Motif ID: ARID5B.p2

Z-value: 0.827


Transcription factors associated with ARID5B.p2:

Gene SymbolEntrez IDGene Name
ARID5B 84159 AT rich interactive domain 5B (MRF1-like)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARID5Bchr10_+_63478974-0.476.5e-02Click!


Activity profile for motif ARID5B.p2.

activity profile for motif ARID5B.p2


Sorted Z-values histogram for motif ARID5B.p2

Sorted Z-values for motif ARID5B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARID5B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_121492010 0.759 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr1_-_159604287 0.594 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr5_+_161209969 0.575 NM_001127647
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_+_10101081 0.559 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr17_+_58440629 0.528 NM_025185
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr1_-_156937065 0.495 NM_001005279
OR6K2
olfactory receptor, family 6, subfamily K, member 2
chr3_-_188946168 0.483 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr3_+_68136056 0.483 NM_213609
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr18_+_8708448 0.480


chr15_+_49988882 0.444 TMOD3
tropomodulin 3 (ubiquitous)
chr11_+_57738792 0.424 NM_001004458
OR1S1
olfactory receptor, family 1, subfamily S, member 1
chr17_-_8364942 0.400 MYH10
myosin, heavy chain 10, non-muscle
chr1_-_245902965 0.397 NM_001005487
OR13G1
olfactory receptor, family 13, subfamily G, member 1
chr1_+_58899 0.394 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr6_+_80397690 0.393 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr10_+_118177371 0.390 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr19_-_5735775 0.386 NM_001134316
PRR22
proline rich 22
chr19_+_40541327 0.385 NM_005304
FFAR3
free fatty acid receptor 3
chr2_+_101874765 0.384 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_+_161040343 0.383 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr2_+_119416214 0.373 NM_006770
MARCO
macrophage receptor with collagenous structure
chr10_-_29963906 0.371 NM_021738
SVIL
supervillin
chr1_-_151280201 0.360 NM_006945
SPRR2D
small proline-rich protein 2D
chr12_-_46883341 0.344 NM_001004134
OR10AD1
olfactory receptor, family 10, subfamily AD, member 1
chr5_+_148711419 0.325 GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr15_+_19869841 0.315 NM_001004719
OR4M2
olfactory receptor, family 4, subfamily M, member 2
chr1_-_245120900 0.313 AHCTF1
AT hook containing transcription factor 1
chr12_-_10853940 0.310 NM_023917
TAS2R9
taste receptor, type 2, member 9
chr14_-_80934523 0.303 NM_033104
STON2
stonin 2
chr7_-_104696678 0.303 NM_182691
SRPK2
SRSF protein kinase 2
chr9_+_27514311 0.300 NM_020124
IFNK
interferon, kappa
chr4_-_90197140 0.291 NM_014883
FAM13A
family with sequence similarity 13, member A
chr12_+_45896511 0.286 FAM113B
family with sequence similarity 113, member B
chr17_-_1195096 0.285 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr1_-_151352587 0.283 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr17_-_74244539 0.282


chr11_+_101488380 0.277 NM_001195045
YAP1
Yes-associated protein 1
chr3_+_162697289 0.276 NM_001080440
OTOL1
otolin 1 homolog (zebrafish)
chr12_+_121885246 0.269 HIP1R
huntingtin interacting protein 1 related
chr4_+_53986759 0.268 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr1_+_92405196 0.267 NM_015237
KIAA1107
KIAA1107
chr11_+_55162409 0.265 NM_001004124
OR4P4
olfactory receptor, family 4, subfamily P, member 4
chr11_+_129484540 0.261 APLP2
amyloid beta (A4) precursor-like protein 2
chr9_+_124836666 0.247 NM_005294
GPR21
G protein-coupled receptor 21
chr1_+_86707113 0.238 NM_001285
CLCA1
chloride channel accessory 1
chr1_+_6537924 0.238 NM_138697
NM_177540
TAS1R1

taste receptor, type 1, member 1

chr4_+_1872150 0.237 NM_133334
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr1_-_104040594 0.230 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr7_+_143423073 0.226 NM_001004135
OR2A12
olfactory receptor, family 2, subfamily A, member 12
chr20_+_19863716 0.221 RIN2
Ras and Rab interactor 2
chr3_+_44891101 0.220 NM_003241
TGM4
transglutaminase 4 (prostate)
chr4_+_5577783 0.215 NM_005750
C4orf6
chromosome 4 open reading frame 6
chr12_-_49689255 0.214 SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr3_+_161040439 0.212 SCHIP1
schwannomin interacting protein 1
chr6_-_32247134 0.210 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr12_-_55979413 0.208


chr1_-_197173159 0.207 LOC100131234
familial acute myelogenous leukemia related factor
chr10_-_105835525 0.206 COL17A1
collagen, type XVII, alpha 1
chr20_-_14266200 0.203 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr1_-_195818927 0.203 DENND1B
DENN/MADD domain containing 1B
chr10_+_32896656 0.202 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr21_+_34112456 0.202 ITSN1
intersectin 1 (SH3 domain protein)
chr5_+_137701122 0.200 NM_001135647
FAM53C
family with sequence similarity 53, member C
chrX_-_140614227 0.196 NM_145665
NM_032417
SPANXE
SPANXD
SPANXA2
SPANX family, member E
SPANX family, member D
SPANX family, member A2
chr7_-_22518200 0.194 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr11_+_4859624 0.192 NM_001004759
OR51T1
olfactory receptor, family 51, subfamily T, member 1
chr1_+_234748187 0.191 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr17_-_24265108 0.191 PHF12
PHD finger protein 12
chr8_+_75066117 0.191 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr7_+_77307382 0.188 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr3_-_170864111 0.188 NM_004991
MECOM
MDS1 and EVI1 complex locus
chr4_-_70760381 0.187 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr1_+_169747788 0.186 PRRC2C
proline-rich coiled-coil 2C
chr3_-_150993299 0.185 NM_001144960
C3orf16
chromosome 3 open reading frame 16
chr11_-_106833715 0.185 NM_152434
CWF19L2
CWF19-like 2, cell cycle control (S. pombe)
chr9_+_6318348 0.184 NM_001001874
NM_001001875
NM_033516
TPD52L3


tumor protein D52-like 3


chr7_+_75892187 0.180 NM_001110354
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chrX_-_48976714 0.179 NM_005183
CACNA1F
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr1_+_116727514 0.179 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr4_+_74566325 0.179 NM_001133
AFM
afamin
chr6_+_131508153 0.178 NM_016377
AKAP7
A kinase (PRKA) anchor protein 7
chr7_+_29486010 0.178 NM_001039936
CHN2
chimerin (chimaerin) 2
chr7_+_151284396 0.177 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr1_-_151333624 0.176 NM_001024209
SPRR2E
small proline-rich protein 2E
chr1_-_58920315 0.173


chr15_-_53349775 0.173 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr12_+_27740694 0.172 NM_001029874
REP15
RAB15 effector protein
chr6_-_138862273 0.172


chr4_+_75449720 0.171 NM_001432
EREG
epiregulin
chr2_+_183290912 0.171 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr3_-_79899748 0.168 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr11_+_55297489 0.166 NM_001001967
OR5D13
olfactory receptor, family 5, subfamily D, member 13
chr11_+_55078358 0.166 NM_001001920
OR4C15
olfactory receptor, family 4, subfamily C, member 15
chr12_-_49689295 0.164 NM_001174130
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr19_+_45790911 0.162 NM_003573
LTBP4
latent transforming growth factor beta binding protein 4
chr5_-_145232723 0.162 NM_001080516
GRXCR2
glutaredoxin, cysteine rich 2
chr4_-_64957595 0.160 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr4_-_159313613 0.158 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr2_-_178461710 0.157 NM_001077196
PDE11A
phosphodiesterase 11A
chr12_-_23995109 0.157 SOX5
SRY (sex determining region Y)-box 5
chr14_-_19843918 0.157 TTC5
tetratricopeptide repeat domain 5
chr5_-_98290117 0.156 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr3_+_39484073 0.154 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr12_+_50633430 0.154 NM_020327
ACVR1B
activin A receptor, type IB
chr2_+_101874809 0.154 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr4_+_41395493 0.152 LIMCH1
LIM and calponin homology domains 1
chr21_+_38550533 0.151 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_242205556 0.150 NM_001164356
THAP4
THAP domain containing 4
chr2_+_168383427 0.147 NM_020981
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr11_+_73560088 0.147 PPME1
protein phosphatase methylesterase 1
chr2_-_37397669 0.146 NM_005813
PRKD3
protein kinase D3
chr3_+_57069508 0.146 NM_181727
SPATA12
spermatogenesis associated 12
chr1_+_43063817 0.144 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr3_-_52688768 0.141 NM_018165
NM_181042
PBRM1

polybromo 1

chr17_-_36294962 0.141 NM_019010
KRT20
keratin 20
chrX_+_102471769 0.141 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chrX_+_144136798 0.141 NM_001009614
SPANXN1
SPANX family, member N1
chr18_+_53865455 0.139 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr11_+_6823458 0.139 NM_178168
OR10A5
olfactory receptor, family 10, subfamily A, member 5
chr10_+_124135574 0.139 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr17_+_54587882 0.139 PRR11
proline rich 11
chr12_+_52697160 0.138 HOXC5
HOXC6
homeobox C5
homeobox C6
chr18_+_30810889 0.136 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr11_-_65860450 0.135 NM_004292
RIN1
Ras and Rab interactor 1
chr15_+_69220841 0.135 NM_024817
THSD4
thrombospondin, type I, domain containing 4
chrX_-_129864887 0.135 NM_006375
NM_182314
ENOX2

ecto-NOX disulfide-thiol exchanger 2

chr5_-_94250357 0.134 MCTP1
multiple C2 domains, transmembrane 1
chr11_-_55987452 0.133 NM_001004743
OR5M9
olfactory receptor, family 5, subfamily M, member 9
chr20_-_43767069 0.132 NM_172006
NM_172131
WFDC10B

WAP four-disulfide core domain 10B

chr22_+_16423147 0.132 NM_031481
SLC25A18
solute carrier family 25 (mitochondrial carrier), member 18
chr1_-_203657803 0.132 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr6_-_2785682 0.131 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr12_-_28016182 0.130 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr13_-_109600709 0.129 COL4A1
collagen, type IV, alpha 1
chr12_+_61645361 0.129 RPL14
ribosomal protein L14
chr1_+_149877955 0.129 SNX27
sorting nexin family member 27
chr1_+_47037256 0.129 NM_000779
NM_001099772
CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1

chr20_+_71230 0.128 NM_030931
DEFB126
defensin, beta 126
chr6_+_64344307 0.126 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr2_+_113591940 0.126 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr12_+_49522967 0.126 NM_182559
TMPRSS12
transmembrane (C-terminal) protease, serine 12
chr9_+_34642125 0.126 NM_001142784
IL11RA
interleukin 11 receptor, alpha
chrX_-_105169370 0.126 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr8_-_17599438 0.125 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr14_-_64479198 0.125 NM_002083
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr9_-_116920232 0.124 NM_002160
TNC
tenascin C
chr4_-_151993422 0.122


chr8_-_102029997 0.120 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr10_-_29963847 0.119


chr8_+_92184022 0.117 NM_001129890
LRRC69
leucine rich repeat containing 69
chr2_+_183316574 0.117 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr11_+_119862014 0.116 ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr9_+_124463665 0.116 NM_001005236
OR1L1
olfactory receptor, family 1, subfamily L, member 1
chr13_+_96726197 0.115 MBNL2
muscleblind-like 2 (Drosophila)
chr5_-_125956996 0.114 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr16_-_3783475 0.113 CREBBP
CREB binding protein
chr12_-_118725672 0.112 CIT
citron (rho-interacting, serine/threonine kinase 21)
chr15_-_53996597 0.112 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr1_+_234624266 0.111 NM_145861
EDARADD
EDAR-associated death domain
chr12_-_23628774 0.110 NM_178010
SOX5
SRY (sex determining region Y)-box 5
chrX_+_41433169 0.110 NM_001097579
NM_005300
GPR34

G protein-coupled receptor 34

chr11_-_47467094 0.109 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr19_+_43847049 0.108


chr21_-_35174742 0.108 RUNX1
runt-related transcription factor 1
chr11_-_104274606 0.107 NM_001191016
CASP12
caspase 12 (gene/pseudogene)
chr6_-_138862271 0.106 NM_001144060
NHSL1
NHS-like 1
chr20_-_34921689 0.106 NM_199181
KIAA0889
KIAA0889
chr17_-_7023378 0.106 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chrX_-_10495476 0.106 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr10_+_126140330 0.105 NM_001167880
NM_022126
LHPP

phospholysine phosphohistidine inorganic pyrophosphate phosphatase

chr6_-_30188845 0.105 NM_007028
TRIM31
tripartite motif containing 31
chr11_+_93394025 0.105 NM_001098672
HEPHL1
hephaestin-like 1
chr18_+_18767275 0.104 NM_002894
RBBP8
retinoblastoma binding protein 8
chr2_-_165133239 0.103 GRB14
growth factor receptor-bound protein 14
chr6_-_47361921 0.103 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr2_+_173794692 0.103 ZAK
sterile alpha motif and leucine zipper containing kinase AZK
chr7_-_132371208 0.102 EEF1G
eukaryotic translation elongation factor 1 gamma
chr1_-_151310707 0.102 NM_001017418
SPRR2B
small proline-rich protein 2B
chr2_-_215951161 0.102 FN1
fibronectin 1
chrX_+_139912421 0.102 NM_145664
NM_139019
NM_032461
SPANXB2
SPANXF1
SPANXB1
SPANX family, member B2
SPANX family, member F1
SPANX family, member B1
chr1_-_166373434 0.101 GPR161
G protein-coupled receptor 161
chrX_-_10761729 0.101 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr13_+_52114565 0.101 HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr18_+_27281729 0.100 NM_001944
DSG3
desmoglein 3
chr3_+_142175329 0.100 SLC25A36
solute carrier family 25, member 36
chr1_+_20837001 0.099


chr12_-_48902692 0.099 NM_001113547
LIMA1
LIM domain and actin binding 1
chr1_+_208067890 0.098 NM_014388
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr12_-_11230809 0.097 NM_181429
TAS2R42
taste receptor, type 2, member 42
chr19_-_46080496 0.097 NM_000764
NM_030589
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr5_+_154373452 0.096 NM_001099293
KIF4B
kinesin family member 4B
chr4_+_77829634 0.096 SHROOM3
shroom family member 3
chr6_-_47362102 0.095 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr14_-_106282128 0.095 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_56824672 0.094 DST
dystonin
chr11_+_5466490 0.093 NM_001005163
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr3_+_11242666 0.093 NM_001098211
HRH1
histamine receptor H1
chr4_-_120462705 0.093 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr18_+_59405513 0.093 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr3_-_159872960 0.093 NM_020169
LXN
latexin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.28 5.39e-11 GO:0007606 sensory perception of chemical stimulus
3.24 2.63e-09 GO:0007608 sensory perception of smell
2.43 1.70e-08 GO:0007600 sensory perception
1.39 1.69e-06 GO:0032501 multicellular organismal process
1.34 1.72e-06 GO:0050896 response to stimulus
1.80 4.39e-06 GO:0003008 system process
1.87 2.24e-05 GO:0050877 neurological system process
3.56 1.70e-02 GO:0030162 regulation of proteolysis
4.97 1.72e-02 GO:0010951 negative regulation of endopeptidase activity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.54 5.43e-04 GO:0005576 extracellular region
1.34 6.98e-04 GO:0071944 cell periphery
1.34 9.75e-04 GO:0005886 plasma membrane
15.74 1.49e-02 GO:0005577 fibrinogen complex
1.67 1.89e-02 GO:0044421 extracellular region part

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.33 4.68e-10 GO:0004984 olfactory receptor activity
2.42 2.69e-09 GO:0004930 G-protein coupled receptor activity
1.97 3.88e-07 GO:0004888 transmembrane receptor activity
1.67 1.08e-04 GO:0004872 receptor activity
4.70 2.23e-04 GO:0004867 serine-type endopeptidase inhibitor activity
3.38 1.35e-03 GO:0030414 peptidase inhibitor activity
3.37 2.48e-03 GO:0004866 endopeptidase inhibitor activity
1.51 2.91e-03 GO:0004871 signal transducer activity
1.51 2.91e-03 GO:0060089 molecular transducer activity
3.24 4.36e-03 GO:0061135 endopeptidase regulator activity
2.98 5.15e-03 GO:0061134 peptidase regulator activity
2.41 2.47e-02 GO:0004857 enzyme inhibitor activity