Motif ID: LEF1_TCF7_TCF7L1,2.p2

Z-value: 1.267


Transcription factors associated with LEF1_TCF7_TCF7L1,2.p2:

Gene SymbolEntrez IDGene Name
LEF1 51176 lymphoid enhancer-binding factor 1
TCF7 6932 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 83439 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 6934 transcription factor 7-like 2 (T-cell specific, HMG-box)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF7L2chr10_+_1146999530.514.5e-02Click!
TCF7chr5_+_133479196-0.467.6e-02Click!
LEF1chr4_-_109308893-0.302.7e-01Click!
TCF7L1chr2_+_852138840.107.2e-01Click!


Activity profile for motif LEF1_TCF7_TCF7L1,2.p2.

activity profile for motif LEF1_TCF7_TCF7L1,2.p2


Sorted Z-values histogram for motif LEF1_TCF7_TCF7L1,2.p2

Sorted Z-values for motif LEF1_TCF7_TCF7L1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LEF1_TCF7_TCF7L1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_91632525 1.153 NM_001161528
 LOC401387
leucine-rich repeat and death domain-containing protein
chr4_-_187114407 1.093 SORBS2
sorbin and SH3 domain containing 2
chr6_-_128883125 0.987 NM_002844
NM_001135648
 PTPRK

protein tyrosine phosphatase, receptor type, K

chr20_-_13919256 0.943 NM_025229
 SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr14_-_22521544 0.912 NM_032876
 JUB
jub, ajuba homolog (Xenopus laevis)
chr2_+_69093641 0.905 NM_018153
NM_032208
NM_053034
 ANTXR1


anthrax toxin receptor 1


chr7_-_27186400 0.845 NM_153715
 HOXA10
homeobox A10
chr2_+_11597530 0.792 NM_148903
 GREB1
growth regulation by estrogen in breast cancer 1
chr1_-_116184846 0.786 NM_001111061
 NHLH2
nescient helix loop helix 2
chr2_+_171280046 0.784 NM_001003845
 SP5
Sp5 transcription factor
chr10_+_53744043 0.777 NM_012242
 DKK1
dickkopf homolog 1 (Xenopus laevis)
chr3_+_134239906 0.771 TMEM108
transmembrane protein 108
chr10_+_114699953 0.748 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
 TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr2_+_11600287 0.729 NM_033090
 GREB1
growth regulation by estrogen in breast cancer 1
chr7_-_19778928 0.711 NM_152774
 TMEM196
transmembrane protein 196
chr17_-_36376663 0.704 NM_213656
 KRT39
keratin 39
chr8_+_22075112 0.698 NM_001172357
NM_001172410
NM_003018
 SFTPC


surfactant protein C


chr8_-_121892877 0.696 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr2_+_204509698 0.678 NM_012092
 ICOS
inducible T-cell co-stimulator
chrX_-_105169370 0.674 NM_000354
 SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.