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• Activity deltas table
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Motif ID: NRF1.p2

Z-value: 0.844

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_27122307	4.408	NM_024773	JMJD5	jumonji domain containing 5
chr12_-_52356375	3.993	NM_005176	ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr5_-_271235	3.708	NM_145265	CCDC127	coiled-coil domain containing 127
chrX_+_84385649	3.698	NM_021998	ZNF711	zinc finger protein 711
chr12_-_52356123	3.524		ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr15_+_40575142	3.439		SNAP23	synaptosomal-associated protein, 23kDa
chr17_-_24302597	3.422	NM_001033561 NM_020889	PHF12	PHD finger protein 12
chr18_-_17434811	3.349		ESCO1	establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr15_+_40575089	3.318	NM_003825 NM_130798	SNAP23	synaptosomal-associated protein, 23kDa
chr18_-_17434655	3.277	NM_052911	ESCO1	establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr3_+_73128667	3.181		PPP4R2	protein phosphatase 4, regulatory subunit 2
chr1_+_229540304	3.095	NM_001010984 NM_032018	C1orf124	chromosome 1 open reading frame 124
chr2_-_33677798	3.094	NM_015475	FAM98A	family with sequence similarity 98, member A
chr2_+_254843	3.086	NM_001040649 NM_004300 NM_007099	ACP1	acid phosphatase 1, soluble
chr19_+_5574088	2.985		SAFB	scaffold attachment factor B
chr10_-_74526596	2.978		P4HA1	prolyl 4-hydroxylase, alpha polypeptide I
chr2_-_152393209	2.911	NM_001037174 NM_012097 NM_177985	ARL5A	ADP-ribosylation factor-like 5A
chrX_-_7076146	2.906	NM_001135565 NM_001178135 NM_001178136 NM_012080	HDHD1	haloacid dehalogenase-like hydrolase domain containing 1
chr11_-_64301807	2.881	NM_001178031	SF1	splicing factor 1
chr21_+_39674112	2.774		WRB	tryptophan rich basic protein
chr16_+_48657381	2.756	NM_182922	HEATR3	HEAT repeat containing 3
chr10_-_74526662	2.750	NM_000917 NM_001017962 NM_001142595 NM_001142596	P4HA1	prolyl 4-hydroxylase, alpha polypeptide I
chr9_+_109085337	2.750	NM_002874	RAD23B	RAD23 homolog B (S. cerevisiae)
chr20_+_48781457	2.737	NM_032521	PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)
chr4_-_56107725	2.691	NM_004898	CLOCK	clock homolog (mouse)
chr6_+_30722794	2.655	NM_001109938 NM_001161376 NM_145029	C6orf136	chromosome 6 open reading frame 136
chr16_-_65422365	2.650	NM_001018159 NM_001018160 NM_003905	NAE1	NEDD8 activating enzyme E1 subunit 1
chr8_-_117956226	2.648	NM_006265	RAD21	RAD21 homolog (S. pombe)
chr12_-_52960146	2.639		CBX5	chromobox homolog 5
chr17_-_42924828	2.635		MRPL45P2	mitochondrial ribosomal protein L45 pseudogene 2
chr18_-_17434581	2.611		ESCO1	establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr5_+_162820094	2.551	NM_001142556 NM_001142557 NM_012484 NM_012485	HMMR	hyaluronan-mediated motility receptor (RHAMM)
chr16_-_65422304	2.516		NAE1	NEDD8 activating enzyme E1 subunit 1
chr5_+_138706029	2.500	NM_001033112	PAIP2	poly(A) binding protein interacting protein 2
chr17_+_55325268	2.495		RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr8_+_42368533	2.487		VDAC3	voltage-dependent anion channel 3
chr6_-_153346283	2.466	NM_001142522	FBXO5	F-box protein 5
chr8_+_42368493	2.455	NM_001135694 NM_005662	VDAC3	voltage-dependent anion channel 3
chr20_-_13713509	2.453	NM_016649	ESF1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr1_-_201124848	2.450	NM_002871	RABIF	RAB interacting factor
chr8_-_117956062	2.437		RAD21	RAD21 homolog (S. pombe)
chr17_-_45110339	2.433	NM_001007226 NM_001007227 NM_001007228 NM_001007229 NM_001007230 NM_003563	SPOP	speckle-type POZ protein
chr2_-_106177166	2.424		UXS1	UDP-glucuronate decarboxylase 1
chr22_+_30670592	2.400		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr5_+_61744322	2.390	NM_016338	IPO11	importin 11
chr20_-_35013459	2.366		SAMHD1	SAM domain and HD domain 1
chr5_+_178300799	2.359	NM_001178089 NM_001178090 NM_182594	ZNF454	zinc finger protein 454
chr1_+_165456572	2.347	NM_001198786 NM_002697	POU2F1	POU class 2 homeobox 1
chr1_-_46906569	2.345		ATPAF1	ATP synthase mitochondrial F1 complex assembly factor 1
chr12_+_110935534	2.302	NM_001034025 NM_006817	ERP29	endoplasmic reticulum protein 29
chr17_+_55325224	2.296	NM_003161	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr2_-_118488133	2.288		CCDC93	coiled-coil domain containing 93
chr12_+_123023521	2.281	NM_152437	ZNF664	zinc finger protein 664
chr9_+_109085372	2.257		RAD23B	RAD23 homolog B (S. cerevisiae)
chr8_+_42368540	2.246		VDAC3	voltage-dependent anion channel 3
chr10_-_71663076	2.232	NM_021129	PPA1	pyrophosphatase (inorganic) 1
chr2_+_26110232	2.209	NM_016131	RAB10	RAB10, member RAS oncogene family
chr6_+_33044378	2.174	NM_005104	BRD2	bromodomain containing 2
chr1_+_3763704	2.172	NM_004402	DFFB	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr17_-_55324859	2.165	NM_001193609 NM_001193610 NM_001193611 NM_001193612 NM_001193613 NM_016261	TUBD1	tubulin, delta 1
chr2_+_28828112	2.159	NM_206876 NM_002709	PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme
chr1_+_229181417	2.152	NM_022786	ARV1	ARV1 homolog (S. cerevisiae)
chr9_+_109085386	2.150		RAD23B	RAD23 homolog B (S. cerevisiae)
chr22_+_30670435	2.146	NM_003405	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr5_+_134209628	2.141		C5orf24	chromosome 5 open reading frame 24
chr6_+_41148869	2.140		NFYA	nuclear transcription factor Y, alpha
chr13_+_36291306	2.132	NM_000538	RFXAP	regulatory factor X-associated protein
chr20_-_35013600	2.121	NM_015474	SAMHD1	SAM domain and HD domain 1
chr9_+_114182216	2.121		HSDL2	hydroxysteroid dehydrogenase like 2
chr21_-_39739528	2.106		LCA5L	Leber congenital amaurosis 5-like
chr21_-_32573195	2.103	NM_018944	MIS18A	MIS18 kinetochore protein homolog A (S. pombe)
chr14_-_22634134	2.099		ACIN1	apoptotic chromatin condensation inducer 1
chr3_+_73128629	2.096		PPP4R2	protein phosphatase 4, regulatory subunit 2
chrX_+_146801236	2.081		FMR1	fragile X mental retardation 1
chr1_+_244954153	2.072		SCCPDH	saccharopine dehydrogenase (putative)
chr14_-_22127954	2.067	NM_001344	DAD1	defender against cell death 1
chr15_-_63264494	2.065	NM_006660	CLPX	ClpX caseinolytic peptidase X homolog (E. coli)
chr1_+_227473638	2.056		RAB4A	RAB4A, member RAS oncogene family
chr5_+_10303410	2.052		CCT5	chaperonin containing TCP1, subunit 5 (epsilon)
chr8_+_42368550	2.049		VDAC3	voltage-dependent anion channel 3
chr2_-_37164919	2.038		HEATR5B	HEAT repeat containing 5B
chr14_-_22127902	1.993		DAD1	defender against cell death 1
chr18_-_5286013	1.985	NM_001143823 NM_003409	ZFP161	zinc finger protein 161 homolog (mouse)
chrX_+_146801142	1.977	NM_001185075 NM_001185076 NM_001185081 NM_001185082 NM_002024	FMR1	fragile X mental retardation 1
chr3_+_73128771	1.976	NM_174907	PPP4R2	protein phosphatase 4, regulatory subunit 2
chr12_-_116112495	1.967	NM_015002 NM_033624	FBXO21	F-box protein 21
chr18_+_72663446	1.966		ZNF236	zinc finger protein 236
chr3_+_196870122	1.966		SDHAP2	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr5_-_178983281	1.963	NM_005520	HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)
chr21_-_33065849	1.961	NM_013329 NM_016631	GCFC1	GC-rich sequence DNA-binding factor 1
chr2_+_118562499	1.951	NM_016133	INSIG2	insulin induced gene 2
chr10_+_59698891	1.945	NM_018464	CISD1	CDGSH iron sulfur domain 1
chr19_-_19005326	1.943	NM_001017392 NM_014884	SUGP2	SURP and G patch domain containing 2
chr20_-_35013589	1.941		SAMHD1	SAM domain and HD domain 1
chr20_-_35013523	1.931		SAMHD1	SAM domain and HD domain 1
chr1_-_241484963	1.923		CEP170	centrosomal protein 170kDa
chr9_+_99214000	1.919	NM_014290	TDRD7	tudor domain containing 7
chrX_-_73429101	1.919		MIR374AHG	mir-374a-545 cluster host gene (non-protein coding)
chr17_-_24302450	1.918		PHF12	PHD finger protein 12
chr6_-_41148061	1.916	NM_145063	C6orf130	chromosome 6 open reading frame 130
chr1_-_232681471	1.912	NM_005646	TARBP1	TAR (HIV-1) RNA binding protein 1
chr1_-_3763480	1.910		KIAA0562	KIAA0562
chr16_+_31098959	1.902		FUS	fused in sarcoma
chr20_-_32163743	1.897	NM_003908	EIF2S2	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr7_+_142695584	1.894		CASP2	caspase 2, apoptosis-related cysteine peptidase
chr9_+_114182009	1.893	NM_001195822 NM_032303	HSDL2	hydroxysteroid dehydrogenase like 2
chr16_+_8622974	1.887	NM_024109	METTL22	methyltransferase like 22
chr10_+_86078136	1.874	NM_018999	FAM190B	family with sequence similarity 190, member B
chr2_-_118488041	1.871		CCDC93	coiled-coil domain containing 93
chr10_-_27429325	1.861	NM_014915	ANKRD26	ankyrin repeat domain 26
chr5_+_170747543	1.860		NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr16_+_84204424	1.854	NM_014615	KIAA0182	KIAA0182
chr10_-_124703683	1.852	NM_024942	C10orf88	chromosome 10 open reading frame 88
chr9_+_99214190	1.851		TDRD7	tudor domain containing 7
chr3_+_196870099	1.850		SDHAP2	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr10_+_127502080	1.849	NM_016567 NM_078468 NM_078469	BCCIP	BRCA2 and CDKN1A interacting protein
chr2_-_152393128	1.848		ARL5A	ADP-ribosylation factor-like 5A
chr3_+_10132314	1.839	NM_018462	C3orf10	chromosome 3 open reading frame 10
chr18_-_72663193	1.837		LOC100131655	hypothetical LOC100131655
chr1_+_32251988	1.821	NM_006559	KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1
chr1_+_20081510	1.819
chr3_-_197201497	1.817		SDHAP1 SDHAP2	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr22_+_43938522	1.814		NUP50	nucleoporin 50kDa
chr16_+_88102305	1.811	NM_003119 NM_199367	SPG7	spastic paraplegia 7 (pure and complicated autosomal recessive)
chr3_+_37259684	1.810	NM_001172713 NM_002078	GOLGA4	golgin A4
chr6_-_35996915	1.809	NM_003137	SRPK1	SRSF protein kinase 1
chr7_-_44588344	1.802	NM_182547	TMED4	transmembrane emp24 protein transport domain containing 4
chr6_-_135417647	1.798	NM_001145158 NM_001145207 NM_006620	HBS1L	HBS1-like (S. cerevisiae)
chr5_+_271428	1.791		SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr2_-_69518108	1.790		NFU1	NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr10_+_27833167	1.789	NM_021252	RAB18	RAB18, member RAS oncogene family
chr4_-_658035	1.789	NM_007100	ATP5I	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr22_+_30670543	1.782		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr6_-_118030310	1.781		GOPC	golgi-associated PDZ and coiled-coil motif containing
chr20_-_51644187	1.779		ZNF217	zinc finger protein 217
chr5_+_271447	1.775		SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr12_+_110935644	1.769		ERP29	endoplasmic reticulum protein 29
chr17_+_33706642	1.766		MRPL45	mitochondrial ribosomal protein L45
chr19_-_19005262	1.765		SUGP2	SURP and G patch domain containing 2
chr2_+_71149193	1.762		NAGK	N-acetylglucosamine kinase
chr20_-_10362755	1.758	NM_170784	MKKS	McKusick-Kaufman syndrome
chrX_-_129127361	1.757		AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr6_+_13682628	1.754	NM_001193267 NM_031244 NM_012241	SIRT5	sirtuin 5
chr2_-_118488189	1.747	NM_019044	CCDC93	coiled-coil domain containing 93
chr2_-_37164962	1.739	NM_019024	HEATR5B	HEAT repeat containing 5B
chr16_+_31098962	1.737		FUS	fused in sarcoma
chr14_+_22633728	1.728		C14orf119	chromosome 14 open reading frame 119
chr16_+_48657408	1.726		HEATR3	HEAT repeat containing 3
chr12_+_110935618	1.723		ERP29	endoplasmic reticulum protein 29
chr20_-_32163576	1.721		EIF2S2	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr6_-_35996794	1.716		SRPK1	SRSF protein kinase 1
chr1_-_218329684	1.714		BPNT1	3'(2'), 5'-bisphosphate nucleotidase 1
chr17_-_46692369	1.709	NM_017643	MBTD1	mbt domain containing 1
chr12_+_68039728	1.702	NM_006530	YEATS4	YEATS domain containing 4
chrX_+_13581145	1.702	NM_152634	TCEANC	transcription elongation factor A (SII) N-terminal and central domain containing
chr7_+_142695570	1.697		CASP2	caspase 2, apoptosis-related cysteine peptidase
chr2_+_99124379	1.696	NM_144706	C2orf15	chromosome 2 open reading frame 15
chr14_-_49389246	1.695		NEMF	nuclear export mediator factor
chrX_-_30817329	1.690	NM_152787	TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr8_+_21833111	1.690	NM_015024	XPO7	exportin 7
chr13_-_49554089	1.687		DLEU2	deleted in lymphocytic leukemia 2 (non-protein coding)
chr21_+_39674082	1.686	NM_004627	WRB	tryptophan rich basic protein
chr6_+_53038176	1.684		FBXO9	F-box protein 9
chr7_-_139523187	1.683	NM_030647	JHDM1D	jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr8_-_17315171	1.664		MTMR7	myotubularin related protein 7
chr17_-_44794325	1.656	NM_001145365 NM_014897	ZNF652	zinc finger protein 652
chrX_+_38305634	1.655	NM_004615	TSPAN7	tetraspanin 7
chr5_-_176365971	1.652	NM_016290	UIMC1	ubiquitin interaction motif containing 1
chr16_-_68346299	1.647	NM_014062	NOB1	NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr2_-_101291483	1.645	NM_173647	RNF149	ring finger protein 149
chr5_+_154218389	1.645	NM_004779	CNOT8	CCR4-NOT transcription complex, subunit 8
chr2_+_26110487	1.637		RAB10	RAB10, member RAS oncogene family
chr22_+_22737753	1.637	NM_012295	CABIN1	calcineurin binding protein 1
chr10_-_38186227	1.629	NM_021045	ZNF248	zinc finger protein 248
chrX_-_19443299	1.629	NM_001001671	MAP3K15	mitogen-activated protein kinase kinase kinase 15
chr12_-_52960206	1.625		CBX5	chromobox homolog 5
chr14_-_101623097	1.621		HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr3_+_121797866	1.615		NDUFB4	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr16_-_80761281	1.610	NM_005792	MPHOSPH6	M-phase phosphoprotein 6
chr1_+_16046945	1.602	NM_015001	SPEN	spen homolog, transcriptional regulator (Drosophila)
chr4_+_25931282	1.597		RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr1_+_54184678	1.597		LRRC42	leucine rich repeat containing 42
chr12_+_129922510	1.595	NM_006325	RAN	RAN, member RAS oncogene family
chr10_+_21863272	1.593		MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr6_-_35996867	1.591		SRPK1	SRSF protein kinase 1
chr10_+_21863099	1.591	NM_001195627 NM_001195628 NM_001195630 NM_004641	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_-_158498893	1.586		DCAF8	DDB1 and CUL4 associated factor 8
chr2_-_152393179	1.586		ARL5A	ADP-ribosylation factor-like 5A
chr4_+_25931745	1.583		RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr17_-_74289901	1.583	NM_004762 NM_017456	CYTH1	cytohesin 1
chr2_-_130655616	1.581	NM_001171083 NM_017751 NM_017951	SMPD4	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chr11_+_66643311	1.577	NM_012308	KDM2A	lysine (K)-specific demethylase 2A
chr20_-_391172	1.577	NM_144628	TBC1D20	TBC1 domain family, member 20
chr22_-_30072217	1.575	NM_014323 NM_032050 NM_032051 NM_032052	PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr6_-_118030374	1.566		GOPC	golgi-associated PDZ and coiled-coil motif containing
chr20_-_34835546	1.566	NM_001145316 NM_024918 NM_001145315 NM_001145317 NM_001145318	DSN1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr16_+_29735208	1.564		C16orf53	chromosome 16 open reading frame 53
chr20_+_56989690	1.562	NM_198976	TH1L	TH1-like (Drosophila)
chr2_+_86521781	1.559	NM_018433	KDM3A	lysine (K)-specific demethylase 3A
chr1_+_54184595	1.558	NM_052940	LRRC42	leucine rich repeat containing 42

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.54	5.29e-47	GO:0044260	cellular macromolecule metabolic process
1.36	8.03e-36	GO:0044237	cellular metabolic process
1.43	6.65e-35	GO:0043170	macromolecule metabolic process
1.67	2.15e-29	GO:0090304	nucleic acid metabolic process
1.57	3.06e-27	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28	8.74e-26	GO:0008152	metabolic process
1.30	2.01e-25	GO:0044238	primary metabolic process
1.46	3.40e-21	GO:0034641	cellular nitrogen compound metabolic process
1.44	9.95e-21	GO:0006807	nitrogen compound metabolic process
1.52	2.87e-20	GO:0044267	cellular protein metabolic process
1.60	1.30e-18	GO:0010467	gene expression
1.62	1.32e-18	GO:0016070	RNA metabolic process
1.62	2.96e-17	GO:0006996	organelle organization
2.03	7.46e-16	GO:0051276	chromosome organization
2.00	1.55e-15	GO:0006396	RNA processing
2.04	7.62e-14	GO:0016071	mRNA metabolic process
2.05	2.77e-13	GO:0006974	response to DNA damage stimulus
1.86	2.12e-12	GO:0022403	cell cycle phase
1.93	5.18e-12	GO:0006259	DNA metabolic process
1.36	7.84e-12	GO:0019538	protein metabolic process
2.07	1.25e-11	GO:0000279	M phase
1.38	1.90e-11	GO:0071841	cellular component organization or biogenesis at cellular level
1.12	2.10e-11	GO:0009987	cellular process
2.21	2.22e-11	GO:0006281	DNA repair
1.50	5.16e-11	GO:0034645	cellular macromolecule biosynthetic process
2.10	1.05e-10	GO:0006397	mRNA processing
1.72	1.36e-10	GO:0033554	cellular response to stress
1.48	1.53e-10	GO:0009059	macromolecule biosynthetic process
1.64	2.22e-10	GO:0007049	cell cycle
1.86	5.69e-10	GO:0000278	mitotic cell cycle
1.71	5.95e-10	GO:0022402	cell cycle process
1.36	7.76e-10	GO:0071842	cellular component organization at cellular level
2.17	3.23e-09	GO:0000087	M phase of mitotic cell cycle
2.17	3.23e-09	GO:0008380	RNA splicing
1.86	4.83e-09	GO:0044265	cellular macromolecule catabolic process
1.90	9.06e-09	GO:0006325	chromatin organization
2.02	1.64e-08	GO:0016568	chromatin modification
1.40	2.49e-08	GO:0043412	macromolecule modification
2.11	2.92e-08	GO:0048285	organelle fission
1.76	3.26e-08	GO:0009057	macromolecule catabolic process
2.13	3.34e-08	GO:0000280	nuclear division
2.13	3.34e-08	GO:0007067	mitosis
1.40	1.33e-07	GO:0006464	protein modification process
2.33	1.35e-07	GO:0000375	RNA splicing, via transesterification reactions
1.27	1.66e-07	GO:0071840	cellular component organization or biogenesis
1.63	2.89e-07	GO:0046907	intracellular transport
2.32	3.71e-07	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.32	3.71e-07	GO:0000398	nuclear mRNA splicing, via spliceosome
1.94	9.91e-07	GO:0051301	cell division
1.26	3.62e-06	GO:0016043	cellular component organization
1.31	4.68e-06	GO:0044249	cellular biosynthetic process
1.55	5.58e-06	GO:0045184	establishment of protein localization
1.54	1.38e-05	GO:0015031	protein transport
1.48	1.41e-05	GO:0008104	protein localization
1.93	1.75e-05	GO:0006412	translation
2.41	1.99e-05	GO:0006310	DNA recombination
2.49	2.14e-05	GO:0006403	RNA localization
1.88	2.20e-05	GO:0070647	protein modification by small protein conjugation or removal
2.51	2.37e-05	GO:0050657	nucleic acid transport
2.51	2.37e-05	GO:0050658	RNA transport
2.51	2.37e-05	GO:0051236	establishment of RNA localization
1.42	2.55e-05	GO:0033036	macromolecule localization
3.07	3.84e-05	GO:0006405	RNA export from nucleus
2.82	4.23e-05	GO:0051168	nuclear export
2.54	5.59e-05	GO:0051028	mRNA transport
1.28	6.05e-05	GO:0009058	biosynthetic process
1.94	6.38e-05	GO:0032446	protein modification by small protein conjugation
1.81	7.67e-05	GO:0044419	interspecies interaction between organisms
2.25	1.07e-04	GO:0000226	microtubule cytoskeleton organization
1.83	1.47e-04	GO:0044257	cellular protein catabolic process
1.79	1.64e-04	GO:0030163	protein catabolic process
2.14	1.68e-04	GO:0051169	nuclear transport
2.89	1.79e-04	GO:0006302	double-strand break repair
1.42	1.97e-04	GO:0044248	cellular catabolic process
1.93	2.25e-04	GO:0016567	protein ubiquitination
1.83	2.58e-04	GO:0043632	modification-dependent macromolecule catabolic process
1.81	2.86e-04	GO:0051603	proteolysis involved in cellular protein catabolic process
2.13	2.99e-04	GO:0006913	nucleocytoplasmic transport
2.27	3.07e-04	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.83	3.76e-04	GO:0006511	ubiquitin-dependent protein catabolic process
1.81	4.17e-04	GO:0019941	modification-dependent protein catabolic process
2.94	1.07e-03	GO:0006406	mRNA export from nucleus
1.37	1.45e-03	GO:0051641	cellular localization
1.98	1.71e-03	GO:0006457	protein folding
1.81	3.29e-03	GO:0007017	microtubule-based process
2.29	6.91e-03	GO:0007059	chromosome segregation
1.37	8.11e-03	GO:0051649	establishment of localization in cell
1.56	1.00e-02	GO:0034621	cellular macromolecular complex subunit organization
1.62	1.14e-02	GO:0016032	viral reproduction
1.31	1.61e-02	GO:0009056	catabolic process
2.13	1.62e-02	GO:0045333	cellular respiration
1.66	1.94e-02	GO:0010564	regulation of cell cycle process
2.44	2.26e-02	GO:0000956	nuclear-transcribed mRNA catabolic process
1.71	2.39e-02	GO:0006366	transcription from RNA polymerase II promoter
1.74	2.65e-02	GO:0034660	ncRNA metabolic process
3.07	2.69e-02	GO:0006413	translational initiation
1.72	2.85e-02	GO:0010608	posttranscriptional regulation of gene expression
2.35	3.34e-02	GO:0000236	mitotic prometaphase
2.35	3.34e-02	GO:0006402	mRNA catabolic process
1.84	3.41e-02	GO:0071843	cellular component biogenesis at cellular level
1.61	4.16e-02	GO:0034622	cellular macromolecular complex assembly
2.03	4.42e-02	GO:0048193	Golgi vesicle transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.36	2.74e-74	GO:0043231	intracellular membrane-bounded organelle
1.36	3.28e-74	GO:0043227	membrane-bounded organelle
1.25	1.98e-71	GO:0044424	intracellular part
1.24	2.03e-71	GO:0005622	intracellular
1.31	4.34e-68	GO:0043229	intracellular organelle
1.31	2.43e-67	GO:0043226	organelle
1.50	1.69e-59	GO:0005634	nucleus
1.79	2.69e-42	GO:0044428	nuclear part
1.41	5.15e-41	GO:0044446	intracellular organelle part
1.40	5.37e-39	GO:0044422	organelle part
1.72	2.04e-36	GO:0070013	intracellular organelle lumen
1.69	3.12e-35	GO:0031974	membrane-enclosed lumen
1.69	6.11e-35	GO:0043233	organelle lumen
1.79	2.75e-34	GO:0031981	nuclear lumen
1.89	8.04e-30	GO:0005654	nucleoplasm
1.21	2.92e-22	GO:0005737	cytoplasm
1.42	3.95e-22	GO:0032991	macromolecular complex
2.08	5.08e-17	GO:0005694	chromosome
1.25	5.40e-16	GO:0044444	cytoplasmic part
1.38	3.79e-14	GO:0043234	protein complex
1.84	7.94e-14	GO:0044451	nucleoplasm part
2.07	8.59e-14	GO:0044427	chromosomal part
1.36	1.15e-11	GO:0043228	non-membrane-bounded organelle
1.36	1.15e-11	GO:0043232	intracellular non-membrane-bounded organelle
1.39	1.23e-09	GO:0005829	cytosol
1.49	2.80e-09	GO:0005739	mitochondrion
1.83	3.53e-09	GO:0030529	ribonucleoprotein complex
1.05	3.20e-08	GO:0044464	cell part
1.05	3.38e-08	GO:0005623	cell
1.92	4.34e-07	GO:0005815	microtubule organizing center
1.62	6.66e-07	GO:0044429	mitochondrial part
1.61	1.24e-06	GO:0015630	microtubule cytoskeleton
1.59	1.85e-06	GO:0031967	organelle envelope
2.09	1.89e-06	GO:0005813	centrosome
2.49	4.00e-06	GO:0044455	mitochondrial membrane part
1.69	5.17e-06	GO:0005730	nucleolus
1.56	6.29e-06	GO:0031975	envelope
2.17	2.06e-05	GO:0044454	nuclear chromosome part
2.12	2.75e-05	GO:0005819	spindle
2.27	3.93e-05	GO:0000793	condensed chromosome
2.00	6.34e-05	GO:0000228	nuclear chromosome
2.17	2.19e-04	GO:0000775	chromosome, centromeric region
1.89	2.35e-04	GO:0000785	chromatin
2.25	3.86e-04	GO:0016607	nuclear speck
2.17	5.47e-04	GO:0005681	spliceosomal complex
2.13	7.06e-04	GO:0000151	ubiquitin ligase complex
1.87	7.97e-04	GO:0016604	nuclear body
2.44	9.03e-04	GO:0000776	kinetochore
5.42	1.54e-03	GO:0032300	mismatch repair complex
1.56	3.70e-03	GO:0031966	mitochondrial membrane
2.60	4.33e-03	GO:0044450	microtubule organizing center part
1.54	4.35e-03	GO:0005740	mitochondrial envelope
2.48	4.74e-03	GO:0000777	condensed chromosome kinetochore
1.63	5.35e-03	GO:0019866	organelle inner membrane
1.23	5.97e-03	GO:0031090	organelle membrane
1.66	5.98e-03	GO:0005743	mitochondrial inner membrane
2.48	1.03e-02	GO:0000922	spindle pole
2.32	1.73e-02	GO:0000779	condensed chromosome, centromeric region
2.29	2.21e-02	GO:0031461	cullin-RING ubiquitin ligase complex
2.29	2.21e-02	GO:0071013	catalytic step 2 spliceosome
2.49	2.24e-02	GO:0005746	mitochondrial respiratory chain
2.31	2.55e-02	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
2.41	2.61e-02	GO:0070469	respiratory chain
1.67	2.68e-02	GO:0005759	mitochondrial matrix
1.68	3.05e-02	GO:0005635	nuclear envelope
2.82	3.26e-02	GO:0008287	protein serine/threonine phosphatase complex
2.54	3.67e-02	GO:0005798	Golgi-associated vesicle
2.54	3.67e-02	GO:0034708	methyltransferase complex
2.54	3.67e-02	GO:0035097	histone methyltransferase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.45	9.86e-24	GO:0003676	nucleic acid binding
1.25	1.06e-22	GO:0005515	protein binding
1.94	6.64e-20	GO:0003723	RNA binding
1.12	1.16e-15	GO:0005488	binding
1.38	1.91e-10	GO:0000166	nucleotide binding
1.34	2.12e-08	GO:0003677	DNA binding
1.20	4.59e-08	GO:0003824	catalytic activity
1.71	1.59e-05	GO:0016874	ligase activity
1.35	6.61e-05	GO:0005524	ATP binding
1.34	8.99e-05	GO:0030554	adenyl nucleotide binding
1.34	1.20e-04	GO:0032559	adenyl ribonucleotide binding
1.30	2.06e-04	GO:0035639	purine ribonucleoside triphosphate binding
1.29	3.01e-04	GO:0017076	purine nucleotide binding
1.29	3.52e-04	GO:0032553	ribonucleotide binding
1.29	3.52e-04	GO:0032555	purine ribonucleotide binding
1.99	5.59e-04	GO:0043566	structure-specific DNA binding
2.92	6.05e-04	GO:0003697	single-stranded DNA binding
1.76	7.40e-04	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.97	7.96e-04	GO:0003682	chromatin binding
5.16	1.23e-03	GO:0030983	mismatched DNA binding
1.77	2.40e-03	GO:0016881	acid-amino acid ligase activity
2.20	2.75e-03	GO:0051082	unfolded protein binding
2.16	6.16e-03	GO:0015631	tubulin binding
1.41	7.82e-03	GO:0016462	pyrophosphatase activity
1.40	9.72e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.76	1.08e-02	GO:0019787	small conjugating protein ligase activity
1.40	1.20e-02	GO:0016817	hydrolase activity, acting on acid anhydrides
1.61	1.21e-02	GO:0016887	ATPase activity
1.25	1.81e-02	GO:0016740	transferase activity
3.27	1.97e-02	GO:0004003	ATP-dependent DNA helicase activity
1.93	2.00e-02	GO:0004518	nuclease activity
1.39	2.43e-02	GO:0017111	nucleoside-triphosphatase activity
2.82	4.74e-02	GO:0003678	DNA helicase activity
2.82	4.74e-02	GO:0043021	ribonucleoprotein binding