Motif ID: FEV.p2

Z-value: 2.182


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_2195585170.097.3e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_35586950 2.554 NM_000631
NM_013416
 NCF4

neutrophil cytosolic factor 4, 40kDa

chr10_+_49562866 2.271 WDFY4
WDFY family member 4
chr7_+_106292975 2.235 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_106292932 2.122 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_+_114733907 2.088 NM_017699
 SIDT1
SID1 transmembrane family, member 1
chr10_-_98021144 1.980 NM_001114094
NM_013314
 BLNK

B-cell linker

chr3_-_122862391 1.936 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_122862447 1.897 NM_005335
 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr12_-_6668880 1.814 NM_001039917
NM_001039919
NM_001039920
NM_001135734
 ZNF384



zinc finger protein 384



chr3_+_120495906 1.813 NM_020754
 ARHGAP31
Rho GTPase activating protein 31
chr3_-_46224791 1.803 NM_001295
 CCR1
chemokine (C-C motif) receptor 1
chr7_+_106293112 1.744 NM_002649
 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr12_-_6668680 1.697 ZNF384
zinc finger protein 384
chr11_+_63498590 1.603 NM_004074
 COX8A
cytochrome c oxidase subunit VIIIA (ubiquitous)
chr12_-_6668787 1.584 NM_001039918
NM_133476
 ZNF384

zinc finger protein 384

chr6_-_42527760 1.583 NM_033502
 TRERF1
transcriptional regulating factor 1
chr18_-_59137488 1.566 NM_000633
NM_000657
 BCL2

B-cell CLL/lymphoma 2

chr19_-_61324456 1.555 NM_001002836
 ZNF787
zinc finger protein 787
chr17_-_16816113 1.517 NM_012452
 TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr1_+_32512298 1.511 NM_001042771
 LCK
lymphocyte-specific protein tyrosine kinase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 58 entries
enrichment   p-value GO term description
3.01 1.79e-03 GO:0030890 positive regulation of B cell proliferation
2.92 6.68e-05 GO:0030888 regulation of B cell proliferation
2.79 3.45e-02 GO:0050690 regulation of defense response to virus by virus
2.70 6.15e-04 GO:0050871 positive regulation of B cell activation
2.29 3.58e-03 GO:0050864 regulation of B cell activation
2.24 1.44e-05 GO:0050851 antigen receptor-mediated signaling pathway
2.19 1.46e-03 GO:0050852 T cell receptor signaling pathway
2.15 1.84e-05 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.14 3.06e-02 GO:0031294 lymphocyte costimulation
2.14 3.06e-02 GO:0031295 T cell costimulation
2.12 7.09e-03 GO:0050671 positive regulation of lymphocyte proliferation
2.11 1.26e-04 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.10 1.05e-02 GO:0032946 positive regulation of mononuclear cell proliferation
2.08 2.68e-04 GO:0050670 regulation of lymphocyte proliferation
2.07 1.55e-02 GO:0070665 positive regulation of leukocyte proliferation
2.06 3.93e-04 GO:0032944 regulation of mononuclear cell proliferation
2.05 3.95e-04 GO:0070663 regulation of leukocyte proliferation
2.03 1.83e-07 GO:0051251 positive regulation of lymphocyte activation
1.99 1.77e-07 GO:0002696 positive regulation of leukocyte activation
1.98 1.74e-07 GO:0050867 positive regulation of cell activation

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.73 5.34e-03 GO:0009897 external side of plasma membrane
1.19 3.21e-10 GO:0071944 cell periphery
1.19 5.18e-10 GO:0005886 plasma membrane
1.11 1.07e-05 GO:0044425 membrane part
1.11 7.77e-04 GO:0016021 integral to membrane
1.10 2.63e-07 GO:0016020 membrane
1.10 9.02e-04 GO:0031224 intrinsic to membrane

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.44 9.18e-03 GO:0003823 antigen binding
1.94 4.67e-02 GO:0005089 Rho guanyl-nucleotide exchange factor activity
1.47 1.32e-03 GO:0004984 olfactory receptor activity
1.40 2.32e-06 GO:0004930 G-protein coupled receptor activity
1.36 4.72e-02 GO:0030695 GTPase regulator activity
1.35 4.59e-08 GO:0004888 transmembrane receptor activity
1.34 3.99e-11 GO:0004872 receptor activity
1.33 1.08e-12 GO:0004871 signal transducer activity
1.33 1.08e-12 GO:0060089 molecular transducer activity