Motif ID: ATF5_CREB3.p2

Z-value: 1.308


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF5chr19_+_55124211-0.495.6e-02Click!
CREB3chr9_+_35722207-0.371.5e-01Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_171558143 2.205 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr3_+_101462375 1.800 NM_018309
TBC1D23
TBC1 domain family, member 23
chr3_+_142569988 1.727 ZBTB38
zinc finger and BTB domain containing 38
chr3_+_171558188 1.707 SKIL
SKI-like oncogene
chr3_+_44778284 1.705 KIF15
kinesin family member 15
chr17_+_52688842 1.681 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr3_+_171558215 1.654 SKIL
SKI-like oncogene
chr9_-_69729918 1.573 CBWD5
COBW domain containing 5
chr16_+_18986417 1.544 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr9_-_124066901 1.430 NM_033117
RBM18
RNA binding motif protein 18
chr5_+_56505412 1.414 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr9_-_124066838 1.408 RBM18
RNA binding motif protein 18
chr14_-_35348086 1.404 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr17_+_50697355 1.373 HLF
hepatic leukemia factor
chr5_+_56505608 1.326 GPBP1
GC-rich promoter binding protein 1
chr3_-_102878301 1.325 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr17_+_50697319 1.317 NM_002126
HLF
hepatic leukemia factor
chr14_+_67156405 1.306 ARG2
arginase, type II
chr14_+_67156386 1.300 ARG2
arginase, type II
chr2_+_208103068 1.290 CREB1
cAMP responsive element binding protein 1
chr3_+_142143329 1.288 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr17_-_55958274 1.287 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr3_-_44778099 1.287 NM_020696
KIAA1143
KIAA1143
chr3_+_44778212 1.259 NM_020242
KIF15
kinesin family member 15
chr5_-_95323353 1.233 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr1_+_110328830 1.226 NM_006621
AHCYL1
adenosylhomocysteinase-like 1
chr19_-_62043867 1.217 NM_001146326
NM_001146327
NM_015363
NM_001146184
NM_001146185
NM_001146187
NM_006210
ZIM2


PEG3



zinc finger, imprinted 2


paternally expressed 3



chr14_+_67156323 1.212 NM_001172
ARG2
arginase, type II
chr17_-_55958073 1.202 APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr2_+_60962206 1.201 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr7_-_156378382 1.198 LMBR1
limb region 1 homolog (mouse)
chr2_+_60962279 1.183 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr10_-_113933457 1.181 NM_020918
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr2_+_24003648 1.177 UBXN2A
UBX domain protein 2A
chr2_-_240613480 1.168 NM_004544
NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr4_-_80079393 1.165 NM_001040202
PAQR3
progestin and adipoQ receptor family member III
chr7_-_156378636 1.163 NM_022458
LMBR1
limb region 1 homolog (mouse)
chr2_-_38457884 1.162 ATL2
atlastin GTPase 2
chr2_-_38457934 1.147 NM_001135673
NM_022374
ATL2

atlastin GTPase 2

chr12_+_22669352 1.136 ETNK1
ethanolamine kinase 1
chr12_+_67290881 1.116 NM_001010942
NM_015646
RAP1B

RAP1B, member of RAS oncogene family

chr5_+_112877251 1.116 NM_022828
YTHDC2
YTH domain containing 2
chr20_+_18436548 1.108 NM_001172745
SEC23B
Sec23 homolog B (S. cerevisiae)
chr6_+_64340408 1.105 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr2_+_208103001 1.099 CREB1
cAMP responsive element binding protein 1
chr12_+_27288475 1.098 STK38L
serine/threonine kinase 38 like
chr12_+_27288446 1.092 STK38L
serine/threonine kinase 38 like
chr20_+_18436525 1.091 SEC23B
Sec23 homolog B (S. cerevisiae)
chr5_-_95323180 1.083 ELL2
elongation factor, RNA polymerase II, 2
chr17_+_54997667 1.082 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr17_+_64020120 1.075 NM_002734
NM_212472
PRKAR1A

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

chr2_-_25047988 1.057 DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr1_+_212227902 1.055 PROX1
prospero homeobox 1
chr2_-_24003403 1.050 NM_017552
ATAD2B
ATPase family, AAA domain containing 2B
chr4_-_39044300 1.043 NM_002913
RFC1
replication factor C (activator 1) 1, 145kDa
chr17_-_632135 1.027 NM_016080
GLOD4
glyoxalase domain containing 4
chrX_-_13866565 1.026 NM_001001994
GPM6B
glycoprotein M6B
chr12_+_67290975 1.025 RAP1B
RAP1B, member of RAS oncogene family
chr17_+_38238970 1.023 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr14_+_93562436 1.015 NM_023112
OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr14_+_93562500 1.015 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr8_+_17148755 1.014 NM_001145152
NM_152415
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr20_+_18436167 1.002 NM_006363
NM_032985
NM_032986
NM_001172746
SEC23B



Sec23 homolog B (S. cerevisiae)



chr8_+_64243741 0.999 YTHDF3
YTH domain family, member 3
chr7_-_129379947 0.995 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr2_-_278181 0.991 NM_001002919
FAM150B
family with sequence similarity 150, member B
chr8_+_64243662 0.990 NM_152758
YTHDF3
YTH domain family, member 3
chr17_+_54124952 0.990 NM_002876
NM_058216
RAD51C

RAD51 homolog C (S. cerevisiae)

chr6_+_64339869 0.988 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr19_+_47593137 0.988


chr3_-_151963607 0.979 SIAH2
seven in absentia homolog 2 (Drosophila)
chr10_+_24023680 0.975 NM_001098500
KIAA1217
KIAA1217
chr1_-_233879617 0.966 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr17_+_64020155 0.959 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr4_+_113777568 0.959 NM_016648
LARP7
La ribonucleoprotein domain family, member 7
chr6_-_53321545 0.949 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr3_+_187771139 0.944 NM_016306
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr17_+_55051818 0.940 NM_004859
CLTC
clathrin, heavy chain (Hc)
chr6_-_53321706 0.938 NM_021814
ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr20_+_34635362 0.936 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr4_-_123010918 0.933 NM_018190
NM_176824
BBS7

Bardet-Biedl syndrome 7

chr15_+_78139073 0.930 NM_019006
ZFAND6
zinc finger, AN1-type domain 6
chr2_-_160181206 0.925 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr14_-_35859545 0.915 NM_001144891
NM_016586
MBIP

MAP3K12 binding inhibitory protein 1

chr14_-_92720935 0.914 MOAP1
modulator of apoptosis 1
chr12_+_22669275 0.912 NM_001039481
NM_018638
ETNK1

ethanolamine kinase 1

chr21_-_43671355 0.909 NM_173354
SIK1
salt-inducible kinase 1
chr3_+_102775677 0.908 PCNP
PEST proteolytic signal containing nuclear protein
chr16_+_51722285 0.904 CHD9
chromodomain helicase DNA binding protein 9
chr8_+_61753793 0.899 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr11_+_4072635 0.897 RRM1
ribonucleotide reductase M1
chr22_-_25209761 0.885 NM_022081
HPS4
Hermansky-Pudlak syndrome 4
chr11_+_4072653 0.883 RRM1
ribonucleotide reductase M1
chr6_-_53321658 0.878 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr17_+_64020159 0.870 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr6_+_2190964 0.870


chr17_+_54124928 0.867 RAD51C
RAD51 homolog C (S. cerevisiae)
chr4_+_175441402 0.866 NM_001040157
KIAA1712
KIAA1712
chr22_+_25209812 0.857 NM_001013694
SRRD
SRR1 domain containing
chr1_-_31883051 0.855 PEF1
penta-EF-hand domain containing 1
chr2_+_108769572 0.853 NM_144978
CCDC138
coiled-coil domain containing 138
chr2_+_177785667 0.852 NM_194247
HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr11_+_95163256 0.852 NM_014679
CEP57
centrosomal protein 57kDa
chr2_-_241860871 0.840 HDLBP
high density lipoprotein binding protein
chr12_+_70120028 0.839 NM_003667
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr3_-_120665113 0.833 NM_018266
TMEM39A
transmembrane protein 39A
chr20_-_10602429 0.828 NM_000214
JAG1
jagged 1
chr4_-_56948345 0.825 NM_181806
AASDH
aminoadipate-semialdehyde dehydrogenase
chr2_+_108702338 0.823 NM_006267
RANBP2
RAN binding protein 2
chr2_-_240613357 0.814 NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr1_+_109090789 0.811 NM_007269
STXBP3
syntaxin binding protein 3
chrX_-_13866366 0.810


chr1_+_39229474 0.806 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr17_-_8092078 0.806 CTC1
CTS telomere maintenance complex component 1
chr16_+_18986721 0.803 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr7_-_23537968 0.799 NM_013293
TRA2A
transformer 2 alpha homolog (Drosophila)
chr17_+_26446067 0.798 NM_000267
NM_001042492
NM_001128147
NF1


neurofibromin 1


chr11_+_4072499 0.797 NM_001033
RRM1
ribonucleotide reductase M1
chr19_+_16048306 0.795 TPM4
tropomyosin 4
chr1_+_51855343 0.787 OSBPL9
oxysterol binding protein-like 9
chr6_-_122834580 0.785 NM_020755
SERINC1
serine incorporator 1
chr2_+_105320440 0.785 NM_024093
C2orf49
chromosome 2 open reading frame 49
chr11_-_111255020 0.785 FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr17_-_8092098 0.784 NM_025099
CTC1
CTS telomere maintenance complex component 1
chr3_+_187771192 0.784 DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr14_-_38642165 0.779 NM_006364
SEC23A
Sec23 homolog A (S. cerevisiae)
chr9_+_124066973 0.776 MRRF
mitochondrial ribosome recycling factor
chr16_+_20819488 0.769 NM_001128301
NM_001128302
LYRM1

LYR motif containing 1

chr6_+_64340388 0.769 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr3_+_38181972 0.764 NM_005109
OXSR1
oxidative-stress responsive 1
chr1_+_220857774 0.763 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr20_+_57948803 0.756 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr7_+_96473225 0.755 NM_005222
DLX6
distal-less homeobox 6
chr12_+_7174230 0.754 NM_014718
CLSTN3
calsyntenin 3
chr14_-_38971370 0.753 NM_203301
FBXO33
F-box protein 33
chr10_-_59697636 0.752 NM_152230
IPMK
inositol polyphosphate multikinase
chr12_-_100979869 0.752 CCDC53
coiled-coil domain containing 53
chr4_-_113777569 0.752 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr12_+_67290977 0.749 RAP1B
RAP1BL
RAP1B, member of RAS oncogene family
RAP1B, member of RAS oncogene family pseudogene
chr2_+_208102937 0.748 CREB1
cAMP responsive element binding protein 1
chr17_+_55052046 0.746 CLTC
clathrin, heavy chain (Hc)
chr9_+_70046658 0.746 NM_201453
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr1_-_183552833 0.745 IVNS1ABP
influenza virus NS1A binding protein
chr1_+_109090868 0.745 STXBP3
syntaxin binding protein 3
chr1_-_148868644 0.745 ENSA
endosulfine alpha
chrX_+_101910713 0.743 LOC100287765
hypothetical LOC100287765
chr18_+_18767275 0.739 NM_002894
RBBP8
retinoblastoma binding protein 8
chr4_+_153676857 0.737 DKFZP434I0714
hypothetical protein DKFZP434I0714
chrX_+_84385649 0.737 NM_021998
ZNF711
zinc finger protein 711
chr18_-_257987 0.736 NM_005131
THOC1
THO complex 1
chr14_-_35347791 0.732 RALGAPA1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr3_-_33734747 0.729 NM_015097
CLASP2
cytoplasmic linker associated protein 2
chr17_-_50854054 0.728 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr20_-_42584100 0.727 NM_006811
NM_198941
SERINC3

serine incorporator 3

chr17_+_26060617 0.723


chr6_+_30402599 0.723 NM_021253
TRIM39
tripartite motif containing 39
chr16_+_49139694 0.720 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr8_-_117837240 0.720 NM_003756
EIF3H
eukaryotic translation initiation factor 3, subunit H
chrX_+_24077782 0.719 ZFX
zinc finger protein, X-linked
chr8_-_17148637 0.719 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr1_+_169721260 0.718 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chrX_-_13745134 0.715 GPM6B
glycoprotein M6B
chr5_+_72897323 0.713 NM_032175
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr10_-_97406357 0.711 ALDH18A1
aldehyde dehydrogenase 18 family, member A1
chr1_-_148868713 0.710 NM_004436
NM_207042
NM_207043
NM_207044
NM_207168
ENSA




endosulfine alpha




chr12_+_81276406 0.708 NM_032230
C12orf26
chromosome 12 open reading frame 26
chr8_+_123863224 0.702 ZHX2
zinc fingers and homeoboxes 2
chr19_+_16048266 0.699 TPM4
tropomyosin 4
chr2_+_183289205 0.696 NM_018981
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr3_-_197293377 0.693 TFRC
transferrin receptor (p90, CD71)
chrX_+_24077649 0.692 NM_001178086
NM_001178095
NM_001178084
NM_001178085
NM_003410
ZFX




zinc finger protein, X-linked




chrX_-_54086318 0.689 NM_001184898
PHF8
PHD finger protein 8
chr4_-_186584031 0.689 NM_018359
UFSP2
UFM1-specific peptidase 2
chr5_+_139534812 0.688 NM_032412
C5orf32
chromosome 5 open reading frame 32
chr17_-_46553083 0.687 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr4_+_170778265 0.686 NM_001829
NM_173872
CLCN3

chloride channel 3

chr11_-_8636958 0.686 NM_014818
TRIM66
tripartite motif containing 66
chr8_+_110621092 0.685 NM_198120
EBAG9
estrogen receptor binding site associated, antigen, 9
chr12_+_27288344 0.685 NM_015000
STK38L
serine/threonine kinase 38 like
chr11_+_113776582 0.685 NM_016090
RBM7
RNA binding motif protein 7
chr2_+_191453813 0.684 GLS
glutaminase
chr3_+_38182120 0.684 OXSR1
oxidative-stress responsive 1
chr3_+_16281670 0.683 NM_138381
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr2_-_86704446 0.682 RNF103
ring finger protein 103
chr4_+_85723080 0.680 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr2_+_170149092 0.679 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr3_-_33734544 0.678 CLASP2
cytoplasmic linker associated protein 2
chr3_+_186786655 0.677 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr8_-_103493637 0.676 NM_015902
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr2_+_74610751 0.676 HTRA2
HtrA serine peptidase 2
chr17_+_55052060 0.676 CLTC
clathrin, heavy chain (Hc)
chr4_+_113778060 0.673 NM_015454
LARP7
La ribonucleoprotein domain family, member 7
chr14_+_44501083 0.672 NM_015091
FAM179B
family with sequence similarity 179, member B
chr5_-_72896964 0.671 ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr14_-_38642029 0.671 SEC23A
Sec23 homolog A (S. cerevisiae)
chr17_+_38238942 0.668 NM_005789
NM_176863
PSME3

proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

chr1_+_110328955 0.667 AHCYL1
adenosylhomocysteinase-like 1
chr1_-_183553083 0.666 NM_006469
IVNS1ABP
influenza virus NS1A binding protein
chr8_-_17148474 0.663 CNOT7
CCR4-NOT transcription complex, subunit 7
chr10_-_115923874 0.661 C10orf118
chromosome 10 open reading frame 118

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.49 6.10e-31 GO:0044260 cellular macromolecule metabolic process
1.37 3.53e-30 GO:0044237 cellular metabolic process
1.40 4.39e-24 GO:0043170 macromolecule metabolic process
1.32 1.53e-22 GO:0044238 primary metabolic process
1.29 3.23e-22 GO:0008152 metabolic process
1.50 1.40e-16 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52 1.33e-15 GO:0044267 cellular protein metabolic process
1.55 2.47e-15 GO:0090304 nucleic acid metabolic process
1.43 8.49e-15 GO:0034641 cellular nitrogen compound metabolic process
1.40 5.06e-13 GO:0006807 nitrogen compound metabolic process
1.57 6.62e-13 GO:0010467 gene expression
1.56 5.92e-11 GO:0034645 cellular macromolecule biosynthetic process
1.13 7.33e-11 GO:0009987 cellular process
1.55 8.13e-11 GO:0009059 macromolecule biosynthetic process
1.53 2.65e-10 GO:0016070 RNA metabolic process
1.37 8.44e-10 GO:0019538 protein metabolic process
1.79 2.60e-09 GO:0046907 intracellular transport
1.41 6.35e-09 GO:0044249 cellular biosynthetic process
1.66 1.27e-08 GO:0007049 cell cycle
1.58 1.99e-08 GO:0051641 cellular localization
1.89 2.83e-08 GO:0000278 mitotic cell cycle
1.72 1.04e-07 GO:0022402 cell cycle process
1.37 1.42e-07 GO:0009058 biosynthetic process
1.60 1.62e-07 GO:0051649 establishment of localization in cell
1.80 3.22e-07 GO:0006396 RNA processing
1.76 5.05e-07 GO:0022403 cell cycle phase
1.43 1.04e-06 GO:0006464 protein modification process
1.55 1.40e-06 GO:0044248 cellular catabolic process
1.84 1.82e-06 GO:0016071 mRNA metabolic process
1.40 2.61e-06 GO:0043412 macromolecule modification
2.12 2.74e-06 GO:0008380 RNA splicing
1.29 3.21e-06 GO:0060255 regulation of macromolecule metabolic process
1.62 4.64e-06 GO:0045184 establishment of protein localization
1.27 6.86e-06 GO:0031323 regulation of cellular metabolic process
1.61 1.51e-05 GO:0015031 protein transport
1.46 1.60e-05 GO:0009056 catabolic process
1.47 2.19e-05 GO:0033036 macromolecule localization
1.25 2.21e-05 GO:0019222 regulation of metabolic process
1.77 3.24e-05 GO:0044265 cellular macromolecule catabolic process
1.70 5.39e-05 GO:0009057 macromolecule catabolic process
1.51 7.61e-05 GO:0008104 protein localization
1.40 1.13e-04 GO:0006996 organelle organization
1.32 1.15e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.25 1.20e-04 GO:0080090 regulation of primary metabolic process
1.30 1.28e-04 GO:0010468 regulation of gene expression
2.51 1.69e-04 GO:0048193 Golgi vesicle transport
4.02 2.09e-04 GO:0006888 ER to Golgi vesicle-mediated transport
1.29 2.09e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.85 2.54e-04 GO:0006397 mRNA processing
1.90 3.76e-04 GO:0070647 protein modification by small protein conjugation or removal
1.93 4.05e-04 GO:0006511 ubiquitin-dependent protein catabolic process
2.18 4.29e-04 GO:0000375 RNA splicing, via transesterification reactions
1.94 5.51e-04 GO:0051329 interphase of mitotic cell cycle
1.29 5.86e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.93 6.29e-04 GO:0048285 organelle fission
1.28 7.38e-04 GO:0031326 regulation of cellular biosynthetic process
1.89 8.84e-04 GO:0019941 modification-dependent protein catabolic process
1.93 9.79e-04 GO:0000280 nuclear division
1.93 9.79e-04 GO:0007067 mitosis
1.90 1.06e-03 GO:0051325 interphase
1.30 1.08e-03 GO:0051252 regulation of RNA metabolic process
1.88 1.14e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.27 1.20e-03 GO:0009889 regulation of biosynthetic process
1.91 1.24e-03 GO:0000087 M phase of mitotic cell cycle
2.14 1.28e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.14 1.28e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
1.74 1.78e-03 GO:0000279 M phase
1.67 1.99e-03 GO:0070727 cellular macromolecule localization
1.27 2.01e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.77 2.22e-03 GO:0006886 intracellular protein transport
1.84 2.29e-03 GO:0044257 cellular protein catabolic process
1.84 2.38e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
1.66 2.83e-03 GO:0034613 cellular protein localization
1.79 3.19e-03 GO:0030163 protein catabolic process
1.51 3.37e-03 GO:0033554 cellular response to stress
1.49 4.30e-03 GO:0006351 transcription, DNA-dependent
1.22 5.32e-03 GO:0071840 cellular component organization or biogenesis
1.29 6.57e-03 GO:0006355 regulation of transcription, DNA-dependent
2.02 9.51e-03 GO:0006457 protein folding
2.10 1.23e-02 GO:0043687 post-translational protein modification
1.24 1.36e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.42 2.69e-02 GO:0032774 RNA biosynthetic process
1.87 2.91e-02 GO:0072523 purine-containing compound catabolic process
1.48 2.97e-02 GO:0016192 vesicle-mediated transport
1.80 3.99e-02 GO:0032446 protein modification by small protein conjugation
1.20 4.33e-02 GO:0016043 cellular component organization
1.89 4.83e-02 GO:0009261 ribonucleotide catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.22 8.08e-42 GO:0044424 intracellular part
1.21 1.06e-39 GO:0005622 intracellular
1.29 5.57e-38 GO:0043231 intracellular membrane-bounded organelle
1.29 1.08e-37 GO:0043227 membrane-bounded organelle
1.25 7.92e-34 GO:0043229 intracellular organelle
1.24 2.40e-33 GO:0043226 organelle
1.25 6.85e-25 GO:0005737 cytoplasm
1.35 1.07e-23 GO:0044446 intracellular organelle part
1.35 3.71e-23 GO:0044422 organelle part
1.34 1.35e-21 GO:0005634 nucleus
1.28 3.73e-17 GO:0044444 cytoplasmic part
1.56 9.33e-17 GO:0044428 nuclear part
1.49 1.30e-13 GO:0070013 intracellular organelle lumen
1.56 1.66e-13 GO:0031981 nuclear lumen
1.48 2.99e-13 GO:0031974 membrane-enclosed lumen
1.48 3.36e-13 GO:0043233 organelle lumen
1.60 1.30e-10 GO:0005654 nucleoplasm
1.30 7.88e-09 GO:0032991 macromolecular complex
1.41 1.93e-08 GO:0005829 cytosol
1.28 8.10e-06 GO:0043234 protein complex
1.58 7.69e-05 GO:0044451 nucleoplasm part
1.32 9.51e-05 GO:0031090 organelle membrane
1.58 1.98e-04 GO:0015630 microtubule cytoskeleton
1.62 5.74e-04 GO:0005694 chromosome
1.67 7.43e-04 GO:0044427 chromosomal part
1.62 1.35e-03 GO:0030529 ribonucleoprotein complex
1.75 2.14e-03 GO:0005815 microtubule organizing center
1.24 2.50e-03 GO:0043228 non-membrane-bounded organelle
1.24 2.50e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.40 2.56e-03 GO:0005783 endoplasmic reticulum
1.04 2.76e-03 GO:0044464 cell part
1.32 2.83e-03 GO:0012505 endomembrane system
1.04 2.86e-03 GO:0005623 cell
4.84 3.83e-03 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.40 7.35e-03 GO:0005794 Golgi apparatus
2.16 7.42e-03 GO:0005681 spliceosomal complex
1.56 9.62e-03 GO:0005730 nucleolus
2.07 1.45e-02 GO:0000775 chromosome, centromeric region
1.50 1.74e-02 GO:0044431 Golgi apparatus part
1.92 1.86e-02 GO:0005819 spindle
1.81 2.48e-02 GO:0005813 centrosome
2.35 2.54e-02 GO:0000776 kinetochore
2.74 3.89e-02 GO:0005798 Golgi-associated vesicle
1.41 4.15e-02 GO:0044432 endoplasmic reticulum part
1.42 4.30e-02 GO:0016023 cytoplasmic membrane-bounded vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.25 1.99e-17 GO:0005515 protein binding
1.51 7.86e-15 GO:0000166 nucleotide binding
1.89 4.79e-14 GO:0003723 RNA binding
1.12 1.75e-13 GO:0005488 binding
1.49 4.03e-11 GO:0017076 purine nucleotide binding
1.35 4.18e-11 GO:0003676 nucleic acid binding
1.49 5.62e-11 GO:0032553 ribonucleotide binding
1.49 5.62e-11 GO:0032555 purine ribonucleotide binding
1.49 9.55e-11 GO:0035639 purine ribonucleoside triphosphate binding
1.50 7.56e-09 GO:0030554 adenyl nucleotide binding
1.50 1.21e-08 GO:0032559 adenyl ribonucleotide binding
1.49 3.34e-08 GO:0005524 ATP binding
1.58 3.67e-05 GO:0016462 pyrophosphatase activity
1.57 4.70e-05 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.57 5.99e-05 GO:0016817 hydrolase activity, acting on acid anhydrides
1.56 1.21e-04 GO:0017111 nucleoside-triphosphatase activity
1.17 6.44e-04 GO:0003824 catalytic activity
1.24 1.80e-02 GO:0003677 DNA binding
2.08 2.57e-02 GO:0004386 helicase activity