Motif ID: NFKB1_REL_RELA.p2

Z-value: 1.272


Transcription factors associated with NFKB1_REL_RELA.p2:

Gene SymbolEntrez IDGene Name
NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
REL 5966 v-rel reticuloendotheliosis viral oncogene homolog (avian)
RELA 5970 v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFKB1chr4_+_1036418540.639.5e-03Click!
RELAchr11_-_651828010.411.2e-01Click!
RELchr2_+_609622790.097.4e-01Click!


Activity profile for motif NFKB1_REL_RELA.p2.

activity profile for motif NFKB1_REL_RELA.p2


Sorted Z-values histogram for motif NFKB1_REL_RELA.p2

Sorted Z-values for motif NFKB1_REL_RELA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFKB1_REL_RELA.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_4180494 1.635 NM_005755
 EBI3
Epstein-Barr virus induced 3
chr14_-_95250155 1.487 NM_001098725
NM_021966
 TCL1A

T-cell leukemia/lymphoma 1A

chr19_+_50196526 1.303 NM_006509
 RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr10_+_12431714 1.224 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr10_+_104145421 1.128 NM_002502
 NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr8_-_70909754 1.080 NM_030958
 SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr17_-_16816113 1.041 NM_012452
 TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr2_+_219453487 1.022 NM_025216
 WNT10A
wingless-type MMTV integration site family, member 10A
chr10_+_104144218 1.016 NM_001077493
NM_001077494
 NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr22_-_35875890 0.958 NM_000878
 IL2RB
interleukin 2 receptor, beta
chr16_+_84490267 0.945 NM_002163
 IRF8
interferon regulatory factor 8
chr5_+_10617431 0.924 NM_001164440
 ANKRD33B
ankyrin repeat domain 33B
chr19_+_3087026 0.911 NM_002068
 GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr19_-_6542012 0.905 CD70
CD70 molecule
chr1_-_24386324 0.870 NM_170743
NM_173064
NM_173065
 IL28RA


interleukin 28 receptor, alpha (interferon, lambda receptor)


chr19_-_7672978 0.863 NM_002002
 FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr2_-_162883062 0.851 NM_022168
 IFIH1
interferon induced with helicase C domain 1
chr11_+_120828058 0.846 NM_003105
 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr9_-_139235595 0.834 NM_031297
 RNF208
ring finger protein 208
chr19_-_17819773 0.829 JAK3
Janus kinase 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
2.17 1.03e-02 GO:0051251 positive regulation of lymphocyte activation
2.16 8.56e-03 GO:0045088 regulation of innate immune response
2.13 1.40e-03 GO:0051249 regulation of lymphocyte activation
2.07 2.42e-02 GO:0002696 positive regulation of leukocyte activation
2.04 3.68e-02 GO:0050867 positive regulation of cell activation
1.97 1.05e-02 GO:0002694 regulation of leukocyte activation
1.97 3.24e-02 GO:0071345 cellular response to cytokine stimulus
1.94 1.43e-02 GO:0050865 regulation of cell activation
1.80 2.27e-02 GO:0031347 regulation of defense response
1.76 1.41e-02 GO:0045087 innate immune response
1.74 7.32e-07 GO:0006955 immune response
1.72 6.22e-03 GO:0002684 positive regulation of immune system process
1.67 8.57e-05 GO:0002682 regulation of immune system process
1.53 5.37e-06 GO:0002376 immune system process
1.52 3.75e-02 GO:0045595 regulation of cell differentiation
1.51 7.72e-03 GO:0006952 defense response
1.43 5.83e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.40 3.31e-03 GO:0035556 intracellular signal transduction
1.39 2.00e-02 GO:0009893 positive regulation of metabolic process
1.38 5.95e-03 GO:0009966 regulation of signal transduction

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
3.29 3.24e-02 GO:0032587 ruffle membrane

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
3.51 6.03e-03 GO:0003823 antigen binding
1.12 4.25e-03 GO:0005515 protein binding