Motif ID: ETS1,2.p2

Z-value: 0.916


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ETS1chr11_-_1278972710.647.6e-03Click!
ETS2chr21_+_391170640.495.6e-02Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_88707299 3.115 NM_024756
MMRN2
multimerin 2
chr3_-_184756101 2.531 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr3_-_123223658 2.362 NM_175924
ILDR1
immunoglobulin-like domain containing receptor 1
chr19_-_61324456 2.195 NM_001002836
ZNF787
zinc finger protein 787
chr4_+_2783764 2.089 SH3BP2
SH3-domain binding protein 2
chr1_+_155130146 1.974 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr17_+_7549138 1.970 NM_001406
EFNB3
ephrin-B3
chr5_+_180582905 1.961 NM_033549
NM_201627
TRIM41

tripartite motif containing 41

chr14_-_37795290 1.919 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr18_+_21967813 1.881 NM_001025096
NM_001025097
NM_144662
PSMA8


proteasome (prosome, macropain) subunit, alpha type, 8


chr19_+_52451570 1.818 NM_015603
CCDC9
coiled-coil domain containing 9
chr22_+_35586950 1.805 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr10_+_129595289 1.785 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr12_-_6103945 1.761 NM_000552
VWF
von Willebrand factor
chr19_+_52451642 1.753 CCDC9
coiled-coil domain containing 9
chr10_+_129595349 1.741 PTPRE
protein tyrosine phosphatase, receptor type, E
chr16_+_2145810 1.732 TRAF7
TNF receptor-associated factor 7
chr16_-_65818401 1.684 NM_001004055
LRRC29
leucine rich repeat containing 29
chr1_-_1300680 1.648 NM_017900
AURKAIP1
aurora kinase A interacting protein 1
chr3_+_120799411 1.538 NM_015900
PLA1A
phospholipase A1 member A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
3.70 3.48e-02 GO:0050853 B cell receptor signaling pathway
2.39 1.91e-04 GO:0050851 antigen receptor-mediated signaling pathway
2.27 2.64e-02 GO:0050852 T cell receptor signaling pathway
2.23 8.30e-04 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.21 2.39e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.76 1.16e-02 GO:0051249 regulation of lymphocyte activation
1.75 4.67e-03 GO:0002694 regulation of leukocyte activation
1.75 6.32e-03 GO:0030168 platelet activation
1.73 4.85e-03 GO:0050865 regulation of cell activation
1.62 3.09e-05 GO:0001775 cell activation
1.55 3.58e-03 GO:0002684 positive regulation of immune system process
1.55 3.73e-03 GO:0050776 regulation of immune response
1.53 2.67e-06 GO:0006955 immune response
1.47 4.48e-04 GO:0002682 regulation of immune system process
1.44 1.32e-07 GO:0002376 immune system process
1.32 2.06e-06 GO:0048583 regulation of response to stimulus
1.28 1.54e-02 GO:0009966 regulation of signal transduction
1.18 2.78e-03 GO:0007165 signal transduction

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.45 1.89e-02 GO:0030695 GTPase regulator activity
1.44 2.38e-02 GO:0060589 nucleoside-triphosphatase regulator activity