Motif ID: NFE2L2.p2

Z-value: 2.189


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L2chr2_-_1778367730.421.0e-01Click!


Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_34206070 2.984 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr12_+_54361596 2.221 NM_152637
METTL7B
methyltransferase like 7B
chr22_+_21484240 2.150


chr12_+_54361685 2.003 METTL7B
methyltransferase like 7B
chrX_-_154216929 1.988 NM_001289
CLIC2
chloride intracellular channel 2
chr1_-_156923111 1.857 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_+_37926943 1.841 EPDR1
ependymin related protein 1 (zebrafish)
chrX_-_100527799 1.817 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr18_+_148586 1.672 USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr3_+_142569988 1.575 ZBTB38
zinc finger and BTB domain containing 38
chr6_+_150112549 1.458 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr6_+_150112537 1.443 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr4_+_76700281 1.417 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr16_+_29984544 1.401 NM_184041
ALDOA
aldolase A, fructose-bisphosphate
chr17_-_25642962 1.390 NM_000386
BLMH
bleomycin hydrolase
chr16_+_29984621 1.376 ALDOA
aldolase A, fructose-bisphosphate
chr22_+_21065134 1.372 LOC100290481
immunoglobulin lambda light chain-like
chr12_+_100512877 1.336 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr16_+_30326864 1.330 ZNF771
zinc finger protein 771
chr16_+_29984611 1.317 ALDOA
aldolase A, fructose-bisphosphate
chr6_+_150112511 1.271 NM_005389
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr3_-_121884091 1.224 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr22_+_21079355 1.205


chr18_+_148480 1.200 NM_001037334
NM_005151
USP14

ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

chr8_-_42742729 1.198 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr6_+_32229278 1.185 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr16_+_51690564 1.174 CHD9
chromodomain helicase DNA binding protein 9
chr3_-_121883647 1.165 HGD
homogentisate 1,2-dioxygenase
chr20_-_29524476 1.144 NM_001037500
DEFB124
defensin, beta 124
chr20_+_41621079 1.138 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chrX_-_70243362 1.135 NM_001025265
CXorf65
chromosome X open reading frame 65
chr1_+_221955876 1.134 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr15_+_57691382 1.133 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr4_+_22608252 1.129


chr22_+_21370394 1.102 IGL@
immunoglobulin lambda locus
chr1_-_24307514 1.094 MYOM3
myomesin family, member 3
chr22_+_21407066 1.067


chr16_+_29984591 1.062 ALDOA
aldolase A, fructose-bisphosphate
chrX_+_9391314 1.041 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr8_-_30704762 1.038 GSR
glutathione reductase
chr22_+_21340757 1.034


chr22_+_21094094 1.029


chr5_+_61750467 0.998 NM_001134779
IPO11
importin 11
chr11_-_14498462 0.996 NM_001143937
NM_002786
PSMA1

proteasome (prosome, macropain) subunit, alpha type, 1

chr6_+_84626146 0.975 CYB5R4
cytochrome b5 reductase 4
chr6_+_32229599 0.973 NM_005155
PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr9_+_70584739 0.972 NM_138333
FAM122A
family with sequence similarity 122A
chr22_+_21393107 0.959 IGLJ3
immunoglobulin lambda joining 3
chr22_+_21053972 0.946


chr17_-_70401299 0.944 NM_178128
FADS6
fatty acid desaturase domain family, member 6
chr11_-_14498443 0.935 PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr6_-_28429950 0.935 NM_145909
ZNF323
zinc finger protein 323
chr17_+_71109734 0.931 MYO15B
myosin XVB pseudogene
chr5_-_95184221 0.916 NM_001118890
NM_002064
GLRX

glutaredoxin (thioltransferase)

chr20_-_581844 0.913 NM_080725
SRXN1
sulfiredoxin 1
chr22_+_43451600 0.904 PRR5
proline rich 5 (renal)
chr17_+_27795635 0.883 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr8_-_38505331 0.883 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr6_-_35996794 0.865 SRPK1
SRSF protein kinase 1
chr6_-_31812049 0.860 CLIC1
chloride intracellular channel 1
chrX_-_109570113 0.855 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr22_+_21042091 0.851 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr2_+_87536174 0.847 NCRNA00152
non-protein coding RNA 152
chr4_-_84152985 0.842 NM_001115007
LIN54
lin-54 homolog (C. elegans)
chr22_+_43451351 0.841 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr7_-_150352484 0.818 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr17_+_27795633 0.816 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr7_+_139175420 0.814 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr16_+_88696172 0.813 FAM157C
family with sequence similarity 157, member C
chr10_+_88770025 0.808 NM_001146157
FAM25A
family with sequence similarity 25, member A
chr19_-_6621078 0.808 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr2_+_161873239 0.796 PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr6_-_35804337 0.783 NM_001145775
FKBP5
FK506 binding protein 5
chr1_-_223683141 0.779 NM_194442
LBR
lamin B receptor
chr2_-_86418716 0.772 NM_001164730
REEP1
receptor accessory protein 1
chr12_+_6514645 0.765 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr15_+_57691272 0.764 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_-_95184121 0.762 GLRX
glutaredoxin (thioltransferase)
chr6_-_24985432 0.761 NM_015864
FAM65B
family with sequence similarity 65, member B
chr17_+_77910411 0.759 NM_207459
TEX19
testis expressed 19
chr9_-_115880372 0.759 AMBP
alpha-1-microglobulin/bikunin precursor
chr1_-_244647333 0.758 NM_022743
SMYD3
SET and MYND domain containing 3
chr19_-_54350457 0.758 NM_002152
HRC
histidine rich calcium binding protein
chr4_-_191143017 0.755 NM_020040
TUBB4Q
tubulin, beta polypeptide 4, member Q
chr4_-_21308415 0.745 NM_001035003
KCNIP4
Kv channel interacting protein 4
chr1_-_94147537 0.740 GCLM
glutamate-cysteine ligase, modifier subunit
chr9_-_85512937 0.738 NM_013438
NM_053067
UBQLN1

ubiquilin 1

chr14_+_38772870 0.736 NM_054024
MIA2
melanoma inhibitory activity 2
chr1_-_172258129 0.734


chr1_-_94147574 0.730 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr2_+_119905812 0.729 NM_183240
TMEM37
transmembrane protein 37
chr12_-_46405477 0.720 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr20_+_41621119 0.713 SGK2
serum/glucocorticoid regulated kinase 2
chr6_+_32003380 0.712 C2
complement component 2
chr15_+_36776090 0.709 NM_207444
C15orf53
chromosome 15 open reading frame 53
chr19_+_56337368 0.701 NM_014385
NM_016543
SIGLEC7

sialic acid binding Ig-like lectin 7

chr15_-_81037554 0.699 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr22_+_21359175 0.698 IGLV3-25
immunoglobulin lambda variable 3-25
chr22_+_20316968 0.698 NM_152612
CCDC116
coiled-coil domain containing 116
chr6_-_31812283 0.696 CLIC1
chloride intracellular channel 1
chr6_-_31812072 0.696 CLIC1
chloride intracellular channel 1
chr7_+_111850367 0.692 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chrX_+_133198742 0.689 NM_001101357
CCDC160
coiled-coil domain containing 160
chr6_-_31812297 0.684 NM_001288
CLIC1
chloride intracellular channel 1
chr9_-_124329392 0.676 NM_012363
OR1N1
olfactory receptor, family 1, subfamily N, member 1
chr6_-_31812260 0.674 CLIC1
chloride intracellular channel 1
chr9_-_126309510 0.673 NM_004959
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr19_+_55398680 0.673 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr10_+_17891348 0.673 NM_001009567
NM_002438
MRC1L1
MRC1
mannose receptor, C type 1-like 1
mannose receptor, C type 1
chr2_-_70901186 0.670 NM_173535
CLEC4F
C-type lectin domain family 4, member F
chr7_+_130445394 0.668 NM_001145354
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr6_+_84626113 0.667 CYB5R4
cytochrome b5 reductase 4
chr14_+_57781308 0.663 NM_002788
NM_152132
PSMA3

proteasome (prosome, macropain) subunit, alpha type, 3

chr6_-_31812251 0.662 CLIC1
chloride intracellular channel 1
chr6_-_31812214 0.656 CLIC1
chloride intracellular channel 1
chr9_-_115880366 0.653 AMBP
alpha-1-microglobulin/bikunin precursor
chr12_-_101835026 0.651 PAH
phenylalanine hydroxylase
chr6_-_31812266 0.649 CLIC1
chloride intracellular channel 1
chr6_-_35996915 0.647 NM_003137
SRPK1
SRSF protein kinase 1
chr10_+_18138338 0.645 NM_001009567
NM_002438
MRC1L1
MRC1
mannose receptor, C type 1-like 1
mannose receptor, C type 1
chr19_-_6621598 0.645 NM_003807
NM_172014
TNFSF14

tumor necrosis factor (ligand) superfamily, member 14

chr6_+_44322831 0.642 HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr2_-_11402150 0.638 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr17_-_62793097 0.635 PSMD12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr7_-_76667045 0.629 NM_006682
FGL2
fibrinogen-like 2
chr9_-_85512674 0.628 UBQLN1
ubiquilin 1
chr5_+_145563305 0.626 RBM27
RNA binding motif protein 27
chr16_+_72888161 0.620 NM_002811
PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr5_+_150206277 0.614 NM_001145805
IRGM
immunity-related GTPase family, M
chr6_+_84626083 0.612 NM_016230
CYB5R4
cytochrome b5 reductase 4
chr15_+_42616665 0.608 EIF3J
eukaryotic translation initiation factor 3, subunit J
chr7_+_150319076 0.606 NM_000603
NOS3
nitric oxide synthase 3 (endothelial cell)
chr22_-_17846621 0.604 UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr6_+_36518778 0.603 KCTD20
potassium channel tetramerisation domain containing 20
chr4_-_977163 0.593 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr22_+_21495273 0.590


chr5_+_145563324 0.590 NM_018989
RBM27
RNA binding motif protein 27
chr17_+_44429748 0.589 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr22_-_17846725 0.588 NM_001035247
NM_005659
UFD1L

ubiquitin fusion degradation 1 like (yeast)

chr2_-_11523727 0.588 NM_198256
E2F6
E2F transcription factor 6
chr11_+_72660894 0.584 NM_004154
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chrX_-_72351348 0.583 NAP1L2
nucleosome assembly protein 1-like 2
chr6_+_44322764 0.579 NM_007355
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr14_+_57781352 0.576 PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr16_+_30326386 0.575 ZNF771
zinc finger protein 771
chr2_-_65447370 0.572 NM_001128210
SPRED2
sprouty-related, EVH1 domain containing 2
chr9_-_85512311 0.572 UBQLN1
ubiquilin 1
chr14_+_57781210 0.564 PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr2_+_161873031 0.563 NM_005805
PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr16_+_72888231 0.563 PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr8_+_22266256 0.561 PIWIL2
piwi-like 2 (Drosophila)
chr13_+_112746908 0.560 MCF2L
MCF.2 cell line derived transforming sequence-like
chr22_+_19699441 0.557 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr6_+_36518521 0.555 NM_173562
KCTD20
potassium channel tetramerisation domain containing 20
chr1_+_76024466 0.554 NM_004582
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr17_+_27795632 0.553 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr9_+_129962292 0.553 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr8_-_25371663 0.552 KCTD9
potassium channel tetramerisation domain containing 9
chr20_+_34937928 0.550 NM_080628
C20orf118
chromosome 20 open reading frame 118
chr8_-_11242408 0.546 LOC100129129
hypothetical LOC100129129
chr16_+_30326077 0.546 NM_001142305
NM_016643
ZNF771

zinc finger protein 771

chr17_-_53764867 0.545


chr9_-_115880281 0.542 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_-_80548378 0.539 NM_033214
GK2
glycerol kinase 2
chr12_-_51629874 0.539 KRT8
keratin 8
chr1_-_109770581 0.537 PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr1_+_67404756 0.536 NM_144701
IL23R
interleukin 23 receptor
chr7_-_100667750 0.535 NM_014343
CLDN15
claudin 15
chr2_-_11523666 0.535 E2F6
E2F transcription factor 6
chr3_+_185377341 0.534 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr6_-_31853027 0.534 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr12_-_74764614 0.530 NAP1L1
nucleosome assembly protein 1-like 1
chr22_-_17846711 0.526 UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr13_-_98757634 0.526 NM_004951
GPR183
G protein-coupled receptor 183
chrX_+_41078787 0.524 DDX3X
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr5_-_90645974 0.524 LOC100505994
hypothetical LOC100505994
chr9_-_115880425 0.523 AMBP
alpha-1-microglobulin/bikunin precursor
chr5_-_75954807 0.521 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr22_+_20880159 0.520 IGLV6-57
immunoglobulin lambda variable 6-57
chr3_-_39209075 0.519 NM_194293
NM_001198621
XIRP1

xin actin-binding repeat containing 1

chr9_-_115880494 0.517 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chrX_-_72351392 0.517 NM_021963
NAP1L2
nucleosome assembly protein 1-like 2
chr2_+_161873190 0.516 PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr14_+_102870431 0.513 EIF5
eukaryotic translation initiation factor 5
chr1_+_46151845 0.507 MAST2
microtubule associated serine/threonine kinase 2
chr6_-_24827265 0.505 NM_030939
C6orf62
chromosome 6 open reading frame 62
chrX_-_24575375 0.500 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr20_+_61337679 0.498 NM_022161
NM_139317
BIRC7

baculoviral IAP repeat containing 7

chr5_+_159368721 0.497 TTC1
tetratricopeptide repeat domain 1
chr6_-_30792830 0.492 MDC1
mediator of DNA-damage checkpoint 1
chr22_+_21559959 0.488 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chrX_-_119329334 0.487 NM_001104544
NM_001104545
NM_017938
FAM70A


family with sequence similarity 70, member A


chr11_-_123799976 0.486 NM_001005196
OR8B4
olfactory receptor, family 8, subfamily B, member 4
chr7_+_106991638 0.484 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr22_+_21065207 0.484 IGLJ3
immunoglobulin lambda joining 3
chr5_+_159368733 0.484 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr14_+_19655405 0.480 NM_001004715
OR4K17
olfactory receptor, family 4, subfamily K, member 17
chrX_-_24575146 0.480 PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr16_+_85983375 0.479 MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
chr6_-_170704251 0.478 PSMB1
proteasome (prosome, macropain) subunit, beta type, 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
6.92 1.98e-08 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
6.92 1.98e-08 GO:0072395 signal transduction involved in cell cycle checkpoint
6.92 1.98e-08 GO:0072401 signal transduction involved in DNA integrity checkpoint
6.92 1.98e-08 GO:0072404 signal transduction involved in G1/S transition checkpoint
6.92 1.98e-08 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
6.92 1.98e-08 GO:0072422 signal transduction involved in DNA damage checkpoint
6.92 1.98e-08 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
6.92 1.98e-08 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
6.60 5.11e-08 GO:0071158 positive regulation of cell cycle arrest
5.69 1.05e-07 GO:0051351 positive regulation of ligase activity
7.13 1.44e-07 GO:0006521 regulation of cellular amino acid metabolic process
6.21 1.66e-07 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
5.95 3.77e-07 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.42 7.74e-07 GO:2000045 regulation of G1/S transition of mitotic cell cycle
4.97 1.63e-06 GO:0051340 regulation of ligase activity
5.49 1.71e-06 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.42 2.17e-06 GO:0000216 M/G1 transition of mitotic cell cycle
5.42 2.17e-06 GO:0031575 mitotic cell cycle G1/S transition checkpoint
5.42 2.17e-06 GO:0051443 positive regulation of ubiquitin-protein ligase activity
5.42 2.17e-06 GO:0071779 G1/S transition checkpoint
4.66 2.38e-06 GO:0090068 positive regulation of cell cycle process
5.28 3.44e-06 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
5.91 3.84e-06 GO:0033238 regulation of cellular amine metabolic process
5.64 8.27e-06 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
4.91 1.25e-05 GO:0030330 DNA damage response, signal transduction by p53 class mediator
4.40 1.63e-05 GO:0000077 DNA damage checkpoint
5.40 1.70e-05 GO:0051352 negative regulation of ligase activity
5.40 1.70e-05 GO:0051444 negative regulation of ubiquitin-protein ligase activity
4.36 1.94e-05 GO:0042770 signal transduction in response to DNA damage
4.69 2.78e-05 GO:0051438 regulation of ubiquitin-protein ligase activity
4.13 5.33e-05 GO:0031570 DNA integrity checkpoint
4.12 1.21e-04 GO:0000084 S phase of mitotic cell cycle
4.12 1.21e-04 GO:0031398 positive regulation of protein ubiquitination
4.04 1.66e-04 GO:0051320 S phase
3.47 1.92e-04 GO:0010498 proteasomal protein catabolic process
3.47 1.92e-04 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
4.34 5.20e-04 GO:0031397 negative regulation of protein ubiquitination
2.15 9.96e-04 GO:0019725 cellular homeostasis
3.36 2.02e-03 GO:0000082 G1/S transition of mitotic cell cycle
3.31 2.56e-03 GO:0031396 regulation of protein ubiquitination
2.45 3.70e-03 GO:0019941 modification-dependent protein catabolic process
3.34 3.90e-03 GO:0010565 regulation of cellular ketone metabolic process
2.49 3.93e-03 GO:0031401 positive regulation of protein modification process
2.44 4.29e-03 GO:0043632 modification-dependent macromolecule catabolic process
3.41 5.24e-03 GO:0007093 mitotic cell cycle checkpoint
2.39 6.59e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
2.43 6.60e-03 GO:0006511 ubiquitin-dependent protein catabolic process
2.26 9.24e-03 GO:0032270 positive regulation of cellular protein metabolic process
2.34 1.00e-02 GO:0044257 cellular protein catabolic process
5.56 1.49e-02 GO:0051899 membrane depolarization
1.58 2.37e-02 GO:0035556 intracellular signal transduction
2.36 2.38e-02 GO:0051329 interphase of mitotic cell cycle
2.15 2.62e-02 GO:0051247 positive regulation of protein metabolic process
1.63 2.65e-02 GO:0050790 regulation of catalytic activity
3.15 2.88e-02 GO:0042391 regulation of membrane potential
2.32 3.35e-02 GO:0051325 interphase
1.12 3.81e-02 GO:0009987 cellular process
1.83 4.06e-02 GO:0043085 positive regulation of catalytic activity
2.87 4.09e-02 GO:0031400 negative regulation of protein modification process
2.19 4.13e-02 GO:0030163 protein catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
7.41 6.12e-11 GO:0000502 proteasome complex
8.89 4.06e-04 GO:0005839 proteasome core complex
1.17 2.05e-03 GO:0005737 cytoplasm
13.89 2.91e-03 GO:0019773 proteasome core complex, alpha-subunit complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
8.47 8.74e-04 GO:0004298 threonine-type endopeptidase activity
8.47 8.74e-04 GO:0070003 threonine-type peptidase activity
4.36 3.43e-02 GO:0005097 Rab GTPase activator activity