Motif ID: TFCP2.p2

Z-value: 3.054


Transcription factors associated with TFCP2.p2:

Gene SymbolEntrez IDGene Name
TFCP2 7024 transcription factor CP2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFCP2chr12_-_498528580.552.9e-02Click!


Activity profile for motif TFCP2.p2.

activity profile for motif TFCP2.p2


Sorted Z-values histogram for motif TFCP2.p2

Sorted Z-values for motif TFCP2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFCP2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_1518875 4.111 NM_001174118
NM_203304
 MEX3D

mex-3 homolog D (C. elegans)

chr17_+_56832255 3.931 TBX2
T-box 2
chr17_+_56831951 3.921 NM_005994
 TBX2
T-box 2
chr2_+_238712101 3.897 NM_198582
 KLHL30
kelch-like 30 (Drosophila)
chr17_+_56832492 3.635 TBX2
T-box 2
chr19_+_38377329 3.088 NM_002333
 LRP3
low density lipoprotein receptor-related protein 3
chr17_-_71023048 2.976 CASKIN2
CASK interacting protein 2
chr1_-_16355013 2.937 NM_004431
 EPHA2
EPH receptor A2
chr17_-_71023221 2.818 NM_020753
 CASKIN2
CASK interacting protein 2
chr19_+_38376980 2.776 LRP3
low density lipoprotein receptor-related protein 3
chr1_+_200124412 2.759 NM_198149
 SHISA4
shisa homolog 4 (Xenopus laevis)
chr11_+_76455574 2.738 NM_004055
 CAPN5
calpain 5
chr11_+_64838882 2.580 NM_006779
 CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr15_-_37999717 2.514 GPR176
G protein-coupled receptor 176
chr1_+_200124620 2.403 SHISA4
shisa homolog 4 (Xenopus laevis)
chr3_-_121652183 2.355 NM_007085
 FSTL1
follistatin-like 1
chr14_-_104515738 2.305 NM_138420
 AHNAK2
AHNAK nucleoprotein 2
chr9_-_139235595 2.248 NM_031297
 RNF208
ring finger protein 208
chr14_+_92188546 2.241 RIN3
Ras and Rab interactor 3
chr21_+_46226072 2.227 NM_001848
 COL6A1
collagen, type VI, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 93 entries
enrichment   p-value GO term description
2.23 1.28e-02 GO:0048638 regulation of developmental growth
2.17 2.63e-02 GO:0022612 gland morphogenesis
1.90 1.59e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.88 2.05e-02 GO:0022604 regulation of cell morphogenesis
1.86 8.31e-03 GO:0034330 cell junction organization
1.82 3.98e-07 GO:0022603 regulation of anatomical structure morphogenesis
1.78 1.01e-04 GO:0046578 regulation of Ras protein signal transduction
1.72 3.31e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.72 1.62e-02 GO:0048732 gland development
1.67 1.39e-06 GO:0007409 axonogenesis
1.67 8.91e-05 GO:0007411 axon guidance
1.67 7.10e-04 GO:0001944 vasculature development
1.67 4.50e-02 GO:0045664 regulation of neuron differentiation
1.66 3.60e-03 GO:0030334 regulation of cell migration
1.65 2.18e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.65 2.34e-03 GO:0051960 regulation of nervous system development
1.64 5.46e-05 GO:0051056 regulation of small GTPase mediated signal transduction
1.64 5.84e-04 GO:0060284 regulation of cell development
1.64 6.24e-03 GO:2000145 regulation of cell motility
1.63 4.93e-07 GO:0000904 cell morphogenesis involved in differentiation

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.79 3.23e-03 GO:0005912 adherens junction
1.74 4.10e-03 GO:0070161 anchoring junction
1.65 2.93e-06 GO:0031012 extracellular matrix
1.63 7.26e-05 GO:0005578 proteinaceous extracellular matrix
1.43 2.25e-04 GO:0030054 cell junction
1.32 2.76e-04 GO:0044421 extracellular region part
1.22 1.41e-04 GO:0044459 plasma membrane part
1.17 2.99e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.07 3.00e-02 GO:0005089 Rho guanyl-nucleotide exchange factor activity
1.94 3.64e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.62 5.08e-04 GO:0005083 small GTPase regulator activity
1.54 2.39e-02 GO:0032403 protein complex binding
1.54 4.44e-02 GO:0005096 GTPase activator activity
1.52 1.29e-04 GO:0030695 GTPase regulator activity
1.49 3.90e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.42 1.42e-04 GO:0043565 sequence-specific DNA binding
1.30 4.54e-02 GO:0042802 identical protein binding
1.28 9.96e-03 GO:0030528 transcription regulator activity
1.28 1.40e-02 GO:0001071 nucleic acid binding transcription factor activity
1.28 1.40e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.11 1.34e-05 GO:0005515 protein binding
1.05 2.69e-03 GO:0005488 binding