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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: E2F1..5.p2

Z-value: 1.705

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_135544170	6.690		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135544214	6.571		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135544138	5.370	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr10_+_62208256	4.716		CDK1	cyclin-dependent kinase 1
chr10_+_62208094	4.144	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr9_-_98220482	4.094	NM_153695	ZNF367	zinc finger protein 367
chr2_+_173927783	3.707	NM_031942 NM_145810	CDCA7	cell division cycle associated 7
chr20_-_35157744	3.296		RBL1	retinoblastoma-like 1 (p107)
chr11_-_33847507	3.255		LMO2	LIM domain only 2 (rhombotin-like 1)
chr8_-_124477639	3.238		ATAD2	ATPase family, AAA domain containing 2
chr1_-_91260357	3.217		ZNF644	zinc finger protein 644
chr1_-_91260181	3.183	NM_032186 NM_201269	ZNF644	zinc finger protein 644
chr5_-_39110251	3.061	NM_152756	RICTOR	RPTOR independent companion of MTOR, complex 2
chr6_+_88356503	3.059	NM_001197259 NM_012381 NM_181837	ORC3	origin recognition complex, subunit 3
chr1_-_91260131	3.043		ZNF644	zinc finger protein 644
chr1_-_26105230	3.041	NM_203401	STMN1	stathmin 1
chr8_-_121526514	2.980		MRPL13	mitochondrial ribosomal protein L13
chr6_-_27208507	2.978	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr1_-_36008009	2.932	NM_001190481 NM_022111	CLSPN	claspin
chr8_-_124477846	2.928		ATAD2	ATPase family, AAA domain containing 2
chr17_+_54997667	2.865	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chrX_+_24621964	2.837		POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr11_-_33847937	2.830	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr10_+_96295511	2.804	NM_018063	HELLS	helicase, lymphoid-specific
chr8_-_124477869	2.787	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr7_+_50314801	2.770	NM_006060	IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr1_-_23729871	2.675		E2F2	E2F transcription factor 2
chr1_-_26105954	2.673	NM_203399	STMN1	stathmin 1
chr11_-_33847834	2.654		LMO2	LIM domain only 2 (rhombotin-like 1)
chr7_+_120378052	2.644	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr11_-_33848013	2.560		LMO2	LIM domain only 2 (rhombotin-like 1)
chr9_-_98220360	2.558		ZNF367	zinc finger protein 367
chrX_+_130985316	2.535	NM_001042452	MST4	serine/threonine protein kinase MST4
chr1_-_91259601	2.526	NM_016620	ZNF644	zinc finger protein 644
chr2_+_232281491	2.507		PTMA	prothymosin, alpha
chr1_-_24179326	2.486		SRSF10	serine/arginine-rich splicing factor 10
chr6_-_52257500	2.469	NM_002388	MCM3	minichromosome maintenance complex component 3
chr1_-_23730298	2.469	NM_004091	E2F2	E2F transcription factor 2
chr17_+_27288152	2.451	NM_015355	SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr17_+_27288167	2.419		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr6_+_27883877	2.406	NM_003509	HIST1H2AI HIST1H3F	histone cluster 1, H2ai histone cluster 1, H3f
chr2_-_136350404	2.365		MCM6	minichromosome maintenance complex component 6
chr5_-_39110235	2.348		RICTOR	RPTOR independent companion of MTOR, complex 2
chr17_+_27288253	2.344		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr5_+_56505608	2.299		GPBP1	GC-rich promoter binding protein 1
chr3_+_44778212	2.265	NM_020242	KIF15	kinesin family member 15
chr3_+_44778284	2.260		KIF15	kinesin family member 15
chr1_-_26105477	2.259	NM_001145454 NM_005563	STMN1	stathmin 1
chrX_+_24621984	2.249	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr7_+_26207569	2.245	NM_007276	CBX3	chromobox homolog 3
chr4_+_39734902	2.241	NM_018177	N4BP2	NEDD4 binding protein 2
chr4_+_154485224	2.220	NM_032117	MND1	meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr7_+_128861471	2.203	NM_001134336 NM_020704	FAM40B	family with sequence similarity 40, member B
chr7_+_26207854	2.191		CBX3	chromobox homolog 3
chrX_+_130984912	2.119	NM_001042453 NM_016542	MST4	serine/threonine protein kinase MST4
chr6_-_153345786	2.118	NM_012177	FBXO5	F-box protein 5
chr5_+_75414994	2.118	NM_014979	SV2C	synaptic vesicle glycoprotein 2C
chr6_+_27941012	2.117	NM_003511	HIST1H2AI HIST1H2AL	histone cluster 1, H2ai histone cluster 1, H2al
chr7_-_148212292	2.104		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr17_+_26183074	2.103	NM_024857	ATAD5	ATPase family, AAA domain containing 5
chr6_-_27222556	2.099	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chr13_+_33290254	2.096		RFC3	replication factor C (activator 1) 3, 38kDa
chr1_-_23543330	2.095	NM_001102397 NM_001102398 NM_001102399 NM_005826	HNRNPR	heterogeneous nuclear ribonucleoprotein R
chrX_-_131451675	2.094	NM_001170704	MBNL3	muscleblind-like 3 (Drosophila)
chr20_-_35157815	2.092	NM_002895 NM_183404	RBL1	retinoblastoma-like 1 (p107)
chr17_+_27288178	2.089		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr8_-_124477850	2.061		ATAD2	ATPase family, AAA domain containing 2
chr17_+_27288374	2.059
chr22_+_18485057	2.015		RANBP1	RAN binding protein 1
chr7_-_148212310	2.007		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_+_138695144	1.989	NM_016019	LUC7L2	LUC7-like 2 (S. cerevisiae)
chr7_-_158190193	1.973	NM_017760	NCAPG2	non-SMC condensin II complex, subunit G2
chr7_+_93977267	1.969		CASD1	CAS1 domain containing 1
chr2_+_149118791	1.939		EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr2_+_153283381	1.928		ARL6IP6	ADP-ribosylation-like factor 6 interacting protein 6
chr7_+_26207806	1.908	NM_016587	CBX3	chromobox homolog 3
chr11_-_19219000	1.884	NM_024680	E2F8	E2F transcription factor 8
chr2_-_136350472	1.884	NM_005915	MCM6	minichromosome maintenance complex component 6
chr15_-_64436045	1.878	NM_017858	TIPIN	TIMELESS interacting protein
chr1_-_91260174	1.874		ZNF644	zinc finger protein 644
chr2_-_174538675	1.868	NM_001172712 NM_003111	SP3	Sp3 transcription factor
chr2_-_175754366	1.862	NM_001002258 NM_001190329 NM_001689	ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr2_+_153283375	1.861		ARL6IP6	ADP-ribosylation-like factor 6 interacting protein 6
chr1_+_109434896	1.811	NM_020141	TMEM167B	transmembrane protein 167B
chr3_+_38363226	1.806	NM_005108	XYLB	xylulokinase homolog (H. influenzae)
chr1_+_240078167	1.800		EXO1	exonuclease 1
chr7_+_138695209	1.781		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr7_+_103756339	1.766	NM_199000	LHFPL3	lipoma HMGIC fusion partner-like 3
chr1_+_26671548	1.760		HMGN2	high-mobility group nucleosomal binding domain 2
chr1_+_240078094	1.740	NM_130398	EXO1	exonuclease 1
chr5_+_93980108	1.739	NM_032290	ANKRD32	ankyrin repeat domain 32
chr2_+_48395271	1.736	NM_002158	FOXN2	forkhead box N2
chr4_-_39655944	1.734	NM_001100399 NM_001100400	PDS5A	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chrX_-_122694569	1.731	NM_001081550	THOC2	THO complex 2
chr7_+_26207897	1.728		CBX3	chromobox homolog 3
chr7_+_93976927	1.725	NM_022900	CASD1	CAS1 domain containing 1
chr3_-_150286812	1.724	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr2_+_177785667	1.710	NM_194247	HNRNPA3P1 HNRNPA3	heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 heterogeneous nuclear ribonucleoprotein A3
chr7_+_64136078	1.707		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr14_-_54438913	1.703	NM_000161 NM_001024024 NM_001024070 NM_001024071	GCH1	GTP cyclohydrolase 1
chr6_-_27914095	1.698	NM_003510	HIST1H2AK	histone cluster 1, H2ak
chr1_-_47552238	1.686	NM_001048166 NM_003035	STIL	SCL/TAL1 interrupting locus
chr2_+_10180304	1.679	NM_001034	RRM2	ribonucleotide reductase M2
chr5_+_36912656	1.679		NIPBL	Nipped-B homolog (Drosophila)
chr7_-_151764004	1.679	NM_170606	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3
chr2_+_47483750	1.672	NM_000251	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chrX_+_122923236	1.668	NM_001042750 NM_001042751 NM_006603	STAG2	stromal antigen 2
chr2_-_219141199	1.666	NM_020935	USP37	ubiquitin specific peptidase 37
chr8_-_95976599	1.659	NM_057749	CCNE2	cyclin E2
chr15_+_30694982	1.658	NM_014783 NM_199357	ARHGAP11A	Rho GTPase activating protein 11A
chr2_+_177965734	1.636		AGPS	alkylglycerone phosphate synthase
chr3_+_38363299	1.622		XYLB	xylulokinase homolog (H. influenzae)
chr11_-_19219720	1.616		E2F8	E2F transcription factor 8
chr15_+_42507123	1.607		CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr3_+_5138929	1.598	NM_018184	ARL8B	ADP-ribosylation factor-like 8B
chr2_+_149119029	1.593	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr7_-_148212312	1.593		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr3_+_140148765	1.581	NM_001040061	C3orf72	chromosome 3 open reading frame 72
chr4_+_152240182	1.575	NM_001006	RPS3A	ribosomal protein S3A
chr10_+_75580914	1.575	NM_006721	ADK	adenosine kinase
chr8_+_121526823	1.570	NM_022045	MTBP	Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr2_+_47483795	1.570		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr6_-_35764588	1.562		FKBP5	FK506 binding protein 5
chr5_-_79986063	1.558		DHFR	dihydrofolate reductase
chr2_+_47483694	1.553		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr16_-_46052254	1.552		ITFG1	integrin alpha FG-GAP repeat containing 1
chr7_-_148212230	1.534		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr9_+_85785456	1.534	NM_024945	RMI1	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chr6_-_111911106	1.530	NM_002912	REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr1_-_33275071	1.527	NM_013411	AK2	adenylate kinase 2
chr17_-_53439513	1.519		SRSF1	serine/arginine-rich splicing factor 1
chr20_-_39199936	1.518
chr2_+_10180145	1.511	NM_001165931	RRM2	ribonucleotide reductase M2
chr1_-_28113817	1.502	NM_002946	RPA2	replication protein A2, 32kDa
chr1_-_203985780	1.499		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr11_-_62379788	1.497		SNHG1	small nucleolar RNA host gene 1 (non-protein coding)
chr13_-_29938029	1.496	NM_002128	HMGB1	high-mobility group box 1
chr6_+_24883133	1.495	NM_015895	GMNN	geminin, DNA replication inhibitor
chr2_-_174538197	1.480		SP3	Sp3 transcription factor
chr8_+_38208322	1.477	NM_001164232	DDHD2	DDHD domain containing 2
chr2_+_232281470	1.474	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr2_-_70848621	1.470	NM_001185055 NM_001617 NM_017482 NM_017488	ADD2	adducin 2 (beta)
chr7_-_94123413	1.465	NM_001099400 NM_001099401 NM_003919	SGCE	sarcoglycan, epsilon
chr1_-_12599934	1.456	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr1_+_220952681	1.448		BROX	BRO1 domain and CAAX motif containing
chr1_-_203985896	1.443		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr7_-_44854222	1.439	NM_012412 NM_138635 NM_201436 NM_201516 NM_201517	H2AFV	H2A histone family, member V
chrX_-_122694562	1.438		THOC2	THO complex 2
chr1_-_223682324	1.435		LBR	lamin B receptor
chr11_-_85053807	1.433	NM_001039618	CREBZF	CREB/ATF bZIP transcription factor
chrX_-_53466335	1.422	NM_006306	SMC1A	structural maintenance of chromosomes 1A
chr8_+_38208165	1.421	NM_001164234 NM_015214	DDHD2	DDHD domain containing 2
chr22_+_18485068	1.411		RANBP1	RAN binding protein 1
chr5_+_138657317	1.407	NM_001194955 NM_001194956	MATR3	matrin 3
chr16_-_23515104	1.406	NM_005003	NDUFAB1	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr7_+_32734244	1.404		LOC441208	zinc and ring finger 2 pseudogene
chr6_-_17814596	1.400	NM_005124	NUP153	nucleoporin 153kDa
chr4_+_178467973	1.397	NM_018248	NEIL3	nei endonuclease VIII-like 3 (E. coli)
chr9_-_122679387	1.396	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr6_-_27968906	1.394	NM_003514	HIST1H2AM	histone cluster 1, H2am
chr1_+_93317374	1.391	NM_001164391 NM_001164392 NM_001164393 NM_007358	MTF2	metal response element binding transcription factor 2
chr7_+_138695241	1.390		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr5_+_79986049	1.388	NM_002439	MSH3	mutS homolog 3 (E. coli)
chr6_-_160130679	1.386		TCP1	t-complex 1
chr11_+_4072499	1.384	NM_001033	RRM1	ribonucleotide reductase M1
chrX_+_122923279	1.381		STAG2	stromal antigen 2
chr16_+_46052667	1.377	NM_000293 NM_001031835	PHKB	phosphorylase kinase, beta
chr5_+_130627600	1.375	NM_001038702 NM_020240	CDC42SE2	CDC42 small effector 2
chr5_+_138657229	1.368	NM_018834	MATR3	matrin 3
chr7_-_44854188	1.366		H2AFV	H2A histone family, member V
chr17_-_16197433	1.366	NM_181716	CENPV	centromere protein V
chr5_-_36187710	1.361	NM_001007527	LMBRD2	LMBR1 domain containing 2
chr5_+_56505412	1.361	NM_022913	GPBP1	GC-rich promoter binding protein 1
chr3_+_38363292	1.357		XYLB	xylulokinase homolog (H. influenzae)
chr17_+_35697660	1.351	NM_001254	CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr9_-_122679283	1.348		PHF19	PHD finger protein 19
chr2_-_144991556	1.348		ZEB2	zinc finger E-box binding homeobox 2
chr14_+_35365266	1.345	NM_032352	BRMS1L	breast cancer metastasis-suppressor 1-like
chr9_+_70509925	1.344	NM_003558	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr7_+_138695236	1.343		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr6_-_27548438	1.337	NM_007149	ZNF184	zinc finger protein 184
chr11_-_95162333	1.333		FAM76B	family with sequence similarity 76, member B
chr16_-_46052482	1.330	NM_030790	ITFG1	integrin alpha FG-GAP repeat containing 1
chr16_-_46052596	1.324		ITFG1	integrin alpha FG-GAP repeat containing 1
chr16_-_48960186	1.322	NM_001173984 NM_013263	BRD7	bromodomain containing 7
chr7_+_64975778	1.315		VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr15_+_42506870	1.315	NM_016396	CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_-_24179419	1.309	NM_001191005 NM_001191006 NM_001191007 NM_001191009 NM_006625 NM_054016	SRSF10	serine/arginine-rich splicing factor 10
chr11_-_95162288	1.306		FAM76B	family with sequence similarity 76, member B
chr7_-_151763857	1.305		MLL3	myeloid/lymphoid or mixed-lineage leukemia 3
chr21_-_32026276	1.297	NM_001145444 NM_001145445 NM_020706	SCAF4	SR-related CTD-associated factor 4
chr5_-_79986104	1.292		DHFR	dihydrofolate reductase
chr6_-_35764655	1.290	NM_001145776 NM_001145777 NM_004117	FKBP5	FK506 binding protein 5
chr2_+_85619802	1.288		MAT2A	methionine adenosyltransferase II, alpha
chr1_-_54291378	1.286		TMEM59	transmembrane protein 59
chr12_-_109665019	1.286		PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme
chrX_+_118592568	1.285		UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr4_-_175986952	1.282	NM_001042543 NM_006529	GLRA3	glycine receptor, alpha 3
chr1_+_220952518	1.273	NM_144695	BROX	BRO1 domain and CAAX motif containing
chr1_-_227761038	1.273	NM_012089	ABCB10	ATP-binding cassette, sub-family B (MDR/TAP), member 10

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.99	3.68e-34	GO:0090304	nucleic acid metabolic process
1.84	3.87e-33	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.55	4.80e-33	GO:0007049	cell cycle
1.59	6.62e-31	GO:0044260	cellular macromolecule metabolic process
2.82	1.94e-28	GO:0022403	cell cycle phase
2.61	3.24e-27	GO:0022402	cell cycle process
1.68	2.97e-26	GO:0034641	cellular nitrogen compound metabolic process
1.65	2.70e-25	GO:0006807	nitrogen compound metabolic process
2.84	3.10e-24	GO:0000278	mitotic cell cycle
2.76	7.53e-24	GO:0051276	chromosome organization
1.46	1.01e-22	GO:0043170	macromolecule metabolic process
1.37	1.85e-20	GO:0044237	cellular metabolic process
2.67	2.06e-20	GO:0006259	DNA metabolic process
1.34	1.37e-18	GO:0044238	primary metabolic process
3.21	3.62e-17	GO:0051325	interphase
3.18	2.09e-16	GO:0051329	interphase of mitotic cell cycle
1.79	2.12e-16	GO:0016070	RNA metabolic process
3.84	4.89e-16	GO:0006260	DNA replication
2.51	3.88e-15	GO:0016071	mRNA metabolic process
2.53	7.56e-15	GO:0006974	response to DNA damage stimulus
1.78	1.33e-14	GO:0006996	organelle organization
1.27	9.15e-14	GO:0008152	metabolic process
1.74	9.15e-14	GO:0034645	cellular macromolecule biosynthetic process
2.84	2.02e-13	GO:0006281	DNA repair
2.52	2.36e-13	GO:0006325	chromatin organization
1.72	3.57e-13	GO:0009059	macromolecule biosynthetic process
2.29	4.29e-13	GO:0051726	regulation of cell cycle
2.57	5.11e-13	GO:0000279	M phase
1.68	5.87e-13	GO:0010467	gene expression
3.84	3.64e-12	GO:0000082	G1/S transition of mitotic cell cycle
1.55	1.19e-11	GO:0044249	cellular biosynthetic process
4.08	3.50e-11	GO:0071824	protein-DNA complex subunit organization
1.14	4.29e-11	GO:0009987	cellular process
4.09	7.73e-11	GO:0051320	S phase
2.15	1.15e-10	GO:0006396	RNA processing
4.09	1.71e-10	GO:0065004	protein-DNA complex assembly
2.51	1.87e-10	GO:0006397	mRNA processing
4.05	2.36e-10	GO:0000084	S phase of mitotic cell cycle
1.50	2.87e-10	GO:0009058	biosynthetic process
3.51	2.94e-10	GO:0071103	DNA conformation change
2.74	3.64e-10	GO:0000280	nuclear division
2.74	3.64e-10	GO:0007067	mitosis
1.41	4.16e-10	GO:0071840	cellular component organization or biogenesis
4.86	7.53e-10	GO:0006261	DNA-dependent DNA replication
2.56	7.91e-10	GO:0010564	regulation of cell cycle process
1.41	9.27e-10	GO:0016043	cellular component organization
3.55	1.39e-09	GO:0006333	chromatin assembly or disassembly
2.66	1.42e-09	GO:0000087	M phase of mitotic cell cycle
4.01	1.58e-09	GO:0034728	nucleosome organization
2.65	1.67e-09	GO:0048285	organelle fission
4.09	1.84e-09	GO:0031497	chromatin assembly
1.46	1.87e-09	GO:0071841	cellular component organization or biogenesis at cellular level
3.61	2.99e-09	GO:0006323	DNA packaging
1.91	7.64e-09	GO:0033554	cellular response to stress
1.98	1.73e-08	GO:0065003	macromolecular complex assembly
3.42	1.83e-08	GO:0006310	DNA recombination
1.45	2.03e-08	GO:0071842	cellular component organization at cellular level
2.39	3.27e-08	GO:0034622	cellular macromolecular complex assembly
1.71	3.46e-08	GO:0044085	cellular component biogenesis
2.53	4.57e-08	GO:0008380	RNA splicing
3.92	7.00e-08	GO:0006334	nucleosome assembly
1.85	8.64e-08	GO:0043933	macromolecular complex subunit organization
2.80	1.50e-07	GO:0000075	cell cycle checkpoint
2.75	1.80e-07	GO:0071156	regulation of cell cycle arrest
2.12	2.45e-07	GO:0034621	cellular macromolecular complex subunit organization
2.33	3.63e-07	GO:0051301	cell division
1.72	4.18e-07	GO:0022607	cellular component assembly
1.36	4.81e-07	GO:0060255	regulation of macromolecule metabolic process
2.29	6.24e-07	GO:0016568	chromatin modification
1.43	6.37e-07	GO:2000112	regulation of cellular macromolecule biosynthetic process
6.51	1.69e-06	GO:0006271	DNA strand elongation involved in DNA replication
1.33	1.70e-06	GO:0031323	regulation of cellular metabolic process
1.40	2.20e-06	GO:0031326	regulation of cellular biosynthetic process
2.72	2.52e-06	GO:0000375	RNA splicing, via transesterification reactions
2.73	3.60e-06	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.73	3.60e-06	GO:0000398	nuclear mRNA splicing, via spliceosome
1.38	4.43e-06	GO:0009889	regulation of biosynthetic process
1.40	5.45e-06	GO:0010556	regulation of macromolecule biosynthetic process
6.07	5.99e-06	GO:0022616	DNA strand elongation
3.39	7.08e-06	GO:0007059	chromosome segregation
1.72	8.61e-06	GO:0010605	negative regulation of macromolecule metabolic process
1.32	8.66e-06	GO:0080090	regulation of primary metabolic process
3.19	9.93e-06	GO:0050657	nucleic acid transport
3.19	9.93e-06	GO:0050658	RNA transport
3.19	9.93e-06	GO:0051236	establishment of RNA localization
1.39	1.05e-05	GO:0010468	regulation of gene expression
1.29	1.24e-05	GO:0019222	regulation of metabolic process
1.78	1.60e-05	GO:0071844	cellular component assembly at cellular level
3.26	1.83e-05	GO:0051028	mRNA transport
4.52	2.06e-05	GO:0051053	negative regulation of DNA metabolic process
3.09	2.36e-05	GO:0006403	RNA localization
1.66	3.39e-05	GO:0009892	negative regulation of metabolic process
7.42	5.34e-05	GO:0007062	sister chromatid cohesion
1.84	5.93e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.35	6.70e-05	GO:0051171	regulation of nitrogen compound metabolic process
9.11	7.60e-05	GO:0071897	DNA biosynthetic process
3.58	9.77e-05	GO:0000216	M/G1 transition of mitotic cell cycle
1.68	1.02e-04	GO:0006351	transcription, DNA-dependent
2.84	1.21e-04	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
3.66	1.25e-04	GO:0006338	chromatin remodeling
6.34	1.35e-04	GO:0090329	regulation of DNA-dependent DNA replication
3.86	1.92e-04	GO:0031124	mRNA 3'-end processing
1.65	2.05e-04	GO:0031324	negative regulation of cellular metabolic process
6.68	2.42e-04	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
6.68	2.42e-04	GO:2000104	negative regulation of DNA-dependent DNA replication
3.06	2.48e-04	GO:0006401	RNA catabolic process
4.79	3.18e-04	GO:0008156	negative regulation of DNA replication
1.76	4.59e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
2.16	4.71e-04	GO:0006366	transcription from RNA polymerase II promoter
1.33	5.49e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59	6.29e-04	GO:0032774	RNA biosynthetic process
1.72	7.43e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.36	8.08e-04	GO:0051252	regulation of RNA metabolic process
6.07	8.69e-04	GO:0006270	DNA-dependent DNA replication initiation
3.40	1.00e-03	GO:0031123	RNA 3'-end processing
1.82	1.07e-03	GO:0044265	cellular macromolecule catabolic process
4.34	1.48e-03	GO:0006369	termination of RNA polymerase II transcription
1.74	1.49e-03	GO:0009057	macromolecule catabolic process
3.22	1.51e-03	GO:0006402	mRNA catabolic process
3.31	1.62e-03	GO:0000956	nuclear-transcribed mRNA catabolic process
3.71	1.68e-03	GO:0006406	mRNA export from nucleus
1.33	1.77e-03	GO:0044267	cellular protein metabolic process
1.69	1.85e-03	GO:0009890	negative regulation of biosynthetic process
9.45	2.02e-03	GO:0002566	somatic diversification of immune receptors via somatic mutation
9.45	2.02e-03	GO:0016446	somatic hypermutation of immunoglobulin genes
5.21	2.06e-03	GO:0043044	ATP-dependent chromatin remodeling
5.57	2.64e-03	GO:0031055	chromatin remodeling at centromere
6.07	3.04e-03	GO:0006298	mismatch repair
1.72	3.42e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35	4.01e-03	GO:0048523	negative regulation of cellular process
1.32	4.91e-03	GO:0048519	negative regulation of biological process
1.70	5.59e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.33	8.39e-03	GO:0006355	regulation of transcription, DNA-dependent
3.31	1.02e-02	GO:0006405	RNA export from nucleus
4.27	1.04e-02	GO:0051318	G1 phase
2.41	1.20e-02	GO:0000226	microtubule cytoskeleton organization
1.52	1.29e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.67	1.70e-02	GO:0007126	meiosis
2.67	1.70e-02	GO:0051327	M phase of meiotic cell cycle
5.75	1.88e-02	GO:0032201	telomere maintenance via semi-conservative replication
2.29	1.92e-02	GO:0006913	nucleocytoplasmic transport
9.11	1.93e-02	GO:0000731	DNA synthesis involved in DNA repair
9.11	1.93e-02	GO:0007064	mitotic sister chromatid cohesion
1.14	1.95e-02	GO:0050794	regulation of cellular process
2.96	1.96e-02	GO:0051168	nuclear export
2.65	2.01e-02	GO:0051321	meiotic cell cycle
3.78	2.28e-02	GO:0000819	sister chromatid segregation
4.29	2.33e-02	GO:0000080	G1 phase of mitotic cell cycle
2.26	2.47e-02	GO:0051169	nuclear transport
5.47	3.16e-02	GO:0000722	telomere maintenance via recombination
4.45	3.64e-02	GO:0007131	reciprocal meiotic recombination
4.86	3.67e-02	GO:0002200	somatic diversification of immune receptors
4.86	3.67e-02	GO:0043486	histone exchange
6.07	3.76e-02	GO:0006297	nucleotide-excision repair, DNA gap filling
3.29	3.77e-02	GO:0000079	regulation of cyclin-dependent protein kinase activity
2.38	4.72e-02	GO:0051052	regulation of DNA metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.64	1.62e-56	GO:0005634	nucleus
1.36	3.01e-54	GO:0043226	organelle
1.36	6.54e-54	GO:0043229	intracellular organelle
1.40	2.27e-52	GO:0043227	membrane-bounded organelle
1.40	7.33e-52	GO:0043231	intracellular membrane-bounded organelle
2.16	9.47e-48	GO:0044428	nuclear part
1.26	4.32e-46	GO:0044424	intracellular part
1.25	2.44e-44	GO:0005622	intracellular
2.19	2.25e-41	GO:0031981	nuclear lumen
2.01	4.88e-39	GO:0070013	intracellular organelle lumen
1.99	6.48e-38	GO:0043233	organelle lumen
1.97	1.49e-37	GO:0031974	membrane-enclosed lumen
2.36	1.09e-36	GO:0005654	nucleoplasm
1.51	4.42e-36	GO:0044446	intracellular organelle part
1.50	1.69e-35	GO:0044422	organelle part
3.04	7.35e-30	GO:0005694	chromosome
3.07	1.83e-25	GO:0044427	chromosomal part
1.54	1.48e-20	GO:0032991	macromolecular complex
1.58	3.03e-17	GO:0043228	non-membrane-bounded organelle
1.58	3.03e-17	GO:0043232	intracellular non-membrane-bounded organelle
2.29	3.54e-17	GO:0044451	nucleoplasm part
3.44	3.78e-17	GO:0000785	chromatin
2.95	4.66e-10	GO:0000228	nuclear chromosome
1.06	8.41e-10	GO:0044464	cell part
2.87	8.64e-10	GO:0016604	nuclear body
1.06	8.79e-10	GO:0005623	cell
3.14	1.67e-09	GO:0044454	nuclear chromosome part
1.41	2.51e-09	GO:0043234	protein complex
2.13	4.27e-09	GO:0030529	ribonucleoprotein complex
3.76	3.95e-08	GO:0032993	protein-DNA complex
10.79	7.65e-06	GO:0035098	ESC/E(Z) complex
2.80	1.77e-05	GO:0000775	chromosome, centromeric region
1.14	2.32e-05	GO:0005737	cytoplasm
1.88	3.53e-05	GO:0005730	nucleolus
3.41	4.70e-05	GO:0000790	nuclear chromatin
3.72	1.31e-04	GO:0000786	nucleosome
4.60	2.68e-04	GO:0005657	replication fork
6.39	2.82e-04	GO:0031519	PcG protein complex
8.10	3.36e-04	GO:0032300	mismatch repair complex
2.65	4.11e-04	GO:0005681	spliceosomal complex
3.23	4.45e-04	GO:0071013	catalytic step 2 spliceosome
2.52	1.24e-03	GO:0000793	condensed chromosome
3.60	1.85e-03	GO:0034708	methyltransferase complex
3.60	1.85e-03	GO:0035097	histone methyltransferase complex
2.59	2.32e-03	GO:0016607	nuclear speck
3.47	3.12e-03	GO:0016605	PML body
1.60	3.86e-03	GO:0015630	microtubule cytoskeleton
2.02	6.30e-03	GO:0005635	nuclear envelope
4.31	8.99e-03	GO:0000932	cytoplasmic mRNA processing body
5.72	1.13e-02	GO:0030894	replisome
5.72	1.13e-02	GO:0043601	nuclear replisome
2.15	1.24e-02	GO:0005819	spindle
4.97	1.39e-02	GO:0043596	nuclear replication fork
3.59	1.52e-02	GO:0000792	heterochromatin
5.40	1.89e-02	GO:0030530	heterogeneous nuclear ribonucleoprotein complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.62	4.29e-25	GO:0003676	nucleic acid binding
1.29	9.85e-19	GO:0005515	protein binding
1.62	5.11e-16	GO:0003677	DNA binding
1.13	3.19e-13	GO:0005488	binding
1.94	1.19e-10	GO:0003723	RNA binding
1.47	6.23e-09	GO:0000166	nucleotide binding
4.69	1.54e-07	GO:0003697	single-stranded DNA binding
2.69	2.17e-06	GO:0043566	structure-specific DNA binding
2.66	3.03e-06	GO:0003682	chromatin binding
3.61	3.34e-04	GO:0008094	DNA-dependent ATPase activity
5.03	8.23e-04	GO:0034061	DNA polymerase activity
3.15	1.75e-03	GO:0003729	mRNA binding
5.14	1.77e-03	GO:0003887	DNA-directed DNA polymerase activity
6.94	2.58e-03	GO:0030983	mismatched DNA binding
2.52	2.62e-03	GO:0003690	double-stranded DNA binding
1.32	1.29e-02	GO:0017076	purine nucleotide binding
1.32	1.32e-02	GO:0032553	ribonucleotide binding
1.32	1.32e-02	GO:0032555	purine ribonucleotide binding
1.35	1.94e-02	GO:0032559	adenyl ribonucleotide binding
1.31	2.13e-02	GO:0035639	purine ribonucleoside triphosphate binding
1.44	2.47e-02	GO:0030528	transcription regulator activity
1.34	2.60e-02	GO:0030554	adenyl nucleotide binding
1.35	2.78e-02	GO:0005524	ATP binding
5.40	2.79e-02	GO:0016538	cyclin-dependent protein kinase regulator activity
12.14	3.02e-02	GO:0032138	single base insertion or deletion binding