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Motif ID: RREB1.p2

Z-value: 0.683

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_+_187917791	4.472	NM_000893 NM_001102416 NM_001166451	KNG1	kininogen 1
chr11_-_133786935	4.109	NM_018644 NM_054025	B3GAT1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr4_+_191245840	4.106	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr4_-_809879	3.687	NM_006651	CPLX1	complexin 1
chr4_+_191232653	3.681	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr4_+_191239247	2.710	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr10_+_135343649	2.695	NM_012147	DUX2	double homeobox 2
chr4_+_191226073	2.644	NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467	DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3	double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3
chr10_+_135330357	2.245	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr10_+_135333667	2.166	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr22_+_49459935	2.157	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr7_+_100792841	2.155	NM_133457	EMID2	EMI domain containing 2
chr4_+_191242540	2.120	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr19_+_3317575	2.059		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr2_+_174907914	2.054	NM_001145250	SP9	Sp9 transcription factor homolog (mouse)
chr21_+_42946719	1.962	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr20_-_22512893	1.953		FOXA2	forkhead box A2
chr7_+_100111689	1.949		GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr17_-_44047299	1.934	NM_024016	HOXB8	homeobox B8
chr4_+_191229360	1.917	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chrX_-_119133802	1.883	NM_139282	RHOXF1	Rhox homeobox family, member 1
chr20_+_48032918	1.866	NM_005985	SNAI1	snail homolog 1 (Drosophila)
chr2_+_26768894	1.861	NM_002246	KCNK3	potassium channel, subfamily K, member 3
chr14_+_104244998	1.848		INF2	inverted formin, FH2 and WH2 domain containing
chr22_+_49333327	1.841	NM_138433	KLHDC7B	kelch domain containing 7B
chr7_-_100331417	1.832	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr20_-_61574259	1.805	NM_004518 NM_172106 NM_172107 NM_172108 NM_172109	KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2
chr19_+_40213431	1.790	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chr19_+_3317589	1.762		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr14_+_28305922	1.730	NM_005249	FOXG1	forkhead box G1
chr8_-_145725289	1.706		C8orf82	chromosome 8 open reading frame 82
chr21_-_46428788	1.692	NM_001142854 NM_032261	C21orf56	chromosome 21 open reading frame 56
chrX_+_151975421	1.681	NM_013364	PNMA3	paraneoplastic antigen MA3
chr11_-_76058542	1.677	NM_005512	LRRC32	leucine rich repeat containing 32
chr4_+_191235959	1.650	NM_001177376	DUX4L4	double homeobox 4 like 4
chr14_-_36121536	1.649	NM_014360	NKX2-8	NK2 homeobox 8
chr19_-_51168396	1.643	NM_002516	NOVA2	neuro-oncological ventral antigen 2
chr10_-_133995323	1.623		STK32C	serine/threonine kinase 32C
chr8_+_37672427	1.610	NM_025069	ZNF703	zinc finger protein 703
chr9_-_43570725	1.591	NM_001145196	FAM75A6	family with sequence similarity 75, member A6
chrX_+_151975518	1.590		PNMA3	paraneoplastic antigen MA3
chr1_-_40903897	1.590	NM_014747	RIMS3	regulating synaptic membrane exocytosis 3
chr2_+_219453487	1.588	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr1_-_34404029	1.575	NM_052896	CSMD2	CUB and Sushi multiple domains 2
chr20_-_26137755	1.558		LOC284801	hypothetical protein LOC284801
chr8_-_145136125	1.533		PARP10	poly (ADP-ribose) polymerase family, member 10
chr7_-_150411345	1.531	NM_031434	TMUB1	transmembrane and ubiquitin-like domain containing 1
chr2_+_72998111	1.529	NM_004097	EMX1	empty spiracles homeobox 1
chr1_+_1940605	1.515	NM_000815	GABRD	gamma-aminobutyric acid (GABA) A receptor, delta
chr17_+_62391216	1.501	NM_014405	CACNG4	calcium channel, voltage-dependent, gamma subunit 4
chr16_+_1143738	1.491		CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr21_-_44506526	1.466	NM_013369 NM_175867	DNMT3L	DNA (cytosine-5-)-methyltransferase 3-like
chr1_+_945331	1.453	NM_198576	AGRN	agrin
chr8_-_41624030	1.447	NM_152568	NKX6-3	NK6 homeobox 3
chr19_+_13924318	1.433	NM_138353	DCAF15	DDB1 and CUL4 associated factor 15
chr19_-_52667056	1.418	NM_015063	SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chrX_-_151057615	1.414	NM_001011543 NM_021048	MAGEA10	melanoma antigen family A, 10
chr19_+_60691671	1.411	NM_001144950 NM_001195267	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr8_-_111056099	1.411	NM_014379	KCNV1	potassium channel, subfamily V, member 1
chr19_-_360138	1.394	NM_001136263	C2CD4C	C2 calcium-dependent domain containing 4C
chr1_+_144183811	1.388		ANKRD34A	ankyrin repeat domain 34A
chr17_+_39741306	1.364	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chr20_+_13924014	1.357	NM_080676	MACROD2	MACRO domain containing 2
chr7_+_44110470	1.344	NM_001129	AEBP1	AE binding protein 1
chr7_+_44110527	1.320		AEBP1	AE binding protein 1
chr8_-_145725197	1.318	NM_001001795	C8orf82	chromosome 8 open reading frame 82
chrX_-_151653756	1.316	NM_001166386 NM_001166387 NM_005367	MAGEA12	melanoma antigen family A, 12
chr19_+_13924287	1.315		DCAF15	DDB1 and CUL4 associated factor 15
chr1_-_226670928	1.312		TRIM17	tripartite motif containing 17
chr4_+_54660954	1.309	NM_133267	GSX2	GS homeobox 2
chr11_-_6633427	1.306	NM_003737	DCHS1	dachsous 1 (Drosophila)
chr18_+_42168180	1.303	NM_152470	C18orf23 RNF165	chromosome 18 open reading frame 23 ring finger protein 165
chr20_-_62151216	1.291	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr7_-_143731718	1.287	NM_001080413	NOBOX	NOBOX oogenesis homeobox
chr8_+_144706699	1.282	NM_001166237	GSDMD	gasdermin D
chr7_-_150411504	1.277	NM_001136044	TMUB1	transmembrane and ubiquitin-like domain containing 1
chr21_-_46473143	1.267	NM_001001438 NM_001145436 NM_001145437 NM_002340	LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr2_+_200031333	1.266
chrX_+_152643516	1.264	NM_000033	ABCD1	ATP-binding cassette, sub-family D (ALD), member 1
chr19_+_540849	1.261	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr19_-_13977875	1.258		RFX1	regulatory factor X, 1 (influences HLA class II expression)
chr7_-_75876830	1.252	NM_080744	SRCRB4D	scavenger receptor cysteine rich domain containing, group B (4 domains)
chr6_-_32184975	1.247	NM_019105	TNXB	tenascin XB
chr14_+_23907065	1.246	NM_001198965 NM_004554	NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr11_-_76059435	1.240	NM_001128922	LRRC32	leucine rich repeat containing 32
chr1_-_226671205	1.238	NM_001024940 NM_001134855 NM_016102	TRIM17	tripartite motif containing 17
chr19_+_61344341	1.229	NM_018337	ZNF444	zinc finger protein 444
chr17_+_76988134	1.228	NM_001080519	BAHCC1	BAH domain and coiled-coil containing 1
chr13_+_44813479	1.223		LOC100190939	hypothetical LOC100190939
chr19_-_55763091	1.222	NM_001080457	LRRC4B	leucine rich repeat containing 4B
chr17_-_73636362	1.218		TMC6	transmembrane channel-like 6
chr12_-_46439127	1.218	NM_001098531	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr14_+_23937766	1.209	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr1_-_154484341	1.202	NM_198406 NM_024897	PAQR6	progestin and adipoQ receptor family member VI
chr19_-_295778	1.202	NM_017550	MIER2	mesoderm induction early response 1, family member 2
chr21_-_46473100	1.176		LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr15_+_72209973	1.173		ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr10_-_98935652	1.170	NM_003061	SLIT1	slit homolog 1 (Drosophila)
chr7_+_100111712	1.167		GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr16_+_1143241	1.163	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr12_+_6800950	1.162	NM_014449 NM_019858	GPR162	G protein-coupled receptor 162
chr11_-_74740298	1.156	NM_004041 NM_020251	ARRB1	arrestin, beta 1
chr19_+_61344501	1.155		ZNF444	zinc finger protein 444
chr1_+_199259664	1.153
chr21_-_46473046	1.145		LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr17_-_30724732	1.133	NM_001104587 NM_001104588 NM_001104589 NM_001104590 NM_152270	SLFN11	schlafen family member 11
chr19_-_34897802	1.127	NM_001031726	C19orf12	chromosome 19 open reading frame 12
chr19_+_14405100	1.122	NM_002741	PKN1	protein kinase N1
chr11_-_69228286	1.118	NM_005117	FGF19	fibroblast growth factor 19
chr1_+_945399	1.112
chr16_-_65516919	1.111	NM_001128850 NM_004165	RRAD	Ras-related associated with diabetes
chr5_+_2805261	1.102	NM_178569	C5orf38	chromosome 5 open reading frame 38
chr22_+_36286350	1.097	NM_152243	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1
chr3_-_10522267	1.096	NM_001001331 NM_001683	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr19_-_8581559	1.094	NM_030957	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr5_+_146594718	1.087	NM_001112724 NM_145001	STK32A	serine/threonine kinase 32A
chr22_-_29052863	1.072	NM_031937	TBC1D10A	TBC1 domain family, member 10A
chr11_-_17454995	1.071	NM_000352	ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr10_+_120957084	1.070	NM_005308	GRK5	G protein-coupled receptor kinase 5
chr17_+_5914364	1.069	NM_015253	WSCD1	WSC domain containing 1
chr14_-_20636568	1.065	NM_016423	ZNF219	zinc finger protein 219
chr1_+_154318954	1.064		LMNA	lamin A/C
chr1_-_1525309	1.060		LOC643988	hypothetical LOC643988
chr7_+_75770801	1.057		HSPB1	heat shock 27kDa protein 1
chr15_+_72209795	1.055	NM_020851	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr9_+_136358145	1.051		RXRA	retinoid X receptor, alpha
chr11_-_124137260	1.048	NM_138961	ESAM	endothelial cell adhesion molecule
chrX_-_48976714	1.043	NM_005183	CACNA1F	calcium channel, voltage-dependent, L type, alpha 1F subunit
chr12_+_6807831	1.041	NM_014262	LEPREL2	leprecan-like 2
chr9_+_35896188	1.041	NM_001039792	HRCT1	histidine rich carboxyl terminus 1
chr3_+_12304332	1.036	NM_005037 NM_138712	PPARG	peroxisome proliferator-activated receptor gamma
chr11_+_128266460	1.026	NM_000890	KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5
chr12_-_53268538	1.023	NM_006741	PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr20_-_3610635	1.020	NM_025220 NM_153202	ADAM33	ADAM metallopeptidase domain 33
chr7_-_74705276	1.018	NM_001145064	GATSL2	GATS protein-like 2
chr17_+_7846636	1.017	NM_000180	GUCY2D	guanylate cyclase 2D, membrane (retina-specific)
chr17_-_36981830	1.012	NM_000226	KRT9	keratin 9
chr14_-_20636337	1.010		ZNF219	zinc finger protein 219
chr19_-_53706644	1.010
chr12_+_56435042	1.006	NM_138396	MARCH9	membrane-associated ring finger (C3HC4) 9
chr6_-_36915712	1.005		CPNE5	copine V
chr8_-_145530639	1.004	NM_031309	SCRT1	scratch homolog 1, zinc finger protein (Drosophila)
chr22_-_42589543	0.996	NM_014351	SULT4A1	sulfotransferase family 4A, member 1
chr5_+_128823904	0.995	NM_133638	ADAMTS19	ADAM metallopeptidase with thrombospondin type 1 motif, 19
chr5_-_2804768	0.993	NM_001134222 NM_033267	IRX2	iroquois homeobox 2
chr19_-_242335	0.990	NM_003712 NM_177526	PPAP2C	phosphatidic acid phosphatase type 2C
chr2_+_219532590	0.987	NM_003936	CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr20_-_33489383	0.986	NM_000557	GDF5	growth differentiation factor 5
chr17_-_40866062	0.985	NM_174919	SH3D20	SH3 domain containing 20
chr8_-_145119627	0.984	NM_201378	PLEC	plectin
chr19_-_242168	0.982	NM_177543	PPAP2C	phosphatidic acid phosphatase type 2C
chr2_+_20729904	0.974	NM_182828	GDF7	growth differentiation factor 7
chr1_+_47654330	0.974	NM_012186	FOXE3	forkhead box E3
chr5_-_176833197	0.972		DBN1	drebrin 1
chr10_-_95350949	0.970	NM_006744	RBP4	retinol binding protein 4, plasma
chrX_+_51944658	0.964	NM_001098800 NM_030801 NM_177535 NM_177537	MAGED4 MAGED4B	melanoma antigen family D, 4 melanoma antigen family D, 4B
chr15_-_86600658	0.961	NM_001007156 NM_001012338 NM_002530	NTRK3	neurotrophic tyrosine kinase, receptor, type 3
chr19_+_3317536	0.959	NM_005597	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr1_+_945472	0.952		AGRN	agrin
chr22_-_28992787	0.952	NM_020530	OSM	oncostatin M
chr19_+_45996881	0.950	NM_080732	EGLN2	egl nine homolog 2 (C. elegans)
chrX_+_66680593	0.947	NM_000044	AR	androgen receptor
chrX_-_151672985	0.942	NM_005361 NM_175742 NM_175743	MAGEA2	melanoma antigen family A, 2
chr7_-_150129295	0.937	NM_014020	TMEM176B	transmembrane protein 176B
chr10_-_133995315	0.937		STK32C	serine/threonine kinase 32C
chr19_+_12995782	0.935		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr5_+_145698779	0.932	NM_002700	POU4F3	POU class 4 homeobox 3
chr17_-_28644118	0.931	NM_183377	ACCN1	amiloride-sensitive cation channel 1, neuronal
chr19_+_60691733	0.928		SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr6_-_163754903	0.928		LOC100526820	hypothetical LOC100526820
chr9_+_136358134	0.926	NM_002957	RXRA	retinoid X receptor, alpha
chr8_+_120497732	0.925	NM_002514	NOV	nephroblastoma overexpressed gene
chr11_+_279113	0.921	NM_025092	ATHL1	ATH1, acid trehalase-like 1 (yeast)
chr2_+_176695658	0.920	NM_014213	HOXD9	homeobox D9
chr19_+_54786723	0.918	NM_020719	PRR12	proline rich 12
chr8_-_28299508	0.917		ZNF395	zinc finger protein 395
chr7_+_74017015	0.916	NM_001145063	GATSL1 GATSL2	GATS protein-like 1 GATS protein-like 2
chrX_-_70067650	0.912	NM_001048164 NM_032803	SLC7A3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr16_-_69030421	0.911	NM_006927	ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr22_-_41913076	0.902	NM_015140	TTLL12	tubulin tyrosine ligase-like family, member 12
chr1_+_1066138	0.901
chr11_+_10283171	0.888	NM_001124	ADM	adrenomedullin
chrX_-_48578878	0.887	NM_013271	PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor
chr16_-_1215254	0.883	NM_012467	TPSG1	tryptase gamma 1
chr1_-_16272523	0.881	NM_182623	FAM131C	family with sequence similarity 131, member C
chr14_-_62581656	0.881	NM_139318 NM_172375	KCNH5	potassium voltage-gated channel, subfamily H (eag-related), member 5
chr18_+_75261231	0.876	NM_172387 NM_172389	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr19_-_7845325	0.869	NM_001190467	FLJ22184	hypothetical protein FLJ22184
chr9_+_115958051	0.858	NM_032888	COL27A1	collagen, type XXVII, alpha 1
chr21_-_43368963	0.857	NM_000071	CBS	cystathionine-beta-synthase
chr16_+_28741873	0.855		ATXN2L	ataxin 2-like
chr19_-_52666886	0.854		SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chr3_+_194441586	0.852	NM_020386	HRASLS	HRAS-like suppressor
chr12_+_56135353	0.851	NM_031479	INHBE	inhibin, beta E
chr2_-_128149112	0.848	NM_001136037 NM_001161403	LIMS2	LIM and senescent cell antigen-like domains 2
chr8_-_144694754	0.848	NM_015117	ZC3H3	zinc finger CCCH-type containing 3
chr15_+_72208751	0.847	NM_001130136	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr21_-_46472835	0.845		LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr9_-_116307531	0.842	NM_001173425 NM_015404	DFNB31	deafness, autosomal recessive 31
chr9_-_139235595	0.838	NM_031297	RNF208	ring finger protein 208

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.38	7.33e-28	GO:0007275	multicellular organismal development
1.43	1.24e-27	GO:0048731	system development
1.63	7.18e-27	GO:0007399	nervous system development
1.35	5.22e-26	GO:0032502	developmental process
1.39	1.18e-25	GO:0048856	anatomical structure development
1.76	4.29e-21	GO:0048699	generation of neurons
1.73	8.29e-21	GO:0022008	neurogenesis
1.46	1.51e-20	GO:0030154	cell differentiation
1.83	3.71e-20	GO:0030182	neuron differentiation
1.45	3.87e-20	GO:0048869	cellular developmental process
1.53	3.62e-19	GO:0009653	anatomical structure morphogenesis
1.46	1.02e-18	GO:0048513	organ development
1.65	1.17e-16	GO:0048468	cell development
1.52	3.58e-15	GO:0051239	regulation of multicellular organismal process
1.63	3.99e-15	GO:0050793	regulation of developmental process
1.22	4.40e-15	GO:0032501	multicellular organismal process
1.73	5.80e-15	GO:0045595	regulation of cell differentiation
1.33	2.85e-14	GO:0048518	positive regulation of biological process
1.82	2.46e-13	GO:0000904	cell morphogenesis involved in differentiation
1.76	3.30e-13	GO:0048666	neuron development
1.74	4.22e-13	GO:0009887	organ morphogenesis
2.02	6.05e-13	GO:0060284	regulation of cell development
1.79	9.10e-13	GO:0007417	central nervous system development
1.81	9.82e-13	GO:0031175	neuron projection development
1.85	1.13e-12	GO:0048812	neuron projection morphogenesis
1.86	1.14e-12	GO:0048667	cell morphogenesis involved in neuron differentiation
1.88	1.14e-12	GO:0007409	axonogenesis
1.64	1.30e-12	GO:2000026	regulation of multicellular organismal development
1.14	2.78e-12	GO:0065007	biological regulation
1.62	4.79e-12	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.66	5.44e-12	GO:0010628	positive regulation of gene expression
1.33	8.55e-12	GO:0048519	negative regulation of biological process
1.53	1.31e-11	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.32	1.55e-11	GO:0048522	positive regulation of cellular process
1.78	1.98e-11	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.60	2.64e-11	GO:0051173	positive regulation of nitrogen compound metabolic process
1.33	5.42e-11	GO:0048523	negative regulation of cellular process
1.66	6.99e-11	GO:0045893	positive regulation of transcription, DNA-dependent
1.93	7.33e-11	GO:0051093	negative regulation of developmental process
1.65	1.31e-10	GO:0032989	cellular component morphogenesis
1.67	1.32e-10	GO:0000902	cell morphogenesis
2.03	1.47e-10	GO:0045596	negative regulation of cell differentiation
1.62	2.62e-10	GO:0051254	positive regulation of RNA metabolic process
1.14	2.68e-10	GO:0050789	regulation of biological process
1.72	4.54e-10	GO:0048858	cell projection morphogenesis
1.84	9.59e-10	GO:0007420	brain development
1.70	1.05e-09	GO:0032990	cell part morphogenesis
1.14	1.15e-09	GO:0050794	regulation of cellular process
1.62	1.18e-09	GO:0030030	cell projection organization
1.94	3.53e-09	GO:0051960	regulation of nervous system development
1.56	3.55e-09	GO:0010557	positive regulation of macromolecule biosynthetic process
1.52	4.55e-09	GO:0031328	positive regulation of cellular biosynthetic process
1.51	5.40e-09	GO:0009891	positive regulation of biosynthetic process
1.41	5.81e-09	GO:0009893	positive regulation of metabolic process
1.42	1.38e-08	GO:0031325	positive regulation of cellular metabolic process
2.08	1.45e-08	GO:0045664	regulation of neuron differentiation
1.97	1.49e-08	GO:0050767	regulation of neurogenesis
1.33	1.55e-08	GO:0007166	cell surface receptor linked signaling pathway
1.42	2.89e-08	GO:0010604	positive regulation of macromolecule metabolic process
1.63	2.96e-08	GO:0051253	negative regulation of RNA metabolic process
1.74	3.76e-08	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.21	3.79e-08	GO:0023052	signaling
1.64	3.81e-08	GO:0045892	negative regulation of transcription, DNA-dependent
1.70	4.64e-08	GO:0007268	synaptic transmission
1.52	6.93e-08	GO:0007267	cell-cell signaling
1.48	8.51e-08	GO:0009888	tissue development
1.65	1.07e-07	GO:0019226	transmission of nerve impulse
1.65	1.07e-07	GO:0035637	multicellular organismal signaling
2.05	1.08e-07	GO:0032582	negative regulation of gene-specific transcription
1.57	2.74e-07	GO:0010629	negative regulation of gene expression
2.15	2.75e-07	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.52	3.18e-07	GO:0009790	embryo development
1.24	4.09e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.76	5.39e-07	GO:0007411	axon guidance
1.72	6.52e-07	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.52	7.58e-07	GO:0031327	negative regulation of cellular biosynthetic process
1.51	9.00e-07	GO:0009890	negative regulation of biosynthetic process
2.24	1.06e-06	GO:0010769	regulation of cell morphogenesis involved in differentiation
2.22	1.56e-06	GO:0022604	regulation of cell morphogenesis
1.41	1.70e-06	GO:0007154	cell communication
1.64	2.22e-06	GO:0032583	regulation of gene-specific transcription
1.23	3.37e-06	GO:0051171	regulation of nitrogen compound metabolic process
1.52	4.69e-06	GO:0051172	negative regulation of nitrogen compound metabolic process
1.43	4.84e-06	GO:0040011	locomotion
1.52	5.36e-06	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30	5.64e-06	GO:0023051	regulation of signaling
1.50	6.61e-06	GO:0010558	negative regulation of macromolecule biosynthetic process
1.40	7.03e-06	GO:0009605	response to external stimulus
1.18	7.98e-06	GO:0019222	regulation of metabolic process
1.25	1.01e-05	GO:0006355	regulation of transcription, DNA-dependent
1.25	1.08e-05	GO:0051252	regulation of RNA metabolic process
1.22	1.09e-05	GO:0031326	regulation of cellular biosynthetic process
1.70	1.09e-05	GO:0044057	regulation of system process
1.84	1.18e-05	GO:0048568	embryonic organ development
1.76	1.22e-05	GO:0007423	sensory organ development
1.19	1.50e-05	GO:0080090	regulation of primary metabolic process
2.47	1.74e-05	GO:0021953	central nervous system neuron differentiation
1.18	1.80e-05	GO:0031323	regulation of cellular metabolic process
1.22	2.05e-05	GO:0009889	regulation of biosynthetic process
1.27	2.34e-05	GO:0048583	regulation of response to stimulus
1.49	2.71e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.71	2.77e-05	GO:0022603	regulation of anatomical structure morphogenesis
1.64	2.86e-05	GO:0048598	embryonic morphogenesis
1.72	2.98e-05	GO:0048729	tissue morphogenesis
1.24	4.22e-05	GO:0065008	regulation of biological quality
1.65	7.49e-05	GO:0007389	pattern specification process
2.16	1.12e-04	GO:0003001	generation of a signal involved in cell-cell signaling
2.16	1.12e-04	GO:0023061	signal release
1.21	1.96e-04	GO:0010468	regulation of gene expression
1.89	2.25e-04	GO:0030900	forebrain development
1.37	2.98e-04	GO:0031324	negative regulation of cellular metabolic process
1.35	3.52e-04	GO:0009892	negative regulation of metabolic process
1.22	3.92e-04	GO:0042221	response to chemical stimulus
2.40	4.11e-04	GO:0050770	regulation of axonogenesis
1.34	4.49e-04	GO:0010646	regulation of cell communication
1.21	4.67e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.03	4.69e-04	GO:0010975	regulation of neuron projection development
1.93	5.28e-04	GO:0031344	regulation of cell projection organization
1.68	5.53e-04	GO:0061061	muscle structure development
1.49	5.77e-04	GO:0006935	chemotaxis
1.49	5.77e-04	GO:0042330	taxis
1.17	5.98e-04	GO:0007165	signal transduction
1.89	7.17e-04	GO:0006813	potassium ion transport
1.92	7.87e-04	GO:0045165	cell fate commitment
1.76	7.93e-04	GO:0043193	positive regulation of gene-specific transcription
1.90	8.11e-04	GO:0048562	embryonic organ morphogenesis
1.81	8.97e-04	GO:0048732	gland development
1.17	9.69e-04	GO:0060255	regulation of macromolecule metabolic process
2.44	9.88e-04	GO:0007269	neurotransmitter secretion
2.34	9.89e-04	GO:0010721	negative regulation of cell development
1.35	1.33e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.20	1.43e-03	GO:0010556	regulation of macromolecule biosynthetic process
2.08	1.75e-03	GO:0006836	neurotransmitter transport
1.27	2.23e-03	GO:0009966	regulation of signal transduction
2.01	2.73e-03	GO:0043583	ear development
1.49	3.48e-03	GO:0051094	positive regulation of developmental process
1.83	3.82e-03	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
1.34	4.50e-03	GO:0006351	transcription, DNA-dependent
1.49	4.59e-03	GO:0046903	secretion
2.09	4.89e-03	GO:0048839	inner ear development
1.67	5.27e-03	GO:0003002	regionalization
1.35	5.84e-03	GO:0051128	regulation of cellular component organization
1.55	7.67e-03	GO:0045597	positive regulation of cell differentiation
1.66	9.86e-03	GO:0002009	morphogenesis of an epithelium
2.15	1.04e-02	GO:0042471	ear morphogenesis
1.35	1.08e-02	GO:0007155	cell adhesion
1.35	1.08e-02	GO:0022610	biological adhesion
2.25	1.32e-02	GO:0042472	inner ear morphogenesis
2.55	1.34e-02	GO:0048663	neuron fate commitment
1.43	1.67e-02	GO:0048585	negative regulation of response to stimulus
1.30	1.88e-02	GO:0032879	regulation of localization
1.70	1.96e-02	GO:0007517	muscle organ development
1.86	2.08e-02	GO:0030799	regulation of cyclic nucleotide metabolic process
1.49	2.39e-02	GO:0060429	epithelium development
2.16	2.66e-02	GO:0048638	regulation of developmental growth
2.64	3.03e-02	GO:0046888	negative regulation of hormone secretion
1.49	3.16e-02	GO:0043009	chordate embryonic development
1.48	3.17e-02	GO:0009792	embryo development ending in birth or egg hatching
2.02	3.30e-02	GO:0001505	regulation of neurotransmitter levels
2.27	3.35e-02	GO:0048634	regulation of muscle organ development
1.36	3.38e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.70	3.47e-02	GO:0003012	muscle system process
1.67	3.59e-02	GO:0003013	circulatory system process
1.67	3.59e-02	GO:0008015	blood circulation
1.77	3.60e-02	GO:0060562	epithelial tube morphogenesis
1.53	3.88e-02	GO:0032940	secretion by cell
1.78	4.13e-02	GO:0001655	urogenital system development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.32	1.72e-11	GO:0044459	plasma membrane part
1.66	1.24e-07	GO:0045202	synapse
2.13	5.08e-07	GO:0034703	cation channel complex
1.17	5.30e-07	GO:0005886	plasma membrane
1.17	7.22e-07	GO:0071944	cell periphery
1.73	1.17e-06	GO:0044456	synapse part
1.48	5.46e-06	GO:0030054	cell junction
1.78	3.48e-05	GO:0034702	ion channel complex
2.24	4.72e-05	GO:0008076	voltage-gated potassium channel complex
2.24	4.72e-05	GO:0034705	potassium channel complex
1.30	7.53e-05	GO:0031226	intrinsic to plasma membrane
1.29	1.53e-04	GO:0005887	integral to plasma membrane
1.51	3.83e-04	GO:0043005	neuron projection
1.51	7.60e-04	GO:0031012	extracellular matrix
2.10	1.07e-03	GO:0008021	synaptic vesicle
1.32	2.55e-03	GO:0005624	membrane fraction
1.31	5.28e-03	GO:0005626	insoluble fraction
1.49	1.25e-02	GO:0005578	proteinaceous extracellular matrix
1.87	1.91e-02	GO:0019717	synaptosome
1.28	2.08e-02	GO:0042995	cell projection
1.25	2.52e-02	GO:0044421	extracellular region part
1.65	3.57e-02	GO:0030136	clathrin-coated vesicle
2.28	4.28e-02	GO:0030672	synaptic vesicle membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.92	3.67e-26	GO:0043565	sequence-specific DNA binding
1.60	6.52e-17	GO:0030528	transcription regulator activity
1.59	3.23e-16	GO:0001071	nucleic acid binding transcription factor activity
1.59	3.23e-16	GO:0003700	sequence-specific DNA binding transcription factor activity
1.92	1.34e-09	GO:0005261	cation channel activity
2.03	7.00e-09	GO:0000975	regulatory region DNA binding
2.03	7.00e-09	GO:0001067	regulatory region nucleic acid binding
2.03	7.00e-09	GO:0044212	transcription regulatory region DNA binding
2.04	1.29e-08	GO:0010843	promoter binding
2.16	1.19e-07	GO:0022843	voltage-gated cation channel activity
1.96	6.88e-07	GO:0005244	voltage-gated ion channel activity
1.96	6.88e-07	GO:0022832	voltage-gated channel activity
2.13	3.66e-06	GO:0005267	potassium channel activity
1.61	3.86e-06	GO:0022838	substrate-specific channel activity
1.70	4.08e-06	GO:0022836	gated channel activity
1.61	5.16e-06	GO:0005216	ion channel activity
1.10	9.81e-06	GO:0005515	protein binding
1.56	3.02e-05	GO:0015267	channel activity
1.56	3.56e-05	GO:0022803	passive transmembrane transporter activity
1.61	2.52e-04	GO:0016564	transcription repressor activity
2.09	4.67e-04	GO:0005249	voltage-gated potassium channel activity
1.39	7.33e-04	GO:0046983	protein dimerization activity
1.48	1.13e-03	GO:0019904	protein domain specific binding
1.56	1.38e-03	GO:0016563	transcription activator activity
1.19	2.43e-03	GO:0003677	DNA binding
1.99	6.50e-03	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
2.03	8.93e-03	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.37	1.44e-02	GO:0008324	cation transmembrane transporter activity
1.95	1.98e-02	GO:0003704	specific RNA polymerase II transcription factor activity
1.55	2.35e-02	GO:0003702	RNA polymerase II transcription factor activity
1.04	2.44e-02	GO:0005488	binding
1.30	3.54e-02	GO:0015075	ion transmembrane transporter activity
1.27	4.41e-02	GO:0022891	substrate-specific transmembrane transporter activity