Motif ID: TBP.p2

Z-value: 1.216


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_170705345-0.611.1e-02Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_24869945 4.750 NM_006158
 NEFL
neurofilament, light polypeptide
chr13_-_52320774 3.985 NM_002590
NM_032949
 PCDH8

protocadherin 8

chr17_-_10265991 3.209 NM_002472
 MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr6_+_27208763 2.855 NM_021064
 HIST1H2AG
histone cluster 1, H2ag
chr6_-_137857213 2.837 NM_175747
 OLIG3
oligodendrocyte transcription factor 3
chr7_+_127668566 2.780 NM_000230
 LEP
leptin
chr1_-_148124738 2.679 NM_003528
 HIST2H2BE
histone cluster 2, H2be
chr20_-_38751289 2.451 NM_005461
 MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr11_-_2863536 2.440 NM_000076
NM_001122630
NM_001122631
 CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr21_-_42608774 2.433 NM_003226
 TFF3
trefoil factor 3 (intestinal)
chr15_-_61461127 2.428 NM_001218
NM_206925
 CA12

carbonic anhydrase XII

chr12_-_51173238 2.408 NM_005554
 KRT6A
keratin 6A
chr11_+_43920385 2.400 NM_001145033
 C11orf96
chromosome 11 open reading frame 96
chr5_-_153837975 2.392 HAND1
heart and neural crest derivatives expressed 1
chr19_-_18763077 2.375 NM_000095
 COMP
cartilage oligomeric matrix protein
chr1_+_150997129 2.358 NM_001025231
 KPRP
keratinocyte proline-rich protein
chr11_+_60391590 2.330 NM_207341
 ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr1_+_17507276 2.299 NM_012387
 PADI4
peptidyl arginine deiminase, type IV
chr6_+_27222839 2.281 NM_080596
 HIST1H2AH
histone cluster 1, H2ah
chr15_+_60146467 2.269 NM_207322
 C2CD4A
C2 calcium-dependent domain containing 4A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 72 entries
enrichment   p-value GO term description
17.39 4.66e-03 GO:0042738 exogenous drug catabolic process
13.91 1.98e-02 GO:0042737 drug catabolic process
13.91 1.98e-02 GO:0046689 response to mercury ion
12.37 1.19e-04 GO:0042744 hydrogen peroxide catabolic process
11.92 9.30e-08 GO:0070301 cellular response to hydrogen peroxide
11.59 5.50e-06 GO:0042743 hydrogen peroxide metabolic process
11.13 3.23e-04 GO:0045103 intermediate filament-based process
9.94 8.30e-09 GO:0034614 cellular response to reactive oxygen species
9.82 2.79e-02 GO:0045104 intermediate filament cytoskeleton organization
9.27 1.27e-07 GO:0031424 keratinization
8.38 7.68e-16 GO:0006334 nucleosome assembly
7.95 3.66e-15 GO:0031497 chromatin assembly
7.83 1.40e-15 GO:0034728 nucleosome organization
7.65 1.38e-04 GO:0072593 reactive oxygen species metabolic process
7.28 4.75e-14 GO:0065004 protein-DNA complex assembly
7.14 2.27e-14 GO:0071824 protein-DNA complex subunit organization
6.96 2.50e-06 GO:0034599 cellular response to oxidative stress
6.42 8.31e-06 GO:0042542 response to hydrogen peroxide
6.18 4.74e-02 GO:0044236 multicellular organismal metabolic process
6.09 7.23e-12 GO:0006323 DNA packaging

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
12.87 1.71e-30 GO:0045095 keratin filament
12.56 2.01e-22 GO:0000786 nucleosome
12.37 1.50e-05 GO:0032982 myosin filament
11.59 7.37e-03 GO:0005833 hemoglobin complex
10.50 2.95e-46 GO:0005882 intermediate filament
9.27 1.03e-03 GO:0001533 cornified envelope
9.08 9.48e-42 GO:0045111 intermediate filament cytoskeleton
8.03 3.39e-16 GO:0032993 protein-DNA complex
3.77 4.23e-31 GO:0005615 extracellular space
3.70 3.24e-08 GO:0000785 chromatin
3.42 5.39e-33 GO:0044421 extracellular region part
3.12 4.50e-02 GO:0030016 myofibril
2.89 1.80e-03 GO:0030141 stored secretory granule
2.85 9.79e-07 GO:0031012 extracellular matrix
2.74 7.16e-05 GO:0005578 proteinaceous extracellular matrix
2.52 2.20e-32 GO:0005576 extracellular region
2.19 1.54e-09 GO:0044430 cytoskeletal part
2.07 7.94e-03 GO:0044427 chromosomal part
2.00 1.31e-10 GO:0005856 cytoskeleton
1.65 2.05e-09 GO:0043228 non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
22.26 2.49e-03 GO:0046870 cadmium ion binding
13.91 3.21e-02 GO:0015250 water channel activity
12.84 8.51e-04 GO:0005344 oxygen transporter activity
7.42 9.98e-06 GO:0019825 oxygen binding
7.26 1.31e-05 GO:0008009 chemokine activity
6.55 4.55e-05 GO:0042379 chemokine receptor binding
6.18 9.10e-10 GO:0005179 hormone activity
5.82 4.85e-03 GO:0008307 structural constituent of muscle
5.73 4.99e-02 GO:0004601 peroxidase activity
5.73 4.99e-02 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor
5.49 4.45e-05 GO:0005200 structural constituent of cytoskeleton
5.03 1.01e-13 GO:0005125 cytokine activity
4.91 2.04e-02 GO:0016209 antioxidant activity
4.52 3.06e-06 GO:0020037 heme binding
4.46 1.69e-06 GO:0046906 tetrapyrrole binding
4.06 9.63e-08 GO:0005126 cytokine receptor binding
3.83 3.45e-02 GO:0005201 extracellular matrix structural constituent
3.68 5.45e-05 GO:0008083 growth factor activity
3.55 4.35e-20 GO:0005198 structural molecule activity
3.40 2.08e-04 GO:0001664 G-protein-coupled receptor binding