Motif ID: STAT1,3.p3

Z-value: 0.821


Transcription factors associated with STAT1,3.p3:

Gene SymbolEntrez IDGene Name
STAT1 6772 signal transducer and activator of transcription 1, 91kDa
STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT3chr17_-_37794017-0.302.6e-01Click!
STAT1chr2_-_191587127-0.146.1e-01Click!


Activity profile for motif STAT1,3.p3.

activity profile for motif STAT1,3.p3


Sorted Z-values histogram for motif STAT1,3.p3

Sorted Z-values for motif STAT1,3.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT1,3.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_54072969 1.635 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr11_-_121492010 1.064 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr16_-_65818401 0.896 NM_001004055
LRRC29
leucine rich repeat containing 29
chr19_-_49644470 0.892 NM_014518
ZNF229
zinc finger protein 229
chr10_+_90741024 0.843 FAS
Fas (TNF receptor superfamily, member 6)
chr19_-_39859997 0.826


chr19_+_39860398 0.771 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr1_-_151788341 0.690 NM_002960
S100A3
S100 calcium binding protein A3
chrX_+_106030049 0.578 NM_001171092
CLDN2
claudin 2
chr22_-_29833484 0.561 NM_080430
SELM
selenoprotein M
chr19_-_60566419 0.560 NM_001145402
FAM71E2
family with sequence similarity 71, member E2
chrX_-_106033202 0.550 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr17_-_39333490 0.525 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr17_-_8020332 0.507 NM_032354
NM_183065
TMEM107

transmembrane protein 107

chr16_-_73012740 0.481 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr4_+_120029426 0.472 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr22_-_29866339 0.465 NM_015715
PLA2G3
phospholipase A2, group III
chr10_-_90740935 0.449 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr16_-_65818221 0.411 NM_012163
LRRC29
leucine rich repeat containing 29
chr11_+_113672378 0.398 NNMT
nicotinamide N-methyltransferase
chr8_-_143856640 0.396 NM_023946
NM_177457
LYNX1

Ly6/neurotoxin 1

chr19_+_49248003 0.394 NM_013361
ZNF223
zinc finger protein 223
chr2_-_70042900 0.393 NM_152792
ASPRV1
aspartic peptidase, retroviral-like 1
chr19_+_17391856 0.376 NM_138401
FAM125A
family with sequence similarity 125, member A
chr5_+_149867866 0.376 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr5_-_133734616 0.361 CDKL3
cyclin-dependent kinase-like 3
chr16_-_66075216 0.360 NM_001138
AGRP
agouti related protein homolog (mouse)
chr19_+_49309350 0.358 NM_013362
ZNF225
zinc finger protein 225
chr1_-_143706265 0.344 PDE4DIP
phosphodiesterase 4D interacting protein
chr11_-_64247230 0.342 NM_015080
NM_138732
NRXN2

neurexin 2

chr3_-_172109119 0.328 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr1_-_143706300 0.326 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr1_-_6502655 0.322 NM_198681
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_+_49147219 0.316 NM_013359
ZNF221
zinc finger protein 221
chr5_+_139924224 0.303 SLC35A4
solute carrier family 35, member A4
chr19_+_53559468 0.301 NM_012451
SYNGR4
synaptogyrin 4
chr19_+_49198916 0.299 NM_006300
ZNF230
zinc finger protein 230
chr2_-_113310796 0.295 NM_000576
IL1B
interleukin 1, beta
chr11_+_113672407 0.294 NNMT
nicotinamide N-methyltransferase
chr17_+_7402788 0.281 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_4902144 0.277 NM_001005237
OR51G1
olfactory receptor, family 51, subfamily G, member 1
chr22_+_34374358 0.274 NM_030641
APOL6
apolipoprotein L, 6
chr12_-_119172339 0.269 NM_025157
PXN
paxillin
chr17_+_9420668 0.268 NM_001080556
NM_145054
WDR16

WD repeat domain 16

chr22_+_34374421 0.262 APOL6
apolipoprotein L, 6
chrX_-_100434700 0.260 NM_024885
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr15_-_73719546 0.238 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr9_+_5440455 0.234 NM_014143
CD274
CD274 molecule
chr19_-_61596681 0.230 NM_144690
ZNF582
zinc finger protein 582
chr19_-_844215 0.229 NM_005481
MED16
mediator complex subunit 16
chr19_-_4853878 0.228 NM_001080523
ARRDC5
arrestin domain containing 5
chr14_+_23905984 0.227 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr1_+_891739 0.227 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr19_+_49268106 0.222 NM_001037813
ZNF284
zinc finger protein 284
chr11_+_129823667 0.220 NM_139055
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr11_-_64459910 0.216 NM_130769
GPHA2
glycoprotein hormone alpha 2
chr19_+_54669629 0.216 FLT3LG
fms-related tyrosine kinase 3 ligand
chr19_-_844184 0.213 MED16
mediator complex subunit 16
chr4_+_126457016 0.209 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr1_-_16411690 0.206 NM_153213
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr1_+_10457579 0.205 NM_004565
PEX14
peroxisomal biogenesis factor 14
chr19_+_17391841 0.197 FAM125A
family with sequence similarity 125, member A
chr19_-_49500966 0.196 NM_004234
ZNF235
zinc finger protein 235
chr12_-_74711642 0.192 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr11_+_61204392 0.188 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr10_+_91142301 0.182 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr13_+_97856148 0.179


chr6_-_132764257 0.177 NM_015529
MOXD1
monooxygenase, DBH-like 1
chr1_+_22842704 0.173 NM_001114101
NM_172369
C1QC

complement component 1, q subcomponent, C chain

chr20_-_42713663 0.170 ADA
adenosine deaminase
chr19_+_3713671 0.168 MRPL54
mitochondrial ribosomal protein L54
chr1_-_201422436 0.163 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr19_-_4782711 0.154 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr4_+_41235077 0.154 LIMCH1
LIM and calponin homology domains 1
chr1_-_157313179 0.153 NM_004833
AIM2
absent in melanoma 2
chr22_-_39966801 0.152 NM_138481
CHADL
chondroadherin-like
chr15_-_70863166 0.150 NM_031284
ADPGK
ADP-dependent glucokinase
chr19_-_6688603 0.150 NM_001080452
GPR108
G protein-coupled receptor 108
chr1_+_34405070 0.148 NM_032884
C1orf94
chromosome 1 open reading frame 94
chr9_-_129226312 0.146


chr16_-_30705707 0.146 NM_001080417
ZNF629
zinc finger protein 629
chr19_-_43412152 0.145 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr16_-_3049336 0.144


chr12_-_8271460 0.144 NM_018088
FAM90A1
family with sequence similarity 90, member A1
chr20_+_60906605 0.141 NM_007346
OGFR
opioid growth factor receptor
chr1_-_201422533 0.139 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr15_+_30797466 0.138 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr2_-_85948287 0.138 NM_001042437
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr16_+_65818511 0.135 NM_014187
TMEM208
transmembrane protein 208
chr15_-_70863110 0.133 ADPGK
ADP-dependent glucokinase
chr1_-_201422450 0.133 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_+_112811562 0.132 NM_004185
WNT2B
wingless-type MMTV integration site family, member 2B
chr15_+_88609837 0.132 NM_001033088
NGRN
neugrin, neurite outgrowth associated
chr17_-_73867748 0.132 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr19_-_49309102 0.131 LOC100379224
hypothetical LOC100379224
chr6_+_139391511 0.131 NM_021243
C6orf115
chromosome 6 open reading frame 115
chr3_-_172109075 0.128 EIF5A2
eukaryotic translation initiation factor 5A2
chrX_+_46318135 0.127 NM_019886
CHST7
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr14_+_99309688 0.126 EML1
echinoderm microtubule associated protein like 1
chr3_-_135575925 0.125 NM_016201
AMOTL2
angiomotin like 2
chr10_+_90552466 0.123 NM_001128215
LIPM
lipase, family member M
chr1_-_145712107 0.123 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr8_+_86344984 0.121 CA13
carbonic anhydrase XIII
chr14_+_73027423 0.121 C14orf169
chromosome 14 open reading frame 169
chr1_-_201422368 0.120 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr3_+_116824840 0.116 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr9_+_135994734 0.116 NM_052821
WDR5
WD repeat domain 5
chr11_-_128567302 0.116 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr14_+_73027410 0.116 C14orf169
chromosome 14 open reading frame 169
chr22_+_19191886 0.113 MED15
mediator complex subunit 15
chr14_+_73027438 0.113 C14orf169
chromosome 14 open reading frame 169
chr1_+_148137778 0.111 NM_016074
BOLA1
bolA homolog 1 (E. coli)
chr6_+_54819527 0.111 NM_001010872
FAM83B
family with sequence similarity 83, member B
chr15_-_70863115 0.108 ADPGK
ADP-dependent glucokinase
chr19_-_63775901 0.108 MZF1
myeloid zinc finger 1
chr11_+_57554977 0.108 NM_001005186
OR6Q1
olfactory receptor, family 6, subfamily Q, member 1
chr17_+_71586857 0.107 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr9_-_23811477 0.107 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr8_+_36760999 0.106 NM_001031836
KCNU1
potassium channel, subfamily U, member 1
chr14_+_98247702 0.105 NM_182560
C14orf177
chromosome 14 open reading frame 177
chr22_+_19191859 0.105 MED15
mediator complex subunit 15
chr12_+_48792015 0.103 NM_032901
C12orf62
chromosome 12 open reading frame 62
chr10_-_61139328 0.100 NM_194298
LOC100129721
SLC16A9
hypothetical protein LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr3_-_52839727 0.099 NM_001166449
NM_002218
ITIH4

inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)

chr19_+_61798434 0.098 NM_021216
ZNF71
zinc finger protein 71
chr20_+_35406497 0.097 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr15_-_70863124 0.096 ADPGK
ADP-dependent glucokinase
chr13_+_104916565 0.096 NM_001161812
DAOA
D-amino acid oxidase activator
chr11_-_118471385 0.096 NM_002105
H2AFX
H2A histone family, member X
chr5_-_139924013 0.096 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr17_+_39778016 0.096 NM_002087
GRN
granulin
chr15_-_41409979 0.096 NM_014793
LCMT2
leucine carboxyl methyltransferase 2
chr11_+_32068990 0.096 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr14_-_104718565 0.095 NM_177533
NUDT14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr3_-_121065112 0.094


chr10_+_85994788 0.094 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr17_+_57811645 0.092 NM_173503
EFCAB3
EF-hand calcium binding domain 3
chr19_-_3935152 0.091 EEF2
eukaryotic translation elongation factor 2
chrX_+_102749489 0.091 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr20_-_47618059 0.091 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr3_-_171070314 0.089 NM_024727
LRRC31
leucine rich repeat containing 31
chr14_-_91483757 0.088 NM_006329
FBLN5
fibulin 5
chr1_-_201422490 0.087 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr22_+_19191875 0.085 MED15
mediator complex subunit 15
chr2_+_235525355 0.085 NM_014521
SH3BP4
SH3-domain binding protein 4
chr15_-_70863078 0.083 ADPGK
ADP-dependent glucokinase
chr16_-_1410710 0.082 C16orf91
chromosome 16 open reading frame 91
chr8_-_8276598 0.081 NM_001080826
SGK223
homolog of rat pragma of Rnd2
chr8_+_1759502 0.080 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr14_+_73027361 0.080 NM_024644
C14orf169
chromosome 14 open reading frame 169
chr19_+_49290319 0.080 NM_013398
ZNF224
zinc finger protein 224
chr22_+_19191884 0.080 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr5_+_109052984 0.080


chr8_-_134184491 0.079 NM_001045556
NM_001045557
SLA

Src-like-adaptor

chr13_+_24844084 0.079 NM_016529
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr6_+_139391570 0.079 C6orf115
chromosome 6 open reading frame 115
chr2_+_218698242 0.079 NM_001168298
CXCR2
chemokine (C-X-C motif) receptor 2
chr19_+_3713650 0.078 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr12_+_11694172 0.078 ETV6
ets variant 6
chrX_-_62891066 0.078 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr8_+_11388918 0.074 NM_001715
BLK
B lymphoid tyrosine kinase
chr5_-_139924229 0.071 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr11_+_32069183 0.071 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr2_+_149603226 0.071 NM_177964
LYPD6B
LY6/PLAUR domain containing 6B
chr12_-_107238568 0.070 NM_001142345
CMKLR1
chemokine-like receptor 1
chr3_+_130081210 0.070 ACAD9
acyl-CoA dehydrogenase family, member 9
chr11_-_605920 0.070 IRF7
interferon regulatory factor 7
chr12_-_6355165 0.070 NM_001038
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr3_+_48456667 0.069 NM_015933
CCDC72
coiled-coil domain containing 72
chr8_-_18710575 0.067 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr11_+_834111 0.067 TSPAN4
tetraspanin 4
chr12_-_41164052 0.067 NM_001144882
NM_001144883
PRICKLE1

prickle homolog 1 (Drosophila)

chr20_-_5982617 0.066 NM_152611
LRRN4
leucine rich repeat neuronal 4
chr3_-_61212076 0.065 NM_001166243
NM_002012
FHIT

fragile histidine triad gene

chr7_-_87774130 0.065 NM_024636
STEAP4
STEAP family member 4
chr5_-_138753443 0.064 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr17_-_70480345 0.062


chr10_+_95838801 0.062 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr12_+_12115668 0.062 NM_030766
NM_138722
BCL2L14

BCL2-like 14 (apoptosis facilitator)

chr11_-_62218759 0.061 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_-_42402973 0.061 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr8_-_143856179 0.061 LYNX1
Ly6/neurotoxin 1
chr19_+_54669283 0.060 NM_001459
FLT3LG
fms-related tyrosine kinase 3 ligand
chr7_-_148788799 0.060 NM_015694
ZNF777
zinc finger protein 777
chr19_-_6688589 0.060 GPR108
G protein-coupled receptor 108
chr11_-_118471313 0.059 H2AFX
H2A histone family, member X
chr2_+_165858586 0.059 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr19_-_3577774 0.058 C19orf29
chromosome 19 open reading frame 29
chr5_+_109052945 0.057 MAN2A1
mannosidase, alpha, class 2A, member 1
chr16_+_4546491 0.057 NM_001145011
LOC342346
hypothetical protein LOC342346
chr1_-_52272020 0.057 NM_138417
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr14_-_87862676 0.056 KCNK10
potassium channel, subfamily K, member 10
chr11_-_7684516 0.056 NM_198185
OVCH2
ovochymase 2 (gene/pseudogene)
chr22_+_19191898 0.055 MED15
mediator complex subunit 15
chr11_+_6898780 0.055 NM_001004684
OR2D3
olfactory receptor, family 2, subfamily D, member 3
chr1_-_153213483 0.054 NM_001130041
NM_003029
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr12_+_15017222 0.054 NM_006205
PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr19_-_6688558 0.053 GPR108
G protein-coupled receptor 108
chr1_-_153213454 0.052 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr1_+_35020425 0.051 NM_001005752
GJB3
gap junction protein, beta 3, 31kDa

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.46 2.89e-02 GO:0043167 ion binding