Motif ID: YY1.p2

Z-value: 2.195


Transcription factors associated with YY1.p2:

Gene SymbolEntrez IDGene Name
YY1 7528 YY1 transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
YY1chr14_+_997748540.068.3e-01Click!


Activity profile for motif YY1.p2.

activity profile for motif YY1.p2


Sorted Z-values histogram for motif YY1.p2

Sorted Z-values for motif YY1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of YY1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_149119029 3.743 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr2_+_149118791 3.294 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr6_-_74284522 3.189 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr2_+_177965734 2.946 AGPS
alkylglycerone phosphate synthase
chr14_-_22574193 2.834 NM_001144932
NM_002797
NM_001130725
PSMB5


proteasome (prosome, macropain) subunit, beta type, 5


chr9_+_114376709 2.747 KIAA1958
KIAA1958
chr20_-_33706532 2.644 RBM12
RNA binding motif protein 12
chr12_+_100615530 2.514 NM_020244
CHPT1
choline phosphotransferase 1
chr6_+_43373986 2.492 SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr20_-_33793507 2.489 RBM39
RNA binding motif protein 39
chr1_-_209818576 2.447 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr11_-_57643491 2.329 NM_001005211
OR9I1
olfactory receptor, family 9, subfamily I, member 1
chr20_-_45418818 2.262 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr6_+_33047952 2.250 BRD2
bromodomain containing 2
chr20_-_49612574 2.109 NM_001136021
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr1_-_209818675 2.107 NM_021194
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr16_+_74239135 2.097 NM_018975
TERF2IP
telomeric repeat binding factor 2, interacting protein
chr9_-_124329392 2.031 NM_012363
OR1N1
olfactory receptor, family 1, subfamily N, member 1
chr1_-_218168137 2.009 SLC30A10
solute carrier family 30, member 10
chr20_-_48980858 1.978 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr3_+_31549123 1.974 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr14_-_22573764 1.951 PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr3_+_31549435 1.895 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr8_+_125556374 1.885 RNF139
ring finger protein 139
chr1_-_218168404 1.840


chr11_+_113815317 1.839 NM_015523
REXO2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr17_+_56032385 1.831 PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr17_+_23393744 1.826 NM_016231
NLK
nemo-like kinase
chr15_+_91244563 1.822 CHD2
chromodomain helicase DNA binding protein 2
chr1_+_42920683 1.818 YBX1
Y box binding protein 1
chr1_-_218168548 1.791 NM_018713
SLC30A10
solute carrier family 30, member 10
chr5_+_139856688 1.773 ANKHD1
ankyrin repeat and KH domain containing 1
chr20_+_30160952 1.772 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr1_+_229181417 1.760 NM_022786
ARV1
ARV1 homolog (S. cerevisiae)
chr11_+_5399916 1.725 NM_001004757
OR51Q1
olfactory receptor, family 51, subfamily Q, member 1
chr3_+_31549478 1.714 NM_178862
STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chrX_-_62487693 1.701 NM_001012968
SPIN4
spindlin family, member 4
chr16_-_19440786 1.695 NM_016641
GDE1
glycerophosphodiester phosphodiesterase 1
chr20_+_36988368 1.681 NM_030919
FAM83D
family with sequence similarity 83, member D
chr2_-_177965626 1.672 LOC100130691
hypothetical LOC100130691
chr15_-_75259714 1.665 PEAK1
NKF3 kinase family member
chr2_+_43919606 1.658 NM_022437
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr20_-_49612745 1.655 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr1_+_159462456 1.652 NM_032174
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr17_-_46479127 1.648 SPAG9
sperm associated antigen 9
chr1_+_166172679 1.641 DCAF6
DDB1 and CUL4 associated factor 6
chr2_+_177965617 1.640 NM_003659
AGPS
alkylglycerone phosphate synthase
chr1_+_166172545 1.637 DCAF6
DDB1 and CUL4 associated factor 6
chr6_+_32003380 1.627 C2
complement component 2
chr8_+_97343313 1.619 PTDSS1
phosphatidylserine synthase 1
chr1_+_166172420 1.613 NM_001017977
NM_001198956
NM_001198957
NM_018442
DCAF6



DDB1 and CUL4 associated factor 6



chr17_-_2943039 1.595 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr3_+_142939827 1.571 RNF7
ring finger protein 7
chr19_+_5574088 1.553 SAFB
scaffold attachment factor B
chr16_-_29532538 1.545


chr5_-_178977441 1.545 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr12_-_48246488 1.541 NM_001012300
MCRS1
microspherule protein 1
chr1_+_26973804 1.533 ARID1A
AT rich interactive domain 1A (SWI-like)
chr10_+_104995633 1.531 NM_001143909
LOC729020
rcRPE
chr20_+_30161173 1.529 TM9SF4
transmembrane 9 superfamily protein member 4
chr8_+_97343334 1.517 NM_014754
PTDSS1
phosphatidylserine synthase 1
chr8_+_125556294 1.513 RNF139
ring finger protein 139
chr15_+_91244422 1.506 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr15_-_35179185 1.500 MEIS2
Meis homeobox 2
chr8_-_55097237 1.492 TCEA1
transcription elongation factor A (SII), 1
chr11_+_14621972 1.491 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chrX_-_71850434 1.490 NM_001122670
NM_001172436
NM_002637
PHKA1


phosphorylase kinase, alpha 1 (muscle)


chr7_+_104441730 1.479 NM_018682
NM_182931
MLL5

myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

chr1_+_146910634 1.479 NM_001144032
PPIAL4E
peptidylprolyl isomerase A (cyclophilin A)-like 4E
chr9_-_106420305 1.476 NM_001001956
OR13C9
olfactory receptor, family 13, subfamily C, member 9
chr6_+_33276580 1.469 NM_001077516
NM_006979
SLC39A7

solute carrier family 39 (zinc transporter), member 7

chr17_+_68700792 1.464 COG1
component of oligomeric golgi complex 1
chr11_+_5431213 1.463 NM_001004754
OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr1_-_198644111 1.455 ZNF281
zinc finger protein 281
chr15_+_48261649 1.454 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr19_+_39355254 1.454 LSM14A
LSM14A, SCD6 homolog A (S. cerevisiae)
chr1_+_159986164 1.450 NM_007240
DUSP12
dual specificity phosphatase 12
chr5_-_180603335 1.448 GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr5_-_158567411 1.437 NM_144726
RNF145
ring finger protein 145
chr8_+_23442307 1.417 NM_016612
SLC25A37
solute carrier family 25, member 37
chr17_+_55052185 1.415


chr1_+_201243136 1.413 TMEM183A
transmembrane protein 183A
chr1_+_172683834 1.413 NM_005684
GPR52
G protein-coupled receptor 52
chr10_+_79463624 1.398 RPS24
ribosomal protein S24
chr6_+_135544214 1.393 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr12_-_111304138 1.388 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chr1_+_51208499 1.388 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr11_-_129377889 1.380 PRDM10
PR domain containing 10
chr14_-_30565275 1.366 NM_001083893
NM_014574
STRN3

striatin, calmodulin binding protein 3

chr17_-_72244231 1.366


chr19_-_44014228 1.364 NM_001398
ECH1
enoyl CoA hydratase 1, peroxisomal
chr14_-_22468445 1.360 NM_001039619
NM_006109
PRMT5

protein arginine methyltransferase 5

chr2_-_171725150 1.356 TLK1
tousled-like kinase 1
chr1_-_152431175 1.353 NM_152263
TPM3
tropomyosin 3
chr2_+_32435550 1.347 NM_016252
BIRC6
baculoviral IAP repeat containing 6
chr19_-_52307642 1.344


chr2_+_32435800 1.339 BIRC6
baculoviral IAP repeat containing 6
chr17_+_34114924 1.334 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr1_+_46541913 1.325 NM_006004
UQCRH
ubiquinol-cytochrome c reductase hinge protein
chr1_+_159986217 1.322 DUSP12
dual specificity phosphatase 12
chr6_+_143423656 1.321 NM_016108
AIG1
androgen-induced 1
chr2_+_170298487 1.317


chr19_+_39355280 1.304 LSM14A
LSM14A, SCD6 homolog A (S. cerevisiae)
chr5_-_180603476 1.302 NM_006098
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr11_+_5367182 1.299 NM_001004756
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr4_-_186970366 1.294 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr18_+_53253775 1.292 NM_004852
ONECUT2
one cut homeobox 2
chr2_-_174537021 1.292 NM_001017371
SP3
Sp3 transcription factor
chr19_+_54160369 1.292 NM_000146
FTL
ferritin, light polypeptide
chr16_+_69115227 1.286 SF3B3
splicing factor 3b, subunit 3, 130kDa
chr17_-_70901303 1.285 GRB2
growth factor receptor-bound protein 2
chr2_+_170298700 1.282 KLHL23
kelch-like 23 (Drosophila)
chrX_+_70360184 1.280 GJB1
gap junction protein, beta 1, 32kDa
chr2_-_166638376 1.279 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr21_+_33844793 1.279 SON
SON DNA binding protein
chr6_+_41128917 1.273 NM_006789
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr1_-_75854281 1.273 SLC44A5
solute carrier family 44, member 5
chr18_+_9904249 1.269 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr6_+_105511615 1.265 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr2_-_128000315 1.265 NM_017969
IWS1
IWS1 homolog (S. cerevisiae)
chr6_-_47362102 1.264 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr11_+_75203884 1.261 UVRAG
UV radiation resistance associated gene
chr6_+_43373972 1.258 NM_006672
NM_153320
SLC22A7

solute carrier family 22 (organic anion transporter), member 7

chr1_-_198643885 1.258 ZNF281
zinc finger protein 281
chr17_-_70690625 1.255 SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr20_-_33793286 1.241 RBM39
RNA binding motif protein 39
chr19_-_12858956 1.241 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr2_-_70329067 1.235 NM_022037
NM_022173
TIA1

TIA1 cytotoxic granule-associated RNA binding protein

chr3_-_12680612 1.234 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chrX_-_24600661 1.227 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr9_-_122382079 1.227 NM_001011649
NM_018249
CDK5RAP2

CDK5 regulatory subunit associated protein 2

chr17_+_43082557 1.219 KPNB1
karyopherin (importin) beta 1
chr9_+_130124873 1.218 COQ4
coenzyme Q4 homolog (S. cerevisiae)
chr3_+_180805266 1.213 NM_002492
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr17_-_77093468 1.212 ACTG1
actin, gamma 1
chr1_+_178190493 1.210 NM_014810
CEP350
centrosomal protein 350kDa
chr1_-_78217278 1.210 FUBP1
far upstream element (FUSE) binding protein 1
chr2_-_21081694 1.207 APOB
apolipoprotein B (including Ag(x) antigen)
chr6_-_44388964 1.206 NM_020745
AARS2
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr1_+_229181462 1.200 ARV1
ARV1 homolog (S. cerevisiae)
chr6_+_36670113 1.198 SRSF3
serine/arginine-rich splicing factor 3
chr2_+_74610751 1.195 HTRA2
HtrA serine peptidase 2
chr6_-_47361921 1.194 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr3_-_14964620 1.193


chr7_-_23537968 1.192 NM_013293
TRA2A
transformer 2 alpha homolog (Drosophila)
chr1_+_78217510 1.189 DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr4_-_174774368 1.186 NM_006792
MORF4
mortality factor 4
chr17_+_68700781 1.186 COG1
component of oligomeric golgi complex 1
chr2_-_43919392 1.185 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr17_+_55052065 1.181 CLTC
clathrin, heavy chain (Hc)
chr17_-_71285992 1.181 H3F3B
H3 histone, family 3B (H3.3B)
chr7_+_155129904 1.172 RBM33
RNA binding motif protein 33
chr16_-_21439195 1.168 SLC7A5P2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 pseudogene 2
chr2_+_96355661 1.168 NM_178495
NM_001163524
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr2_+_48521411 1.164 NM_001135629
NM_001193475
NM_152994
KLRAQ1


KLRAQ motif containing 1


chrX_+_70359780 1.156 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chr14_-_54438913 1.154 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr6_+_36670117 1.153 SRSF3
serine/arginine-rich splicing factor 3
chr1_-_246789396 1.151 NM_001004694
OR2T29
OR2T5
olfactory receptor, family 2, subfamily T, member 29
olfactory receptor, family 2, subfamily T, member 5
chr8_-_107023 1.149 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr16_-_45212804 1.148 NM_024745
SHCBP1
SHC SH2-domain binding protein 1
chr4_+_84175262 1.145 NM_016129
COPS4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr19_-_14062230 1.136 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr11_-_118167073 1.131 DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr9_-_67945114 1.130 LOC283788
LOC642236
FSHD region gene 1 pseudogene
FSHD region gene 1 pseudogene
chr1_-_226661089 1.118 NM_145214
TRIM11
tripartite motif containing 11
chr1_+_87569959 1.118 LMO4
LIM domain only 4
chr10_+_28862514 1.117 WAC
WW domain containing adaptor with coiled-coil
chr20_+_36988469 1.115 FAM83D
family with sequence similarity 83, member D
chr3_-_33675484 1.113 CLASP2
cytoplasmic linker associated protein 2
chrX_-_73751135 1.111 RLIM
ring finger protein, LIM domain interacting
chr8_+_125556130 1.108 NM_007218
RNF139
ring finger protein 139
chr19_+_39355151 1.102 NM_001114093
NM_015578
LSM14A

LSM14A, SCD6 homolog A (S. cerevisiae)

chr14_-_34943574 1.095 NM_020529
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr17_-_45901173 1.093 NM_001267
CHAD
chondroadherin
chr10_+_28862429 1.090 NM_016628
NM_100486
WAC

WW domain containing adaptor with coiled-coil

chr17_-_71861292 1.089 PRPSAP1
phosphoribosyl pyrophosphate synthetase-associated protein 1
chr3_+_129682434 1.088


chr11_-_118166797 1.087 DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr6_+_149929175 1.086 NM_138785
C6orf72
chromosome 6 open reading frame 72
chr2_+_182464910 1.086 SSFA2
sperm specific antigen 2
chr17_+_68700739 1.084 NM_018714
COG1
component of oligomeric golgi complex 1
chr12_-_107479082 1.082 SART3
squamous cell carcinoma antigen recognized by T cells 3
chr22_-_40941254 1.078 NM_005650
NM_181492
TCF20

transcription factor 20 (AR1)

chr3_+_142939725 1.071 NM_014245
NM_183237
RNF7

ring finger protein 7

chrX_-_129347101 1.071 NM_178471
GPR119
G protein-coupled receptor 119
chr12_-_85756766 1.070 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr7_-_72574528 1.068 NM_032408
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr12_+_56230110 1.065 NM_004984
KIF5A
kinesin family member 5A
chr3_-_12680329 1.063 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr5_+_10303410 1.060 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr5_+_126140949 1.058 LMNB1
lamin B1
chr8_-_145019421 1.057 NM_031308
EPPK1
epiplakin 1
chr8_+_97343282 1.055 PTDSS1
phosphatidylserine synthase 1
chr9_-_14769530 1.052 NM_001177704
FREM1
FRAS1 related extracellular matrix 1
chr11_+_67871999 1.050 LRP5
low density lipoprotein receptor-related protein 5
chr8_-_55097533 1.050 NM_006756
NM_201437
TCEA1

transcription elongation factor A (SII), 1

chrX_+_78313124 1.043 NM_032553
GPR174
G protein-coupled receptor 174
chr2_+_170074457 1.041 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr14_-_34661156 1.040 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.25 5.22e-54 GO:0044237 cellular metabolic process
1.31 3.56e-50 GO:0044260 cellular macromolecule metabolic process
1.19 2.59e-40 GO:0008152 metabolic process
1.21 3.96e-39 GO:0044238 primary metabolic process
1.25 8.02e-38 GO:0043170 macromolecule metabolic process
1.45 8.09e-37 GO:0010467 gene expression
1.45 1.15e-33 GO:0016070 RNA metabolic process
1.38 4.32e-32 GO:0090304 nucleic acid metabolic process
1.33 1.08e-30 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.68 1.48e-26 GO:0006396 RNA processing
1.28 2.04e-26 GO:0034641 cellular nitrogen compound metabolic process
1.32 3.08e-26 GO:0044267 cellular protein metabolic process
1.74 4.07e-26 GO:0016071 mRNA metabolic process
1.27 2.97e-25 GO:0006807 nitrogen compound metabolic process
1.80 1.35e-21 GO:0006397 mRNA processing
1.83 1.14e-18 GO:0006412 translation
1.83 4.56e-18 GO:0008380 RNA splicing
1.28 5.62e-18 GO:0044249 cellular biosynthetic process
1.26 2.99e-16 GO:0009058 biosynthetic process
1.32 3.35e-16 GO:0034645 cellular macromolecule biosynthetic process
1.32 5.22e-16 GO:0009059 macromolecule biosynthetic process
1.23 8.90e-16 GO:0019538 protein metabolic process
1.08 1.46e-15 GO:0009987 cellular process
1.92 1.69e-14 GO:0000375 RNA splicing, via transesterification reactions
1.92 3.56e-14 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.92 3.56e-14 GO:0000398 nuclear mRNA splicing, via spliceosome
1.57 3.45e-11 GO:0016032 viral reproduction
1.46 7.52e-11 GO:0051276 chromosome organization
1.49 1.98e-10 GO:0044265 cellular macromolecule catabolic process
1.40 2.12e-10 GO:0046907 intracellular transport
1.27 4.10e-10 GO:0006996 organelle organization
2.05 4.86e-10 GO:0051028 mRNA transport
1.99 5.00e-10 GO:0006403 RNA localization
2.00 5.07e-10 GO:0050657 nucleic acid transport
2.00 5.07e-10 GO:0050658 RNA transport
2.00 5.07e-10 GO:0051236 establishment of RNA localization
2.16 2.61e-09 GO:0019080 viral genome expression
2.16 2.61e-09 GO:0019083 viral transcription
2.05 4.04e-09 GO:0006414 translational elongation
2.12 6.60e-09 GO:0006415 translational termination
1.88 9.91e-09 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.48 1.59e-08 GO:0006325 chromatin organization
1.47 1.80e-08 GO:0034621 cellular macromolecular complex subunit organization
1.42 2.34e-08 GO:0009057 macromolecule catabolic process
1.81 3.23e-08 GO:0022415 viral reproductive process
1.18 3.82e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.53 4.52e-08 GO:0016568 chromatin modification
1.86 7.10e-08 GO:0019058 viral infectious cycle
1.32 8.13e-08 GO:0032774 RNA biosynthetic process
1.29 8.26e-08 GO:0044248 cellular catabolic process
1.55 1.54e-07 GO:0043632 modification-dependent macromolecule catabolic process
1.26 2.14e-07 GO:0033036 macromolecule localization
1.41 2.33e-07 GO:0000278 mitotic cell cycle
1.21 2.84e-07 GO:0043412 macromolecule modification
1.54 3.79e-07 GO:0019941 modification-dependent protein catabolic process
1.88 3.85e-07 GO:0031018 endocrine pancreas development
1.33 5.07e-07 GO:0043933 macromolecular complex subunit organization
1.54 5.47e-07 GO:0006511 ubiquitin-dependent protein catabolic process
1.32 8.29e-07 GO:0015031 protein transport
1.90 9.05e-07 GO:0032984 macromolecular complex disassembly
1.90 9.05e-07 GO:0034623 cellular macromolecular complex disassembly
1.21 9.35e-07 GO:0006464 protein modification process
1.29 1.19e-06 GO:0007049 cell cycle
1.31 1.60e-06 GO:0045184 establishment of protein localization
1.51 2.21e-06 GO:0051603 proteolysis involved in cellular protein catabolic process
1.27 2.49e-06 GO:0051649 establishment of localization in cell
1.55 2.76e-06 GO:0010608 posttranscriptional regulation of gene expression
1.67 3.50e-06 GO:0016569 covalent chromatin modification
1.25 3.98e-06 GO:0051641 cellular localization
1.92 4.23e-06 GO:0043241 protein complex disassembly
1.92 4.23e-06 GO:0043624 cellular protein complex disassembly
1.76 5.10e-06 GO:0031016 pancreas development
1.14 5.52e-06 GO:0071840 cellular component organization or biogenesis
1.17 5.68e-06 GO:0071842 cellular component organization at cellular level
1.49 6.42e-06 GO:0044257 cellular protein catabolic process
1.67 6.62e-06 GO:0051169 nuclear transport
1.47 6.65e-06 GO:0044419 interspecies interaction between organisms
1.67 7.38e-06 GO:0006913 nucleocytoplasmic transport
1.51 1.02e-05 GO:0051325 interphase
1.79 1.04e-05 GO:0045333 cellular respiration
1.64 1.07e-05 GO:0022411 cellular component disassembly
1.64 1.07e-05 GO:0071845 cellular component disassembly at cellular level
1.27 1.22e-05 GO:0008104 protein localization
1.65 1.68e-05 GO:0016570 histone modification
1.56 1.91e-05 GO:0032269 negative regulation of cellular protein metabolic process
1.50 1.99e-05 GO:0051329 interphase of mitotic cell cycle
1.46 2.13e-05 GO:0018193 peptidyl-amino acid modification
1.30 2.39e-05 GO:0033554 cellular response to stress
1.46 2.54e-05 GO:0030163 protein catabolic process
1.38 2.64e-05 GO:0006974 response to DNA damage stimulus
1.30 3.59e-05 GO:0022402 cell cycle process
1.60 6.45e-05 GO:0022613 ribonucleoprotein complex biogenesis
1.58 8.21e-05 GO:0071843 cellular component biogenesis at cellular level
1.32 8.69e-05 GO:0022403 cell cycle phase
2.04 8.72e-05 GO:0031124 mRNA 3'-end processing
1.85 1.02e-04 GO:0022904 respiratory electron transport chain
1.21 1.03e-04 GO:0009056 catabolic process
1.52 1.05e-04 GO:0051248 negative regulation of protein metabolic process
1.13 2.01e-04 GO:0016043 cellular component organization
1.63 2.26e-04 GO:0006417 regulation of translation
1.72 2.46e-04 GO:0042254 ribosome biogenesis
1.59 3.86e-04 GO:0035270 endocrine system development
2.24 4.58e-04 GO:0006413 translational initiation
1.68 4.80e-04 GO:0022900 electron transport chain
1.25 1.04e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.64 1.05e-03 GO:0000082 G1/S transition of mitotic cell cycle
1.87 1.07e-03 GO:0031123 RNA 3'-end processing
1.31 1.29e-03 GO:0071822 protein complex subunit organization
1.38 1.42e-03 GO:0006886 intracellular protein transport
1.82 1.52e-03 GO:0051168 nuclear export
1.58 2.30e-03 GO:0031400 negative regulation of protein modification process
1.40 2.47e-03 GO:0070647 protein modification by small protein conjugation or removal
1.24 2.47e-03 GO:0031324 negative regulation of cellular metabolic process
1.80 2.58e-03 GO:0006402 mRNA catabolic process
1.32 4.47e-03 GO:0070727 cellular macromolecule localization
1.50 5.94e-03 GO:0006605 protein targeting
1.68 6.30e-03 GO:0006401 RNA catabolic process
1.31 6.65e-03 GO:0034613 cellular protein localization
1.51 6.81e-03 GO:0034470 ncRNA processing
1.66 8.55e-03 GO:0051320 S phase
1.22 8.82e-03 GO:0009892 negative regulation of metabolic process
1.23 9.20e-03 GO:0006351 transcription, DNA-dependent
1.20 9.22e-03 GO:0044085 cellular component biogenesis
1.79 1.01e-02 GO:0000956 nuclear-transcribed mRNA catabolic process
2.09 1.26e-02 GO:0017148 negative regulation of translation
1.41 1.49e-02 GO:0032446 protein modification by small protein conjugation
1.83 1.52e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.41 1.68e-02 GO:0034660 ncRNA metabolic process
1.53 1.80e-02 GO:0010498 proteasomal protein catabolic process
1.53 1.80e-02 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.72 1.82e-02 GO:0031397 negative regulation of protein ubiquitination
1.78 2.01e-02 GO:0006353 transcription termination, DNA-dependent
1.39 2.09e-02 GO:0006366 transcription from RNA polymerase II promoter
1.79 2.19e-02 GO:0006473 protein acetylation
1.73 2.22e-02 GO:0043543 protein acylation
1.79 2.39e-02 GO:0051352 negative regulation of ligase activity
1.79 2.39e-02 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.63 2.39e-02 GO:0000084 S phase of mitotic cell cycle
1.45 2.83e-02 GO:0000075 cell cycle checkpoint
1.26 2.98e-02 GO:0051726 regulation of cell cycle
1.82 3.06e-02 GO:0018394 peptidyl-lysine acetylation
1.20 3.07e-02 GO:0032268 regulation of cellular protein metabolic process
1.83 3.30e-02 GO:0016573 histone acetylation
1.50 3.77e-02 GO:0043687 post-translational protein modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 7.84e-65 GO:0044424 intracellular part
1.13 9.71e-61 GO:0005622 intracellular
1.16 6.62e-54 GO:0043229 intracellular organelle
1.16 7.53e-54 GO:0043226 organelle
1.17 2.31e-52 GO:0043227 membrane-bounded organelle
1.17 6.39e-52 GO:0043231 intracellular membrane-bounded organelle
1.24 1.01e-45 GO:0044446 intracellular organelle part
1.24 6.52e-45 GO:0044422 organelle part
1.41 2.55e-40 GO:0070013 intracellular organelle lumen
1.40 3.37e-40 GO:0043233 organelle lumen
1.16 4.00e-40 GO:0005737 cytoplasm
1.40 9.84e-40 GO:0031974 membrane-enclosed lumen
1.41 2.93e-38 GO:0044428 nuclear part
1.30 5.98e-37 GO:0032991 macromolecular complex
1.43 9.74e-35 GO:0031981 nuclear lumen
1.20 4.73e-34 GO:0044444 cytoplasmic part
1.21 7.19e-33 GO:0005634 nucleus
1.81 1.01e-32 GO:0030529 ribonucleoprotein complex
1.44 5.36e-26 GO:0005654 nucleoplasm
1.31 1.97e-20 GO:0005829 cytosol
1.04 1.40e-18 GO:0044464 cell part
1.04 1.62e-18 GO:0005623 cell
1.96 4.20e-16 GO:0005840 ribosome
1.23 7.56e-16 GO:0043228 non-membrane-bounded organelle
1.23 7.56e-16 GO:0043232 intracellular non-membrane-bounded organelle
1.21 1.03e-14 GO:0043234 protein complex
1.32 1.36e-13 GO:0005739 mitochondrion
2.00 2.28e-12 GO:0005681 spliceosomal complex
1.41 1.47e-11 GO:0044451 nucleoplasm part
2.20 3.29e-10 GO:0071013 catalytic step 2 spliceosome
1.44 5.30e-10 GO:0005694 chromosome
1.44 7.83e-09 GO:0005730 nucleolus
2.14 1.66e-08 GO:0022626 cytosolic ribosome
1.79 1.66e-08 GO:0044445 cytosolic part
1.42 4.60e-07 GO:0044427 chromosomal part
1.32 3.32e-06 GO:0044429 mitochondrial part
2.06 6.51e-06 GO:0000123 histone acetyltransferase complex
1.54 7.09e-06 GO:0000785 chromatin
1.29 2.75e-05 GO:0031967 organelle envelope
1.52 4.90e-05 GO:0016604 nuclear body
2.01 5.68e-05 GO:0015934 large ribosomal subunit
1.28 8.36e-05 GO:0031975 envelope
1.43 8.83e-05 GO:0005743 mitochondrial inner membrane
1.41 1.47e-04 GO:0019866 organelle inner membrane
1.15 1.76e-04 GO:0031090 organelle membrane
1.96 2.26e-04 GO:0005746 mitochondrial respiratory chain
2.18 7.96e-04 GO:0022625 cytosolic large ribosomal subunit
1.98 9.69e-04 GO:0015935 small ribosomal subunit
1.86 1.35e-03 GO:0070469 respiratory chain
2.66 1.36e-03 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.62 1.64e-03 GO:0044455 mitochondrial membrane part
1.32 1.84e-03 GO:0031966 mitochondrial membrane
1.45 2.15e-03 GO:0005813 centrosome
1.82 2.19e-03 GO:0005643 nuclear pore
1.42 2.30e-03 GO:0005759 mitochondrial matrix
2.07 4.13e-03 GO:0005747 mitochondrial respiratory chain complex I
2.07 4.13e-03 GO:0030964 NADH dehydrogenase complex
2.07 4.13e-03 GO:0045271 respiratory chain complex I
1.44 5.80e-03 GO:0000228 nuclear chromosome
1.88 6.70e-03 GO:0034708 methyltransferase complex
1.88 6.70e-03 GO:0035097 histone methyltransferase complex
1.29 8.19e-03 GO:0005740 mitochondrial envelope
1.69 9.40e-03 GO:0046930 pore complex
1.51 2.15e-02 GO:0000151 ubiquitin ligase complex
1.76 2.62e-02 GO:0000502 proteasome complex
2.02 3.70e-02 GO:0022627 cytosolic small ribosomal subunit

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.70 2.18e-39 GO:0003723 RNA binding
1.16 6.74e-32 GO:0005515 protein binding
1.24 7.55e-14 GO:0000166 nucleotide binding
1.98 4.93e-13 GO:0003735 structural constituent of ribosome
1.18 8.86e-12 GO:0003676 nucleic acid binding
1.06 4.97e-11 GO:0005488 binding
1.10 6.11e-06 GO:0003824 catalytic activity
1.20 1.35e-05 GO:0030554 adenyl nucleotide binding
1.21 1.38e-05 GO:0032559 adenyl ribonucleotide binding
1.18 4.22e-05 GO:0017076 purine nucleotide binding
1.18 4.74e-05 GO:0032553 ribonucleotide binding
1.18 4.74e-05 GO:0032555 purine ribonucleotide binding
1.20 6.87e-05 GO:0005524 ATP binding
1.39 2.07e-04 GO:0003712 transcription cofactor activity
1.17 2.30e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.39 2.59e-04 GO:0000988 protein binding transcription factor activity
1.39 2.59e-04 GO:0000989 transcription factor binding transcription factor activity
1.35 2.69e-04 GO:0016874 ligase activity
1.86 2.88e-04 GO:0003729 mRNA binding
1.81 8.06e-04 GO:0008135 translation factor activity, nucleic acid binding
2.06 8.90e-04 GO:0003743 translation initiation factor activity
1.43 1.24e-02 GO:0003713 transcription coactivator activity
1.95 3.10e-02 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
2.02 3.32e-02 GO:0003954 NADH dehydrogenase activity
2.02 3.32e-02 GO:0008137 NADH dehydrogenase (ubiquinone) activity
2.02 3.32e-02 GO:0050136 NADH dehydrogenase (quinone) activity
1.47 4.75e-02 GO:0004721 phosphoprotein phosphatase activity