Motif ID: TCF4_dimer.p2

Z-value: 1.109


Transcription factors associated with TCF4_dimer.p2:

Gene SymbolEntrez IDGene Name
TCF4 6925 transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF4chr18_-_514063590.495.2e-02Click!


Activity profile for motif TCF4_dimer.p2.

activity profile for motif TCF4_dimer.p2


Sorted Z-values histogram for motif TCF4_dimer.p2

Sorted Z-values for motif TCF4_dimer.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF4_dimer.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_43446937 4.416 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_43447078 4.328 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_18655487 4.220 CRTC1
CREB regulated transcription coactivator 1
chr19_+_43447262 3.937 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr9_-_130980359 3.540 NM_203434
 IER5L
immediate early response 5-like
chr1_+_149750485 3.155 NM_020770
 CGN
cingulin
chr2_+_85834111 3.116 NM_032827
 ATOH8
atonal homolog 8 (Drosophila)
chr1_+_201364050 3.052 ADORA1
adenosine A1 receptor
chr8_-_49996353 3.008 NM_003068
 SNAI2
snail homolog 2 (Drosophila)
chr1_-_27211913 2.987 NM_052943
 FAM46B
family with sequence similarity 46, member B
chr3_-_87122936 2.819 NM_016206
 VGLL3
vestigial like 3 (Drosophila)
chr14_+_101097440 2.755 NM_001362
 DIO3
deiodinase, iodothyronine, type III
chr19_+_18655483 2.744 CRTC1
CREB regulated transcription coactivator 1
chr2_-_241408296 2.676 NM_004321
 KIF1A
kinesin family member 1A
chr5_+_140844810 2.596 NM_018928
NM_032406
 PCDHGC4

protocadherin gamma subfamily C, 4

chr11_+_60391590 2.587 NM_207341
 ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr1_-_231498081 2.498 NM_014801
 PCNXL2
pecanex-like 2 (Drosophila)
chr9_-_130980302 2.483 IER5L
immediate early response 5-like
chr4_+_54660954 2.473 NM_133267
 GSX2
GS homeobox 2
chr22_+_20068039 2.439 NM_001128635
 RIMBP3B
RIMS binding protein 3B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 63 entries
enrichment   p-value GO term description
1.77 1.47e-02 GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger
1.64 4.02e-04 GO:0007517 muscle organ development
1.60 2.30e-02 GO:0006813 potassium ion transport
1.57 1.41e-02 GO:0003012 muscle system process
1.54 2.32e-05 GO:0007411 axon guidance
1.54 3.00e-04 GO:0061061 muscle structure development
1.53 3.54e-02 GO:0048732 gland development
1.45 1.33e-04 GO:0007409 axonogenesis
1.44 1.44e-08 GO:0030182 neuron differentiation
1.44 3.58e-02 GO:0007423 sensory organ development
1.43 3.37e-05 GO:0000904 cell morphogenesis involved in differentiation
1.43 2.23e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.42 5.02e-04 GO:0048812 neuron projection morphogenesis
1.42 3.08e-02 GO:0060284 regulation of cell development
1.41 2.13e-10 GO:0048468 cell development
1.41 1.69e-05 GO:0048666 neuron development
1.41 2.35e-02 GO:0044057 regulation of system process
1.40 1.15e-07 GO:0007155 cell adhesion
1.40 1.15e-07 GO:0022610 biological adhesion
1.40 3.30e-04 GO:0007417 central nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
2.17 2.73e-07 GO:0045095 keratin filament
2.12 3.79e-02 GO:0005581 collagen
2.02 1.30e-02 GO:0043197 dendritic spine
1.94 3.62e-02 GO:0044309 neuron spine
1.83 1.42e-02 GO:0005604 basement membrane
1.81 1.00e-04 GO:0044420 extracellular matrix part
1.78 9.69e-05 GO:0043292 contractile fiber
1.78 2.72e-04 GO:0044449 contractile fiber part
1.78 3.18e-02 GO:0042383 sarcolemma
1.77 2.10e-03 GO:0030017 sarcomere
1.76 3.25e-04 GO:0030016 myofibril
1.72 1.05e-11 GO:0005578 proteinaceous extracellular matrix
1.66 6.09e-12 GO:0031012 extracellular matrix
1.58 2.29e-03 GO:0005882 intermediate filament
1.53 1.05e-03 GO:0034702 ion channel complex
1.53 3.18e-03 GO:0045111 intermediate filament cytoskeleton
1.50 2.62e-02 GO:0043025 neuronal cell body
1.38 3.07e-02 GO:0044456 synapse part
1.35 1.49e-09 GO:0044421 extracellular region part
1.35 6.23e-03 GO:0045202 synapse

Gene overrepresentation in function category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
2.18 4.94e-03 GO:0008307 structural constituent of muscle
1.99 1.04e-04 GO:0005201 extracellular matrix structural constituent
1.71 1.40e-03 GO:0005267 potassium channel activity
1.61 2.97e-02 GO:0015276 ligand-gated ion channel activity
1.61 2.97e-02 GO:0022834 ligand-gated channel activity
1.47 1.95e-03 GO:0005261 cation channel activity
1.46 5.73e-04 GO:0022836 gated channel activity
1.42 1.31e-04 GO:0022803 passive transmembrane transporter activity
1.42 1.89e-04 GO:0015267 channel activity
1.42 2.94e-04 GO:0005216 ion channel activity
1.42 3.06e-04 GO:0022838 substrate-specific channel activity
1.37 3.21e-02 GO:0003779 actin binding
1.34 7.71e-03 GO:0030695 GTPase regulator activity
1.33 1.23e-04 GO:0043565 sequence-specific DNA binding
1.33 7.72e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.30 3.31e-03 GO:0005198 structural molecule activity
1.27 1.30e-02 GO:0005509 calcium ion binding
1.26 9.78e-03 GO:0015075 ion transmembrane transporter activity
1.25 1.77e-03 GO:0022857 transmembrane transporter activity
1.23 1.51e-02 GO:0022891 substrate-specific transmembrane transporter activity