Motif ID: NR1H4.p2

Z-value: 1.024


Transcription factors associated with NR1H4.p2:

Gene SymbolEntrez IDGene Name
NR1H4 9971 nuclear receptor subfamily 1, group H, member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR1H4chr12_+_993918700.146.2e-01Click!


Activity profile for motif NR1H4.p2.

activity profile for motif NR1H4.p2


Sorted Z-values histogram for motif NR1H4.p2

Sorted Z-values for motif NR1H4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1H4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_149750485 1.311 NM_020770
CGN
cingulin
chrX_-_106033202 1.231 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr9_-_66233945 1.227


chr6_-_33016561 1.222 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr9_+_83748234 1.165 NM_207416
FAM75D3
family with sequence similarity 75, member D3
chrX_-_70755023 1.134 NM_001142797
NM_001504
CXCR3

chemokine (C-X-C motif) receptor 3

chr17_+_56884560 1.125 TBX4
T-box 4
chr3_+_52803823 1.021 NM_002217
ITIH3
inter-alpha (globulin) inhibitor H3
chr1_+_32512298 1.020 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr1_+_32489426 1.018 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr12_+_58369392 0.988 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr3_-_58627509 0.988 NM_138805
FAM3D
family with sequence similarity 3, member D
chr12_-_16321885 0.986 NM_001170798
SLC15A5
solute carrier family 15, member 5
chrX_+_128741562 0.956 NM_018990
SASH3
SAM and SH3 domain containing 3
chr17_+_7883076 0.930 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr1_+_12046020 0.911 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr1_-_36562341 0.903 NM_018166
FAM176B
family with sequence similarity 176, member B
chr19_-_63556632 0.857 NM_130786
A1BG
alpha-1-B glycoprotein
chr11_-_6633427 0.848 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr16_-_3025542 0.848 NM_001103175
CCDC64B
coiled-coil domain containing 64B
chr5_-_177355848 0.840 NM_006261
PROP1
PROP paired-like homeobox 1
chr7_+_2638108 0.819 NM_025250
TTYH3
tweety homolog 3 (Drosophila)
chr19_-_11550765 0.791 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr8_+_11388918 0.784 NM_001715
BLK
B lymphoid tyrosine kinase
chr11_-_6148131 0.783 NM_001004052
OR52B2
olfactory receptor, family 52, subfamily B, member 2
chrX_+_7147471 0.783 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr4_-_40326603 0.779 NM_001098634
RBM47
RNA binding motif protein 47
chr17_+_71487080 0.779 C17orf106
chromosome 17 open reading frame 106
chr3_+_112743729 0.778 CD96
CD96 molecule
chr7_+_150376537 0.777 NM_004769
NM_020321
NM_020322
ACCN3


amiloride-sensitive cation channel 3


chr17_+_18796202 0.776 NM_001042450
NM_152351
SLC5A10

solute carrier family 5 (sodium/glucose cotransporter), member 10

chr7_+_2638156 0.760 TTYH3
tweety homolog 3 (Drosophila)
chr19_-_56585603 0.753 NM_001193623
LOC147646
hypothetical protein LOC147646
chr12_-_56422120 0.752 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr14_+_92869317 0.747 NM_020818
KIAA1409
KIAA1409
chr3_+_112743615 0.747 NM_005816
NM_198196
CD96

CD96 molecule

chr9_+_35032222 0.746 NM_001040410
NM_203299
C9orf131

chromosome 9 open reading frame 131

chr6_-_32268267 0.743 GPSM3
G-protein signaling modulator 3
chr8_-_57521702 0.743 NM_001135690
PENK
proenkephalin
chr3_-_127719283 0.741 NM_001165974
NM_144639
UROC1

urocanase domain containing 1

chr1_-_25128951 0.734 RUNX3
runt-related transcription factor 3
chr6_+_24465109 0.728 NM_181337
KAAG1
kidney associated antigen 1
chr5_-_176258920 0.719 NM_002115
HK3
hexokinase 3 (white cell)
chr3_+_123779122 0.710 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr14_-_54977015 0.710 NM_199047
TBPL2
TATA box binding protein like 2
chr1_+_93830169 0.706 LOC100129046
hypothetical LOC100129046
chr11_-_6298284 0.697 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr6_-_49789204 0.696 NM_001142407
NM_001142408
NM_001142417
NM_001142435
NM_003296
CRISP2




cysteine-rich secretory protein 2




chr19_-_52710129 0.694 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr11_+_60391590 0.692 NM_207341
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr10_+_46413551 0.674 NM_014696
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr3_+_46717826 0.667 NM_147196
TMIE
transmembrane inner ear
chr15_+_38437703 0.663 NM_033510
DISP2
dispatched homolog 2 (Drosophila)
chr17_+_7474177 0.660 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr3_-_50357994 0.658 NM_015896
ZMYND10
zinc finger, MYND-type containing 10
chr17_+_76827699 0.657 NM_001086521
C17orf89
chromosome 17 open reading frame 89
chr11_+_63337607 0.654 C11orf84
chromosome 11 open reading frame 84
chr11_+_64114857 0.648 NM_144585
NM_153378
SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

chr1_-_25129354 0.646 NM_004350
RUNX3
runt-related transcription factor 3
chr14_-_73962557 0.640 NM_001105579
TMEM90A
transmembrane protein 90A
chr5_-_33928049 0.638 ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr1_-_150070849 0.637 NM_005060
RORC
RAR-related orphan receptor C
chrX_-_65752570 0.636 NM_021783
EDA2R
ectodysplasin A2 receptor
chr6_-_33655811 0.634 BAK1
BCL2-antagonist/killer 1
chr9_-_129557373 0.633 NM_001142534
NM_001142533
SH2D3C

SH2 domain containing 3C

chr1_+_31814712 0.632 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr19_-_15451203 0.629 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr17_-_77421980 0.627 NM_001185077
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr5_-_33927724 0.621 NM_030955
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr5_+_145296313 0.617 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr19_+_4180494 0.607 NM_005755
EBI3
Epstein-Barr virus induced 3
chr12_-_51528983 0.607 NM_173352
KRT78
keratin 78
chr2_-_110231431 0.604 NM_005434
MALL
mal, T-cell differentiation protein-like
chr9_-_70345549 0.603 NM_153237
C9orf71
chromosome 9 open reading frame 71
chr10_-_50269912 0.591 NM_001080520
DRGX
dorsal root ganglia homeobox
chr5_+_139924595 0.591 NM_080670
SLC35A4
solute carrier family 35, member A4
chr11_+_61389756 0.589 FADS2
fatty acid desaturase 2
chr17_+_71486895 0.588 NM_001113324
C17orf106
C17orf106-CDK3
chromosome 17 open reading frame 106
C17orf106-CDK3 read-through transcript
chr17_-_4792971 0.587 PFN1
profilin 1
chr17_-_71535076 0.585 NM_001988
EVPL
envoplakin
chr17_-_2250967 0.576 NM_020310
MNT
MAX binding protein
chr22_+_29151651 0.575 NM_001003704
NM_016498
MTFP1

mitochondrial fission process 1

chr15_+_72540655 0.565 LOC440288
similar to FLJ16518 protein
chr22_-_49315341 0.565 NM_001113755
NM_001953
TYMP

thymidine phosphorylase

chr19_+_11407485 0.555 PRKCSH
protein kinase C substrate 80K-H
chr12_-_14982708 0.554 NM_152321
ERP27
endoplasmic reticulum protein 27
chr1_+_31814672 0.554 NM_022164
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr19_+_59107802 0.553 NM_031896
CACNG7
calcium channel, voltage-dependent, gamma subunit 7
chr16_-_65775326 0.549 NM_001040715
KIAA0895L
KIAA0895-like
chr6_-_38715901 0.549 NM_001099272
NM_052893
BTBD9

BTB (POZ) domain containing 9

chrX_+_102918453 0.548 PLP1
proteolipid protein 1
chr1_+_15941503 0.548 NM_001013641
TMEM82
transmembrane protein 82
chr16_-_3049336 0.541


chr19_-_17377383 0.540 NM_004335
BST2
bone marrow stromal cell antigen 2
chr17_-_35017650 0.539 NEUROD2
neurogenic differentiation 2
chr6_-_38715613 0.538 BTBD9
BTB (POZ) domain containing 9
chr8_-_37576515 0.537 LOC157860
hypothetical protein LOC157860
chr16_+_66131247 0.535 FAM65A
family with sequence similarity 65, member A
chr17_-_40674883 0.529


chr17_-_6279149 0.524 NM_001033054
NM_001033055
NM_014336
AIPL1


aryl hydrocarbon receptor interacting protein-like 1


chr16_-_66258072 0.524 NM_032140
C16orf48
chromosome 16 open reading frame 48
chr17_+_38430773 0.520 NM_005440
RND2
Rho family GTPase 2
chr17_-_71534906 0.520 EVPL
envoplakin
chr11_-_118582098 0.520 CCDC153
coiled-coil domain containing 153
chr1_+_11749385 0.518 C1orf167
chromosome 1 open reading frame 167
chr6_-_31432877 0.517 HLA-B
major histocompatibility complex, class I, B
chr5_-_171547844 0.517 STK10
serine/threonine kinase 10
chr2_+_218929822 0.504 NM_198559
C2orf62
chromosome 2 open reading frame 62
chrX_-_49851743 0.503 NM_139289
AKAP4
A kinase (PRKA) anchor protein 4
chr16_-_73012740 0.496 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr6_-_133126278 0.495 NM_078488
VNN2
vanin 2
chr5_-_66528330 0.495 NM_005582
CD180
CD180 molecule
chr9_+_83733162 0.495 NM_001145197
FAM75D4
family with sequence similarity 75, member D4
chr3_-_49826221 0.492 UBA7
ubiquitin-like modifier activating enzyme 7
chr17_+_18588050 0.492 NM_031456
FBXW10
CDRT1
F-box and WD repeat domain containing 10
CMT1A duplicated region transcript 1
chr2_-_27215781 0.491 NM_178553
C2orf53
chromosome 2 open reading frame 53
chr17_-_29930431 0.490 NM_207454
C17orf102
chromosome 17 open reading frame 102
chr20_+_30103642 0.488 NM_001172129
NM_001172130
NM_001172131
NM_001172132
NM_001172133
NM_002110
HCK





hemopoietic cell kinase





chr14_-_19252330 0.487 NM_001197287
OR11H2
olfactory receptor, family 11, subfamily H, member 2
chr15_+_88345612 0.486 NM_198526
ZNF710
zinc finger protein 710
chr14_+_64076916 0.486 NM_021979
HSPA2
heat shock 70kDa protein 2
chr14_-_90780604 0.480 NM_001177676
GPR68
G protein-coupled receptor 68
chr10_-_95350949 0.478 NM_006744
RBP4
retinol binding protein 4, plasma
chr9_+_115382990 0.470 RGS3
regulator of G-protein signaling 3
chr3_+_52464686 0.469 NISCH
nischarin
chr1_+_31814709 0.467 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr7_+_73136254 0.465 LIMK1
LIM domain kinase 1
chr19_+_40895669 0.464 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr17_+_7474128 0.462 SHBG
sex hormone-binding globulin
chr3_+_52464543 0.462 NM_007184
NISCH
nischarin
chr9_-_136949531 0.461 NM_002003
FCN1
ficolin (collagen/fibrinogen domain containing) 1
chr5_+_145297490 0.461 SH3RF2
SH3 domain containing ring finger 2
chr2_-_213723298 0.460 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr17_+_18221803 0.459 NM_001145127
EVPLL
envoplakin-like
chr6_-_33655995 0.459 NM_001188
BAK1
BCL2-antagonist/killer 1
chr11_+_7229717 0.458 NM_175733
SYT9
synaptotagmin IX
chr8_-_143692814 0.456 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr9_-_135074364 0.453 NM_014581
OBP2B
OBP2A
odorant binding protein 2B
odorant binding protein 2A
chrX_+_102918409 0.447 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr12_+_6768966 0.445 CD4
CD4 molecule
chr17_+_75776193 0.441 NM_052819
CARD14
caspase recruitment domain family, member 14
chrX_-_132376660 0.438 NM_001448
GPC4
glypican 4
chr19_+_50086350 0.437 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr22_+_23329113 0.436 NM_001032364
NM_005265
GGT1

gamma-glutamyltransferase 1

chr1_+_77105709 0.435 ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr9_-_139235595 0.435 NM_031297
RNF208
ring finger protein 208
chr7_+_49783774 0.434 NM_198570
VWC2
von Willebrand factor C domain containing 2
chrX_+_151975518 0.432 PNMA3
paraneoplastic antigen MA3
chr9_+_20648307 0.432 NM_017794
KIAA1797
KIAA1797
chrX_+_102918089 0.429 NM_001128834
PLP1
proteolipid protein 1
chr1_+_202000906 0.424 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr14_-_90789919 0.424 NM_003485
GPR68
G protein-coupled receptor 68
chr17_-_9880729 0.424 NM_201432
GAS7
growth arrest-specific 7
chr9_+_73716347 0.423 C9orf85
chromosome 9 open reading frame 85
chr10_-_105202139 0.421 NM_015916
CALHM2
calcium homeostasis modulator 2
chr3_+_52464657 0.420 NISCH
nischarin
chr7_-_127788893 0.419 NM_001114726
NM_001174164
PRRT4

proline-rich transmembrane protein 4

chr17_-_70367479 0.419 NM_000835
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr1_+_246591505 0.419 NM_001004696
OR2T4
olfactory receptor, family 2, subfamily T, member 4
chr3_+_133518900 0.417 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr14_-_23968570 0.417 NM_001039771
CBLN3
cerebellin 3 precursor
chr12_-_56159631 0.417 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chrX_+_151975421 0.416 NM_013364
PNMA3
paraneoplastic antigen MA3
chr7_-_44165398 0.414 NM_033507
NM_033508
GCK

glucokinase (hexokinase 4)

chr12_+_6768866 0.412 NM_000616
CD4
CD4 molecule
chr14_+_95222506 0.411 NM_004918
NM_199206
TCL1B

T-cell leukemia/lymphoma 1B

chr7_+_142136892 0.409 NM_002769
PRSS1
PRSS2
protease, serine, 1 (trypsin 1)
protease, serine, 2 (trypsin 2)
chr6_+_35812836 0.408 NM_145028
C6orf81
chromosome 6 open reading frame 81
chr5_-_139924013 0.406 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr19_+_59077241 0.405 NM_002739
PRKCG
protein kinase C, gamma
chr11_+_66381451 0.403 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr12_+_11694172 0.402 ETV6
ets variant 6
chr17_+_37942034 0.401


chr12_+_54798236 0.399 NM_032786
ZC3H10
zinc finger CCCH-type containing 10
chr6_+_107456020 0.396 NM_001142468
NM_001142470
NM_016487
C6orf203


chromosome 6 open reading frame 203


chr5_+_174084137 0.396 NM_002449
MSX2
msh homeobox 2
chr1_-_148174722 0.395 NM_181873
MTMR11
myotubularin related protein 11
chr16_+_66258205 0.395 NM_001012984
C16orf86
chromosome 16 open reading frame 86
chr4_+_100957003 0.391 NM_014395
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr3_-_49133254 0.391 USP19
ubiquitin specific peptidase 19
chr19_-_53558961 0.390 NM_018273
TMEM143
transmembrane protein 143
chr2_-_85490997 0.390 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr3_+_128874458 0.387 NM_172027
ABTB1
ankyrin repeat and BTB (POZ) domain containing 1
chr1_-_37272295 0.385 NM_000831
GRIK3
glutamate receptor, ionotropic, kainate 3
chr12_+_6768934 0.385 NM_001195014
NM_001195015
NM_001195016
NM_001195017
CD4



CD4 molecule



chr12_+_54798319 0.384 ZC3H10
zinc finger CCCH-type containing 10
chr5_-_171547804 0.382 STK10
serine/threonine kinase 10
chrX_+_106030049 0.381 NM_001171092
CLDN2
claudin 2
chr17_+_39778016 0.380 NM_002087
GRN
granulin
chr6_+_30082331 0.379 HLA-J
major histocompatibility complex, class I, J (pseudogene)
chr6_-_38715567 0.378 BTBD9
BTB (POZ) domain containing 9
chr2_+_27225362 0.376 NM_175769
TCF23
transcription factor 23
chr14_-_36121536 0.376 NM_014360
NKX2-8
NK2 homeobox 8
chr19_+_45807909 0.375


chrX_+_90977115 0.375 NM_001168360
NM_001168361
NM_001168362
NM_001168363
PCDH11X



protocadherin 11 X-linked



chrX_+_117841761 0.373 NM_173798
ZCCHC12
zinc finger, CCHC domain containing 12
chr9_-_34371497 0.372 NM_147168
NM_147169
C9orf24

chromosome 9 open reading frame 24

chrX_-_44945025 0.371 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr22_+_42751487 0.370 NM_013327
PARVB
parvin, beta
chr17_-_59561207 0.368 NM_001433
ERN1
endoplasmic reticulum to nucleus signaling 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 2.39e-02 GO:0016020 membrane
1.13 3.58e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.65 4.89e-05 GO:0003823 antigen binding