Motif ID: TFDP1.p2

Z-value: 1.508


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFDP1chr13_+_113287588-0.448.8e-02Click!


Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_30636535 4.845 LOC284804
hypothetical protein LOC284804
chr1_+_224317044 4.304 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr7_+_137795719 3.879 TRIM24
tripartite motif containing 24
chr1_-_93199586 3.422 NM_001006605
FAM69A
family with sequence similarity 69, member A
chr2_-_174537354 3.299 SP3
Sp3 transcription factor
chr17_-_16335809 3.101 C17orf76
chromosome 17 open reading frame 76
chr1_+_24944493 3.098 CLIC4
chloride intracellular channel 4
chr3_-_15875932 2.957 NM_015199
ANKRD28
ankyrin repeat domain 28
chr17_-_70690625 2.948 SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr9_-_79835970 2.889 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr18_-_50004458 2.836 MBD2
methyl-CpG binding domain protein 2
chr7_-_150306169 2.783 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr2_+_46623396 2.780 RHOQ
ras homolog gene family, member Q
chr1_+_24944554 2.664 CLIC4
chloride intracellular channel 4
chr1_+_42920683 2.647 YBX1
Y box binding protein 1
chr2_+_85051942 2.644 KCMF1
potassium channel modulatory factor 1
chr17_+_26060617 2.618


chr2_-_174537021 2.583 NM_001017371
SP3
Sp3 transcription factor
chr7_-_28186671 2.511 JAZF1
JAZF zinc finger 1
chr4_+_99401543 2.466 NM_001100426
NM_001100427
NM_001100428
NM_001100429
NM_001100430
NM_021159
RAP1GDS1





RAP1, GTP-GDP dissociation stimulator 1





chr6_+_163756187 2.418 QKI
quaking homolog, KH domain RNA binding (mouse)
chr11_+_34030500 2.417 CAPRIN1
cell cycle associated protein 1
chr6_-_13819463 2.415 RANBP9
RAN binding protein 9
chr15_-_81667169 2.411 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr2_-_210744158 2.373 NM_152519
C2orf67
chromosome 2 open reading frame 67
chr7_-_148212292 2.351 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr7_-_150305933 2.329 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr10_+_22649977 2.257 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr3_-_137953876 2.241 NM_005862
STAG1
stromal antigen 1
chr6_-_18372617 2.234 NM_001134709
NM_003472
DEK

DEK oncogene

chr15_-_73530829 2.213 NM_015477
SIN3A
SIN3 homolog A, transcription regulator (yeast)
chr13_-_100125028 2.191 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr14_-_104706159 2.185 NM_002226
NM_145159
JAG2

jagged 2

chr12_-_103055924 2.183 NM_006166
NFYB
nuclear transcription factor Y, beta
chrX_-_16797895 2.175 NM_001198719
RBBP7
retinoblastoma binding protein 7
chr11_+_85633829 2.172 EED
embryonic ectoderm development
chr2_-_61551403 2.170 USP34
ubiquitin specific peptidase 34
chr2_+_85051687 2.139 NM_020122
KCMF1
potassium channel modulatory factor 1
chr16_+_51722285 2.130 CHD9
chromodomain helicase DNA binding protein 9
chr7_+_137795387 2.116 NM_003852
NM_015905
TRIM24

tripartite motif containing 24

chr1_+_26671548 2.084 HMGN2
high-mobility group nucleosomal binding domain 2
chr10_+_92912676 2.077 PCGF5
polycomb group ring finger 5
chr4_-_78959532 2.065 NM_144571
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr11_+_32870935 2.052 NM_001076786
QSER1
glutamine and serine rich 1
chr6_-_35764588 2.049 FKBP5
FK506 binding protein 5
chr13_-_76499270 2.049 FBXL3
F-box and leucine-rich repeat protein 3
chr6_-_169866011 2.033 NM_018288
NM_133325
PHF10

PHD finger protein 10

chr6_-_13819931 1.991 RANBP9
RAN binding protein 9
chr2_+_149119029 1.974 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr2_+_149118791 1.971 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chrX_-_20194831 1.966 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr7_-_105712646 1.965 NM_005746
NAMPT
nicotinamide phosphoribosyltransferase
chr6_-_86409283 1.959 NM_001159674
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_-_25295076 1.955 KRAS
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr14_-_104705753 1.950 JAG2
jagged 2
chr18_+_17575275 1.920 MIB1
mindbomb homolog 1 (Drosophila)
chr18_-_50004770 1.913 MBD2
methyl-CpG binding domain protein 2
chr1_+_100590595 1.909 NM_003672
NM_033312
NM_033313
CDC14A


CDC14 cell division cycle 14 homolog A (S. cerevisiae)


chr10_+_92970302 1.896 NM_032373
PCGF5
polycomb group ring finger 5
chr4_-_101090431 1.882 H2AFZ
H2A histone family, member Z
chr1_-_32176562 1.874 NM_080391
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr10_+_22650145 1.874 BMI1
BMI1 polycomb ring finger oncogene
chr15_-_58671929 1.867 NM_134262
RORA
RAR-related orphan receptor A
chr1_+_26728846 1.863 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_-_242681860 1.848 NM_001126
ADSS
adenylosuccinate synthase
chr4_-_101090505 1.847 NM_002106
H2AFZ
H2A histone family, member Z
chr12_-_122322117 1.845 NM_004642
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr1_-_51757490 1.843 EPS15
epidermal growth factor receptor pathway substrate 15
chrX_-_109447970 1.809 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr1_+_100590640 1.802 CDC14A
CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr21_+_16024241 1.795 NM_013396
USP25
ubiquitin specific peptidase 25
chr1_-_210070199 1.786 LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr7_-_148212310 1.786 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr16_+_21926939 1.783 NM_001164579
C16orf52
chromosome 16 open reading frame 52
chr4_-_39655554 1.781 PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr11_+_85633908 1.781 EED
embryonic ectoderm development
chr2_-_61551350 1.780 NM_014709
USP34
ubiquitin specific peptidase 34
chr5_+_176493488 1.779 NSD1
nuclear receptor binding SET domain protein 1
chr1_-_242681742 1.767 ADSS
adenylosuccinate synthase
chr3_+_14964080 1.766 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chrX_-_20195062 1.765 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr6_+_135544214 1.760 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr16_+_65620715 1.757 CBFB
core-binding factor, beta subunit
chr11_-_109672401 1.746 NM_002906
RDX
radixin
chr14_-_90596665 1.725 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr3_+_171558143 1.724 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr9_+_107046713 1.713 NM_080546
SLC44A1
solute carrier family 44, member 1
chrX_-_13866565 1.703 NM_001001994
GPM6B
glycoprotein M6B
chr18_-_12874140 1.702 NM_002828
NM_080422
NM_080423
PTPN2


protein tyrosine phosphatase, non-receptor type 2


chr4_+_38341982 1.701 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chrX_-_16798383 1.699 NM_002893
RBBP7
retinoblastoma binding protein 7
chr10_+_92970487 1.697 PCGF5
polycomb group ring finger 5
chr5_-_43592847 1.676 NM_006451
NM_182789
PAIP1

poly(A) binding protein interacting protein 1

chr3_-_187025438 1.668 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr4_+_39734902 1.665 NM_018177
N4BP2
NEDD4 binding protein 2
chr3_+_171558188 1.658 SKIL
SKI-like oncogene
chr6_-_35764655 1.658 NM_001145776
NM_001145777
NM_004117
FKBP5


FK506 binding protein 5


chr4_-_83570318 1.656 NM_031372
HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr17_-_70690688 1.653 NM_001005849
NM_006937
SUMO2

SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)

chr18_-_43710917 1.644 NM_005901
SMAD2
SMAD family member 2
chr5_-_40834232 1.641 PRKAA1
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr1_+_24944346 1.641 NM_013943
CLIC4
chloride intracellular channel 4
chr21_-_39607288 1.639 BRWD1
bromodomain and WD repeat domain containing 1
chr12_+_44409762 1.621 NM_152641
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr11_+_34030527 1.620 CAPRIN1
cell cycle associated protein 1
chr17_-_70690664 1.613 SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr3_-_53054325 1.610 NM_001005159
SFMBT1
Scm-like with four mbt domains 1
chr3_+_171558215 1.610 SKIL
SKI-like oncogene
chr12_-_54869568 1.606 NM_001130420
NM_003075
NM_139067
SMARCC2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr6_+_163755773 1.606 QKI
quaking homolog, KH domain RNA binding (mouse)
chr2_-_171725150 1.604 TLK1
tousled-like kinase 1
chr16_-_29532538 1.599


chr12_+_67290881 1.591 NM_001010942
NM_015646
RAP1B

RAP1B, member of RAS oncogene family

chr12_-_40918249 1.591 NM_001190977
YAF2
YY1 associated factor 2
chr7_+_77004686 1.579 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr11_-_75769514 1.573 NM_004705
PRKRIR
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr5_+_176493233 1.568 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr1_+_26728827 1.562 NM_002953
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_-_110521250 1.556 ATXN2
ataxin 2
chr9_+_100907213 1.555 TGFBR1
transforming growth factor, beta receptor 1
chr7_+_138695537 1.554 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr8_+_95977135 1.553 C8orf38
chromosome 8 open reading frame 38
chr4_-_15266042 1.550 FBXL5
F-box and leucine-rich repeat protein 5
chr1_-_224563820 1.546 NM_173083
LIN9
lin-9 homolog (C. elegans)
chr17_+_2153969 1.545 NM_021947
SRR
serine racemase
chr8_+_95904693 1.534 NM_017864
INTS8
integrator complex subunit 8
chr1_-_32574185 1.534 NM_023009
MARCKSL1
MARCKS-like 1
chr1_-_32176475 1.534 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr10_+_105716925 1.532 SLK
STE20-like kinase
chr7_-_22363036 1.530 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr10_-_15250616 1.525 NM_004808
NMT2
N-myristoyltransferase 2
chr9_+_100907222 1.519 NM_001130916
NM_004612
TGFBR1

transforming growth factor, beta receptor 1

chr11_+_85633437 1.517 NM_003797
NM_152991
EED

embryonic ectoderm development

chr9_+_107046811 1.513 SLC44A1
solute carrier family 44, member 1
chr2_-_174538197 1.511 SP3
Sp3 transcription factor
chr3_+_197780105 1.508 NM_001105573
FBXO45
F-box protein 45
chr1_+_26728839 1.500 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr4_+_57468847 1.496 REST
RE1-silencing transcription factor
chr1_-_32176275 1.494 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr8_-_30789865 1.494 NM_001009552
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr6_-_86409354 1.493 NM_001159673
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr18_-_43711452 1.493 NM_001003652
NM_001135937
SMAD2

SMAD family member 2

chr1_+_224317036 1.490 NM_002107
H3F3A
H3 histone, family 3A
chr14_+_31616196 1.486 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr5_+_127447306 1.485 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr8_-_42817604 1.484 NM_018105
NM_199003
THAP1

THAP domain containing, apoptosis associated protein 1

chr5_-_65053630 1.483 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr2_+_153282631 1.481 NM_152522
ARL6IP6
ADP-ribosylation-like factor 6 interacting protein 6
chr10_+_28862429 1.478 NM_016628
NM_100486
WAC

WW domain containing adaptor with coiled-coil

chr11_+_9552027 1.477 WEE1
WEE1 homolog (S. pombe)
chr18_-_43711143 1.474 SMAD2
SMAD family member 2
chr13_-_50925134 1.472 INTS6
integrator complex subunit 6
chr16_+_29725597 1.461


chr10_-_11693535 1.461 NM_014688
USP6NL
USP6 N-terminal like
chr17_+_57909979 1.459 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr5_-_179651664 1.457 NM_001135044
NM_002752
NM_139068
NM_139069
NM_139070
MAPK9




mitogen-activated protein kinase 9




chr6_+_163755658 1.452 NM_006775
NM_206853
NM_206854
NM_206855
QKI



quaking homolog, KH domain RNA binding (mouse)



chr1_+_25629968 1.441 NM_018202
TMEM57
transmembrane protein 57
chr2_-_38457884 1.440 ATL2
atlastin GTPase 2
chr5_-_40834006 1.436 NM_006251
NM_206907
PRKAA1

protein kinase, AMP-activated, alpha 1 catalytic subunit

chr6_+_126153693 1.436 NM_001122842
NM_181782
NCOA7

nuclear receptor coactivator 7

chr3_-_9413336 1.432 LOC440944
hypothetical LOC440944
chr6_+_44346457 1.428 NM_001137560
TMEM151B
transmembrane protein 151B
chr1_+_224317062 1.423 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr1_-_114855281 1.422 NM_015906
NM_033020
TRIM33

tripartite motif containing 33

chr2_-_215382537 1.420 NM_000465
BARD1
BRCA1 associated RING domain 1
chr17_-_28228184 1.419 MYO1D
myosin ID
chr6_+_52550063 1.414 FLJ37798
hypothetical LOC401264
chr1_+_39319675 1.413 NM_012090
MACF1
microtubule-actin crosslinking factor 1
chr11_-_33847834 1.412 LMO2
LIM domain only 2 (rhombotin-like 1)
chr1_-_210070736 1.412 NM_014873
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr16_-_30254189 1.411 LOC595101
PI-3-kinase-related kinase SMG-1 pseudogene
chr1_+_224317056 1.407 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr8_+_61753793 1.402 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr5_-_36277656 1.399 NM_001085411
C5orf33
chromosome 5 open reading frame 33
chr4_-_25473528 1.399 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr17_+_63252087 1.394 NM_004459
NM_182641
BPTF

bromodomain PHD finger transcription factor

chr22_+_33983444 1.391 NM_001003681
HMGXB4
HMG box domain containing 4
chr2_+_208284610 1.391 CCNYL1
cyclin Y-like 1
chr11_+_34030465 1.390 CAPRIN1
cell cycle associated protein 1
chr4_-_17632456 1.388 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr9_+_99303639 1.387 NM_003275
TMOD1
tropomodulin 1
chr3_+_197779878 1.386 FBXO45
F-box protein 45
chr17_+_31975611 1.385 GGNBP2
gametogenetin binding protein 2
chr17_-_60483206 1.379 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr17_+_27288152 1.377 NM_015355
SUZ12
suppressor of zeste 12 homolog (Drosophila)
chr6_-_79844503 1.375 PHIP
pleckstrin homology domain interacting protein
chr3_-_14964620 1.372


chr7_-_148212312 1.370 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr8_+_81560971 1.367 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr16_+_65620610 1.365 CBFB
core-binding factor, beta subunit
chr4_-_15265993 1.363 FBXL5
F-box and leucine-rich repeat protein 5
chr4_+_52403922 1.360 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr5_-_131160541 1.359 FNIP1
folliculin interacting protein 1
chr20_-_55718351 1.359 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_+_65053749 1.358 NM_020726
NLN
neurolysin (metallopeptidase M3 family)
chr12_+_67290975 1.356 RAP1B
RAP1B, member of RAS oncogene family
chr1_+_88922424 1.356 NM_006256
PKN2
protein kinase N2
chr8_-_99906944 1.354 NM_006281
STK3
serine/threonine kinase 3
chr17_-_70690525 1.349 SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.11 6.66e-40 GO:0009987 cellular process
1.27 4.04e-39 GO:0044260 cellular macromolecule metabolic process
1.19 5.56e-33 GO:0044237 cellular metabolic process
1.21 3.64e-28 GO:0043170 macromolecule metabolic process
1.17 4.00e-27 GO:0044238 primary metabolic process
1.15 3.94e-25 GO:0008152 metabolic process
1.36 5.60e-25 GO:0006464 protein modification process
1.30 8.22e-24 GO:0044267 cellular protein metabolic process
1.34 2.41e-22 GO:0043412 macromolecule modification
1.26 7.01e-20 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 9.63e-20 GO:0071842 cellular component organization at cellular level
1.34 1.76e-18 GO:0006996 organelle organization
1.25 2.72e-18 GO:0071841 cellular component organization or biogenesis at cellular level
1.22 5.77e-18 GO:0016043 cellular component organization
1.13 3.02e-17 GO:0050794 regulation of cellular process
1.21 1.13e-16 GO:0071840 cellular component organization or biogenesis
1.22 1.83e-16 GO:0034641 cellular nitrogen compound metabolic process
1.21 6.73e-16 GO:0006807 nitrogen compound metabolic process
1.27 7.24e-16 GO:0090304 nucleic acid metabolic process
1.12 3.61e-15 GO:0050789 regulation of biological process
1.22 4.09e-15 GO:0019538 protein metabolic process
1.37 5.07e-13 GO:0007049 cell cycle
1.48 9.10e-13 GO:0051276 chromosome organization
1.10 1.65e-12 GO:0065007 biological regulation
1.18 8.18e-12 GO:0080090 regulation of primary metabolic process
1.18 1.27e-11 GO:0031323 regulation of cellular metabolic process
1.27 2.19e-11 GO:0016070 RNA metabolic process
1.18 5.17e-11 GO:0060255 regulation of macromolecule metabolic process
1.16 6.29e-11 GO:0019222 regulation of metabolic process
1.23 6.41e-11 GO:0048523 negative regulation of cellular process
1.22 8.21e-11 GO:0044249 cellular biosynthetic process
1.58 8.92e-11 GO:0016568 chromatin modification
1.51 1.66e-10 GO:0006325 chromatin organization
1.26 1.83e-10 GO:0034645 cellular macromolecule biosynthetic process
1.21 2.09e-10 GO:0048522 positive regulation of cellular process
1.21 2.21e-10 GO:0009058 biosynthetic process
1.45 4.53e-10 GO:0000278 mitotic cell cycle
1.21 5.19e-10 GO:0048519 negative regulation of biological process
1.37 8.86e-10 GO:0022402 cell cycle process
1.25 9.53e-10 GO:0009059 macromolecule biosynthetic process
1.45 3.99e-09 GO:0016071 mRNA metabolic process
1.45 8.00e-09 GO:0044265 cellular macromolecule catabolic process
1.39 8.09e-09 GO:0022403 cell cycle phase
1.41 1.04e-08 GO:0051726 regulation of cell cycle
1.18 1.26e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.55 1.47e-08 GO:0070647 protein modification by small protein conjugation or removal
1.27 1.56e-08 GO:0033036 macromolecule localization
1.34 1.77e-08 GO:0016265 death
1.36 1.80e-08 GO:0046907 intracellular transport
1.18 2.14e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 2.16e-08 GO:0008219 cell death
1.40 3.20e-08 GO:0009057 macromolecule catabolic process
1.17 1.21e-07 GO:0048518 positive regulation of biological process
1.32 1.22e-07 GO:0006351 transcription, DNA-dependent
1.19 1.35e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.31 1.44e-07 GO:0032774 RNA biosynthetic process
1.57 1.57e-07 GO:0032446 protein modification by small protein conjugation
1.30 2.89e-07 GO:0006793 phosphorus metabolic process
1.30 2.89e-07 GO:0006796 phosphate metabolic process
1.18 3.68e-07 GO:0010468 regulation of gene expression
1.29 3.73e-07 GO:0032268 regulation of cellular protein metabolic process
1.26 3.81e-07 GO:0051641 cellular localization
1.28 7.97e-07 GO:0008104 protein localization
1.22 1.18e-06 GO:0023051 regulation of signaling
1.24 1.71e-06 GO:0009966 regulation of signal transduction
1.30 2.11e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.28 2.62e-06 GO:0009892 negative regulation of metabolic process
1.66 2.72e-06 GO:0016569 covalent chromatin modification
1.30 3.39e-06 GO:0031324 negative regulation of cellular metabolic process
1.17 3.52e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.33 4.00e-06 GO:0012501 programmed cell death
1.55 4.32e-06 GO:0016567 protein ubiquitination
1.65 4.93e-06 GO:0016570 histone modification
1.20 5.42e-06 GO:0010467 gene expression
1.33 6.52e-06 GO:0006915 apoptosis
1.26 6.98e-06 GO:0051246 regulation of protein metabolic process
1.25 7.28e-06 GO:0044248 cellular catabolic process
1.35 7.49e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.17 7.86e-06 GO:0051252 regulation of RNA metabolic process
1.16 1.06e-05 GO:0031326 regulation of cellular biosynthetic process
1.33 1.16e-05 GO:0009890 negative regulation of biosynthetic process
1.49 1.41e-05 GO:0051325 interphase
1.33 1.71e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.15 1.83e-05 GO:0009889 regulation of biosynthetic process
1.33 2.23e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.48 2.60e-05 GO:0051329 interphase of mitotic cell cycle
1.33 2.73e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.28 3.59e-05 GO:0045184 establishment of protein localization
1.42 4.30e-05 GO:0006397 mRNA processing
1.37 4.44e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.21 5.01e-05 GO:0009653 anatomical structure morphogenesis
1.13 5.19e-05 GO:0051179 localization
1.44 5.57e-05 GO:0051301 cell division
1.33 7.84e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 9.03e-05 GO:0051649 establishment of localization in cell
1.45 9.14e-05 GO:0019941 modification-dependent protein catabolic process
1.42 1.02e-04 GO:0030163 protein catabolic process
1.87 1.05e-04 GO:0006402 mRNA catabolic process
1.45 1.24e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.21 1.49e-04 GO:0035556 intracellular signal transduction
1.27 1.60e-04 GO:0015031 protein transport
1.44 1.60e-04 GO:0043632 modification-dependent macromolecule catabolic process
1.29 1.62e-04 GO:0006468 protein phosphorylation
1.27 1.92e-04 GO:0051128 regulation of cellular component organization
1.32 1.92e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.43 2.25e-04 GO:0051603 proteolysis involved in cellular protein catabolic process
1.27 2.40e-04 GO:0033554 cellular response to stress
1.16 2.83e-04 GO:0006355 regulation of transcription, DNA-dependent
1.42 3.13e-04 GO:0044257 cellular protein catabolic process
1.25 4.19e-04 GO:0022008 neurogenesis
1.22 4.30e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.24 4.74e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.67 6.13e-04 GO:0006403 RNA localization
1.27 6.67e-04 GO:0031399 regulation of protein modification process
1.13 7.52e-04 GO:0051234 establishment of localization
1.43 7.68e-04 GO:0008380 RNA splicing
1.21 8.50e-04 GO:0009893 positive regulation of metabolic process
1.40 9.61e-04 GO:0018193 peptidyl-amino acid modification
1.55 9.71e-04 GO:0051169 nuclear transport
1.56 1.07e-03 GO:0006913 nucleocytoplasmic transport
1.11 1.26e-03 GO:0032502 developmental process
1.83 1.31e-03 GO:0000956 nuclear-transcribed mRNA catabolic process
1.92 1.42e-03 GO:0031124 mRNA 3'-end processing
1.21 1.63e-03 GO:0031325 positive regulation of cellular metabolic process
1.66 1.88e-03 GO:0050657 nucleic acid transport
1.66 1.88e-03 GO:0050658 RNA transport
1.66 1.88e-03 GO:0051236 establishment of RNA localization
1.32 1.90e-03 GO:0070727 cellular macromolecule localization
1.63 2.08e-03 GO:0006470 protein dephosphorylation
1.25 2.27e-03 GO:0016310 phosphorylation
1.29 2.43e-03 GO:0010629 negative regulation of gene expression
1.32 2.79e-03 GO:0034613 cellular protein localization
1.28 2.98e-03 GO:0030030 cell projection organization
1.18 3.58e-03 GO:0009056 catabolic process
1.12 3.62e-03 GO:0006810 transport
1.12 3.69e-03 GO:0048856 anatomical structure development
1.24 3.84e-03 GO:0048699 generation of neurons
1.27 3.98e-03 GO:0019220 regulation of phosphate metabolic process
1.27 3.98e-03 GO:0051174 regulation of phosphorus metabolic process
1.41 4.05e-03 GO:0000280 nuclear division
1.41 4.05e-03 GO:0006366 transcription from RNA polymerase II promoter
1.41 4.05e-03 GO:0007067 mitosis
1.47 4.09e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.18 4.56e-03 GO:0007399 nervous system development
1.67 4.69e-03 GO:0006401 RNA catabolic process
1.31 4.93e-03 GO:0006974 response to DNA damage stimulus
1.40 4.95e-03 GO:0000087 M phase of mitotic cell cycle
1.30 5.34e-03 GO:0051253 negative regulation of RNA metabolic process
1.36 6.31e-03 GO:0044419 interspecies interaction between organisms
1.42 6.40e-03 GO:0010608 posttranscriptional regulation of gene expression
1.28 6.53e-03 GO:0006259 DNA metabolic process
1.37 6.61e-03 GO:0010564 regulation of cell cycle process
1.23 6.98e-03 GO:0048468 cell development
1.65 7.27e-03 GO:0051028 mRNA transport
1.57 7.68e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.30 8.52e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.21 8.84e-03 GO:0010646 regulation of cell communication
1.33 9.40e-03 GO:0000279 M phase
1.54 9.82e-03 GO:0071103 DNA conformation change
1.56 1.01e-02 GO:0016311 dephosphorylation
1.11 1.08e-02 GO:0007275 multicellular organismal development
1.39 1.14e-02 GO:0048285 organelle fission
1.30 1.14e-02 GO:0051338 regulation of transferase activity
1.23 1.15e-02 GO:0043933 macromolecular complex subunit organization
1.21 1.32e-02 GO:0042981 regulation of apoptosis
1.76 1.38e-02 GO:0031123 RNA 3'-end processing
1.48 1.39e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.48 1.39e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
1.37 1.43e-02 GO:0033043 regulation of organelle organization
1.17 1.48e-02 GO:0065009 regulation of molecular function
1.27 1.67e-02 GO:0000902 cell morphogenesis
1.20 1.70e-02 GO:0010941 regulation of cell death
1.20 1.86e-02 GO:0043067 regulation of programmed cell death
1.51 2.01e-02 GO:0006417 regulation of translation
1.21 2.10e-02 GO:0042127 regulation of cell proliferation
1.23 2.18e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.30 2.24e-02 GO:0045859 regulation of protein kinase activity
1.26 2.29e-02 GO:0032989 cellular component morphogenesis
1.48 2.30e-02 GO:0006260 DNA replication
1.30 2.41e-02 GO:0043549 regulation of kinase activity
1.20 2.52e-02 GO:0022607 cellular component assembly
1.33 2.92e-02 GO:0007264 small GTPase mediated signal transduction
1.45 3.01e-02 GO:0000375 RNA splicing, via transesterification reactions
1.26 3.13e-02 GO:0001932 regulation of protein phosphorylation
1.29 3.45e-02 GO:0031175 neuron projection development
1.41 3.45e-02 GO:0072523 purine-containing compound catabolic process
1.28 3.99e-02 GO:0043065 positive regulation of apoptosis
1.24 4.06e-02 GO:0065003 macromolecular complex assembly
1.24 4.27e-02 GO:0042325 regulation of phosphorylation
1.23 4.33e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.55 4.47e-02 GO:0051348 negative regulation of transferase activity
1.13 4.68e-02 GO:0048869 cellular developmental process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 1.16e-80 GO:0044424 intracellular part
1.15 3.52e-80 GO:0005622 intracellular
1.16 1.70e-61 GO:0043226 organelle
1.16 4.00e-61 GO:0043229 intracellular organelle
1.18 3.43e-60 GO:0043227 membrane-bounded organelle
1.18 9.46e-60 GO:0043231 intracellular membrane-bounded organelle
1.25 1.11e-51 GO:0005634 nucleus
1.16 1.42e-43 GO:0005737 cytoplasm
1.20 2.15e-31 GO:0044446 intracellular organelle part
1.36 6.74e-31 GO:0044428 nuclear part
1.19 1.13e-29 GO:0044422 organelle part
1.36 1.27e-25 GO:0031981 nuclear lumen
1.16 1.84e-22 GO:0044444 cytoplasmic part
1.31 3.24e-22 GO:0005829 cytosol
1.05 7.94e-22 GO:0044464 cell part
1.05 9.29e-22 GO:0005623 cell
1.29 1.52e-21 GO:0070013 intracellular organelle lumen
1.38 4.70e-20 GO:0005654 nucleoplasm
1.28 6.92e-20 GO:0031974 membrane-enclosed lumen
1.28 8.30e-20 GO:0043233 organelle lumen
1.48 1.16e-12 GO:0005694 chromosome
1.51 1.46e-11 GO:0044427 chromosomal part
1.16 2.40e-10 GO:0032991 macromolecular complex
1.17 2.88e-09 GO:0043234 protein complex
1.18 3.34e-09 GO:0043228 non-membrane-bounded organelle
1.18 3.34e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.22 9.42e-08 GO:0012505 endomembrane system
1.33 2.19e-07 GO:0044451 nucleoplasm part
1.59 8.52e-07 GO:0000228 nuclear chromosome
1.18 8.85e-07 GO:0031090 organelle membrane
1.93 2.15e-06 GO:0000790 nuclear chromatin
1.54 2.26e-06 GO:0000785 chromatin
1.62 4.99e-06 GO:0044454 nuclear chromosome part
1.30 1.84e-05 GO:0015630 microtubule cytoskeleton
1.23 2.22e-04 GO:0005794 Golgi apparatus
1.38 3.20e-04 GO:0005815 microtubule organizing center
1.53 3.30e-04 GO:0031252 cell leading edge
1.43 9.56e-04 GO:0005635 nuclear envelope
1.31 1.05e-03 GO:0000139 Golgi membrane
1.27 2.12e-03 GO:0044431 Golgi apparatus part
2.03 2.36e-03 GO:0008287 protein serine/threonine phosphatase complex
1.53 4.22e-03 GO:0000775 chromosome, centromeric region
1.42 5.01e-03 GO:0005813 centrosome
1.33 5.08e-03 GO:0048471 perinuclear region of cytoplasm
1.69 8.32e-03 GO:0009898 internal side of plasma membrane
1.22 9.80e-03 GO:0031975 envelope
1.22 1.12e-02 GO:0031967 organelle envelope
1.26 1.95e-02 GO:0005730 nucleolus
2.40 2.59e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.48 3.15e-02 GO:0000793 condensed chromosome
1.17 3.43e-02 GO:0005783 endoplasmic reticulum

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 1.43e-52 GO:0005515 protein binding
1.10 6.65e-38 GO:0005488 binding
1.25 3.07e-15 GO:0000166 nucleotide binding
1.16 6.23e-10 GO:0003676 nucleic acid binding
1.61 2.07e-09 GO:0016881 acid-amino acid ligase activity
1.57 4.78e-09 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.64 8.08e-09 GO:0019787 small conjugating protein ligase activity
1.32 1.08e-08 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.11 1.39e-08 GO:0003824 catalytic activity
1.22 5.30e-08 GO:0016740 transferase activity
1.31 3.60e-07 GO:0003723 RNA binding
1.59 7.91e-07 GO:0004842 ubiquitin-protein ligase activity
1.19 1.85e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.19 2.31e-06 GO:0017076 purine nucleotide binding
1.19 2.48e-06 GO:0032553 ribonucleotide binding
1.19 2.48e-06 GO:0032555 purine ribonucleotide binding
1.31 3.71e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.30 5.10e-06 GO:0016301 kinase activity
1.25 1.30e-05 GO:0030528 transcription regulator activity
1.33 1.71e-05 GO:0004672 protein kinase activity
1.38 2.32e-05 GO:0004674 protein serine/threonine kinase activity
1.16 2.70e-05 GO:0003677 DNA binding
1.20 3.06e-05 GO:0030554 adenyl nucleotide binding
1.19 4.16e-05 GO:0032559 adenyl ribonucleotide binding
1.19 5.14e-05 GO:0005524 ATP binding
1.24 8.98e-05 GO:0001071 nucleic acid binding transcription factor activity
1.24 8.98e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.57 3.40e-04 GO:0004721 phosphoprotein phosphatase activity
1.26 4.48e-04 GO:0019899 enzyme binding
1.27 4.63e-04 GO:0043565 sequence-specific DNA binding
1.33 6.37e-04 GO:0016874 ligase activity
1.43 1.88e-03 GO:0016791 phosphatase activity
1.35 6.42e-03 GO:0042578 phosphoric ester hydrolase activity
1.68 7.64e-03 GO:0008565 protein transporter activity
1.24 1.01e-02 GO:0046983 protein dimerization activity
1.30 1.02e-02 GO:0019904 protein domain specific binding
1.32 1.38e-02 GO:0000988 protein binding transcription factor activity
1.32 1.38e-02 GO:0000989 transcription factor binding transcription factor activity
1.31 1.83e-02 GO:0003712 transcription cofactor activity
1.22 1.87e-02 GO:0042802 identical protein binding
1.34 2.33e-02 GO:0016563 transcription activator activity
1.58 4.84e-02 GO:0004725 protein tyrosine phosphatase activity