Motif ID: SRF.p3

Z-value: 2.379


Transcription factors associated with SRF.p3:

Gene SymbolEntrez IDGene Name
SRF 6722 serum response factor (c-fos serum response element-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SRFchr6_+_432468970.322.3e-01Click!


Activity profile for motif SRF.p3.

activity profile for motif SRF.p3


Sorted Z-values histogram for motif SRF.p3

Sorted Z-values for motif SRF.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of SRF.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_34603311 4.209 MYL9
myosin, light chain 9, regulatory
chr5_+_137829065 4.197 EGR1
early growth response 1
chr20_+_34603290 4.015 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory

chr2_+_73973640 3.370 ACTG2
actin, gamma 2, smooth muscle, enteric
chr5_-_33928049 2.963 ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr9_-_78710698 2.930 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr5_-_33927724 2.540 NM_030955
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr2_+_73973600 2.534 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr5_+_137829077 2.461 NM_001964
EGR1
early growth response 1
chr1_-_89303478 2.254 NM_002053
GBP1
guanylate binding protein 1, interferon-inducible, 67kDa
chr9_+_36126667 2.048 GLIPR2
GLI pathogenesis-related 2
chr15_-_32875040 1.957 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr1_-_166373434 1.822 GPR161
G protein-coupled receptor 161
chr17_-_44026042 1.772 NM_002147
HOXB5
homeobox B5
chr12_+_50731457 1.715 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr17_+_39990124 1.617 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr5_+_60663842 1.612 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr1_-_166373351 1.601 GPR161
G protein-coupled receptor 161
chr9_+_91409746 1.526 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr1_-_166373159 1.509 GPR161
G protein-coupled receptor 161
chr6_+_116939500 1.450 NM_153711
FAM26E
family with sequence similarity 26, member E
chr10_-_131652364 1.447 EBF3
early B-cell factor 3
chr9_+_36126710 1.431 NM_022343
GLIPR2
GLI pathogenesis-related 2
chr17_-_44026321 1.355 HOXB5
homeobox B5
chr2_-_160765008 1.302 ITGB6
integrin, beta 6
chr22_+_29810981 1.289 SMTN
smoothelin
chr1_+_179324458 1.191 IER5
immediate early response 5
chr15_-_63147350 1.177 NM_016563
RASL12
RAS-like, family 12
chr1_-_89261021 1.149 NM_018284
GBP3
guanylate binding protein 3
chr4_+_81337663 1.095 NM_001099403
PRDM8
PR domain containing 8
chr18_-_42804531 1.072 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr19_-_15204767 1.064 NM_001142886
EPHX3
epoxide hydrolase 3
chr1_-_227636462 1.062 NM_001100
ACTA1
actin, alpha 1, skeletal muscle
chr10_-_16899342 1.048 RSU1
Ras suppressor protein 1
chr7_-_27149750 1.045 NM_019102
HOXA5
homeobox A5
chr9_+_18464090 1.037 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr5_+_92944680 1.000 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_-_206151055 0.995 NM_001025109
NM_001773
CD34

CD34 molecule

chr11_-_118799058 0.929 THY1
Thy-1 cell surface antigen
chr3_-_46879883 0.911 NM_000258
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr20_-_42249146 0.880 JPH2
junctophilin 2
chr10_+_112247614 0.876 NM_004419
DUSP5
dual specificity phosphatase 5
chr19_-_40939756 0.859 NM_144617
HSPB6
heat shock protein, alpha-crystallin-related, B6
chr8_-_22606653 0.849 NM_004430
EGR3
early growth response 3
chr3_+_150675117 0.842 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chr2_-_151052391 0.825 NM_005168
RND3
Rho family GTPase 3
chr11_+_116575249 0.806 NM_001001522
NM_003186
TAGLN

transgelin

chr6_-_105691675 0.801 BVES
blood vessel epicardial substance
chr16_+_69215395 0.792 NM_001172772
IL34
interleukin 34
chr9_+_139892049 0.764 NM_000718
CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr18_-_42804291 0.760 NM_001100817
TCEB3C
TCEB3CL
transcription elongation factor B polypeptide 3C (elongin A3)
transcription elongation factor B polypeptide 3C-like
chr10_-_90702490 0.760 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr2_-_40593074 0.760 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr18_-_42810446 0.751 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr19_+_977608 0.746 CNN2
calponin 2
chrX_-_99873728 0.733 NM_001129896
SYTL4
synaptotagmin-like 4
chr11_-_65424434 0.727 FOSL1
FOS-like antigen 1
chr2_-_128149112 0.721 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr3_+_189413414 0.711 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chrX_-_10761729 0.707 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr10_-_29963906 0.698 NM_021738
SVIL
supervillin
chr12_+_52713098 0.687 NM_018953
HOXC5
homeobox C5
chr6_-_109882116 0.681 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr11_-_65424436 0.680 NM_005438
FOSL1
FOS-like antigen 1
chr5_-_58331515 0.654 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_-_52487558 0.646 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr11_-_65424385 0.641 FOSL1
FOS-like antigen 1
chr17_-_1336073 0.640 MYO1C
myosin IC
chr4_+_109033868 0.633 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr22_-_35114001 0.620 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr19_+_12996368 0.619 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr10_+_88418243 0.617 NM_001080116
NM_001080114
NM_001080115
NM_001171611
NM_007078
LDB3




LIM domain binding 3




chr19_+_977582 0.615 CNN2
calponin 2
chr7_-_5536783 0.614 ACTB
actin, beta
chr19_+_2427122 0.599 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr15_-_63147228 0.595 RASL12
RAS-like, family 12
chr19_+_16039170 0.588 NM_001145160
TPM4
tropomyosin 4
chr6_-_117256890 0.576 NM_148963
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr15_+_94674849 0.575 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr7_+_142788521 0.575 ZYX
zyxin
chr7_+_142788480 0.567 NM_001010972
NM_003461
ZYX

zyxin

chr12_-_90029672 0.553 NM_002345
LUM
lumican
chr2_-_160764819 0.551 NM_000888
ITGB6
integrin, beta 6
chr19_+_977601 0.551 CNN2
calponin 2
chr6_+_151603201 0.550 AKAP12
A kinase (PRKA) anchor protein 12
chr2_-_215956429 0.549 FN1
fibronectin 1
chr11_+_59564323 0.533 NM_173801
PLAC1L
placenta-specific 1-like
chr3_+_150675169 0.526 TM4SF4
transmembrane 4 L six family member 4
chr3_-_158704056 0.515 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr19_+_977624 0.513 CNN2
calponin 2
chr6_+_151602787 0.510 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr19_+_977555 0.508 CNN2
calponin 2
chr19_+_50663089 0.504 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr1_-_16217025 0.503 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr7_+_142788569 0.499 ZYX
zyxin
chr14_+_74815233 0.498 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr17_+_30498948 0.498 NM_001033576
NM_173167
UNC45B

unc-45 homolog B (C. elegans)

chr5_+_149526533 0.496 NM_001804
CDX1
caudal type homeobox 1
chr7_+_142788517 0.496 ZYX
zyxin
chr14_+_73775927 0.490 NM_182894
VSX2
visual system homeobox 2
chr7_+_142788566 0.488 ZYX
zyxin
chr17_-_4831388 0.487 NM_001171167
NM_001171168
CAMTA2

calmodulin binding transcription activator 2

chr7_-_80386602 0.486 NM_006379
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr15_+_72006015 0.482 LOXL1
lysyl oxidase-like 1
chr1_-_11830328 0.480 NM_006172
NPPA
natriuretic peptide A
chr16_+_31390567 0.473 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr7_-_107430566 0.461 NM_002291
LAMB1
laminin, beta 1
chr11_-_47330797 0.456 NM_000256
MYBPC3
myosin binding protein C, cardiac
chr11_+_74950893 0.456 SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr22_+_36334811 0.453 GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr4_-_88669625 0.430 NM_001128310
NM_004684
SPARCL1

SPARC-like 1 (hevin)

chr17_-_36456949 0.427 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr10_-_64246080 0.424 EGR2
early growth response 2
chr1_-_206151002 0.411 CD34
CD34 molecule
chr19_-_52666886 0.410 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr5_+_140730014 0.399 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr10_-_16899395 0.394 RSU1
Ras suppressor protein 1
chr7_-_5536704 0.393 NM_001101
ACTB
actin, beta
chrX_-_37591760 0.392 NM_006520
DYNLT3
dynein, light chain, Tctex-type 3
chr22_+_36334400 0.392 NM_001001560
NM_001001561
NM_001172687
NM_013365
GGA1



golgi-associated, gamma adaptin ear containing, ARF binding protein 1



chr21_-_27139143 0.388 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr5_-_141981083 0.386 NM_001144892
FGF1
fibroblast growth factor 1 (acidic)
chr17_-_4831644 0.384 NM_001171166
NM_015099
CAMTA2

calmodulin binding transcription activator 2

chr7_-_80386258 0.377 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_+_94123612 0.376 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr1_-_2451543 0.374 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr13_-_77447664 0.359 NM_000115
EDNRB
endothelin receptor type B
chr10_+_31650069 0.359 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr2_+_26768894 0.354 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr7_+_142788579 0.353 ZYX
zyxin
chr2_-_105381855 0.352 NM_001039492
NM_001450
NM_201555
FHL2


four and a half LIM domains 2


chr2_+_42128521 0.345 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr2_+_100545827 0.342 NM_024065
PDCL3
phosducin-like 3
chr12_+_8167494 0.336 NM_016184
NM_194447
NM_194448
NM_194450
CLEC4A



C-type lectin domain family 4, member A



chr22_+_24468110 0.325 NM_032608
MYO18B
myosin XVIIIB
chr19_+_59064471 0.322 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr22_+_36334622 0.317 GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr7_-_526005 0.315 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr1_-_148080888 0.308 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr19_+_12995782 0.307 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr9_-_4290028 0.305 NM_001042413
GLIS3
GLIS family zinc finger 3
chr19_-_50975603 0.304 NM_001081563
DMPK
dystrophia myotonica-protein kinase
chr2_+_46560207 0.303 NM_001145051
LOC388946
transmembrane protein ENSP00000343375
chr7_+_142788730 0.300 ZYX
zyxin
chr4_+_86918882 0.298 ARHGAP24
Rho GTPase activating protein 24
chr1_+_15957832 0.298 NM_017556
FBLIM1
filamin binding LIM protein 1
chrX_-_37591703 0.298 DYNLT3
dynein, light chain, Tctex-type 3
chr12_-_11439752 0.294 NM_006248
PRB1
PRB2
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 2
chr15_-_57452357 0.290 MYO1E
myosin IE
chr18_-_63333487 0.288 DSEL
dermatan sulfate epimerase-like
chr2_-_69033515 0.284 NM_182536
GKN2
gastrokine 2
chr3_+_189354167 0.280 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_-_124821868 0.277 MYLK
myosin light chain kinase
chr7_+_134114701 0.277 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr20_-_21442663 0.276 NM_002509
NKX2-2
NK2 homeobox 2
chr18_-_42798364 0.274 NM_001100817
TCEB3C
TCEB3CL
transcription elongation factor B polypeptide 3C (elongin A3)
transcription elongation factor B polypeptide 3C-like
chr4_-_158111995 0.271 NM_016205
PDGFC
platelet derived growth factor C
chr2_-_31659472 0.270 NM_000348
SRD5A2
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
chr2_+_28469172 0.265 FOSL2
FOS-like antigen 2
chr2_+_84986273 0.265 NM_021103
TMSB10
thymosin beta 10
chr14_+_104338423 0.243 ZBTB42
zinc finger and BTB domain containing 42
chr4_-_88669267 0.238 SPARCL1
SPARC-like 1 (hevin)
chr7_+_94123672 0.237 PEG10
paternally expressed 10
chr4_+_156899575 0.237 NM_000857
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr19_-_50517971 0.237 CKM
creatine kinase, muscle
chr11_-_8982107 0.230 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr17_-_77094426 0.229 ACTG1
actin, gamma 1
chr19_+_977627 0.227 CNN2
calponin 2
chr4_+_14985272 0.226 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr16_-_66535457 0.226 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr3_+_153014550 0.225 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr12_+_6884157 0.224 NM_001135217
NM_006992
NM_201650
LRRC23


leucine rich repeat containing 23


chr5_-_39461054 0.224 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_-_68177244 0.223 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr11_+_65945050 0.222 NM_178864
NPAS4
neuronal PAS domain protein 4
chr6_+_43246897 0.221 NM_003131
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr7_-_5535726 0.220 ACTB
actin, beta
chr3_+_62279707 0.217 C3orf14
chromosome 3 open reading frame 14
chr17_+_3326045 0.216 NM_000049
ASPA
aspartoacylase
chr14_-_104507862 0.216 AHNAK2
AHNAK nucleoprotein 2
chr5_+_88220846 0.212


chr14_+_62740878 0.212 NM_020663
RHOJ
ras homolog gene family, member J
chr2_-_73373956 0.211 NM_001965
EGR4
early growth response 4
chr17_+_38256710 0.210 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr22_+_28206180 0.210 NM_021076
NEFH
neurofilament, heavy polypeptide
chr1_+_113064711 0.209 NM_001004440
NM_182759
FAM19A3

family with sequence similarity 19 (chemokine (C-C motif)-like), member A3

chr10_+_63950212 0.208 NM_199452
ZNF365
zinc finger protein 365
chr5_-_150264696 0.207 NM_001172831
NM_001172832
NM_052860
ZNF300


zinc finger protein 300


chr19_-_50518072 0.202 NM_001824
CKM
creatine kinase, muscle
chr8_+_24827173 0.202 NM_005382
NEFM
neurofilament, medium polypeptide
chr7_-_94123413 0.200 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr2_-_160972606 0.199 RBMS1
RNA binding motif, single stranded interacting protein 1
chr4_+_120276386 0.199 NM_016599
MYOZ2
myozenin 2
chr10_-_44794146 0.198 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr2_-_96174865 0.193 NM_004418
DUSP2
dual specificity phosphatase 2
chr22_+_24468168 0.192 MYO18B
myosin XVIIIB
chr1_-_240228987 0.191 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr3_-_158695832 0.190 NM_001167917
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr19_+_62566690 0.187 NM_173631
TRAPPC2P1
ZNF547
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
chr10_+_6226884 0.187 PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
8.02 7.13e-10 GO:0003012 muscle system process
8.29 1.49e-09 GO:0006936 muscle contraction
1.80 2.47e-06 GO:0032502 developmental process
1.85 3.65e-06 GO:0007275 multicellular organismal development
1.62 4.96e-06 GO:0032501 multicellular organismal process
4.84 1.60e-05 GO:0030029 actin filament-based process
1.85 2.44e-05 GO:0048856 anatomical structure development
3.17 7.14e-05 GO:0010628 positive regulation of gene expression
1.84 2.05e-04 GO:0048731 system development
5.25 4.83e-04 GO:0007517 muscle organ development
2.59 5.23e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
10.82 6.33e-04 GO:0030048 actin filament-based movement
2.82 7.55e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.26 1.22e-03 GO:0061061 muscle structure development
2.74 1.37e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.77 1.72e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
2.00 1.81e-03 GO:0048513 organ development
5.97 2.35e-03 GO:0034329 cell junction assembly
5.38 6.51e-03 GO:0034330 cell junction organization
2.51 7.15e-03 GO:0009891 positive regulation of biosynthetic process
2.82 7.84e-03 GO:0045893 positive regulation of transcription, DNA-dependent
4.13 8.23e-03 GO:0030036 actin cytoskeleton organization
2.06 9.20e-03 GO:0009653 anatomical structure morphogenesis
1.73 1.16e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
11.18 1.36e-02 GO:0030049 muscle filament sliding
11.18 1.36e-02 GO:0033275 actin-myosin filament sliding
2.46 1.49e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.85 1.57e-02 GO:0030154 cell differentiation
10.89 1.60e-02 GO:0070252 actin-mediated cell contraction
2.13 1.80e-02 GO:0009893 positive regulation of metabolic process
2.52 2.14e-02 GO:0007155 cell adhesion
2.52 2.14e-02 GO:0022610 biological adhesion
2.63 2.40e-02 GO:0051254 positive regulation of RNA metabolic process
8.05 2.43e-02 GO:0008360 regulation of cell shape
1.67 2.89e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.80 3.27e-02 GO:0048869 cellular developmental process
2.13 3.31e-02 GO:0031325 positive regulation of cellular metabolic process
2.90 3.36e-02 GO:0007010 cytoskeleton organization
2.12 4.52e-02 GO:0010604 positive regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
6.99 2.82e-14 GO:0015629 actin cytoskeleton
9.53 4.40e-10 GO:0043292 contractile fiber
2.67 1.28e-09 GO:0005856 cytoskeleton
9.76 1.35e-09 GO:0044449 contractile fiber part
9.51 2.04e-09 GO:0030016 myofibril
9.15 3.00e-07 GO:0030017 sarcomere
16.71 3.24e-06 GO:0042641 actomyosin
10.77 4.77e-06 GO:0016459 myosin complex
17.24 2.07e-05 GO:0001725 stress fiber
16.09 3.47e-05 GO:0032432 actin filament bundle
7.66 3.57e-05 GO:0005925 focal adhesion
7.29 5.93e-05 GO:0005924 cell-substrate adherens junction
7.02 8.71e-05 GO:0030055 cell-substrate junction
1.81 9.46e-05 GO:0043228 non-membrane-bounded organelle
1.81 9.46e-05 GO:0043232 intracellular non-membrane-bounded organelle
2.40 2.38e-04 GO:0044430 cytoskeletal part
5.56 3.31e-04 GO:0005912 adherens junction
19.15 8.29e-04 GO:0005859 muscle myosin complex
5.02 9.62e-04 GO:0070161 anchoring junction
17.24 1.46e-03 GO:0016460 myosin II complex
21.21 5.11e-03 GO:0031672 A band
8.62 1.18e-02 GO:0031674 I band
10.14 2.23e-02 GO:0005884 actin filament
3.62 2.44e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.58 1.44e-06 GO:0003779 actin binding
3.20 1.09e-04 GO:0008092 cytoskeletal protein binding
11.22 5.11e-04 GO:0008307 structural constituent of muscle
2.39 5.99e-04 GO:0030528 transcription regulator activity
2.68 2.42e-03 GO:0046983 protein dimerization activity
2.29 2.91e-03 GO:0001071 nucleic acid binding transcription factor activity
2.29 2.91e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
13.79 5.17e-03 GO:0017022 myosin binding
4.96 7.10e-03 GO:0005516 calmodulin binding
6.13 9.71e-03 GO:0003704 specific RNA polymerase II transcription factor activity
2.34 3.93e-02 GO:0043565 sequence-specific DNA binding
1.28 4.11e-02 GO:0005515 protein binding
4.44 4.12e-02 GO:0003774 motor activity