Motif ID: TFAP4.p2

Z-value: 1.108


Transcription factors associated with TFAP4.p2:

Gene SymbolEntrez IDGene Name
TFAP4 7023 transcription factor AP-4 (activating enhancer binding protein 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFAP4chr16_-_4262696-0.155.7e-01Click!


Activity profile for motif TFAP4.p2.

activity profile for motif TFAP4.p2


Sorted Z-values histogram for motif TFAP4.p2

Sorted Z-values for motif TFAP4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_36436979 1.880 NM_031957
 KRTAP1-5
keratin associated protein 1-5
chr17_-_36451189 1.867 NM_030967
 KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr3_-_87122936 1.237 NM_016206
 VGLL3
vestigial like 3 (Drosophila)
chr3_-_87122958 1.145 VGLL3
vestigial like 3 (Drosophila)
chr17_-_27210330 1.064 NM_018405
 C17orf79
chromosome 17 open reading frame 79
chr5_+_94981735 0.993 NM_199243
 GPR150
G protein-coupled receptor 150
chr17_-_36444626 0.955 NM_030966
 KRTAP1-3
keratin associated protein 1-3
chr6_-_132764257 0.906 NM_015529
 MOXD1
monooxygenase, DBH-like 1
chr1_-_199704773 0.901 NM_012396
 PHLDA3
pleckstrin homology-like domain, family A, member 3
chr17_-_36577949 0.897 NM_033187
 KRTAP4-3
keratin associated protein 4-3
chr11_+_60391590 0.887 NM_207341
 ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr22_-_32646325 0.822 NM_004737
NM_133642
 LARGE

like-glycosyltransferase

chr16_-_4106186 0.791 NM_001116
 ADCY9
adenylate cyclase 9
chr12_-_50871953 0.772 NM_001081492
NM_182507
 KRT80

keratin 80

chr1_+_43769065 0.756 NM_002840
NM_130440
 PTPRF

protein tyrosine phosphatase, receptor type, F

chr8_+_144711619 0.745 NM_024736
 GSDMD
gasdermin D
chr19_-_18912112 0.743 NM_001145722
NM_001145721
 HOMER3

homer homolog 3 (Drosophila)

chr16_-_4106022 0.738 ADCY9
adenylate cyclase 9
chr1_-_6502655 0.724 NM_198681
 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_+_43502301 0.723 NM_004823
 KCNK6
potassium channel, subfamily K, member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
1.72 1.77e-02 GO:0030334 regulation of cell migration
1.70 2.75e-02 GO:2000145 regulation of cell motility
1.67 2.26e-02 GO:0040012 regulation of locomotion
1.53 4.84e-02 GO:0007409 axonogenesis
1.50 2.98e-02 GO:0000904 cell morphogenesis involved in differentiation
1.45 1.35e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.43 4.12e-02 GO:0030030 cell projection organization
1.40 4.26e-03 GO:0022008 neurogenesis
1.39 1.21e-02 GO:0048699 generation of neurons
1.33 2.14e-05 GO:0007166 cell surface receptor linked signaling pathway
1.31 2.04e-03 GO:0007399 nervous system development
1.23 1.20e-06 GO:0023052 signaling
1.23 1.29e-05 GO:0007165 signal transduction
1.21 3.26e-03 GO:0048731 system development
1.18 6.57e-03 GO:0007275 multicellular organismal development
1.17 1.10e-02 GO:0032502 developmental process
1.17 4.54e-02 GO:0048856 anatomical structure development
1.15 3.25e-02 GO:0051716 cellular response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
3.12 2.02e-09 GO:0045095 keratin filament
2.47 1.42e-03 GO:0005604 basement membrane
2.11 1.05e-05 GO:0005882 intermediate filament
2.04 6.35e-03 GO:0044420 extracellular matrix part
2.02 1.04e-05 GO:0045111 intermediate filament cytoskeleton
1.85 1.49e-06 GO:0005578 proteinaceous extracellular matrix
1.77 1.41e-06 GO:0031012 extracellular matrix
1.42 8.21e-06 GO:0044421 extracellular region part
1.35 1.50e-02 GO:0005615 extracellular space
1.30 3.21e-06 GO:0005576 extracellular region
1.25 1.64e-04 GO:0044459 plasma membrane part
1.25 1.11e-02 GO:0005856 cytoskeleton
1.17 2.87e-04 GO:0005886 plasma membrane
1.16 4.97e-04 GO:0071944 cell periphery
1.09 2.99e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.16 4.65e-02 GO:0005201 extracellular matrix structural constituent
2.03 2.23e-02 GO:0019838 growth factor binding
1.40 3.34e-02 GO:0005198 structural molecule activity