Motif ID: NKX3-1.p2

Z-value: 1.265


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-1chr8_-_235963460.136.3e-01Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_132000134 3.649 NM_005021
 ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr17_-_61655915 1.932 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr17_-_53847937 1.896 RNF43
ring finger protein 43
chr20_+_30160952 1.621 NM_014742
 TM9SF4
transmembrane 9 superfamily protein member 4
chr5_+_156628929 1.518 NM_014376
 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr4_+_89115892 1.394 SPP1
secreted phosphoprotein 1
chr14_-_105681377 1.383 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr20_+_30161173 1.383 TM9SF4
transmembrane 9 superfamily protein member 4
chr20_+_12937616 1.360 NM_018327
 SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr12_+_130004404 1.342 NM_198827
 GPR133
G protein-coupled receptor 133
chr4_+_89115923 1.308 SPP1
secreted phosphoprotein 1
chr4_+_89115825 1.296 NM_000582
NM_001040058
NM_001040060
 SPP1


secreted phosphoprotein 1


chr4_+_74520796 1.199 NM_001134
 AFP
alpha-fetoprotein
chr4_+_89115862 1.166 SPP1
secreted phosphoprotein 1
chr12_-_14982708 1.104 NM_152321
 ERP27
endoplasmic reticulum protein 27
chr4_-_10295412 1.098 NM_052964
 CLNK
cytokine-dependent hematopoietic cell linker
chr15_+_57691382 1.094 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chrX_-_131401319 1.077 NM_018388
NM_133486
 MBNL3

muscleblind-like 3 (Drosophila)

chr17_-_18890963 1.058 NM_006613
 GRAP
GRB2-related adaptor protein
chr8_-_17787342 1.050 FGL1
fibrinogen-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.81 7.42e-09 GO:0007608 sensory perception of smell
2.79 6.66e-10 GO:0007606 sensory perception of chemical stimulus
1.87 5.56e-04 GO:0007600 sensory perception
1.27 5.38e-05 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.51 5.25e-05 GO:0005576 extracellular region
1.30 5.16e-04 GO:0005886 plasma membrane
1.30 5.29e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
9.22 9.65e-03 GO:0004522 pancreatic ribonuclease activity
7.49 3.95e-02 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters
2.84 2.99e-09 GO:0004984 olfactory receptor activity
2.24 4.29e-10 GO:0004930 G-protein coupled receptor activity
1.85 1.10e-07 GO:0004888 transmembrane receptor activity
1.61 1.52e-05 GO:0004872 receptor activity
1.46 8.16e-04 GO:0004871 signal transducer activity
1.46 8.16e-04 GO:0060089 molecular transducer activity