Motif ID: NRF1.p2

Z-value: 0.844


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NRF1chr7_+_1290388150.283.0e-01Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_27122307 4.408 NM_024773
 JMJD5
jumonji domain containing 5
chr12_-_52356375 3.993 NM_005176
 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr5_-_271235 3.708 NM_145265
 CCDC127
coiled-coil domain containing 127
chrX_+_84385649 3.698 NM_021998
 ZNF711
zinc finger protein 711
chr12_-_52356123 3.524 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr15_+_40575142 3.439 SNAP23
synaptosomal-associated protein, 23kDa
chr17_-_24302597 3.422 NM_001033561
NM_020889
 PHF12

PHD finger protein 12

chr18_-_17434811 3.349 ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr15_+_40575089 3.318 NM_003825
NM_130798
 SNAP23

synaptosomal-associated protein, 23kDa

chr18_-_17434655 3.277 NM_052911
 ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr3_+_73128667 3.181 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr1_+_229540304 3.095 NM_001010984
NM_032018
 C1orf124

chromosome 1 open reading frame 124

chr2_-_33677798 3.094 NM_015475
 FAM98A
family with sequence similarity 98, member A
chr2_+_254843 3.086 NM_001040649
NM_004300
NM_007099
 ACP1


acid phosphatase 1, soluble


chr19_+_5574088 2.985 SAFB
scaffold attachment factor B
chr10_-_74526596 2.978 P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr2_-_152393209 2.911 NM_001037174
NM_012097
NM_177985
 ARL5A


ADP-ribosylation factor-like 5A


chrX_-_7076146 2.906 NM_001135565
NM_001178135
NM_001178136
NM_012080
 HDHD1



haloacid dehalogenase-like hydrolase domain containing 1



chr11_-_64301807 2.881 NM_001178031
 SF1
splicing factor 1
chr21_+_39674112 2.774 WRB
tryptophan rich basic protein

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 102 entries
enrichment   p-value GO term description
3.07 3.84e-05 GO:0006405 RNA export from nucleus
3.07 2.69e-02 GO:0006413 translational initiation
2.94 1.07e-03 GO:0006406 mRNA export from nucleus
2.89 1.79e-04 GO:0006302 double-strand break repair
2.82 4.23e-05 GO:0051168 nuclear export
2.54 5.59e-05 GO:0051028 mRNA transport
2.51 2.37e-05 GO:0050657 nucleic acid transport
2.51 2.37e-05 GO:0050658 RNA transport
2.51 2.37e-05 GO:0051236 establishment of RNA localization
2.49 2.14e-05 GO:0006403 RNA localization
2.44 2.26e-02 GO:0000956 nuclear-transcribed mRNA catabolic process
2.41 1.99e-05 GO:0006310 DNA recombination
2.35 3.34e-02 GO:0000236 mitotic prometaphase
2.35 3.34e-02 GO:0006402 mRNA catabolic process
2.33 1.35e-07 GO:0000375 RNA splicing, via transesterification reactions
2.32 3.71e-07 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.32 3.71e-07 GO:0000398 nuclear mRNA splicing, via spliceosome
2.29 6.91e-03 GO:0007059 chromosome segregation
2.27 3.07e-04 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.25 1.07e-04 GO:0000226 microtubule cytoskeleton organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 69 entries
enrichment   p-value GO term description
5.42 1.54e-03 GO:0032300 mismatch repair complex
2.82 3.26e-02 GO:0008287 protein serine/threonine phosphatase complex
2.60 4.33e-03 GO:0044450 microtubule organizing center part
2.54 3.67e-02 GO:0005798 Golgi-associated vesicle
2.54 3.67e-02 GO:0034708 methyltransferase complex
2.54 3.67e-02 GO:0035097 histone methyltransferase complex
2.49 4.00e-06 GO:0044455 mitochondrial membrane part
2.49 2.24e-02 GO:0005746 mitochondrial respiratory chain
2.48 4.74e-03 GO:0000777 condensed chromosome kinetochore
2.48 1.03e-02 GO:0000922 spindle pole
2.44 9.03e-04 GO:0000776 kinetochore
2.41 2.61e-02 GO:0070469 respiratory chain
2.32 1.73e-02 GO:0000779 condensed chromosome, centromeric region
2.31 2.55e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.29 2.21e-02 GO:0031461 cullin-RING ubiquitin ligase complex
2.29 2.21e-02 GO:0071013 catalytic step 2 spliceosome
2.27 3.93e-05 GO:0000793 condensed chromosome
2.25 3.86e-04 GO:0016607 nuclear speck
2.17 2.06e-05 GO:0044454 nuclear chromosome part
2.17 2.19e-04 GO:0000775 chromosome, centromeric region

Gene overrepresentation in function category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
5.16 1.23e-03 GO:0030983 mismatched DNA binding
3.27 1.97e-02 GO:0004003 ATP-dependent DNA helicase activity
2.92 6.05e-04 GO:0003697 single-stranded DNA binding
2.82 4.74e-02 GO:0003678 DNA helicase activity
2.82 4.74e-02 GO:0043021 ribonucleoprotein binding
2.20 2.75e-03 GO:0051082 unfolded protein binding
2.16 6.16e-03 GO:0015631 tubulin binding
1.99 5.59e-04 GO:0043566 structure-specific DNA binding
1.97 7.96e-04 GO:0003682 chromatin binding
1.94 6.64e-20 GO:0003723 RNA binding
1.93 2.00e-02 GO:0004518 nuclease activity
1.77 2.40e-03 GO:0016881 acid-amino acid ligase activity
1.76 7.40e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.76 1.08e-02 GO:0019787 small conjugating protein ligase activity
1.71 1.59e-05 GO:0016874 ligase activity
1.61 1.21e-02 GO:0016887 ATPase activity
1.45 9.86e-24 GO:0003676 nucleic acid binding
1.41 7.82e-03 GO:0016462 pyrophosphatase activity
1.40 9.72e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.40 1.20e-02 GO:0016817 hydrolase activity, acting on acid anhydrides