Motif ID: ATF5_CREB3.p2

Z-value: 1.308


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF5chr19_+_55124211-0.495.6e-02Click!
CREB3chr9_+_35722207-0.371.5e-01Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_171558143 2.205 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr3_+_101462375 1.800 NM_018309
TBC1D23
TBC1 domain family, member 23
chr3_+_142569988 1.727 ZBTB38
zinc finger and BTB domain containing 38
chr3_+_171558188 1.707 SKIL
SKI-like oncogene
chr3_+_44778284 1.705 KIF15
kinesin family member 15
chr17_+_52688842 1.681 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr3_+_171558215 1.654 SKIL
SKI-like oncogene
chr9_-_69729918 1.573 CBWD5
COBW domain containing 5
chr16_+_18986417 1.544 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr9_-_124066901 1.430 NM_033117
RBM18
RNA binding motif protein 18
chr5_+_56505412 1.414 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr9_-_124066838 1.408 RBM18
RNA binding motif protein 18
chr14_-_35348086 1.404 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr17_+_50697355 1.373 HLF
hepatic leukemia factor
chr5_+_56505608 1.326 GPBP1
GC-rich promoter binding protein 1
chr3_-_102878301 1.325 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr17_+_50697319 1.317 NM_002126
HLF
hepatic leukemia factor
chr14_+_67156405 1.306 ARG2
arginase, type II
chr14_+_67156386 1.300 ARG2
arginase, type II
chr2_+_208103068 1.290 CREB1
cAMP responsive element binding protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 87 entries
enrichment   p-value GO term description
4.02 2.09e-04 GO:0006888 ER to Golgi vesicle-mediated transport
2.51 1.69e-04 GO:0048193 Golgi vesicle transport
2.18 4.29e-04 GO:0000375 RNA splicing, via transesterification reactions
2.14 1.28e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.14 1.28e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
2.12 2.74e-06 GO:0008380 RNA splicing
2.10 1.23e-02 GO:0043687 post-translational protein modification
2.02 9.51e-03 GO:0006457 protein folding
1.94 5.51e-04 GO:0051329 interphase of mitotic cell cycle
1.93 4.05e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.93 6.29e-04 GO:0048285 organelle fission
1.93 9.79e-04 GO:0000280 nuclear division
1.93 9.79e-04 GO:0007067 mitosis
1.91 1.24e-03 GO:0000087 M phase of mitotic cell cycle
1.90 3.76e-04 GO:0070647 protein modification by small protein conjugation or removal
1.90 1.06e-03 GO:0051325 interphase
1.89 2.83e-08 GO:0000278 mitotic cell cycle
1.89 8.84e-04 GO:0019941 modification-dependent protein catabolic process
1.89 4.83e-02 GO:0009261 ribonucleotide catabolic process
1.88 1.14e-03 GO:0043632 modification-dependent macromolecule catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
4.84 3.83e-03 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.74 3.89e-02 GO:0005798 Golgi-associated vesicle
2.35 2.54e-02 GO:0000776 kinetochore
2.16 7.42e-03 GO:0005681 spliceosomal complex
2.07 1.45e-02 GO:0000775 chromosome, centromeric region
1.92 1.86e-02 GO:0005819 spindle
1.81 2.48e-02 GO:0005813 centrosome
1.75 2.14e-03 GO:0005815 microtubule organizing center
1.67 7.43e-04 GO:0044427 chromosomal part
1.62 5.74e-04 GO:0005694 chromosome
1.62 1.35e-03 GO:0030529 ribonucleoprotein complex
1.60 1.30e-10 GO:0005654 nucleoplasm
1.58 7.69e-05 GO:0044451 nucleoplasm part
1.58 1.98e-04 GO:0015630 microtubule cytoskeleton
1.56 9.33e-17 GO:0044428 nuclear part
1.56 1.66e-13 GO:0031981 nuclear lumen
1.56 9.62e-03 GO:0005730 nucleolus
1.50 1.74e-02 GO:0044431 Golgi apparatus part
1.49 1.30e-13 GO:0070013 intracellular organelle lumen
1.48 2.99e-13 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
2.08 2.57e-02 GO:0004386 helicase activity
1.89 4.79e-14 GO:0003723 RNA binding
1.58 3.67e-05 GO:0016462 pyrophosphatase activity
1.57 4.70e-05 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.57 5.99e-05 GO:0016817 hydrolase activity, acting on acid anhydrides
1.56 1.21e-04 GO:0017111 nucleoside-triphosphatase activity
1.51 7.86e-15 GO:0000166 nucleotide binding
1.50 7.56e-09 GO:0030554 adenyl nucleotide binding
1.50 1.21e-08 GO:0032559 adenyl ribonucleotide binding
1.49 4.03e-11 GO:0017076 purine nucleotide binding
1.49 5.62e-11 GO:0032553 ribonucleotide binding
1.49 5.62e-11 GO:0032555 purine ribonucleotide binding
1.49 9.55e-11 GO:0035639 purine ribonucleoside triphosphate binding
1.49 3.34e-08 GO:0005524 ATP binding
1.35 4.18e-11 GO:0003676 nucleic acid binding
1.25 1.99e-17 GO:0005515 protein binding
1.24 1.80e-02 GO:0003677 DNA binding
1.17 6.44e-04 GO:0003824 catalytic activity
1.12 1.75e-13 GO:0005488 binding