Motif ID: HIF1A.p2

Z-value: 0.893


Transcription factors associated with HIF1A.p2:

Gene SymbolEntrez IDGene Name
HIF1A 3091 hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HIF1Achr14_+_612317950.292.7e-01Click!


Activity profile for motif HIF1A.p2.

activity profile for motif HIF1A.p2


Sorted Z-values histogram for motif HIF1A.p2

Sorted Z-values for motif HIF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HIF1A.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_191357680 1.437 NM_024529
CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chrX_-_13866366 1.217


chr7_+_156624392 1.146 NM_014671
UBE3C
ubiquitin protein ligase E3C
chrX_-_13866565 1.103 NM_001001994
GPM6B
glycoprotein M6B
chr1_+_191357788 1.052 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr7_+_156624424 1.030 UBE3C
ubiquitin protein ligase E3C
chr2_+_198072965 0.966 NM_002157
HSPE1
heat shock 10kDa protein 1 (chaperonin 10)
chr1_-_26105954 0.909 NM_203399
STMN1
stathmin 1
chr1_+_191357906 0.847 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_+_191357819 0.823 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_+_191357843 0.810 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_-_26105477 0.806 NM_001145454
NM_005563
STMN1

stathmin 1

chr8_-_54918369 0.707 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr2_+_198073257 0.701 HSPE1
heat shock 10kDa protein 1 (chaperonin 10)
chr3_-_180651874 0.664 GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr7_+_156624370 0.661 UBE3C
ubiquitin protein ligase E3C
chr8_-_54918389 0.656 NM_015941
NM_213619
ATP6V1H

ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

chr8_-_54918099 0.642 NM_213620
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr8_-_54918325 0.619 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chrX_-_148430250 0.605 LOC100131434
hypothetical LOC100131434

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
2.43 1.40e-02 GO:0050657 nucleic acid transport
2.43 1.40e-02 GO:0050658 RNA transport
2.43 1.40e-02 GO:0051236 establishment of RNA localization
2.35 2.81e-02 GO:0006403 RNA localization
2.33 8.23e-04 GO:0006913 nucleocytoplasmic transport
2.30 1.14e-03 GO:0051169 nuclear transport
2.24 4.08e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.92 2.96e-02 GO:0016567 protein ubiquitination
1.90 2.06e-02 GO:0032446 protein modification by small protein conjugation
1.78 4.10e-02 GO:0070647 protein modification by small protein conjugation or removal
1.55 4.31e-03 GO:0046907 intracellular transport
1.44 1.58e-03 GO:0051641 cellular localization
1.41 3.73e-02 GO:0051649 establishment of localization in cell
1.40 1.01e-07 GO:0044267 cellular protein metabolic process
1.37 5.08e-04 GO:0043412 macromolecule modification
1.37 6.60e-04 GO:0006464 protein modification process
1.34 2.84e-12 GO:0044260 cellular macromolecule metabolic process
1.29 1.59e-02 GO:0090304 nucleic acid metabolic process
1.28 3.74e-04 GO:0019538 protein metabolic process
1.27 6.29e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
2.18 1.73e-05 GO:0005635 nuclear envelope
2.17 8.85e-03 GO:0031965 nuclear membrane
1.88 1.97e-02 GO:0005813 centrosome
1.64 3.92e-05 GO:0031967 organelle envelope
1.62 5.46e-05 GO:0031975 envelope
1.57 2.14e-02 GO:0005730 nucleolus
1.42 5.32e-08 GO:0044428 nuclear part
1.42 2.36e-05 GO:0012505 endomembrane system
1.37 8.50e-06 GO:0005829 cytosol
1.36 1.01e-05 GO:0031090 organelle membrane
1.33 9.34e-04 GO:0031981 nuclear lumen
1.30 2.80e-04 GO:0031974 membrane-enclosed lumen
1.30 5.80e-04 GO:0043233 organelle lumen
1.30 6.32e-04 GO:0070013 intracellular organelle lumen
1.29 3.48e-14 GO:0005634 nucleus
1.28 1.05e-14 GO:0044444 cytoplasmic part
1.27 2.00e-11 GO:0044446 intracellular organelle part
1.26 1.01e-10 GO:0044422 organelle part
1.25 1.76e-24 GO:0043227 membrane-bounded organelle
1.25 1.86e-24 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.63 8.17e-06 GO:0003723 RNA binding
1.33 9.06e-05 GO:0000166 nucleotide binding
1.30 2.38e-02 GO:0016740 transferase activity
1.28 8.70e-06 GO:0003676 nucleic acid binding
1.21 1.58e-10 GO:0005515 protein binding
1.17 1.32e-03 GO:0003824 catalytic activity
1.09 3.09e-05 GO:0005488 binding