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Motif ID: NKX3-1.p2

Z-value: 1.265

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_132000134	3.649	NM_005021	ENPP3	ectonucleotide pyrophosphatase/phosphodiesterase 3
chr17_-_61655915	1.932	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr17_-_53847937	1.896		RNF43	ring finger protein 43
chr20_+_30160952	1.621	NM_014742	TM9SF4	transmembrane 9 superfamily protein member 4
chr5_+_156628929	1.518	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr4_+_89115892	1.394		SPP1	secreted phosphoprotein 1
chr14_-_105681377	1.383		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr20_+_30161173	1.383		TM9SF4	transmembrane 9 superfamily protein member 4
chr20_+_12937616	1.360	NM_018327	SPTLC3	serine palmitoyltransferase, long chain base subunit 3
chr12_+_130004404	1.342	NM_198827	GPR133	G protein-coupled receptor 133
chr4_+_89115923	1.308		SPP1	secreted phosphoprotein 1
chr4_+_89115825	1.296	NM_000582 NM_001040058 NM_001040060	SPP1	secreted phosphoprotein 1
chr4_+_74520796	1.199	NM_001134	AFP	alpha-fetoprotein
chr4_+_89115862	1.166		SPP1	secreted phosphoprotein 1
chr12_-_14982708	1.104	NM_152321	ERP27	endoplasmic reticulum protein 27
chr4_-_10295412	1.098	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chr15_+_57691382	1.094		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chrX_-_131401319	1.077	NM_018388 NM_133486	MBNL3	muscleblind-like 3 (Drosophila)
chr17_-_18890963	1.058	NM_006613	GRAP	GRB2-related adaptor protein
chr8_-_17787342	1.050		FGL1	fibrinogen-like 1
chr2_-_21106291	1.003		APOB	apolipoprotein B (including Ag(x) antigen)
chr6_+_30238961	0.989	NM_033229	TRIM15	tripartite motif containing 15
chr4_+_74488947	0.907		ALB	albumin
chr2_-_207291364	0.906	NM_001093730	DYTN	dystrotelin
chr15_+_92700167	0.896	NM_001159644	MCTP2	multiple C2 domains, transmembrane 2
chr6_+_167445284	0.884	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr8_-_16094591	0.872	NM_002445 NM_138715 NM_138716	MSR1	macrophage scavenger receptor 1
chr4_+_74488835	0.854	NM_000477	ALB	albumin
chr9_-_124981125	0.814		STRBP	spermatid perinuclear RNA binding protein
chr8_-_17797127	0.803	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr15_+_57691272	0.799	NM_004751	GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr3_-_198784590	0.776	NM_203315	BDH1	3-hydroxybutyrate dehydrogenase, type 1
chr11_-_30910074	0.758	NM_020869	DCDC5	doublecortin domain containing 5
chr2_+_102294393	0.754	NM_016232	IL18R1 IL1RL1	interleukin 18 receptor 1 interleukin 1 receptor-like 1
chr17_+_50698169	0.727		HLF	hepatic leukemia factor
chr1_+_158975662	0.725	NM_021181	SLAMF7	SLAM family member 7
chr7_+_94377145	0.720	NM_001166161 NM_001166162 NM_001166163	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr6_+_153060722	0.717	NM_025107	MYCT1	myc target 1
chr9_-_35860316	0.712	NM_001004487	OR13J1	olfactory receptor, family 13, subfamily J, member 1
chr14_-_20098929	0.702	NM_001001673 NM_001110356 NM_001110357 NM_001110358 NM_001110359 NM_001110360 NM_001110361	RNASE9	ribonuclease, RNase A family, 9 (non-active)
chr14_+_38772870	0.666	NM_054024	MIA2	melanoma inhibitory activity 2
chrX_-_2892288	0.664	NM_000047	ARSE	arylsulfatase E (chondrodysplasia punctata 1)
chr2_+_102744921	0.661	NM_144632	TMEM182	transmembrane protein 182
chrX_+_107569671	0.636	NM_000495 NM_033380	COL4A5	collagen, type IV, alpha 5
chr2_+_228064531	0.630		AGFG1	ArfGAP with FG repeats 1
chr14_+_38804226	0.616	NM_203354	CTAGE5	CTAGE family, member 5
chr18_+_27210737	0.611	NM_001134453 NM_177986	DSG4	desmoglein 4
chrX_+_57329834	0.604	NM_174912	FAAH2	fatty acid amide hydrolase 2
chr2_+_61225710	0.594	NM_001143960	C2orf74	chromosome 2 open reading frame 74
chr4_-_186934059	0.591	NM_001145673	SORBS2	sorbin and SH3 domain containing 2
chr12_-_78608873	0.585	NM_002583	PAWR	PRKC, apoptosis, WT1, regulator
chr20_-_51633042	0.585	NM_006526	ZNF217	zinc finger protein 217
chr12_-_5925658	0.585	NM_020373	ANO2	anoctamin 2
chr4_-_84254932	0.584	NM_001130715 NM_016619	PLAC8	placenta-specific 8
chr2_-_77602843	0.571	NM_001134745 NM_024993	LRRTM4	leucine rich repeat transmembrane neuronal 4
chr14_+_87541220	0.569	NM_003608	GPR65	G protein-coupled receptor 65
chr14_+_94148466	0.564	NM_001085	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr4_+_152417774	0.564	NM_183375	PRSS48	protease, serine, 48
chr20_-_1298493	0.559		FKBP1A	FK506 binding protein 1A, 12kDa
chr20_+_58146916	0.559		LOC284757	hypothetical protein LOC284757
chr9_-_103237851	0.556	NM_000035	ALDOB	aldolase B, fructose-bisphosphate
chr2_+_115538716	0.554	NM_001178037	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr9_+_95273241	0.552		FAM120A	family with sequence similarity 120A
chr14_-_19553191	0.550	NM_001004712	OR4K14	olfactory receptor, family 4, subfamily K, member 14
chr3_-_156876798	0.545	NM_001130960 NM_001130961	PLCH1	phospholipase C, eta 1
chr10_-_74384485	0.540	NM_032562	PLA2G12B	phospholipase A2, group XIIB
chr17_-_16816113	0.538	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr3_+_99288706	0.537	NM_054106	OR5AC2	olfactory receptor, family 5, subfamily AC, member 2
chr4_+_39084936	0.532		KLB	klotho beta
chr10_-_14856901	0.527	NM_031453	FAM107B	family with sequence similarity 107, member B
chr8_-_59575249	0.524	NM_000780	CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1
chr6_+_144654565	0.517	NM_007124	UTRN	utrophin
chr3_-_42892195	0.515		CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1
chrX_-_130792297	0.511		LOC286467	hypothetical LOC286467
chr2_-_99412694	0.511		REV1	REV1 homolog (S. cerevisiae)
chr12_-_242255	0.507	NM_001190997 NM_016615	SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr11_+_89507465	0.504	NM_005467	NAALAD2	N-acetylated alpha-linked acidic dipeptidase 2
chr6_-_76259976	0.503	NM_015687	FILIP1	filamin A interacting protein 1
chr2_+_64534774	0.502	NM_014181	HSPC159	galectin-related protein
chr9_-_94206648	0.501	NM_014057 NM_033014	OGN	osteoglycin
chr19_-_56612653	0.500	NM_001171156 NM_001171157 NM_001171158 NM_001171159 NM_001171160 NM_001171161 NM_033130	SIGLEC10	sialic acid binding Ig-like lectin 10
chr12_-_101835510	0.496	NM_000277	PAH	phenylalanine hydroxylase
chr4_-_186969041	0.496	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chr4_+_74488910	0.491		ALB	albumin
chr1_-_246869181	0.487	NM_001001827	OR2T35	olfactory receptor, family 2, subfamily T, member 35
chr10_-_7722747	0.484		ITIH5	inter-alpha (globulin) inhibitor H5
chr9_+_106496480	0.484	NM_001004484	OR13D1	olfactory receptor, family 13, subfamily D, member 1
chr10_-_11614279	0.484	NM_001080491	USP6NL	USP6 N-terminal like
chr20_-_31055892	0.484	NM_080675	SUN5	Sad1 and UNC84 domain containing 5
chr4_-_68793928	0.482	NM_182502	TMPRSS11B	transmembrane protease, serine 11B
chr16_+_80626459	0.478		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr11_+_55362802	0.478	NM_001005496	OR5D16	olfactory receptor, family 5, subfamily D, member 16
chr17_+_23818922	0.476
chrX_-_107569256	0.466	NM_001847	COL4A6	collagen, type IV, alpha 6
chr16_+_80626331	0.454	NM_002153	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chrX_+_105823723	0.452	NM_024539	RNF128	ring finger protein 128
chr10_-_69267774	0.450	NM_021800 NM_201262	DNAJC12	DnaJ (Hsp40) homolog, subfamily C, member 12
chr5_-_78317444	0.450	NM_198709	ARSB	arylsulfatase B
chr13_+_23042722	0.448	NM_148957	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr21_-_30460841	0.443	NM_012131	CLDN17	claudin 17
chr2_+_119416214	0.442	NM_006770	MARCO	macrophage receptor with collagenous structure
chr3_+_171183203	0.440		SEC62	SEC62 homolog (S. cerevisiae)
chr3_+_162697289	0.439	NM_001080440	OTOL1	otolin 1 homolog (zebrafish)
chr3_-_147696411	0.436	NM_020359	PLSCR2	phospholipid scramblase 2
chr6_-_48186868	0.432		C6orf138	chromosome 6 open reading frame 138
chr2_-_233349469	0.432	NM_001172416 NM_001172417 NM_002242	KCNJ13	potassium inwardly-rectifying channel, subfamily J, member 13
chr2_-_127817143	0.429	NM_006609	MAP3K2	mitogen-activated protein kinase kinase kinase 2
chr6_+_26473376	0.428	NM_001197247 NM_001197249 NM_007047 NM_001197248	BTN3A2	butyrophilin, subfamily 3, member A2
chr6_-_33016561	0.426	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr4_+_74491272	0.426		ALB	albumin
chr6_-_25982418	0.425	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr6_-_138862273	0.425
chr4_+_74493918	0.423		ALB	albumin
chr1_+_246195157	0.423	NM_001004491	OR2AK2	olfactory receptor, family 2, subfamily AK, member 2
chr11_+_56512922	0.420	NM_001005323	OR5AK2	olfactory receptor, family 5, subfamily AK, member 2
chr4_-_84254873	0.419		PLAC8	placenta-specific 8
chr11_-_13474101	0.418	NM_000315	PTH	parathyroid hormone
chr11_-_55987452	0.415	NM_001004743	OR5M9	olfactory receptor, family 5, subfamily M, member 9
chrX_-_130251068	0.413	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chr6_-_138862271	0.413	NM_001144060	NHSL1	NHS-like 1
chr11_+_55343658	0.410	NM_001001952	OR5D18	olfactory receptor, family 5, subfamily D, member 18
chr10_-_116434364	0.409	NM_001003407 NM_001003408	ABLIM1	actin binding LIM protein 1
chr4_+_71418886	0.408	NM_212557	AMTN	amelotin
chr8_-_86441115	0.406	NM_001164830	CA1	carbonic anhydrase I
chr1_+_81544432	0.406		LPHN2	latrophilin 2
chr2_+_36777406	0.406		VIT	vitrin
chr2_+_234624084	0.405	NM_006944	SPP2	secreted phosphoprotein 2, 24kDa
chr2_-_27215781	0.404	NM_178553	C2orf53	chromosome 2 open reading frame 53
chr6_+_126282078	0.400		NCOA7	nuclear receptor coactivator 7
chr7_-_87180499	0.399	NM_000927	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr12_+_83954229	0.399	NM_001079910 NM_032165	LRRIQ1	leucine-rich repeats and IQ motif containing 1
chr6_+_32003180	0.397	NM_000063 NM_001145903	C2	complement component 2
chr8_-_110689396	0.393		SYBU	syntabulin (syntaxin-interacting)
chr3_-_195553297	0.391	NM_001080513	CPN2	carboxypeptidase N, polypeptide 2
chr6_+_16251260	0.389		MYLIP	myosin regulatory light chain interacting protein
chr4_-_69852090	0.388	NM_024743	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_+_246682699	0.385	NM_001004136	OR2T2	olfactory receptor, family 2, subfamily T, member 2
chr4_-_68511738	0.384	NM_001114387 NM_182606	TMPRSS11A	transmembrane protease, serine 11A
chr20_+_62266217	0.382		MYT1	myelin transcription factor 1
chr3_+_153074118	0.380	NM_033050	SUCNR1	succinate receptor 1
chr1_+_103898844	0.380	NM_020978	AMY2B	amylase, alpha 2B (pancreatic)
chr13_-_97916768	0.376		STK24	serine/threonine kinase 24
chr16_+_80626402	0.375		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr7_+_94953148	0.372	NM_016116 NM_145872	ASB4	ankyrin repeat and SOCS box containing 4
chr16_+_80626456	0.372		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr2_-_131073329	0.366	NM_032545 NM_001079530	CFC1 CFC1B	cripto, FRL-1, cryptic family 1 cripto, FRL-1, cryptic family 1B
chr5_+_121523769	0.361	NM_001195535	LOC728460	hypothetical LOC728460
chr16_-_70763524	0.359	NM_031293	PMFBP1	polyamine modulated factor 1 binding protein 1
chrX_-_32340291	0.353	NM_004011 NM_004012	DMD	dystrophin
chr1_+_205329206	0.353	NM_000716 NM_001017364 NM_001017367	C4BPB	complement component 4 binding protein, beta
chr7_-_93027057	0.353	NM_001164738	CALCR	calcitonin receptor
chr17_+_71975224	0.351	NM_001088	AANAT	aralkylamine N-acetyltransferase
chr10_+_116687904	0.349	NM_139169	TRUB1	TruB pseudouridine (psi) synthase homolog 1 (E. coli)
chr1_+_74473672	0.347	NM_015978	TNNI3K	TNNI3 interacting kinase
chr17_+_46176105	0.346		LUC7L3	LUC7-like 3 (S. cerevisiae)
chr17_+_9670105	0.342	NM_004246	GLP2R	glucagon-like peptide 2 receptor
chr5_+_147672181	0.342	NM_032566	SPINK7	serine peptidase inhibitor, Kazal type 7 (putative)
chrX_-_100920493	0.341		GK	glycerol kinase
chr1_-_68688219	0.336	NM_000329	RPE65	retinal pigment epithelium-specific protein 65kDa
chr2_+_42649105	0.328	NM_020744	MTA3	metastasis associated 1 family, member 3
chr20_+_56919233	0.325		GNAS	GNAS complex locus
chr20_+_29565974	0.324		HM13	histocompatibility (minor) 13
chr10_+_101078784	0.324	NM_020348	CNNM1	cyclin M1
chr20_-_34707971	0.322	NM_032214 NM_175077	SLA2	Src-like-adaptor 2
chr2_+_207512522	0.319	NM_173077	CPO	carboxypeptidase O
chr6_+_49575629	0.318	NM_001010904	GLYATL3	glycine-N-acyltransferase-like 3
chr20_+_43764068	0.317	NM_172005	WFDC13	WAP four-disulfide core domain 13
chr4_+_74498042	0.317		ALB	albumin
chr4_+_74497998	0.314		ALB	albumin
chrX_+_118913827	0.312	NM_001008534 NM_001008535 NM_178813	AKAP14	A kinase (PRKA) anchor protein 14
chr12_-_80676562	0.311		PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr6_+_27400518	0.308	NM_032030	FKSG83	FKSG83
chr17_-_39500512	0.308	NM_152344	LSM12	LSM12 homolog (S. cerevisiae)
chr15_+_22832198	0.305		SNRPN	small nuclear ribonucleoprotein polypeptide N
chr20_-_33580861	0.304	NM_001145350	C20orf173	chromosome 20 open reading frame 173
chr15_-_74963246	0.304	NM_020843	SCAPER	S-phase cyclin A-associated protein in the ER
chr10_+_7785360	0.303		ITIH2	inter-alpha (globulin) inhibitor H2
chr15_-_64108718	0.301
chr17_-_36113502	0.297	NM_019016	KRT24	keratin 24
chr14_+_20429382	0.296	NM_002935	RNASE2 RNASE3	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) ribonuclease, RNase A family, 3
chr14_-_24148658	0.296	NM_033423	GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)
chr11_-_128399218	0.296	NM_014715	ARHGAP32	Rho GTPase activating protein 32
chr8_-_16094518	0.296		MSR1	macrophage scavenger receptor 1
chr2_-_215953818	0.293		FN1	fibronectin 1
chr11_+_55096179	0.293	NM_001004701	OR4C16	olfactory receptor, family 4, subfamily C, member 16
chr1_+_50348052	0.293		ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr14_+_23844269	0.290
chr6_+_53043729	0.289	NM_012347	FBXO9	F-box protein 9
chr19_+_55383249	0.288		MYH14	myosin, heavy chain 14, non-muscle
chr4_+_166519392	0.288	NM_001873	CPE	carboxypeptidase E
chrX_-_23765377	0.287		RPL9	ribosomal protein L9
chr7_-_111216180	0.287		DOCK4	dedicator of cytokinesis 4
chr17_+_50697355	0.286		HLF	hepatic leukemia factor
chr1_-_35143570	0.286	NM_001080418	DLGAP3	discs, large (Drosophila) homolog-associated protein 3
chr14_-_88948486	0.285		FOXN3	forkhead box N3
chr6_+_158654464	0.284		TULP4	tubby like protein 4
chr6_-_28294642	0.281		LOC222699	transducer of ERBB2, 2 pseudogene
chr3_+_188397967	0.281	NM_153708	RTP1	receptor (chemosensory) transporter protein 1
chrX_+_90977115	0.281	NM_001168360 NM_001168361 NM_001168362 NM_001168363	PCDH11X	protocadherin 11 X-linked
chr19_-_14853166	0.280	NM_030901	OR7A17	olfactory receptor, family 7, subfamily A, member 17

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.79	6.66e-10	GO:0007606	sensory perception of chemical stimulus
2.81	7.42e-09	GO:0007608	sensory perception of smell
1.27	5.38e-05	GO:0050896	response to stimulus
1.87	5.56e-04	GO:0007600	sensory perception

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.51	5.25e-05	GO:0005576	extracellular region
1.30	5.16e-04	GO:0005886	plasma membrane
1.30	5.29e-04	GO:0071944	cell periphery

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.24	4.29e-10	GO:0004930	G-protein coupled receptor activity
2.84	2.99e-09	GO:0004984	olfactory receptor activity
1.85	1.10e-07	GO:0004888	transmembrane receptor activity
1.61	1.52e-05	GO:0004872	receptor activity
1.46	8.16e-04	GO:0004871	signal transducer activity
1.46	8.16e-04	GO:0060089	molecular transducer activity
9.22	9.65e-03	GO:0004522	pancreatic ribonuclease activity
7.49	3.95e-02	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters