Motif ID: JUN.p2

Z-value: 1.475


Transcription factors associated with JUN.p2:

Gene SymbolEntrez IDGene Name
JUN 3725 jun oncogene
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
JUNchr1_-_590208750.495.1e-02Click!
JUNBchr19_+_12763295,
chr19_+_12763285		0.312.5e-01Click!
JUNDchr19_-_182534130.224.1e-01Click!


Activity profile for motif JUN.p2.

activity profile for motif JUN.p2


Sorted Z-values histogram for motif JUN.p2

Sorted Z-values for motif JUN.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of JUN.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_-_42589543 8.120 NM_014351
 SULT4A1
sulfotransferase family 4A, member 1
chr12_-_121946581 4.736 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr12_-_121946635 4.337 NM_024667
 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr1_+_26368969 3.469 NM_015871
 ZNF593
zinc finger protein 593
chr6_+_139497933 3.404 NM_016217
 HECA
headcase homolog (Drosophila)
chr11_-_1549719 2.906 NM_004420
 DUSP8
dual specificity phosphatase 8
chr4_-_111763655 2.618 NM_000325
 PITX2
paired-like homeodomain 2
chr20_+_32610161 2.429 NM_032514
 MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr7_-_100595552 2.219 NM_003378
 VGF
VGF nerve growth factor inducible
chr10_-_131652364 2.208 EBF3
early B-cell factor 3
chr12_+_131194967 2.202 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr10_+_134060681 2.197 NM_001098637
NM_138499
 PWWP2B

PWWP domain containing 2B

chr19_+_55671600 2.184 C19orf63
chromosome 19 open reading frame 63
chr9_-_139473606 2.063 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
 NELF




nasal embryonic LHRH factor




chr19_+_55671594 2.055 C19orf63
chromosome 19 open reading frame 63
chr12_+_131194931 2.043 NM_024078
 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr19_+_55671584 2.041 C19orf63
chromosome 19 open reading frame 63
chr6_+_39868126 2.036 DAAM2
dishevelled associated activator of morphogenesis 2
chr12_-_121946561 2.031


chr19_+_50663089 2.029 NM_001114171
NM_006732
 FOSB

FBJ murine osteosarcoma viral oncogene homolog B


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
1.91 8.88e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.82 1.01e-02 GO:0072358 cardiovascular system development
1.82 1.01e-02 GO:0072359 circulatory system development
1.76 1.37e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.75 1.40e-02 GO:0051253 negative regulation of RNA metabolic process
1.66 1.17e-02 GO:0030182 neuron differentiation
1.66 4.70e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.65 5.00e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.64 3.54e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.64 3.92e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.62 3.43e-02 GO:0009890 negative regulation of biosynthetic process
1.54 3.43e-02 GO:0022008 neurogenesis
1.46 2.92e-03 GO:0009653 anatomical structure morphogenesis
1.44 4.00e-08 GO:0048731 system development
1.44 8.06e-05 GO:0030154 cell differentiation
1.41 2.83e-04 GO:0048869 cellular developmental process
1.41 3.67e-02 GO:0007399 nervous system development
1.40 3.55e-03 GO:0048513 organ development
1.39 4.77e-07 GO:0048856 anatomical structure development
1.37 4.54e-07 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.76 6.84e-03 GO:0030017 sarcomere
2.66 3.33e-03 GO:0030016 myofibril
2.62 3.03e-03 GO:0043292 contractile fiber
2.51 2.09e-02 GO:0044449 contractile fiber part

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
3.59 4.65e-02 GO:0008307 structural constituent of muscle
2.09 6.81e-04 GO:0008134 transcription factor binding
1.93 1.58e-07 GO:0043565 sequence-specific DNA binding
1.80 1.09e-08 GO:0001071 nucleic acid binding transcription factor activity
1.80 1.09e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.68 4.23e-06 GO:0030528 transcription regulator activity
1.15 1.63e-03 GO:0005515 protein binding
1.09 8.92e-04 GO:0005488 binding