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Motif ID: EN1,2.p2

Z-value: 1.511

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_50318801	2.470		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr2_+_234265059	2.211	NM_205862	UGT1A6	UDP glucuronosyltransferase 1 family, polypeptide A6
chr2_+_68855436	2.123	NM_001166276 NM_014882	ARHGAP25	Rho GTPase activating protein 25
chr2_+_102401580	2.072	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr22_+_38627031	2.025	NM_004810	GRAP2	GRB2-related adaptor protein 2
chr11_+_123639909	2.011	NM_001005198	OR8G5	olfactory receptor, family 8, subfamily G, member 5
chr16_-_20271530	1.954	NM_001008389 NM_003361	UMOD	uromodulin
chr2_-_158008763	1.935	NM_004288	CYTIP	cytohesin 1 interacting protein
chr17_-_36928604	1.898	NM_002275	KRT15	keratin 15
chr1_+_169421011	1.889	NM_001460	FMO2	flavin containing monooxygenase 2 (non-functional)
chr1_+_159032551	1.854	NM_001033667 NM_002348	LY9	lymphocyte antigen 9
chr11_+_59979857	1.799	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr13_+_112349358	1.764	NM_207440	C13orf35	chromosome 13 open reading frame 35
chr3_-_184756101	1.709	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chr16_-_79811475	1.647	NM_001076780 NM_052892	PKD1L2	polycystic kidney disease 1-like 2
chr6_+_32515596	1.640	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr2_+_234333653	1.571	NM_000463	UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1
chr6_+_160247962	1.568	NM_002377	MAS1	MAS1 oncogene
chr6_+_28601767	1.567	NM_001509 NM_003996	GPX5	glutathione peroxidase 5 (epididymal androgen-related protein)
chr1_+_246635918	1.566	NM_030904	OR2T1	olfactory receptor, family 2, subfamily T, member 1
chr1_+_173111306	1.540	NM_001035230	RABGAP1L	RAB GTPase activating protein 1-like
chr4_+_71235259	1.510	NM_033122	CABS1	calcium-binding protein, spermatid-specific 1
chr10_-_48036698	1.495	NM_016204	GDF2	growth differentiation factor 2
chr9_-_34719463	1.495	NM_001141917	C9orf144B	transmembrane protein C9orf144B
chr14_+_75907442	1.485	NM_004452	ESRRB	estrogen-related receptor beta
chr7_+_149104063	1.474	NM_198455	SSPO	SCO-spondin homolog (Bos taurus)
chr4_-_80466177	1.375	NM_032693	NAA11	N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr11_+_55617328	1.363	NM_001003750	OR8I2	olfactory receptor, family 8, subfamily I, member 2
chr17_+_41278035	1.356	NM_175882	IMP5	intramembrane protease 5
chr10_-_98021144	1.326	NM_001114094 NM_013314	BLNK	B-cell linker
chr6_-_2580296	1.289	NM_152554	C6orf195	chromosome 6 open reading frame 195
chr18_+_27210737	1.278	NM_001134453 NM_177986	DSG4	desmoglein 4
chrX_+_65152004	1.269
chr4_-_47831002	1.268	NM_003328	TXK	TXK tyrosine kinase
chr15_-_78050515	1.255	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr3_+_99733432	1.246	NM_005290	GPR15	G protein-coupled receptor 15
chr17_-_64649608	1.212	NM_080284	ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6
chr3_+_171022403	1.207	NM_001080460	LRRIQ4	leucine-rich repeats and IQ motif containing 4
chr6_-_33085290	1.204		HLA-DOA	major histocompatibility complex, class II, DO alpha
chr17_+_43165608	1.195	NM_013351	TBX21	T-box 21
chr2_-_142605739	1.180	NM_018557	LRP1B	low density lipoprotein receptor-related protein 1B
chr1_+_246591505	1.170	NM_001004696	OR2T4	olfactory receptor, family 2, subfamily T, member 4
chr6_-_32121784	1.154	NM_032470	TNXB	tenascin XB
chr4_-_38710376	1.133	NM_024943	TMEM156	transmembrane protein 156
chr6_-_30188845	1.093	NM_007028	TRIM31	tripartite motif containing 31
chr1_+_159943385	1.091	NM_001184866 NM_001184867 NM_001184870 NM_001184871 NM_001184872 NM_001184873 NM_032738	FCRLA	Fc receptor-like A
chr17_-_31441390	1.089	NM_002983	CCL3	chemokine (C-C motif) ligand 3
chrX_+_50670474	1.069	NM_005448	BMP15	bone morphogenetic protein 15
chr1_-_150353179	1.067	NM_007113	TCHH	trichohyalin
chr14_+_87541220	1.065	NM_003608	GPR65	G protein-coupled receptor 65
chr11_+_5367182	1.049	NM_001004756	OR51M1	olfactory receptor, family 51, subfamily M, member 1
chr4_-_40211324	1.047		RBM47	RNA binding motif protein 47
chr11_-_123182266	1.026	NM_001005325	OR6M1	olfactory receptor, family 6, subfamily M, member 1
chr5_-_135729062	1.026	NM_001167576 NM_001167577 NM_020389	TRPC7	transient receptor potential cation channel, subfamily C, member 7
chr3_+_99592199	1.025	NM_001005516	OR5K3	olfactory receptor, family 5, subfamily K, member 3
chr11_+_6762823	1.011	NM_001004489	OR2AG1	olfactory receptor, family 2, subfamily AG, member 1
chr5_-_22889487	1.009	NM_004061	CDH12	cadherin 12, type 2 (N-cadherin 2)
chr1_+_246718487	0.983	NM_001004697	OR2T5	olfactory receptor, family 2, subfamily T, member 5
chrX_+_30171768	0.981	NM_002363 NM_177415	MAGEB1	melanoma antigen family B, 1
chr10_-_7722747	0.981		ITIH5	inter-alpha (globulin) inhibitor H5
chrX_+_18618965	0.980	NM_006240 NM_152224 NM_152226	PPEF1	protein phosphatase, EF-hand calcium binding domain 1
chr16_-_20323533	0.977	NM_174924	PDILT	protein disulfide isomerase-like, testis expressed
chr16_+_56567839	0.947	NM_199046 NM_199456	TEPP	testis, prostate and placenta expressed
chr3_-_152517204	0.944	NM_023915	GPR87	G protein-coupled receptor 87
chr14_+_22581215	0.942	NM_001099780	PSMB11	proteasome (prosome, macropain) subunit, beta type, 11
chr1_+_69998445	0.940	NM_020794	LRRC7	leucine rich repeat containing 7
chr6_+_30212488	0.925	NM_138700	TRIM40	tripartite motif containing 40
chr2_-_208763017	0.908	NM_001099334	C2orf80	chromosome 2 open reading frame 80
chr11_-_6870306	0.904	NM_003700	OR2D2	olfactory receptor, family 2, subfamily D, member 2
chr11_-_62508946	0.902	NM_004790 NM_153276 NM_153277 NM_153278	SLC22A6	solute carrier family 22 (organic anion transporter), member 6
chr19_-_15779935	0.898	NM_013940	OR10H1	olfactory receptor, family 10, subfamily H, member 1
chr22_+_38627129	0.897		GRAP2	GRB2-related adaptor protein 2
chr12_+_54316910	0.897	NM_206899	OR10P1	olfactory receptor, family 10, subfamily P, member 1
chr10_-_69095362	0.893	NM_001127384	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr11_-_56015421	0.879	NM_001005282	OR5M8	olfactory receptor, family 5, subfamily M, member 8
chr6_+_32713160	0.869	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr1_+_86707113	0.865	NM_001285	CLCA1	chloride channel accessory 1
chr11_+_123625632	0.865	NM_001002905	OR8G1	olfactory receptor, family 8, subfamily G, member 1
chr1_-_47468029	0.862	NM_003189	TAL1	T-cell acute lymphocytic leukemia 1
chr5_-_176258920	0.832	NM_002115	HK3	hexokinase 3 (white cell)
chr19_-_56026559	0.823	NM_017509 NM_138563 NM_138564	KLK15	kallikrein-related peptidase 15
chr1_-_180822686	0.811	NM_021133	RNASEL	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr3_-_46224791	0.794	NM_001295	CCR1	chemokine (C-C motif) receptor 1
chr12_+_21417068	0.786	NM_000415	IAPP	islet amyloid polypeptide
chr6_+_49575629	0.783	NM_001010904	GLYATL3	glycine-N-acyltransferase-like 3
chr11_+_55096179	0.780	NM_001004701	OR4C16	olfactory receptor, family 4, subfamily C, member 16
chr3_-_18455207	0.778	NM_001131010	SATB1	SATB homeobox 1
chr18_-_13905534	0.773	NM_000529	MC2R	melanocortin 2 receptor (adrenocorticotropic hormone)
chr15_+_56217686	0.765	NM_020980	AQP9	aquaporin 9
chr11_+_55884266	0.760	NM_001005205	OR8J1	olfactory receptor, family 8, subfamily J, member 1
chr11_-_5037432	0.755	NM_001005164	OR52E2	olfactory receptor, family 52, subfamily E, member 2
chr1_+_157526127	0.755	NM_002001	FCER1A	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr14_-_91111135	0.752	NM_001080113	C14orf184	chromosome 14 open reading frame 184
chr1_-_154484341	0.750	NM_198406 NM_024897	PAQR6	progestin and adipoQ receptor family member VI
chr11_-_47356562	0.739		SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr12_+_91620749	0.738	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr6_+_97117144	0.738	NM_001170807 NM_020482	FHL5	four and a half LIM domains 5
chr11_+_94398069	0.736	NM_001161630	KDM4DL	lysine (K)-specific demethylase 4D-like
chr17_-_23151601	0.735	NM_000625	NOS2	nitric oxide synthase 2, inducible
chr18_-_22699650	0.722	NM_001650	AQP4	aquaporin 4
chr1_-_240679380	0.715	NM_001195811 NM_001195812	PLD5	phospholipase D family, member 5
chr6_-_123999640	0.713	NM_006073	TRDN	triadin
chr6_+_14032655	0.713	NM_001165034	RNF182	ring finger protein 182
chr22_+_49333327	0.712	NM_138433	KLHDC7B	kelch domain containing 7B
chr16_+_28850760	0.710	NM_001178098 NM_001770	CD19	CD19 molecule
chr11_-_123918759	0.709	NM_001005195	OR8B12	olfactory receptor, family 8, subfamily B, member 12
chr2_-_113310796	0.709	NM_000576	IL1B	interleukin 1, beta
chr1_-_28392966	0.706	NM_001164722 NM_001164721	PTAFR	platelet-activating factor receptor
chr7_+_106293112	0.706	NM_002649	PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_+_120375053	0.704	NM_006952	UPK1B	uroplakin 1B
chr1_-_150328153	0.703	NM_001008536	TCHHL1	trichohyalin-like 1
chr5_+_79651545	0.702	NM_032567	SPZ1	spermatogenic leucine zipper 1
chr8_+_128497038	0.702	NM_001159542	POU5F1B	POU class 5 homeobox 1B
chr18_+_41560915	0.694	NM_001146037	SLC14A1	solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr5_+_57823017	0.693	NM_152687	GAPT	GRB2-binding adaptor protein, transmembrane
chr22_-_48865907	0.686	NM_139202	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr10_+_118370441	0.684	NM_005396	PNLIPRP2	pancreatic lipase-related protein 2
chr14_-_20340830	0.683	NM_002933 NM_198234 NM_198235	RNASE1	ribonuclease, RNase A family, 1 (pancreatic)
chr3_+_129124591	0.683	NM_207335	KBTBD12	kelch repeat and BTB (POZ) domain containing 12
chr10_-_72032519	0.683	NM_001083116 NM_005041	PRF1	perforin 1 (pore forming protein)
chr11_+_54891935	0.680	NM_001005275	OR4A15	olfactory receptor, family 4, subfamily A, member 15
chr22_-_48865864	0.680		MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr7_-_115458010	0.679	NM_001018058 NM_012252	TFEC	transcription factor EC
chr12_-_46883341	0.677	NM_001004134	OR10AD1	olfactory receptor, family 10, subfamily AD, member 1
chrX_+_134803450	0.675	NM_018666	SAGE1	sarcoma antigen 1
chr2_+_68445936	0.673		PLEK	pleckstrin
chr4_-_47678187	0.673	NM_001142564	CNGA1	cyclic nucleotide gated channel alpha 1
chr12_+_111829191	0.671		OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa
chr11_-_55518675	0.669	NM_003697	OR5F1	olfactory receptor, family 5, subfamily F, member 1
chr6_+_106653429	0.668	NM_182907	PRDM1	PR domain containing 1, with ZNF domain
chr14_+_69993969	0.664	NM_003813	ADAM21	ADAM metallopeptidase domain 21
chr21_+_24722913	0.664		FLJ42200	FLJ42200 protein
chr10_-_72032447	0.662		PRF1	perforin 1 (pore forming protein)
chr4_-_100575313	0.659	NM_001166504 NM_000673	ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_+_123600553	0.657	NM_001007249	OR8G2	olfactory receptor, family 8, subfamily G, member 2
chr11_-_5099422	0.656	NM_001005222	OR52A4	olfactory receptor, family 52, subfamily A, member 4
chr6_-_33085329	0.652	NM_002119	HLA-DOA	major histocompatibility complex, class II, DO alpha
chr16_+_29734785	0.645		C16orf53	chromosome 16 open reading frame 53
chr1_+_86662356	0.641	NM_006536	CLCA2	chloride channel accessory 2
chr18_-_56190980	0.640	NM_005912	MC4R	melanocortin 4 receptor
chr11_+_55078358	0.634	NM_001001920	OR4C15	olfactory receptor, family 4, subfamily C, member 15
chr6_+_47732181	0.626	NM_153839	GPR111	G protein-coupled receptor 111
chr14_-_20340377	0.624	NM_198232	RNASE1	ribonuclease, RNase A family, 1 (pancreatic)
chrX_+_130505630	0.620	NM_001004486	OR13H1	olfactory receptor, family 13, subfamily H, member 1
chr11_+_22316242	0.619	NM_020346	SLC17A6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr1_-_27573882	0.619	NM_003665 NM_173452	FCN3	ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
chr17_+_36493927	0.614	NM_033061	KRTAP4-7	keratin associated protein 4-7
chrX_-_110400406	0.607	NM_014289	CAPN6	calpain 6
chr1_+_210275752	0.605		DTL	denticleless homolog (Drosophila)
chr5_-_22889192	0.605		CDH12	cadherin 12, type 2 (N-cadherin 2)
chr17_+_44643067	0.601		ABI3	ABI family, member 3
chr1_+_24518501	0.596	NM_001195010	GRHL3	grainyhead-like 3 (Drosophila)
chr14_-_19252330	0.593	NM_001197287	OR11H2	olfactory receptor, family 11, subfamily H, member 2
chr16_+_49288550	0.592	NM_022162	NOD2	nucleotide-binding oligomerization domain containing 2
chr17_+_44642587	0.587	NM_001135186 NM_016428	ABI3	ABI family, member 3
chrX_+_12834659	0.586	NM_138636	TLR8	toll-like receptor 8
chr3_+_185253528	0.583	NM_130770	HTR3C	5-hydroxytryptamine (serotonin) receptor 3, family member C
chr19_-_46048033	0.582	NM_000762	CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6
chr19_-_56164628	0.582	NM_002774	KLK6	kallikrein-related peptidase 6
chr5_+_132021763	0.581	NM_002188	IL13	interleukin 13
chr6_+_29534109	0.581	NM_030883	OR2H1	olfactory receptor, family 2, subfamily H, member 1
chr19_-_60941551	0.576	NM_176820	NLRP9	NLR family, pyrin domain containing 9
chr1_-_159306037	0.574		ARHGAP30	Rho GTPase activating protein 30
chr6_+_116889248	0.570	NM_001010919	FAM26F	family with sequence similarity 26, member F
chr16_-_1761504	0.569		NME3	non-metastatic cells 3, protein expressed in
chr2_+_234266250	0.568	NM_001072	UGT1A6	UDP glucuronosyltransferase 1 family, polypeptide A6
chr1_+_47674275	0.565	NM_004474	FOXD2	forkhead box D2
chrX_+_27674846	0.563	NM_001136533	DCAF8L2	DDB1 and CUL4 associated factor 8-like 2
chr2_-_49235059	0.561	NM_000145 NM_181446	FSHR	follicle stimulating hormone receptor
chr19_+_10820105	0.559	NM_001136482	C19orf38	chromosome 19 open reading frame 38
chr7_+_143457083	0.558	NM_001001659	OR2A14	olfactory receptor, family 2, subfamily A, member 14
chr11_+_4965996	0.558	NM_021801	MMP26	matrix metallopeptidase 26
chr17_-_53764867	0.556
chr11_+_123315459	0.553	NM_001001965	OR4D5	olfactory receptor, family 4, subfamily D, member 5
chr11_+_62231741	0.552		GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr17_+_22996461	0.550		LGALS9	lectin, galactoside-binding, soluble, 9
chrX_-_100015783	0.548	NM_007052 NM_013955	NOX1	NADPH oxidase 1
chr5_-_112798436	0.547	NM_032028	TSSK1B	testis-specific serine kinase 1B
chr3_+_63613383	0.547	NM_001080537	SNTN	sentan, cilia apical structure protein
chr1_+_210275541	0.546	NM_016448	DTL	denticleless homolog (Drosophila)
chr5_-_180560535	0.545	NM_203297	TRIM7	tripartite motif containing 7
chr3_+_188568861	0.542	NM_022147	RTP4	receptor (chemosensory) transporter protein 4
chr2_+_68726457	0.541	NM_138964	PROKR1	prokineticin receptor 1
chr19_-_44518465	0.541		GMFG	glia maturation factor, gamma
chr4_+_157044296	0.540	NM_005651	TDO2	tryptophan 2,3-dioxygenase
chr11_-_6746763	0.538	NM_001004490	OR2AG2	olfactory receptor, family 2, subfamily AG, member 2
chr2_+_96355661	0.537	NM_178495 NM_001163524	ITPRIPL1	inositol 1,4,5-triphosphate receptor interacting protein-like 1
chr7_+_106897737	0.537	NM_005295	GPR22	G protein-coupled receptor 22
chr11_+_20577521	0.536	NM_004211	SLC6A5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr1_+_246617532	0.535	NM_001005471	OR2T6	olfactory receptor, family 2, subfamily T, member 6
chr21_-_31123797	0.534	NM_181606	KRTAP7-1	keratin associated protein 7-1 (gene/pseudogene)
chr22_-_29197944	0.533	NM_174975	SEC14L3	SEC14-like 3 (S. cerevisiae)
chr7_-_25234582	0.532	NM_022150	NPVF	neuropeptide VF precursor
chr17_-_29507663	0.529	NM_001094	ACCN1	amiloride-sensitive cation channel 1, neuronal
chrX_+_30158473	0.524	NM_002365	MAGEB3	melanoma antigen family B, 3
chrX_-_27909486	0.520	NM_001017930	DCAF8L1	DDB1 and CUL4 associated factor 8-like 1
chr7_+_141054621	0.520	NM_001105558	WEE2	WEE1 homolog 2 (S. pombe)
chr4_+_39874921	0.518	NM_004310	RHOH	ras homolog gene family, member H
chr7_-_115458064	0.513		TFEC	transcription factor EC
chr10_-_108448990	0.512		SORCS1	sortilin-related VPS10 domain containing receptor 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
4.82	3.94e-53	GO:0007608	sensory perception of smell
4.54	1.59e-52	GO:0007606	sensory perception of chemical stimulus
3.22	5.20e-42	GO:0007600	sensory perception
2.34	6.43e-29	GO:0050877	neurological system process
2.13	2.69e-27	GO:0003008	system process
1.35	5.37e-15	GO:0050896	response to stimulus
1.38	2.57e-13	GO:0032501	multicellular organismal process
2.07	3.10e-09	GO:0006955	immune response
1.69	1.78e-06	GO:0002376	immune system process
1.87	2.73e-06	GO:0006952	defense response
2.23	4.46e-05	GO:0045087	innate immune response
3.21	1.82e-02	GO:0034341	response to interferon-gamma

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.62	1.97e-28	GO:0071944	cell periphery
1.62	5.69e-28	GO:0005886	plasma membrane
1.45	2.75e-22	GO:0031224	intrinsic to membrane
1.45	1.34e-21	GO:0016021	integral to membrane
1.35	4.77e-17	GO:0044425	membrane part
1.24	2.31e-11	GO:0016020	membrane
1.55	7.08e-09	GO:0005576	extracellular region
2.44	4.82e-04	GO:0045111	intermediate filament cytoskeleton
2.57	5.01e-04	GO:0005882	intermediate filament
1.63	1.23e-03	GO:0005615	extracellular space
2.59	3.16e-03	GO:0009897	external side of plasma membrane
1.47	3.61e-03	GO:0005887	integral to plasma membrane
1.45	5.36e-03	GO:0031226	intrinsic to plasma membrane
1.49	7.52e-03	GO:0044421	extracellular region part
1.29	2.85e-02	GO:0044459	plasma membrane part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
4.98	9.05e-55	GO:0004984	olfactory receptor activity
3.21	3.46e-44	GO:0004930	G-protein coupled receptor activity
2.68	4.68e-43	GO:0004888	transmembrane receptor activity
2.32	1.69e-38	GO:0004872	receptor activity
2.08	2.65e-33	GO:0004871	signal transducer activity
2.08	2.65e-33	GO:0060089	molecular transducer activity
2.30	4.19e-03	GO:0005125	cytokine activity
4.04	5.50e-03	GO:0008009	chemokine activity
3.64	1.86e-02	GO:0042379	chemokine receptor binding