Motif ID: SPZ1.p2

Z-value: 0.783


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_796515450.116.8e-01Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_13436802 1.332 NM_024923
NUP210
nucleoporin 210kDa
chr20_-_30636535 1.255 LOC284804
hypothetical protein LOC284804
chr9_+_70509925 1.166 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr6_-_119712596 1.088 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr18_-_26935883 0.943 NM_004949
NM_024422
DSC2

desmocollin 2

chr1_-_32574185 0.901 NM_023009
MARCKSL1
MARCKS-like 1
chr3_-_13436725 0.899 NUP210
nucleoporin 210kDa
chr8_+_142471290 0.893


chr2_+_119905812 0.826 NM_183240
TMEM37
transmembrane protein 37
chr7_-_103417198 0.804 NM_005045
NM_173054
RELN

reelin

chr12_-_52980914 0.791 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chrX_-_132947141 0.700 GPC3
glypican 3
chr12_-_52980984 0.669 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr12_-_24606616 0.669 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr6_+_37245860 0.612 NM_002648
PIM1
pim-1 oncogene
chr1_+_166172679 0.609 DCAF6
DDB1 and CUL4 associated factor 6
chrX_-_132947290 0.603 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chr1_-_159459999 0.554 NM_001643
APOA2
apolipoprotein A-II
chr2_-_174537354 0.532 SP3
Sp3 transcription factor
chr2_+_79593679 0.528 CTNNA2
catenin (cadherin-associated protein), alpha 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 61 entries
enrichment   p-value GO term description
1.58 7.37e-05 GO:0016568 chromatin modification
1.56 6.96e-03 GO:0010608 posttranscriptional regulation of gene expression
1.48 6.24e-04 GO:0006325 chromatin organization
1.45 4.64e-02 GO:0044419 interspecies interaction between organisms
1.41 5.69e-04 GO:0051276 chromosome organization
1.37 5.79e-05 GO:0006351 transcription, DNA-dependent
1.37 3.86e-02 GO:0016071 mRNA metabolic process
1.36 5.32e-03 GO:0010628 positive regulation of gene expression
1.35 2.50e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.34 5.18e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 9.92e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.33 1.13e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.33 3.63e-02 GO:0051254 positive regulation of RNA metabolic process
1.32 4.54e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.31 1.65e-03 GO:0032774 RNA biosynthetic process
1.31 1.86e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.31 1.16e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.31 1.35e-02 GO:0009891 positive regulation of biosynthetic process
1.30 1.24e-04 GO:0009893 positive regulation of metabolic process
1.30 2.36e-04 GO:0031325 positive regulation of cellular metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
2.58 8.92e-04 GO:0000118 histone deacetylase complex
1.85 2.32e-02 GO:0016585 chromatin remodeling complex
1.42 2.08e-06 GO:0044451 nucleoplasm part
1.40 1.68e-11 GO:0005654 nucleoplasm
1.30 6.24e-09 GO:0031981 nuclear lumen
1.28 1.44e-09 GO:0044428 nuclear part
1.25 1.22e-07 GO:0070013 intracellular organelle lumen
1.24 2.08e-07 GO:0043233 organelle lumen
1.24 2.71e-07 GO:0031974 membrane-enclosed lumen
1.23 7.05e-06 GO:0005829 cytosol
1.16 1.51e-05 GO:0032991 macromolecular complex
1.16 9.43e-04 GO:0043234 protein complex
1.15 9.68e-10 GO:0044422 organelle part
1.15 3.35e-09 GO:0005634 nucleus
1.15 5.18e-09 GO:0044446 intracellular organelle part
1.12 1.25e-13 GO:0043231 intracellular membrane-bounded organelle
1.12 1.27e-13 GO:0043227 membrane-bounded organelle
1.12 2.19e-11 GO:0005737 cytoplasm
1.11 1.36e-05 GO:0044444 cytoplasmic part
1.10 2.41e-18 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.57 1.26e-02 GO:0003713 transcription coactivator activity
1.54 5.36e-05 GO:0003712 transcription cofactor activity
1.54 6.43e-05 GO:0000988 protein binding transcription factor activity
1.54 6.43e-05 GO:0000989 transcription factor binding transcription factor activity
1.45 2.28e-02 GO:0016563 transcription activator activity
1.29 2.63e-02 GO:0019899 enzyme binding
1.28 2.98e-03 GO:0030528 transcription regulator activity
1.28 1.75e-02 GO:0003723 RNA binding
1.15 1.36e-15 GO:0005515 protein binding
1.12 4.20e-02 GO:0003676 nucleic acid binding
1.05 5.17e-03 GO:0005488 binding