Motif ID: NKX6-1,2.p2

Z-value: 0.996


Transcription factors associated with NKX6-1,2.p2:

Gene SymbolEntrez IDGene Name
NKX6-1 4825 NK6 homeobox 1
NKX6-2 84504 NK6 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX6-2chr10_-_134449467-0.302.7e-01Click!
NKX6-1chr4_-_85638410-0.273.2e-01Click!


Activity profile for motif NKX6-1,2.p2.

activity profile for motif NKX6-1,2.p2


Sorted Z-values histogram for motif NKX6-1,2.p2

Sorted Z-values for motif NKX6-1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX6-1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_169654742 2.057 NM_001166108
NM_016081
 PALLD

palladin, cytoskeletal associated protein

chr2_-_160764819 1.917 NM_000888
 ITGB6
integrin, beta 6
chr2_-_160765008 1.384 ITGB6
integrin, beta 6
chr5_+_166644420 1.267 NM_001122679
 ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr3_-_64186151 1.233 NM_198859
 PRICKLE2
prickle homolog 2 (Drosophila)
chr2_-_151052391 1.153 NM_005168
 RND3
Rho family GTPase 3
chr7_-_41709191 1.147 NM_002192
 INHBA
inhibin, beta A
chr4_-_90978469 1.047 NM_001146055
 SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chrX_-_10495476 1.033 NM_001193278
NM_001193279
NM_001193280
NM_001193281
 MID1



midline 1 (Opitz/BBB syndrome)



chr2_-_237987579 0.907 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
 COL6A3




collagen, type VI, alpha 3




chr12_+_32546243 0.899 NM_139241
 FGD4
FYVE, RhoGEF and PH domain containing 4
chr17_+_58440629 0.860 NM_025185
 TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr2_-_237987554 0.853 COL6A3
collagen, type VI, alpha 3
chr20_+_19863716 0.831 RIN2
Ras and Rab interactor 2
chr8_-_122722674 0.827 NM_005328
 HAS2
hyaluronan synthase 2
chr5_-_58331515 0.778 NM_001197223
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_177427252 0.712 NM_080874
 ASB5
ankyrin repeat and SOCS box containing 5
chr2_-_237987545 0.710 COL6A3
collagen, type VI, alpha 3
chr17_+_58625086 0.700 TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr7_+_28692122 0.693 NM_001011666
 CREB5
cAMP responsive element binding protein 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
6.12 1.88e-02 GO:0050886 endocrine process
1.68 4.97e-02 GO:0048584 positive regulation of response to stimulus
1.48 4.43e-03 GO:0048583 regulation of response to stimulus
1.45 4.69e-02 GO:0003008 system process
1.33 4.57e-02 GO:0048731 system development
1.24 1.47e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.76 4.62e-02 GO:0044420 extracellular matrix part
1.66 7.52e-04 GO:0044421 extracellular region part
1.27 3.38e-03 GO:0005886 plasma membrane
1.26 3.77e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.70 3.07e-02 GO:0005509 calcium ion binding