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• Activity deltas table
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Motif ID: EWSR1-FLI1.p2

Z-value: 0.732

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_156819604	0.997	NM_001099287 NM_001172292	NIPAL4	NIPA-like domain containing 4
chr20_+_42807901	0.931	NM_022358	KCNK15	potassium channel, subfamily K, member 15
chr5_+_156819782	0.876		NIPAL4	NIPA-like domain containing 4
chr1_-_6468600	0.809	NM_001042665	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr1_-_68071635	0.802	NM_018841	GNG12	guanine nucleotide binding protein (G protein), gamma 12
chr14_-_53493198	0.801	NM_001202 NM_130850	BMP4	bone morphogenetic protein 4
chr1_-_68470585	0.793	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr6_-_10520264	0.789		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_-_10520592	0.763	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_+_45488356	0.760		ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr17_+_45488330	0.742	NM_002204 NM_005501	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr6_-_132314004	0.730	NM_001901	CTGF	connective tissue growth factor
chr12_-_47464143	0.688	NM_015270	ADCY6	adenylate cyclase 6
chr11_+_101485946	0.684	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr2_+_113532685	0.662	NM_173170	IL1F5	interleukin 1 family, member 5 (delta)
chrX_-_148394570	0.652	NM_000202 NM_001166550 NM_006123	IDS	iduronate 2-sulfatase
chr19_-_1966628	0.580	NM_017797	BTBD2	BTB (POZ) domain containing 2
chr1_-_231498081	0.577	NM_014801	PCNXL2	pecanex-like 2 (Drosophila)
chrX_-_107569256	0.554	NM_001847	COL4A6	collagen, type IV, alpha 6
chr5_-_148422799	0.547	NM_024577	SH3TC2	SH3 domain and tetratricopeptide repeats 2
chr3_-_48446405	0.542	NM_001130082	PLXNB1	plexin B1
chrX_+_107569671	0.537	NM_000495 NM_033380	COL4A5	collagen, type IV, alpha 5
chr9_-_83494198	0.530		TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chrX_+_505078	0.517	NM_000451 NM_006883	SHOX	short stature homeobox
chr13_+_113193308	0.517	NM_017905	TMCO3	transmembrane and coiled-coil domains 3
chr17_+_2443983	0.512		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr19_+_53466465	0.473	NM_153608	ZNF114	zinc finger protein 114
chr9_-_106705780	0.464		ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1
chr18_+_54682261	0.454		ZNF532	zinc finger protein 532
chr11_-_122571198	0.453	NM_024769	CLMP	CXADR-like membrane protein
chr13_-_32678142	0.446	NM_052851	STARD13	StAR-related lipid transfer (START) domain containing 13
chr10_-_90601655	0.431	NM_144590	ANKRD22	ankyrin repeat domain 22
chr1_-_167947301	0.426	NM_000655	SELL	selectin L
chr13_+_113193395	0.416		TMCO3	transmembrane and coiled-coil domains 3
chr19_-_57592778	0.409		LOC284373	hypothetical protein LOC284373
chr19_-_9098625	0.404	NM_001001958	OR7G3	olfactory receptor, family 7, subfamily G, member 3
chr20_+_6696744	0.403	NM_001200	BMP2	bone morphogenetic protein 2
chr12_+_84198015	0.394	NM_006982	ALX1	ALX homeobox 1
chr13_+_28131140	0.393	NM_015932	POMP	proteasome maturation protein
chr17_+_2443652	0.393	NM_000430	PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr4_-_86106567	0.392	NM_014991	WDFY3	WD repeat and FYVE domain containing 3
chr17_-_31146660	0.382	NM_001032278 NM_024302	MMP28	matrix metallopeptidase 28
chr4_+_110956085	0.381	NM_018983 NM_032993	GAR1	GAR1 ribonucleoprotein homolog (yeast)
chr6_-_143307976	0.369	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr13_+_46025384	0.365		LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1
chr1_-_202730135	0.360		PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide
chr9_+_35528890	0.357		RUSC2	RUN and SH3 domain containing 2
chrX_-_78509662	0.352	NM_001171581 NM_004867	ITM2A	integral membrane protein 2A
chr9_+_114552871	0.344	NM_001012994	SNX30	sorting nexin family member 30
chr11_-_117628211	0.343	NM_198275	MPZL3	myelin protein zero-like 3
chr12_+_55808696	0.338		LRP1	low density lipoprotein receptor-related protein 1
chr14_+_69415880	0.327	NM_001034852 NM_022137	SMOC1	SPARC related modular calcium binding 1
chr18_+_44319365	0.322	NM_001142397 NM_014772	CTIF	CBP80/20-dependent translation initiation factor
chr11_-_122571046	0.315		CLMP	CXADR-like membrane protein
chr3_-_42282665	0.314	NM_000729	CCK	cholecystokinin
chr17_+_45706786	0.313	NM_153229	TMEM92	transmembrane protein 92
chr3_+_33130451	0.311	NM_006371	CRTAP	cartilage associated protein
chr10_+_104211134	0.308		TMEM180	transmembrane protein 180
chr1_-_150276064	0.303		S100A11	S100 calcium binding protein A11
chr1_-_150276114	0.303	NM_005620	S100A11	S100 calcium binding protein A11
chr6_-_134538762	0.297	NM_001143678	SGK1	serum/glucocorticoid regulated kinase 1
chr8_-_29262240	0.297	NM_057158	DUSP4	dual specificity phosphatase 4
chr19_-_52243721	0.295	NM_017854	TMEM160	transmembrane protein 160
chr11_+_17714070	0.295	NM_001112741 NM_004976	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1
chr1_-_150276091	0.293		S100A11	S100 calcium binding protein A11
chr5_+_35892747	0.293	NM_002185	IL7R	interleukin 7 receptor
chr1_-_223907283	0.291	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr1_-_87152596	0.288	NM_004261 NM_203341	SEP15	15 kDa selenoprotein
chr14_-_63079816	0.285	NM_006246	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr14_-_63079724	0.284		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chrX_-_62891712	0.277		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr16_-_73198498	0.274		GLG1	golgi glycoprotein 1
chr6_-_53638464	0.270	NM_001003760	KLHL31	kelch-like 31 (Drosophila)
chr16_-_73198416	0.269		GLG1	golgi glycoprotein 1
chr12_+_55808514	0.268	NM_002332	LRP1	low density lipoprotein receptor-related protein 1
chr3_+_33130563	0.266		CRTAP	cartilage associated protein
chr6_-_134538526	0.262		SGK1	serum/glucocorticoid regulated kinase 1
chr10_-_103864579	0.262		LDB1	LIM domain binding 1
chr1_-_155336223	0.261	NM_001004341	ETV3L	ets variant 3-like
chr19_+_61798434	0.260	NM_021216	ZNF71	zinc finger protein 71
chr4_-_44145580	0.260	NM_198353	KCTD8	potassium channel tetramerisation domain containing 8
chr2_+_113533155	0.258	NM_012275	IL1F5	interleukin 1 family, member 5 (delta)
chr4_+_151218862	0.255	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr1_-_224993498	0.253	NM_002221	ITPKB	inositol 1,4,5-trisphosphate 3-kinase B
chr11_-_66897584	0.249	NM_013246	CLCF1	cardiotrophin-like cytokine factor 1
chr21_+_38550533	0.247	NM_002243	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr10_+_114700775	0.246		TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr16_-_2848106	0.237	NM_022119	PRSS22	protease, serine, 22
chr14_-_63079492	0.231		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chrX_-_111212659	0.229	NM_012471	TRPC5	transient receptor potential cation channel, subfamily C, member 5
chr13_+_56639331	0.227	NM_198441 NM_001130404 NM_001130405 NM_001130406 NM_001130407	PRR20A PRR20B PRR20C PRR20D PRR20E	proline rich 20A proline rich 20B proline rich 20C proline rich 20D proline rich 20E
chr14_-_63079299	0.227		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr19_+_12996830	0.226		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr17_-_34607257	0.225	NM_000723 NM_199247 NM_199248	CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr8_+_104222052	0.225	NM_001024372 NM_024812	BAALC	brain and acute leukemia, cytoplasmic
chr8_-_145530639	0.224	NM_031309	SCRT1	scratch homolog 1, zinc finger protein (Drosophila)
chr8_-_111056099	0.222	NM_014379	KCNV1	potassium channel, subfamily V, member 1
chr17_+_18796202	0.218	NM_001042450 NM_152351	SLC5A10	solute carrier family 5 (sodium/glucose cotransporter), member 10
chr14_-_93665678	0.215	NM_032036	IFI27L2	interferon, alpha-inducible protein 27-like 2
chr18_-_44189625	0.215		ZBTB7C	zinc finger and BTB domain containing 7C
chr13_+_46025313	0.214		LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1
chr21_+_38550739	0.211	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr9_+_35528628	0.210	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr10_-_103864651	0.208	NM_003893	LDB1	LIM domain binding 1
chr10_+_104211148	0.207	NM_024789	TMEM180	transmembrane protein 180
chr9_+_34169002	0.206	NM_001171201 NM_001171202 NM_001171203 NM_001171204 NM_016525	UBAP1	ubiquitin associated protein 1
chr12_+_107797985	0.204	NM_001917	DAO	D-amino-acid oxidase
chr1_-_20685314	0.200	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_-_73198515	0.194	NM_001145666 NM_001145667 NM_012201	GLG1	golgi glycoprotein 1
chr12_-_47637530	0.194
chr5_+_150020595	0.186	NM_001122853 NM_133371	MYOZ3	myozenin 3
chr6_+_139055244	0.184		FLJ46906	hypothetical LOC441172
chr12_+_14409875	0.182	NM_018179	ATF7IP	activating transcription factor 7 interacting protein
chr13_+_28131279	0.176		POMP	proteasome maturation protein
chr12_+_2774362	0.175	NM_002014	FKBP4	FK506 binding protein 4, 59kDa
chr17_-_71385651	0.174		TRIM47	tripartite motif containing 47
chr3_-_193928038	0.174	NM_004113	FGF12	fibroblast growth factor 12
chr9_+_124836666	0.172	NM_005294	GPR21	G protein-coupled receptor 21
chr12_-_47637396	0.172		ARF3	ADP-ribosylation factor 3
chr13_+_46025482	0.172
chr14_-_93665668	0.171		IFI27L2	interferon, alpha-inducible protein 27-like 2
chr4_+_120029426	0.170	NM_001128933 NM_001128934 NM_133477	SYNPO2	synaptopodin 2
chr13_-_74953873	0.169	NM_014832	TBC1D4	TBC1 domain family, member 4
chr4_+_154345039	0.169	NM_015271	TRIM2	tripartite motif containing 2
chr9_+_77695334	0.168	NM_001190482 NM_006200	PCSK5	proprotein convertase subtilisin/kexin type 5
chr13_+_46025296	0.166	NM_001164211 NM_001164213 NM_015116	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1
chr11_-_76800525	0.165		PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr3_-_48516486	0.165	NM_016479	SHISA5	shisa homolog 5 (Xenopus laevis)
chr19_+_43502591	0.160		KCNK6	potassium channel, subfamily K, member 6
chr10_-_103869923	0.158	NM_001113407	LDB1	LIM domain binding 1
chr9_+_33807168	0.158	NM_017811	UBE2R2	ubiquitin-conjugating enzyme E2R 2
chr12_-_47637518	0.155	NM_001659	ARF3	ADP-ribosylation factor 3
chr16_+_67697622	0.154	NM_138612	HAS3	hyaluronan synthase 3
chr5_-_137117932	0.151		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr5_-_137117936	0.150	NM_006805	HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr5_-_137117873	0.149		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr12_-_47637512	0.148		ARF3	ADP-ribosylation factor 3
chr19_+_12996745	0.146		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr3_+_171558188	0.146		SKIL	SKI-like oncogene
chr9_+_34169023	0.144		UBAP1	ubiquitin associated protein 1
chr7_+_68702252	0.144		AUTS2	autism susceptibility candidate 2
chr10_-_14412813	0.143	NM_018027	FRMD4A	FERM domain containing 4A
chr12_-_47637507	0.142		ARF3	ADP-ribosylation factor 3
chrX_-_152365138	0.141	NM_080701	TREX2	three prime repair exonuclease 2
chr9_+_34169036	0.139		UBAP1	ubiquitin associated protein 1
chr12_-_47637564	0.139		ARF3	ADP-ribosylation factor 3
chr5_-_137117539	0.139		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr5_-_141981083	0.137	NM_001144892	FGF1	fibroblast growth factor 1 (acidic)
chr1_+_156229934	0.134		KIRREL	kin of IRRE like (Drosophila)
chrX_+_24077649	0.134	NM_001178086 NM_001178095 NM_001178084 NM_001178085 NM_003410	ZFX	zinc finger protein, X-linked
chr11_+_9642226	0.132		SWAP70	SWAP switching B-cell complex 70kDa subunit
chr16_+_67724023	0.130		CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)
chr11_-_8789457	0.129	NM_139157	ST5	suppression of tumorigenicity 5
chr6_-_130578110	0.129	NM_152552	SAMD3	sterile alpha motif domain containing 3
chr7_+_68701704	0.129	NM_001127231 NM_001127232 NM_015570	AUTS2	autism susceptibility candidate 2
chr3_-_193609531	0.127	NM_021032	FGF12	fibroblast growth factor 12
chr20_+_10147455	0.126	NM_003081 NM_130811	SNAP25	synaptosomal-associated protein, 25kDa
chr5_-_137117770	0.126		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr11_+_9642182	0.124		SWAP70	SWAP switching B-cell complex 70kDa subunit
chr9_-_106401514	0.123	NM_001004482	OR13C5	olfactory receptor, family 13, subfamily C, member 5
chr15_-_56829104	0.121		ADAM10	ADAM metallopeptidase domain 10
chr4_-_57216816	0.119		HOPX	HOP homeobox
chr1_+_242691295	0.119	NM_001130957 NM_173807	C1orf101	chromosome 1 open reading frame 101
chr8_-_22982435	0.119	NM_003842 NM_147187	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b
chrX_-_62891667	0.118		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr3_-_129852345	0.118		RPN1	ribophorin I
chr9_+_34169058	0.118		UBAP1	ubiquitin associated protein 1
chr3_-_129852400	0.117	NM_002950	RPN1	ribophorin I
chr13_+_56632766	0.117	NM_198441 NM_001130404 NM_001130405 NM_001130406 NM_001130407	PRR20A PRR20B PRR20C PRR20D PRR20E	proline rich 20A proline rich 20B proline rich 20C proline rich 20D proline rich 20E
chr3_+_171558143	0.117	NM_001145098 NM_005414	SKIL	SKI-like oncogene
chr1_-_10964680	0.116	NM_001170754	C1orf127	chromosome 1 open reading frame 127
chr10_+_88708267	0.115	NM_003087	SNCG	synuclein, gamma (breast cancer-specific protein 1)
chr4_+_84676280	0.114		AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr19_+_54621499	0.114	NM_001195256	LOC645971	hypothetical protein LOC645971
chr7_-_99365178	0.112	NM_181538	GJC3	gap junction protein, gamma 3, 30.2kDa
chr16_+_66438348	0.111		NUTF2	nuclear transport factor 2
chr5_-_64100176	0.109		SREK1IP1	SREK1-interacting protein 1
chr4_+_183302105	0.109		ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)
chr19_+_43502301	0.109	NM_004823	KCNK6	potassium channel, subfamily K, member 6
chr19_+_43502380	0.109		KCNK6	potassium channel, subfamily K, member 6
chr17_+_35372751	0.109	NM_178171	GSDMA	gasdermin A
chr5_-_146869613	0.109		DPYSL3	dihydropyrimidinase-like 3
chr14_-_99016833	0.108		SETD3	SET domain containing 3
chr11_-_8788765	0.108	NM_213618	ST5	suppression of tumorigenicity 5
chrX_-_85189194	0.107	NM_000390 NM_001145414	CHM	choroideremia (Rab escort protein 1)
chr12_+_105692466	0.106	NM_018157	RIC8B	resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr11_+_2279812	0.105	NM_139022	TSPAN32	tetraspanin 32
chr11_+_9736408	0.104		LOC283104	hypothetical LOC283104
chr19_+_17972923	0.101	NM_001025604	ARRDC2	arrestin domain containing 2
chr1_-_154737162	0.100		MEF2D	myocyte enhancer factor 2D
chr3_-_188936941	0.100	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr6_+_117044334	0.099	NM_001010892 NM_001161664	RSPH4A	radial spoke head 4 homolog A (Chlamydomonas)
chrX_-_102870207	0.098	NM_001024452 NM_001172285	GLRA4	glycine receptor, alpha 4
chr10_+_70553993	0.097		VPS26A	vacuolar protein sorting 26 homolog A (S. pombe)
chr9_-_83493415	0.097	NM_005077	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr1_-_93030538	0.096	NM_005665	EVI5	ecotropic viral integration site 5
chr5_+_110587546	0.096	NM_001744	CAMK4	calcium/calmodulin-dependent protein kinase IV
chr1_-_20684858	0.093		CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_+_67723988	0.092	NM_032830	CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)
chr3_+_171558215	0.092		SKIL	SKI-like oncogene

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.17	2.36e-04	GO:0009653	anatomical structure morphogenesis
2.53	1.13e-03	GO:0048699	generation of neurons
2.06	2.50e-03	GO:0007399	nervous system development
1.90	3.29e-03	GO:0048583	regulation of response to stimulus
2.39	4.07e-03	GO:0022008	neurogenesis
2.75	6.24e-03	GO:0000902	cell morphogenesis
3.05	7.67e-03	GO:0051094	positive regulation of developmental process
1.69	7.75e-03	GO:0048518	positive regulation of biological process
1.66	1.01e-02	GO:0048731	system development
2.55	1.01e-02	GO:0030182	neuron differentiation
3.09	1.08e-02	GO:0007409	axonogenesis
2.88	1.11e-02	GO:0000904	cell morphogenesis involved in differentiation
1.57	1.15e-02	GO:0007275	multicellular organismal development
2.86	1.28e-02	GO:0048858	cell projection morphogenesis
2.83	1.46e-02	GO:0032990	cell part morphogenesis
2.61	1.58e-02	GO:0032989	cellular component morphogenesis
2.98	1.81e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
1.59	1.88e-02	GO:0048856	anatomical structure development
1.77	1.94e-02	GO:0048869	cellular developmental process
1.52	2.21e-02	GO:0032502	developmental process
2.93	2.33e-02	GO:0048812	neuron projection morphogenesis
2.63	3.01e-02	GO:0048666	neuron development
2.78	3.01e-02	GO:0031175	neuron projection development
13.49	3.26e-02	GO:0030501	positive regulation of bone mineralization
1.75	3.59e-02	GO:0030154	cell differentiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
10.23	2.55e-02	GO:0034704	calcium channel complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.15	3.68e-02	GO:0005261	cation channel activity