Motif ID: POU2F1..3.p2

Z-value: 1.922


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F1chr1_+_1654565720.611.2e-02Click!
POU2F2chr19_-_473283990.505.0e-02Click!
POU2F3chr11_+_1196161120.302.6e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_23754772 6.703 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr16_+_23754822 5.439 PRKCB
protein kinase C, beta
chr16_+_23754860 5.290 PRKCB
protein kinase C, beta
chr14_-_106084519 5.066 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_+_23754997 4.439 PRKCB
protein kinase C, beta
chr6_+_26291936 4.146 NM_003523
HIST1H2BE
histone cluster 1, H2be
chr1_+_226712430 3.561 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr1_-_153098811 3.021 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_+_50318801 2.963 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr3_+_99733432 2.885 NM_005290
GPR15
G protein-coupled receptor 15
chr6_-_33016561 2.811 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_27968906 2.728 NM_003514
HIST1H2AM
histone cluster 1, H2am
chr22_+_21065134 2.638 LOC100290481
immunoglobulin lambda light chain-like
chr6_-_26151863 2.313 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr17_-_16816113 2.288 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr1_+_205736095 2.264 NM_000573
NM_000651
CR1

complement component (3b/4b) receptor 1 (Knops blood group)

chr10_+_124897627 1.957 NM_005519
HMX2
H6 family homeobox 2
chr6_-_26232109 1.913 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr22_+_20316968 1.910 NM_152612
CCDC116
coiled-coil domain containing 116
chr15_+_81906983 1.818 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr6_+_26266311 1.791 NM_021063
NM_138720
HIST1H2BD

histone cluster 1, H2bd

chr17_-_59363352 1.755 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr12_+_56290229 1.737 NM_001111270
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr8_+_19840861 1.685 NM_000237
LPL
lipoprotein lipase
chr6_+_27222839 1.621 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr5_-_66528330 1.582 NM_005582
CD180
CD180 molecule
chr6_+_27969181 1.564 NM_003527
HIST1H2BO
histone cluster 1, H2bo
chr12_+_91620749 1.498 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr5_-_131907071 1.465 NM_000879
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr9_-_126573349 1.436 NM_001489
NM_033334
NR6A1

nuclear receptor subfamily 6, group A, member 1

chr3_+_114733907 1.436 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr22_+_21370394 1.397 IGL@
immunoglobulin lambda locus
chr12_-_10953427 1.381 NM_023920
TAS2R13
taste receptor, type 2, member 13
chr22_+_21042091 1.370 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr6_+_10693964 1.332 NM_145655
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr5_-_88155360 1.325 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr22_+_21094094 1.300


chr8_+_56954899 1.292 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr6_+_26232351 1.290 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr19_+_14554895 1.263 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr15_+_81907176 1.258 SH3GL3
SH3-domain GRB2-like 3
chr6_-_26324850 1.249 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr16_-_87280380 1.248 NM_178310
SNAI3
snail homolog 3 (Drosophila)
chr19_-_18253413 1.234 NM_005354
JUND
jun D proto-oncogene
chr6_+_32515596 1.218 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr8_+_56954946 1.215 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr10_-_64246129 1.214 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr21_-_31123797 1.211 NM_181606
KRTAP7-1
keratin associated protein 7-1 (gene/pseudogene)
chr22_+_20880159 1.203 IGLV6-57
immunoglobulin lambda variable 6-57
chr13_-_45640679 1.189 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_27222556 1.182 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr1_-_148124738 1.179 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr10_-_64246080 1.167 EGR2
early growth response 2
chr6_+_27323458 1.158 NM_005865
PRSS16
protease, serine, 16 (thymus)
chr9_-_139316523 1.139 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr8_+_19841010 1.127 LPL
lipoprotein lipase
chr22_+_20715340 1.125


chr6_-_27208507 1.123 NM_021058
HIST1H2BJ
histone cluster 1, H2bj
chr6_+_27208763 1.122 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr12_+_111829121 1.118 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr6_+_25834983 1.074 NM_170610
HIST1H2BA
histone cluster 1, H2ba
chr6_-_27890496 1.068 NM_021066
HIST1H2AJ
histone cluster 1, H2aj
chr6_-_168219380 1.065 NM_001122841
FRMD1
FERM domain containing 1
chr1_+_202000906 1.064 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr1_+_148089251 1.059 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr19_+_3523958 1.056 HMG20B
high-mobility group 20B
chr17_+_19999784 1.050 NM_001033554
NM_001033555
SPECC1

sperm antigen with calponin homology and coiled-coil domains 1

chr17_-_44249379 1.049 NM_001130918
TTLL6
tubulin tyrosine ligase-like family, member 6
chr19_-_18253048 1.041 JUND
jun D proto-oncogene
chr6_+_135558572 1.038


chr15_+_76171981 1.032 NM_001101404
SH2D7
SH2 domain containing 7
chr10_-_98021144 1.031 NM_001114094
NM_013314
BLNK

B-cell linker

chr6_+_27941012 1.031 NM_003511
HIST1H2AI
HIST1H2AL
histone cluster 1, H2ai
histone cluster 1, H2al
chr19_+_60803412 1.031 NM_153219
ZNF524
zinc finger protein 524
chr14_-_105763152 1.028 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr22_+_21495273 1.020


chr1_+_5975286 1.018 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr22_-_22426551 1.013 NM_013378
VPREB3
pre-B lymphocyte 3
chr1_+_5975345 1.009 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr7_+_142629251 1.002 NM_176882
TAS2R40
taste receptor, type 2, member 40
chr19_-_51856129 0.982 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr6_+_37245860 0.978 NM_002648
PIM1
pim-1 oncogene
chr19_-_18369407 0.976 NM_145256
LRRC25
leucine rich repeat containing 25
chr5_-_176868483 0.953 DOK3
docking protein 3
chr6_+_26359805 0.950 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr6_+_27883877 0.943 NM_003509
HIST1H2AI
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H3f
chr2_-_2313894 0.935 NM_015025
MYT1L
myelin transcription factor 1-like
chr6_+_34312979 0.932 HMGA1
high mobility group AT-hook 1
chr22_+_20880112 0.931


chr22_+_44059491 0.927 NM_001167574
NM_006953
UPK3A

uroplakin 3A

chr2_+_96790298 0.927 NM_020184
CNNM4
cyclin M4
chr11_-_31789431 0.926 NM_000280
NM_001604
PAX6

paired box 6

chr22_+_31080871 0.925 NM_006604
RFPL3
ret finger protein-like 3
chr15_-_38953628 0.923 NM_133639
RHOV
ras homolog gene family, member V
chr14_-_106184988 0.920 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_80344096 0.903 NM_030763
HMGN5
high-mobility group nucleosome binding domain 5
chr1_-_148126089 0.898 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr7_+_16759845 0.880 NM_014399
TSPAN13
tetraspanin 13
chrX_+_12903145 0.878 NM_021109
NM_183049
TMSB4X
TMSL3
thymosin beta 4, X-linked
thymosin-like 3
chr6_-_168222645 0.872 NM_024919
FRMD1
FERM domain containing 1
chr21_-_38415273 0.855 NM_005867
DSCR4
Down syndrome critical region gene 4
chr22_+_21407066 0.850


chr6_+_34312906 0.847 HMGA1
high mobility group AT-hook 1
chr19_+_17377502 0.842 LOC100507535
hypothetical LOC100507535
chr4_-_40212670 0.840 NM_019027
RBM47
RNA binding motif protein 47
chr2_-_157890400 0.840 NM_020711
ERMN
ermin, ERM-like protein
chr7_+_100021862 0.831 NM_033506
FBXO24
F-box protein 24
chr11_+_27019084 0.828 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_-_87280289 0.827 SNAI3
snail homolog 3 (Drosophila)
chr3_+_153074118 0.823 NM_033050
SUCNR1
succinate receptor 1
chr2_-_219614481 0.817 NM_152389
NM_194302
CCDC108

coiled-coil domain containing 108

chr17_+_60563963 0.811 RGS9
regulator of G-protein signaling 9
chr6_+_26381122 0.804 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr14_-_105862080 0.802 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr3_+_188130967 0.795 NM_173216
NM_173217
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chr6_+_97117144 0.795 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chr8_+_56954953 0.782 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr11_-_558419 0.770


chr19_-_18253259 0.762


chr19_+_59820413 0.758 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr8_+_19841209 0.755 LPL
lipoprotein lipase
chr19_+_3523950 0.754 HMG20B
high-mobility group 20B
chr6_+_34312667 0.752 HMGA1
high mobility group AT-hook 1
chr6_-_26141774 0.742 NM_003513
HIST1H2AB
histone cluster 1, H2ab
chr6_-_89984214 0.741 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr4_-_71751070 0.729 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr12_+_111829191 0.704 OAS1
2',5'-oligoadenylate synthetase 1, 40/46kDa
chrX_+_37524250 0.704 CYBB
cytochrome b-245, beta polypeptide
chr19_-_19142053 0.703 MEF2B
myocyte enhancer factor 2B
chr8_+_19841120 0.699 LPL
lipoprotein lipase
chr17_-_44047299 0.695 NM_024016
HOXB8
homeobox B8
chr15_-_38387357 0.692 PLCB2
phospholipase C, beta 2
chr7_-_100021658 0.690 LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr7_-_27206249 0.684 NM_000522
HOXA13
homeobox A13
chr2_-_238813365 0.683 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr12_-_8656705 0.675 NM_020661
AICDA
activation-induced cytidine deaminase
chr1_+_154386358 0.670 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_+_129124591 0.670 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr9_+_94766379 0.669 FGD3
FYVE, RhoGEF and PH domain containing 3
chr15_-_81037554 0.669 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr14_-_106241445 0.669 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr16_+_28850760 0.668 NM_001178098
NM_001770
CD19

CD19 molecule

chr13_-_69580459 0.662 NM_020866
KLHL1
kelch-like 1 (Drosophila)
chr6_+_34313007 0.662 HMGA1
high mobility group AT-hook 1
chr3_-_193928038 0.653 NM_004113
FGF12
fibroblast growth factor 12
chr6_-_31668476 0.647 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3


chr12_-_68291208 0.643 NM_201550
LRRC10
leucine rich repeat containing 10
chr6_+_34312641 0.641 HMGA1
high mobility group AT-hook 1
chr11_-_113935789 0.640 NM_152315
FAM55A
family with sequence similarity 55, member A
chr15_-_38387410 0.636 NM_004573
PLCB2
phospholipase C, beta 2
chrX_+_37524190 0.629 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr2_-_238813284 0.629 HES6
hairy and enhancer of split 6 (Drosophila)
chr11_+_527521 0.623 NM_198075
LRRC56
leucine rich repeat containing 56
chr17_-_34635446 0.615 NM_198993
STAC2
SH3 and cysteine rich domain 2
chr1_+_165564904 0.612 NM_001198783
POU2F1
POU class 2 homeobox 1
chrX_-_84521398 0.610 NM_024921
POF1B
premature ovarian failure, 1B
chr18_-_22696532 0.609 NM_004028
AQP4
aquaporin 4
chr18_+_74841262 0.608 NM_171999
SALL3
sal-like 3 (Drosophila)
chr7_+_37746520 0.593 NM_181791
GPR141
G protein-coupled receptor 141
chr1_-_203579932 0.592 KLHDC8A
kelch domain containing 8A
chr17_-_33179118 0.591 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr1_+_204797079 0.589 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr6_+_12825022 0.574 PHACTR1
phosphatase and actin regulator 1
chr6_-_99904251 0.573 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr1_+_148125090 0.573 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr17_-_53849888 0.569 RNF43
ring finger protein 43
chr13_-_52320774 0.564 NM_002590
NM_032949
PCDH8

protocadherin 8

chr17_-_4792542 0.560 NM_005022
PFN1
profilin 1
chr17_-_36850978 0.559 NM_006771
KRT38
keratin 38
chr8_-_72437020 0.556 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr17_+_60563917 0.555 NM_001081955
NM_001165933
NM_003835
RGS9


regulator of G-protein signaling 9


chr3_+_120799411 0.549 NM_015900
PLA1A
phospholipase A1 member A
chrX_+_153767803 0.548 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr7_-_44088608 0.540 POLM
polymerase (DNA directed), mu
chr5_+_2805261 0.536 NM_178569
C5orf38
chromosome 5 open reading frame 38
chr6_+_34312625 0.534 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr1_+_204797120 0.528 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr10_+_68355797 0.522 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr8_-_25371663 0.521 KCTD9
potassium channel tetramerisation domain containing 9
chr3_-_167037861 0.519 BCHE
butyrylcholinesterase
chr11_-_117552545 0.517 NM_004588
SCN2B
sodium channel, voltage-gated, type II, beta
chr12_+_120548831 0.513 NM_032790
ORAI1
ORAI calcium release-activated calcium modulator 1
chr1_-_194844061 0.512 NM_198503
KCNT2
potassium channel, subfamily T, member 2
chr19_-_17377383 0.503 NM_004335
BST2
bone marrow stromal cell antigen 2
chr22_+_21384862 0.503 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr14_+_22422270 0.502 NM_173527
REM2
RAS (RAD and GEM)-like GTP binding 2
chr22_-_14829803 0.502 NM_001005239
OR11H1
olfactory receptor, family 11, subfamily H, member 1
chr9_+_128716867 0.499 NM_001190729
NM_001190730
NM_014636
RALGPS1


Ral GEF with PH domain and SH3 binding motif 1


chr15_-_56145140 0.498 NM_003888
NM_170696
ALDH1A2

aldehyde dehydrogenase 1 family, member A2

chr3_+_63613383 0.497 NM_001080537
SNTN
sentan, cilia apical structure protein
chr14_-_105681377 0.494 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_63829616 0.488 NM_004451
ESRRA
estrogen-related receptor alpha
chr16_-_54466709 0.483 NM_001143685
NM_145024
CES5A

carboxylesterase 5A

chr2_-_51112743 0.481 NRXN1
neurexin 1
chr6_+_34312633 0.481 HMGA1
high mobility group AT-hook 1
chr22_+_21116283 0.477


chr6_+_34312554 0.476 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr18_-_59462469 0.475 NM_002974
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr3_-_167037946 0.473 NM_000055
BCHE
butyrylcholinesterase
chr2_-_104834344 0.466 LOC100506421
hypothetical LOC100506421

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
10.06 2.18e-16 GO:0006334 nucleosome assembly
9.44 2.76e-16 GO:0034728 nucleosome organization
9.55 9.35e-16 GO:0031497 chromatin assembly
8.60 3.76e-15 GO:0071824 protein-DNA complex subunit organization
7.62 7.28e-15 GO:0006333 chromatin assembly or disassembly
8.75 1.02e-14 GO:0065004 protein-DNA complex assembly
7.31 1.14e-12 GO:0006323 DNA packaging
6.52 6.36e-12 GO:0071103 DNA conformation change
2.99 4.25e-06 GO:0006325 chromatin organization
3.27 6.76e-06 GO:0034622 cellular macromolecular complex assembly
2.46 1.02e-05 GO:0006955 immune response
2.78 4.57e-05 GO:0034621 cellular macromolecular complex subunit organization
1.31 5.87e-04 GO:0050896 response to stimulus
1.92 6.47e-04 GO:0002376 immune system process
2.37 1.08e-03 GO:0051276 chromosome organization
2.09 4.00e-03 GO:0006952 defense response
2.92 7.66e-03 GO:0050778 positive regulation of immune response
2.15 8.00e-03 GO:0065003 macromolecular complex assembly
3.21 8.67e-03 GO:0002253 activation of immune response
4.28 2.67e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.94 3.72e-02 GO:0043933 macromolecular complex subunit organization
4.12 3.96e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
13.94 1.21e-19 GO:0000786 nucleosome
8.91 1.79e-14 GO:0032993 protein-DNA complex
5.10 1.51e-12 GO:0000785 chromatin
2.85 3.80e-06 GO:0044427 chromosomal part
2.46 9.36e-05 GO:0005694 chromosome
1.33 4.88e-03 GO:0071944 cell periphery
1.32 1.34e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
11.70 7.61e-09 GO:0003823 antigen binding
1.64 3.53e-03 GO:0004872 receptor activity
1.52 1.08e-02 GO:0004871 signal transducer activity
1.52 1.08e-02 GO:0060089 molecular transducer activity