871 ARHGAP30
Rho GTPase activating protein 30
chrX_-_78509367 0.869 ITM2A
integral membrane protein 2A
chr12_+_53177789 0.864 NCKAP1L
NCK-associated protein 1-like
chr11_+_128068982 0.862 NM_002017
FLI1
Friend leukemia virus integration 1
chr1_+_26671488 0.855 NM_005517
HMGN2
high-mobility group nucleosomal binding domain 2
chr10_-_121292139 0.854 NM_001005339
RGS10
regulator of G-protein signaling 10
chr6_+_31647854 0.853 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr3_+_213535 0.851 NM_006614
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr3_+_197851052 0.848 NM_198565
LRRC33
leucine rich repeat containing 33
chr5_+_49998677 0.847 PARP8
poly (ADP-ribose) polymerase family, member 8
chr1_+_32512298 0.844 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr12_+_60940404 0.843 NM_006313
USP15
ubiquitin specific peptidase 15
chr14_-_98807574 0.843 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr6_-_32268267 0.842 GPSM3
G-protein signaling modulator 3
chr3_-_15348811 0.840 SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr7_-_37454933 0.840 NM_014800
ELMO1
engulfment and cell motility 1
chr2_+_85051942 0.833 KCMF1
potassium channel modulatory factor 1
chr3_-_120861959 0.833 NM_022135
POPDC2
popeye domain containing 2
chr1_+_172395277 0.832 RABGAP1L
RAB GTPase activating protein 1-like
chr1_+_111217314 0.832 CD53
CD53 molecule
chrX_+_48427103 0.825 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr12_-_50004102 0.822 BIN2
bridging integrator 2
chr13_-_45654292 0.821 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_132095496 0.819 ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr10_+_70745615 0.814 NM_033496
HK1
hexokinase 1
chrX_-_153698930 0.814 HMGN1P37
high-mobility group nucleosome binding domain 1 pseudogene 37
chrX_+_48427137 0.812 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr17_-_31441390 0.809 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr18_-_59137488 0.807 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr3_+_145173585 0.806 C3orf58
chromosome 3 open reading frame 58
chr9_-_91302707 0.805 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr1_+_26609819 0.804 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr1_-_181871462 0.800 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr10_+_71908535 0.796 NM_014431
KIAA1274
KIAA1274
chr7_-_120285364 0.795 NM_012338
TSPAN12
tetraspanin 12
chr19_-_15436333 0.794 NM_022904
RASAL3
RAS protein activator like 3
chr10_+_70748633 0.792 HK1
hexokinase 1
chr10_+_26767268 0.787 NM_019043
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr19_-_10311262 0.787 NM_002162
ICAM3
intercellular adhesion molecule 3
chr2_+_143603368 0.782 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr3_+_19963534 0.782 NM_004162
RAB5A
RAB5A, member RAS oncogene family
chr7_+_106293112 0.781 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr4_-_84475023 0.781 HPSE
heparanase
chr18_-_27518392 0.779 NM_004775
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr1_+_158387975 0.779 NM_144699
ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr12_+_6930815 0.778 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr17_-_26665144 0.777 EVI2B
ecotropic viral integration site 2B
chr9_+_130491668 0.773 SET
SET nuclear oncogene
chr15_+_79304694 0.769 NM_172217
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr7_+_128651976 0.769 NM_001130720
NM_015328
AHCYL2

adenosylhomocysteinase-like 2

chr20_+_42947754 0.769 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr10_+_129735796 0.768 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr5_+_176493233 0.764 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr9_+_92604025 0.763 NM_001174168
SYK
spleen tyrosine kinase
chr5_+_176493488 0.761 NSD1
nuclear receptor binding SET domain protein 1
chr16_+_28413421 0.759 NM_018690
APOBR
apolipoprotein B receptor
chr19_-_59418739 0.756 NM_001081450
NM_006864
LILRB3

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3

chr7_-_44985084 0.756 MYO1G
myosin IG
chr3_-_122862447 0.755 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr12_+_70343943 0.752 NM_031435
THAP2
THAP domain containing, apoptosis associated protein 2
chr2_+_85051687 0.752 NM_020122
KCMF1
potassium channel modulatory factor 1
chr12_+_119418294 0.750 DYNLL1
dynein, light chain, LC8-type 1
chrX_-_153952447 0.750 NM_001018024
NM_001018025
MTCP1NB
MTCP1
mature T-cell proliferation 1 neighbor
mature T-cell proliferation 1
chr17_-_26665213 0.749 EVI2B
ecotropic viral integration site 2B
chr11_+_122901543 0.748 GRAMD1B
GRAM domain containing 1B
chr9_-_129580732 0.747 NM_170600
SH2D3C
SH2 domain containing 3C
chr22_+_35639564 0.746 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_+_89871281 0.746 LRRC8C
leucine rich repeat containing 8 family, member C
chr9_+_70509925 0.746 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr1_-_181826086 0.745 NCF2
neutrophil cytosolic factor 2
chr1_+_149309703 0.743 NM_144618
GABPB2
GA binding protein transcription factor, beta subunit 2
chr7_+_101715137 0.740 SH2B2
SH2B adaptor protein 2
chr1_+_185064654 0.739 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr1_-_158883666 0.737 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr22_+_30072739 0.737 FLJ20464
hypothetical protein FLJ20464
chr2_+_68445936 0.736 PLEK
pleckstrin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.18 1.30e-14 GO:0044260 cellular macromolecule metabolic process
1.15 1.48e-11 GO:0043170 macromolecule metabolic process
1.07 1.14e-10 GO:0009987 cellular process
1.10 1.73e-07 GO:0050794 regulation of cellular process
1.09 2.24e-07 GO:0065007 biological regulation
1.19 4.24e-07 GO:0044267 cellular protein metabolic process
1.20 5.64e-07 GO:0090304 nucleic acid metabolic process
1.10 6.11e-07 GO:0044237 cellular metabolic process
1.09 7.29e-07 GO:0050789 regulation of biological process
1.10 9.34e-07 GO:0044238 primary metabolic process
1.43 1.94e-06 GO:0001775 cell activation
1.17 2.47e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 8.94e-06 GO:0016070 RNA metabolic process
1.20 3.81e-05 GO:0006464 protein modification process
1.38 6.60e-05 GO:0016071 mRNA metabolic process
1.24 1.42e-04 GO:0002376 immune system process
1.14 1.69e-04 GO:0019538 protein metabolic process
1.38 1.80e-04 GO:0007599 hemostasis
1.50 2.13e-04 GO:0032446 protein modification by small protein conjugation
1.16 2.90e-04 GO:0006950 response to stress
1.12 2.96e-04 GO:0051716 cellular response to stimulus
1.45 3.06e-04 GO:0070647 protein modification by small protein conjugation or removal
1.37 4.92e-04 GO:0007596 blood coagulation
1.37 4.92e-04 GO:0050817 coagulation
1.08 6.69e-04 GO:0008152 metabolic process
1.18 6.83e-04 GO:0043412 macromolecule modification
1.31 1.15e-03 GO:0006396 RNA processing
1.50 1.47e-03 GO:0045321 leukocyte activation
1.34 1.77e-03 GO:0044265 cellular macromolecule catabolic process
1.13 2.23e-03 GO:0034641 cellular nitrogen compound metabolic process
1.18 3.90e-03 GO:0006996 organelle organization
1.11 4.10e-03 GO:0023052 signaling
1.31 4.92e-03 GO:0042060 wound healing
1.31 5.06e-03 GO:0050878 regulation of body fluid levels
1.12 5.36e-03 GO:0006807 nitrogen compound metabolic process
1.46 5.96e-03 GO:0016567 protein ubiquitination
1.75 6.00e-03 GO:0030098 lymphocyte differentiation
1.12 6.14e-03 GO:0007165 signal transduction
1.37 9.34e-03 GO:0006397 mRNA processing
1.29 9.96e-03 GO:0051726 regulation of cell cycle
1.32 1.16e-02 GO:0006974 response to DNA damage stimulus
1.29 1.17e-02 GO:0009057 macromolecule catabolic process
1.13 1.34e-02 GO:0071842 cellular component organization at cellular level
1.22 1.38e-02 GO:0032268 regulation of cellular protein metabolic process
1.51 1.41e-02 GO:0046649 lymphocyte activation
1.11 1.49e-02 GO:0016043 cellular component organization
2.03 1.60e-02 GO:0002263 cell activation involved in immune response
2.03 1.60e-02 GO:0002366 leukocyte activation involved in immune response
1.17 1.87e-02 GO:0023051 regulation of signaling
2.26 1.96e-02 GO:0002285 lymphocyte activation involved in immune response
1.11 2.79e-02 GO:0071840 cellular component organization or biogenesis
1.21 3.51e-02 GO:0006793 phosphorus metabolic process
1.21 3.51e-02 GO:0006796 phosphate metabolic process
1.13 3.95e-02 GO:0048522 positive regulation of cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 8.29e-12 GO:0005622 intracellular
1.07 1.53e-11 GO:0044424 intracellular part
1.08 7.41e-09 GO:0005737 cytoplasm
1.11 2.27e-08 GO:0005634 nucleus
1.03 8.02e-07 GO:0044464 cell part
1.03 8.78e-07 GO:0005623 cell
1.19 1.45e-06 GO:0044428 nuclear part
1.07 1.52e-06 GO:0043227 membrane-bounded organelle
1.07 1.56e-06 GO:0043231 intracellular membrane-bounded organelle
1.06 7.29e-06 GO:0043229 intracellular organelle
1.06 7.39e-06 GO:0043226 organelle
1.15 8.46e-06 GO:0043234 protein complex
1.18 1.46e-05 GO:0005829 cytosol
1.13 1.67e-05 GO:0032991 macromolecular complex
1.23 1.91e-05 GO:0005654 nucleoplasm
1.19 1.94e-05 GO:0031981 nuclear lumen
1.09 3.87e-04 GO:0044446 intracellular organelle part
1.08 1.20e-03 GO:0044422 organelle part
1.07 7.15e-03 GO:0044444 cytoplasmic part
1.24 1.11e-02 GO:0044451 nucleoplasm part
1.43 1.20e-02 GO:0016604 nuclear body
1.45 2.32e-02 GO:0030425 dendrite
1.12 2.60e-02 GO:0031974 membrane-enclosed lumen
1.12 2.75e-02 GO:0043233 organelle lumen
1.12 4.08e-02 GO:0070013 intracellular organelle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 1.51e-12 GO:0005515 protein binding
1.04 6.28e-05 GO:0005488 binding
1.49 8.10e-04 GO:0019787 small conjugating protein ligase activity
1.44 2.06e-03 GO:0016881 acid-amino acid ligase activity
1.48 2.93e-03 GO:0004842 ubiquitin-protein ligase activity
1.54 6.25e-03 GO:0004721 phosphoprotein phosphatase activity
1.37 2.06e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds