Motif ID: POU1F1.p2

Z-value: 1.596


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU1F1chr3_-_874083010.058.6e-01Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_14740694 3.337 NM_004963
 GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr13_-_45654292 1.516 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr21_-_14840506 1.424 NM_022136
 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr13_-_45654296 1.399 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_32742265 1.231 NM_002123
 HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr6_-_33149244 1.228 NM_033554
 HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr13_-_45654327 1.179 NM_002298
 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_-_131089552 1.154 NM_194277
 FRMD7
FERM domain containing 7
chr11_-_74478405 1.012 NM_001005285
 OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr6_+_167456230 1.003 NM_031409
 CCR6
chemokine (C-C motif) receptor 6
chr9_-_70780574 0.972


chr2_+_143351536 0.948 NM_001032998
NM_003937
 KYNU

kynureninase

chr12_+_111829191 0.936 OAS1
2',5'-oligoadenylate synthetase 1, 40/46kDa
chr4_-_47831002 0.923 NM_003328
 TXK
TXK tyrosine kinase
chr6_+_132000134 0.912 NM_005021
 ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr6_+_32515596 0.900 NM_019111
 HLA-DRA
major histocompatibility complex, class II, DR alpha
chr12_-_54150188 0.875 NM_001005499
 OR6C70
olfactory receptor, family 6, subfamily C, member 70
chr11_+_55319607 0.863 NM_001004735
 OR5D14
olfactory receptor, family 5, subfamily D, member 14
chr7_-_44985084 0.834 MYO1G
myosin IG
chr4_-_77547481 0.833 NM_001042784
 CCDC158
coiled-coil domain containing 158

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
10.42 4.90e-04 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
4.83 8.38e-03 GO:0019882 antigen processing and presentation
4.64 5.44e-03 GO:0060333 interferon-gamma-mediated signaling pathway
4.42 3.39e-26 GO:0007608 sensory perception of smell
4.23 1.60e-02 GO:0071346 cellular response to interferon-gamma
4.21 1.82e-26 GO:0007606 sensory perception of chemical stimulus
3.88 2.13e-02 GO:0034341 response to interferon-gamma
3.59 7.71e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.57 2.93e-02 GO:0050851 antigen receptor-mediated signaling pathway
3.51 1.95e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
3.33 3.73e-03 GO:0006805 xenobiotic metabolic process
3.33 3.73e-03 GO:0071466 cellular response to xenobiotic stimulus
3.31 4.20e-03 GO:0009410 response to xenobiotic stimulus
2.86 2.74e-18 GO:0007600 sensory perception
2.52 9.18e-06 GO:0050776 regulation of immune response
2.50 2.42e-04 GO:0045087 innate immune response
2.45 9.65e-03 GO:0050778 positive regulation of immune response
2.28 1.00e-07 GO:0006955 immune response
2.06 1.57e-05 GO:0006952 defense response
2.02 5.19e-10 GO:0050877 neurological system process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
12.65 1.06e-05 GO:0042613 MHC class II protein complex
6.92 2.35e-04 GO:0042611 MHC protein complex
1.54 2.83e-13 GO:0071944 cell periphery
1.53 1.08e-12 GO:0005886 plasma membrane
1.46 1.80e-03 GO:0005576 extracellular region
1.38 8.35e-10 GO:0031224 intrinsic to membrane
1.37 4.54e-09 GO:0016021 integral to membrane
1.30 1.22e-07 GO:0044425 membrane part
1.22 2.29e-05 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.98 2.38e-02 GO:0003823 antigen binding
4.57 1.71e-27 GO:0004984 olfactory receptor activity
2.87 6.58e-20 GO:0004930 G-protein coupled receptor activity
2.49 5.16e-21 GO:0004888 transmembrane receptor activity
2.11 7.46e-17 GO:0004872 receptor activity
1.86 3.34e-13 GO:0004871 signal transducer activity
1.86 3.34e-13 GO:0060089 molecular transducer activity