Motif ID: PAX2.p2

Z-value: 0.791


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
PAX2 5076 paired box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX2chr10_+_102495327-0.766.4e-04Click!


Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_85457469 1.520 PICALM
phosphatidylinositol binding clathrin assembly protein
chr5_+_133734768 1.474 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr6_+_160310118 1.316 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr20_+_46971618 1.288 NM_006420
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr11_+_7574992 1.284 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_-_85457753 1.281 NM_001008660
NM_007166
PICALM

phosphatidylinositol binding clathrin assembly protein

chr11_-_85457736 1.243 PICALM
phosphatidylinositol binding clathrin assembly protein
chr12_-_56432385 1.210 NM_000075
CDK4
cyclin-dependent kinase 4
chr2_+_46779553 1.195 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr14_+_23654161 1.149 DCAF11
DDB1 and CUL4 associated factor 11
chr15_-_63871492 1.143 DENND4A
DENN/MADD domain containing 4A
chr17_+_55051818 1.128 NM_004859
CLTC
clathrin, heavy chain (Hc)
chr15_-_63871598 1.079 NM_001144823
NM_005848
DENND4A

DENN/MADD domain containing 4A

chr2_+_46779827 1.077 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr18_+_9126742 1.066 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr3_+_19963534 1.051 NM_004162
RAB5A
RAB5A, member RAS oncogene family
chr17_+_55052060 1.029 CLTC
clathrin, heavy chain (Hc)
chr17_+_55052046 1.012 CLTC
clathrin, heavy chain (Hc)
chr6_+_87921980 1.003 NM_015021
ZNF292
zinc finger protein 292
chr14_+_23653848 0.984 DCAF11
DDB1 and CUL4 associated factor 11
chr6_+_127629677 0.959 NM_030963
RNF146
ring finger protein 146
chr9_+_6747919 0.954 KDM4C
lysine (K)-specific demethylase 4C
chr14_+_23654307 0.888 NM_181357
DCAF11
DDB1 and CUL4 associated factor 11
chr7_-_95789204 0.878 NM_001160210
NM_014251
SLC25A13

solute carrier family 25, member 13 (citrin)

chr7_+_140042932 0.875 NM_004546
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chrX_+_100549869 0.864 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr5_+_133735004 0.857 UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr11_-_18300246 0.849 NM_007216
NM_181507
NM_181508
HPS5


Hermansky-Pudlak syndrome 5


chrX_+_100549885 0.848 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr10_+_69314347 0.835 NM_012238
SIRT1
sirtuin 1
chr2_+_42249896 0.833 NM_001145076
NM_019063
EML4

echinoderm microtubule associated protein like 4

chr17_+_55052065 0.821 CLTC
clathrin, heavy chain (Hc)
chr9_-_126573349 0.814 NM_001489
NM_033334
NR6A1

nuclear receptor subfamily 6, group A, member 1

chr17_+_55052185 0.807


chr12_-_44670475 0.793 SCAF11
SR-related CTD-associated factor 11
chrX_+_100549839 0.782 NM_001032393
NM_019597
HNRNPH2

heterogeneous nuclear ribonucleoprotein H2 (H')

chrX_-_100549561 0.776 NM_000169
GLA
galactosidase, alpha
chr6_+_143423656 0.769 NM_016108
AIG1
androgen-induced 1
chrX_+_84385649 0.767 NM_021998
ZNF711
zinc finger protein 711
chr10_+_111959978 0.763 NM_001008541
MXI1
MAX interactor 1
chr2_+_228045053 0.757 AGFG1
ArfGAP with FG repeats 1
chr17_-_46692369 0.755 NM_017643
MBTD1
mbt domain containing 1
chr10_+_69990050 0.752 NM_030625
TET1
tet oncogene 1
chr2_+_135392857 0.744 NM_001241
NM_058241
CCNT2

cyclin T2

chr12_+_12656022 0.743 NM_001310
CREBL2
cAMP responsive element binding protein-like 2
chr2_+_177965734 0.742 AGPS
alkylglycerone phosphate synthase
chr14_+_100270222 0.740 DLK1
delta-like 1 homolog (Drosophila)
chr15_+_57696016 0.737 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr7_-_135263737 0.735 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chrX_+_100549861 0.733 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr1_-_113300351 0.730 NM_003051
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr8_-_126173203 0.729 KIAA0196
KIAA0196
chr16_-_5023934 0.726 NM_016256
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr12_-_122415327 0.723 SBNO1
strawberry notch homolog 1 (Drosophila)
chr17_+_25467948 0.717 NM_032141
CCDC55
coiled-coil domain containing 55
chr2_+_219751230 0.717 FAM134A
family with sequence similarity 134, member A
chr3_+_19963865 0.715 RAB5A
RAB5A, member RAS oncogene family
chr15_+_57696200 0.703 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_-_245237925 0.700 ZNF695
zinc finger protein 695
chrX_+_30581523 0.696 GK
glycerol kinase
chr21_-_39642880 0.689 NM_004965
HMGN1
high-mobility group nucleosome binding domain 1
chr8_-_126173189 0.689 KIAA0196
KIAA0196
chr12_+_12656109 0.685 CREBL2
cAMP responsive element binding protein-like 2
chr2_+_228045121 0.683 NM_001135187
NM_001135188
NM_001135189
NM_004504
AGFG1



ArfGAP with FG repeats 1



chr8_-_126173186 0.680 KIAA0196
KIAA0196
chr6_-_53321706 0.680 NM_021814
ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr10_-_45410197 0.678 NM_001002265
NM_145021
MARCH8

membrane-associated ring finger (C3HC4) 8

chr14_+_23653819 0.676 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr17_-_73636386 0.672 NM_001127198
TMC6
transmembrane channel-like 6
chr2_+_219751192 0.672 FAM134A
family with sequence similarity 134, member A
chr8_-_126173108 0.669 KIAA0196
KIAA0196
chr3_-_171382066 0.661 PHC3
polyhomeotic homolog 3 (Drosophila)
chr1_-_115060904 0.659 NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr6_-_53321545 0.657 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr14_+_22860511 0.649 PABPN1
poly(A) binding protein, nuclear 1
chr4_-_47160403 0.646 NM_017845
COMMD8
COMM domain containing 8
chr2_-_177965626 0.644 LOC100130691
hypothetical LOC100130691
chr2_-_240613480 0.643 NM_004544
NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr12_+_110935618 0.641 ERP29
endoplasmic reticulum protein 29
chr3_-_198509276 0.639 DLG1
discs, large homolog 1 (Drosophila)
chr11_-_107598472 0.638 NPAT
nuclear protein, ataxia-telangiectasia locus
chrX_+_84385693 0.638 ZNF711
zinc finger protein 711
chr6_+_143423723 0.637 AIG1
androgen-induced 1
chr14_+_23653745 0.635 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr6_-_109810396 0.634 NM_001142401
NM_001142402
NM_001142403
NM_001142404
NM_006016
CD164




CD164 molecule, sialomucin




chr18_+_30875297 0.631 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr20_+_57948803 0.630 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr6_+_105511615 0.625 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr12_-_122415708 0.620 SBNO1
strawberry notch homolog 1 (Drosophila)
chr14_-_64040072 0.620 NM_006977
ZBTB25
zinc finger and BTB domain containing 25
chr14_+_54807855 0.618 FBXO34
F-box protein 34
chr5_-_94916416 0.614 NM_014639
TTC37
tetratricopeptide repeat domain 37
chr5_-_167938875 0.613 PANK3
pantothenate kinase 3
chr2_+_62787534 0.609 NM_001142614
EHBP1
EH domain binding protein 1
chr2_+_177785667 0.608 NM_194247
HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr2_-_20115269 0.608 NM_014713
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr2_+_86801081 0.606 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr6_-_53321658 0.597 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr1_+_159550789 0.593 NM_001035511
NM_001035512
NM_001035513
NM_003001
SDHC



succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa



chr11_-_118757574 0.592 NM_004205
USP2
ubiquitin specific peptidase 2
chr1_-_77920914 0.592 NM_015534
ZZZ3
zinc finger, ZZ-type containing 3
chr13_+_48582389 0.590 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr4_-_113777569 0.589 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr4_-_186584031 0.589 NM_018359
UFSP2
UFM1-specific peptidase 2
chr11_-_82460518 0.588 RAB30
RAB30, member RAS oncogene family
chr5_-_167938991 0.586 NM_024594
PANK3
pantothenate kinase 3
chr10_+_76639917 0.586 NM_001184823
VDAC2
voltage-dependent anion channel 2
chr16_+_23754822 0.585 PRKCB
protein kinase C, beta
chr11_+_7491789 0.584 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_-_47160476 0.582 COMMD8
COMM domain containing 8
chr12_-_44670613 0.578 SCAF11
SR-related CTD-associated factor 11
chr6_-_84994032 0.573 NM_014895
KIAA1009
KIAA1009
chrX_-_7855400 0.568 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chr11_-_82460531 0.566 NM_014488
RAB30
RAB30, member RAS oncogene family
chr14_-_35348086 0.566 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr10_+_70553949 0.565 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr14_-_19993032 0.564 NM_017807
OSGEP
O-sialoglycoprotein endopeptidase
chr3_-_151963653 0.562 NM_005067
SIAH2
seven in absentia homolog 2 (Drosophila)
chr3_-_151963607 0.561 SIAH2
seven in absentia homolog 2 (Drosophila)
chr7_-_103635587 0.561 NM_181747
NM_002553
ORC5

origin recognition complex, subunit 5

chr12_-_75477692 0.558 NM_001003712
NM_020841
OSBPL8

oxysterol binding protein-like 8

chr20_+_37024383 0.557 NM_001190809
NM_021931
DHX35

DEAH (Asp-Glu-Ala-His) box polypeptide 35

chr8_-_54918389 0.553 NM_015941
NM_213619
ATP6V1H

ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

chr8_+_98725505 0.551 NM_178812
MTDH
metadherin
chr14_-_67353046 0.550 NM_015346
ZFYVE26
zinc finger, FYVE domain containing 26
chr11_+_120828275 0.549 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr9_+_130749812 0.549 NUP188
nucleoporin 188kDa
chr10_+_70553862 0.547 NM_001035260
NM_004896
VPS26A

vacuolar protein sorting 26 homolog A (S. pombe)

chr10_-_97311084 0.541 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr2_-_8895129 0.539 NM_020738
KIDINS220
kinase D-interacting substrate, 220kDa
chr1_-_113300138 0.537 NM_001166496
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr11_-_107598538 0.535 NM_002519
NPAT
nuclear protein, ataxia-telangiectasia locus
chr6_+_64340388 0.531 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr3_-_197293377 0.530 TFRC
transferrin receptor (p90, CD71)
chr10_+_70553936 0.529 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr3_-_198509808 0.529 NM_001098424
NM_004087
DLG1

discs, large homolog 1 (Drosophila)

chr8_-_126173055 0.527 KIAA0196
KIAA0196
chr9_-_14769530 0.527 NM_001177704
FREM1
FRAS1 related extracellular matrix 1
chr21_-_39642935 0.527 HMGN1
high-mobility group nucleosome binding domain 1
chr3_+_140545528 0.525 NM_020191
MRPS22
mitochondrial ribosomal protein S22
chr3_+_67131416 0.525 NM_032505
KBTBD8
kelch repeat and BTB (POZ) domain containing 8
chr6_-_109810310 0.524 CD164
CD164 molecule, sialomucin
chr2_+_105320440 0.524 NM_024093
C2orf49
chromosome 2 open reading frame 49
chr4_-_77354011 0.524 NM_005506
SCARB2
scavenger receptor class B, member 2
chr2_-_240613357 0.523 NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr1_-_209818675 0.522 NM_021194
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr10_+_76256305 0.518 NM_012330
MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr2_-_64734544 0.518 NM_014755
SERTAD2
SERTA domain containing 2
chr17_+_38247493 0.517 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr2_-_44076616 0.514 LRPPRC
leucine-rich PPR-motif containing
chr2_-_24869718 0.514 NM_001013663
C2orf79
chromosome 2 open reading frame 79
chr5_-_145542428 0.512 NM_020117
LARS
leucyl-tRNA synthetase
chr2_+_170259195 0.511 NM_144711
NM_001008489
PHOSPHO2-KLHL23
KLHL23
PHOSPHO2
PHOSPHO2-KLHL23 read-through transcript
kelch-like 23 (Drosophila)
phosphatase, orphan 2
chr3_-_171382213 0.509 NM_024947
PHC3
polyhomeotic homolog 3 (Drosophila)
chr11_-_118167073 0.509 DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr2_+_86800898 0.507 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr11_-_118757477 0.506 USP2
ubiquitin specific peptidase 2
chr5_+_65476418 0.505 NM_139168
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr1_-_33055431 0.505 YARS
tyrosyl-tRNA synthetase
chrX_+_55760774 0.504 NM_006064
NM_016656
RRAGB

Ras-related GTP binding B

chr1_-_115060857 0.501 NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr2_-_136311219 0.499 NM_002299
LCT
lactase
chr1_+_52294554 0.498 BTF3L4
basic transcription factor 3-like 4
chr11_-_36267550 0.498 NM_001101653
NM_014186
COMMD9

COMM domain containing 9

chr2_-_177836773 0.498 NM_001145412
NM_001145413
NFE2L2

nuclear factor (erythroid-derived 2)-like 2

chr17_+_50697355 0.497 HLF
hepatic leukemia factor
chr6_+_138230045 0.496 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr2_-_44076620 0.495 LRPPRC
leucine-rich PPR-motif containing
chr12_+_22669352 0.495 ETNK1
ethanolamine kinase 1
chr21_-_34909014 0.494 NM_004414
RCAN1
regulator of calcineurin 1
chr8_-_54918369 0.493 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr11_+_7491576 0.493 NM_003621
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_+_69314714 0.492 SIRT1
sirtuin 1
chr1_-_92724181 0.492 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr2_+_86800940 0.491 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr7_-_87343599 0.490 NM_018843
SLC25A40
solute carrier family 25, member 40
chr14_-_22468445 0.490 NM_001039619
NM_006109
PRMT5

protein arginine methyltransferase 5

chr2_-_176575171 0.487 NM_030650
KIAA1715
KIAA1715
chrX_+_146801236 0.487 FMR1
fragile X mental retardation 1
chr1_+_200191241 0.486 NM_006335
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr7_+_96473225 0.484 NM_005222
DLX6
distal-less homeobox 6
chr14_-_34661156 0.484 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr4_+_113777568 0.482 NM_016648
LARP7
La ribonucleoprotein domain family, member 7
chr5_-_137396677 0.482 NM_001101800
NM_001101801
NM_016603
FAM13B


family with sequence similarity 13, member B


chr17_+_44429748 0.482 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr14_-_54438913 0.482 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr2_-_21081694 0.481 APOB
apolipoprotein B (including Ag(x) antigen)
chr2_-_25328452 0.481 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chrX_-_76928142 0.480 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr6_-_122834580 0.479 NM_020755
SERINC1
serine incorporator 1
chr2_-_171725604 0.478 NM_012290
TLK1
tousled-like kinase 1
chr8_-_126173227 0.477 NM_014846
KIAA0196
KIAA0196
chr8_+_67787444 0.475 NM_001033578
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr6_+_155579788 0.474 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr18_+_30810889 0.473 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr7_-_105712565 0.473 NAMPT
nicotinamide phosphoribosyltransferase
chr6_-_112515329 0.473 NM_016262
TUBE1
tubulin, epsilon 1
chr10_-_3817205 0.472 KLF6
Kruppel-like factor 6
chrX_+_47305459 0.472 NM_001654
ARAF
v-raf murine sarcoma 3611 viral oncogene homolog
chr13_-_49597776 0.471 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 2.37e-15 GO:0044237 cellular metabolic process
1.29 1.08e-14 GO:0044260 cellular macromolecule metabolic process
1.19 3.07e-13 GO:0008152 metabolic process
1.25 6.18e-13 GO:0043170 macromolecule metabolic process
1.36 3.72e-12 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 8.69e-12 GO:0090304 nucleic acid metabolic process
1.20 1.14e-11 GO:0044238 primary metabolic process
1.45 1.49e-11 GO:0010467 gene expression
1.31 2.37e-10 GO:0034641 cellular nitrogen compound metabolic process
1.43 7.03e-10 GO:0016070 RNA metabolic process
1.29 1.91e-09 GO:0006807 nitrogen compound metabolic process
1.10 5.13e-09 GO:0009987 cellular process
1.62 2.15e-08 GO:0046907 intracellular transport
1.43 2.21e-06 GO:0051641 cellular localization
1.46 2.58e-06 GO:0051649 establishment of localization in cell
1.61 4.87e-06 GO:0006396 RNA processing
1.66 9.39e-06 GO:0016071 mRNA metabolic process
1.27 3.23e-05 GO:0044267 cellular protein metabolic process
1.33 5.80e-05 GO:0009059 macromolecule biosynthetic process
1.21 8.50e-05 GO:0071840 cellular component organization or biogenesis
1.72 8.58e-05 GO:0006397 mRNA processing
1.33 1.16e-04 GO:0034645 cellular macromolecule biosynthetic process
1.37 1.17e-04 GO:0033036 macromolecule localization
1.21 3.63e-04 GO:0016043 cellular component organization
1.78 4.38e-04 GO:0008380 RNA splicing
1.97 4.43e-04 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.97 4.43e-04 GO:0000398 nuclear mRNA splicing, via spliceosome
1.95 4.96e-04 GO:0000375 RNA splicing, via transesterification reactions
1.25 5.20e-04 GO:0044249 cellular biosynthetic process
1.40 7.06e-04 GO:0007049 cell cycle
1.24 9.10e-04 GO:0009058 biosynthetic process
1.30 1.07e-03 GO:0006996 organelle organization
1.20 3.97e-03 GO:0019538 protein metabolic process
2.04 4.94e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.21 5.15e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.63 6.22e-03 GO:0044419 interspecies interaction between organisms
1.63 6.27e-03 GO:0016568 chromatin modification
2.09 8.19e-03 GO:0006403 RNA localization
2.10 8.73e-03 GO:0050657 nucleic acid transport
2.10 8.73e-03 GO:0050658 RNA transport
2.10 8.73e-03 GO:0051236 establishment of RNA localization
1.18 9.43e-03 GO:0060255 regulation of macromolecule metabolic process
1.35 1.11e-02 GO:0008104 protein localization
1.51 1.20e-02 GO:0034613 cellular protein localization
1.48 1.32e-02 GO:0000278 mitotic cell cycle
1.65 1.62e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.50 1.64e-02 GO:0070727 cellular macromolecule localization
1.39 1.71e-02 GO:0033554 cellular response to stress
1.20 2.11e-02 GO:0071842 cellular component organization at cellular level
1.60 2.20e-02 GO:0030163 protein catabolic process
1.17 2.26e-02 GO:0031323 regulation of cellular metabolic process
1.37 2.44e-02 GO:0045184 establishment of protein localization
1.38 2.69e-02 GO:0022402 cell cycle process
1.62 2.78e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.16 2.86e-02 GO:0019222 regulation of metabolic process
1.37 2.92e-02 GO:0015031 protein transport
1.48 3.02e-02 GO:0044265 cellular macromolecule catabolic process
1.61 3.17e-02 GO:0044257 cellular protein catabolic process
1.62 3.55e-02 GO:0019941 modification-dependent protein catabolic process
1.44 4.17e-02 GO:0009057 macromolecule catabolic process
1.61 4.58e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.60 4.59e-02 GO:0070647 protein modification by small protein conjugation or removal

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 3.27e-42 GO:0044424 intracellular part
1.18 8.23e-41 GO:0005622 intracellular
1.23 2.45e-34 GO:0043231 intracellular membrane-bounded organelle
1.23 3.05e-34 GO:0043227 membrane-bounded organelle
1.20 1.58e-31 GO:0043229 intracellular organelle
1.20 3.38e-31 GO:0043226 organelle
1.21 1.88e-23 GO:0005737 cytoplasm
1.29 1.05e-22 GO:0005634 nucleus
1.26 4.72e-19 GO:0044422 organelle part
1.26 1.32e-18 GO:0044446 intracellular organelle part
1.22 3.87e-15 GO:0044444 cytoplasmic part
1.44 5.65e-15 GO:0044428 nuclear part
1.31 8.10e-14 GO:0032991 macromolecular complex
1.39 6.87e-13 GO:0043233 organelle lumen
1.39 1.30e-12 GO:0070013 intracellular organelle lumen
1.38 1.31e-12 GO:0031974 membrane-enclosed lumen
1.52 4.44e-12 GO:0005654 nucleoplasm
1.42 4.44e-11 GO:0031981 nuclear lumen
1.31 5.89e-11 GO:0043234 protein complex
1.34 4.09e-08 GO:0005829 cytosol
1.55 1.50e-06 GO:0044451 nucleoplasm part
2.36 4.79e-04 GO:0000776 kinetochore
1.04 5.17e-04 GO:0044464 cell part
1.04 5.42e-04 GO:0005623 cell
1.31 7.66e-04 GO:0005739 mitochondrion
1.21 8.50e-04 GO:0043228 non-membrane-bounded organelle
1.21 8.50e-04 GO:0043232 intracellular non-membrane-bounded organelle
2.01 2.33e-03 GO:0005681 spliceosomal complex
1.23 3.07e-03 GO:0031090 organelle membrane
1.49 7.32e-03 GO:0044427 chromosomal part
1.47 7.39e-03 GO:0030529 ribonucleoprotein complex
1.90 8.75e-03 GO:0005769 early endosome
1.49 9.50e-03 GO:0005768 endosome
1.43 1.34e-02 GO:0005694 chromosome
1.38 1.38e-02 GO:0031967 organelle envelope
3.68 1.90e-02 GO:0031519 PcG protein complex
1.35 3.43e-02 GO:0031975 envelope
1.82 3.85e-02 GO:0000775 chromosome, centromeric region
1.65 4.16e-02 GO:0016604 nuclear body

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 2.14e-20 GO:0005515 protein binding
1.10 6.11e-14 GO:0005488 binding
1.32 1.57e-08 GO:0000166 nucleotide binding
1.25 1.63e-07 GO:0003676 nucleic acid binding
1.31 4.71e-06 GO:0017076 purine nucleotide binding
1.50 4.78e-06 GO:0003723 RNA binding
1.31 1.02e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.30 1.57e-05 GO:0032553 ribonucleotide binding
1.30 1.57e-05 GO:0032555 purine ribonucleotide binding
1.32 5.59e-05 GO:0030554 adenyl nucleotide binding
1.69 7.59e-05 GO:0003712 transcription cofactor activity
1.68 8.74e-05 GO:0000988 protein binding transcription factor activity
1.68 8.74e-05 GO:0000989 transcription factor binding transcription factor activity
1.31 1.48e-04 GO:0032559 adenyl ribonucleotide binding
1.32 1.52e-04 GO:0005524 ATP binding
1.78 2.89e-03 GO:0003713 transcription coactivator activity
1.76 5.24e-03 GO:0004842 ubiquitin-protein ligase activity
1.13 5.38e-03 GO:0003824 catalytic activity
1.71 8.94e-03 GO:0019787 small conjugating protein ligase activity
1.49 1.64e-02 GO:0016874 ligase activity
1.60 2.33e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.20 2.48e-02 GO:0003677 DNA binding