Motif ID: POU2F1..3.p2

Z-value: 1.922


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F1chr1_+_1654565720.611.2e-02Click!
POU2F2chr19_-_473283990.505.0e-02Click!
POU2F3chr11_+_1196161120.302.6e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_23754772 6.703 NM_002738
NM_212535
 PRKCB

protein kinase C, beta

chr16_+_23754822 5.439 PRKCB
protein kinase C, beta
chr16_+_23754860 5.290 PRKCB
protein kinase C, beta
chr14_-_106084519 5.066 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_+_23754997 4.439 PRKCB
protein kinase C, beta
chr6_+_26291936 4.146 NM_003523
 HIST1H2BE
histone cluster 1, H2be
chr1_+_226712430 3.561 NM_175055
 HIST3H2BB
histone cluster 3, H2bb
chr1_-_153098811 3.021 NM_170782
 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_+_50318801 2.963 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr3_+_99733432 2.885 NM_005290
 GPR15
G protein-coupled receptor 15
chr6_-_33016561 2.811 NM_002118
 HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_27968906 2.728 NM_003514
 HIST1H2AM
histone cluster 1, H2am
chr22_+_21065134 2.638 LOC100290481
immunoglobulin lambda light chain-like
chr6_-_26151863 2.313 NM_021062
 HIST1H2BB
histone cluster 1, H2bb
chr17_-_16816113 2.288 NM_012452
 TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr1_+_205736095 2.264 NM_000573
NM_000651
 CR1

complement component (3b/4b) receptor 1 (Knops blood group)

chr10_+_124897627 1.957 NM_005519
 HMX2
H6 family homeobox 2
chr6_-_26232109 1.913 NM_003526
 HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr22_+_20316968 1.910 NM_152612
 CCDC116
coiled-coil domain containing 116
chr15_+_81906983 1.818 NM_003027
 SH3GL3
SH3-domain GRB2-like 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
10.06 2.18e-16 GO:0006334 nucleosome assembly
9.55 9.35e-16 GO:0031497 chromatin assembly
9.44 2.76e-16 GO:0034728 nucleosome organization
8.75 1.02e-14 GO:0065004 protein-DNA complex assembly
8.60 3.76e-15 GO:0071824 protein-DNA complex subunit organization
7.62 7.28e-15 GO:0006333 chromatin assembly or disassembly
7.31 1.14e-12 GO:0006323 DNA packaging
6.52 6.36e-12 GO:0071103 DNA conformation change
4.28 2.67e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
4.12 3.96e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.27 6.76e-06 GO:0034622 cellular macromolecular complex assembly
3.21 8.67e-03 GO:0002253 activation of immune response
2.99 4.25e-06 GO:0006325 chromatin organization
2.92 7.66e-03 GO:0050778 positive regulation of immune response
2.78 4.57e-05 GO:0034621 cellular macromolecular complex subunit organization
2.46 1.02e-05 GO:0006955 immune response
2.37 1.08e-03 GO:0051276 chromosome organization
2.15 8.00e-03 GO:0065003 macromolecular complex assembly
2.09 4.00e-03 GO:0006952 defense response
1.94 3.72e-02 GO:0043933 macromolecular complex subunit organization

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
13.94 1.21e-19 GO:0000786 nucleosome
8.91 1.79e-14 GO:0032993 protein-DNA complex
5.10 1.51e-12 GO:0000785 chromatin
2.85 3.80e-06 GO:0044427 chromosomal part
2.46 9.36e-05 GO:0005694 chromosome
1.33 4.88e-03 GO:0071944 cell periphery
1.32 1.34e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
11.70 7.61e-09 GO:0003823 antigen binding
1.64 3.53e-03 GO:0004872 receptor activity
1.52 1.08e-02 GO:0004871 signal transducer activity
1.52 1.08e-02 GO:0060089 molecular transducer activity