Motif ID: NFATC1..3.p2

Z-value: 1.465


Transcription factors associated with NFATC1..3.p2:

Gene SymbolEntrez IDGene Name
NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 4773 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 4775 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFATC3chr16_+_66676833-0.721.6e-03Click!
NFATC2chr20_-_49612745-0.591.7e-02Click!
NFATC1chr18_+_752567020.224.2e-01Click!


Activity profile for motif NFATC1..3.p2.

activity profile for motif NFATC1..3.p2


Sorted Z-values histogram for motif NFATC1..3.p2

Sorted Z-values for motif NFATC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_13240987 3.871 EMP1
epithelial membrane protein 1
chr12_+_13240868 3.506 NM_001423
 EMP1
epithelial membrane protein 1
chr2_-_237987579 2.032 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
 COL6A3




collagen, type VI, alpha 3




chr3_+_120799411 1.899 NM_015900
 PLA1A
phospholipase A1 member A
chr1_+_157246305 1.888 NM_005531
 IFI16
interferon, gamma-inducible protein 16
chr2_-_237987554 1.871 COL6A3
collagen, type VI, alpha 3
chr2_-_237987545 1.812 COL6A3
collagen, type VI, alpha 3
chr2_-_237987509 1.789 COL6A3
collagen, type VI, alpha 3
chr2_+_189547377 1.730 COL3A1
collagen, type III, alpha 1
chr2_+_189547358 1.649 COL3A1
collagen, type III, alpha 1
chr2_+_189547323 1.593 NM_000090
 COL3A1
collagen, type III, alpha 1
chr9_+_74956494 1.548 NM_000700
 ANXA1
annexin A1
chr4_+_183482130 1.418 NM_001080477
 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr1_+_100957883 1.394 NM_001078
NM_080682
 VCAM1

vascular cell adhesion molecule 1

chr15_+_37330176 1.332 NM_207445
 C15orf54
chromosome 15 open reading frame 54
chr4_-_149582948 1.319 NM_000901
NM_001166104
 NR3C2

nuclear receptor subfamily 3, group C, member 2

chr2_-_237987553 1.254 COL6A3
collagen, type VI, alpha 3
chr6_+_106653429 1.199 NM_182907
 PRDM1
PR domain containing 1, with ZNF domain
chr12_+_99274987 1.195 NM_001145288
NM_139319
 SLC17A8

solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8

chr4_-_149582754 1.189 NR3C2
nuclear receptor subfamily 3, group C, member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
3.26 3.07e-03 GO:0030595 leukocyte chemotaxis
2.81 4.52e-02 GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
2.76 1.96e-08 GO:0007156 homophilic cell adhesion
2.18 8.78e-04 GO:0050900 leukocyte migration
2.12 6.80e-08 GO:0016337 cell-cell adhesion
1.99 4.88e-02 GO:0043062 extracellular structure organization
1.84 5.95e-03 GO:0050865 regulation of cell activation
1.81 1.67e-02 GO:0002694 regulation of leukocyte activation
1.80 1.71e-11 GO:0007155 cell adhesion
1.80 1.71e-11 GO:0022610 biological adhesion
1.74 1.83e-02 GO:0006954 inflammatory response
1.66 2.47e-03 GO:0007608 sensory perception of smell
1.61 4.65e-03 GO:0007606 sensory perception of chemical stimulus
1.44 2.77e-03 GO:0009611 response to wounding
1.33 3.47e-02 GO:0002376 immune system process
1.28 2.11e-02 GO:0003008 system process
1.17 1.63e-04 GO:0032501 multicellular organismal process
1.14 7.11e-04 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.94 1.00e-06 GO:0005578 proteinaceous extracellular matrix
1.76 3.32e-05 GO:0031012 extracellular matrix
1.60 4.95e-02 GO:0044456 synapse part
1.55 1.19e-08 GO:0044421 extracellular region part
1.44 8.89e-04 GO:0005615 extracellular space
1.40 2.75e-10 GO:0005576 extracellular region
1.34 1.66e-17 GO:0005886 plasma membrane
1.33 5.02e-17 GO:0071944 cell periphery
1.32 1.14e-06 GO:0044459 plasma membrane part
1.19 8.39e-10 GO:0044425 membrane part
1.19 1.90e-07 GO:0031224 intrinsic to membrane
1.18 2.03e-06 GO:0016021 integral to membrane
1.13 1.25e-06 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.86 6.44e-03 GO:0005125 cytokine activity
1.68 5.26e-04 GO:0004984 olfactory receptor activity
1.61 2.55e-02 GO:0003779 actin binding
1.60 6.94e-06 GO:0005509 calcium ion binding
1.59 2.27e-07 GO:0004930 G-protein coupled receptor activity
1.50 1.11e-08 GO:0004888 transmembrane receptor activity
1.48 2.18e-11 GO:0004872 receptor activity
1.43 1.84e-11 GO:0004871 signal transducer activity
1.43 1.84e-11 GO:0060089 molecular transducer activity