Motif ID: HIF1A.p2

Z-value: 0.893


Transcription factors associated with HIF1A.p2:

Gene SymbolEntrez IDGene Name
HIF1A 3091 hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HIF1Achr14_+_612317950.292.7e-01Click!


Activity profile for motif HIF1A.p2.

activity profile for motif HIF1A.p2


Sorted Z-values histogram for motif HIF1A.p2

Sorted Z-values for motif HIF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HIF1A.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_191357680 1.437 NM_024529
CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chrX_-_13866366 1.217


chr7_+_156624392 1.146 NM_014671
UBE3C
ubiquitin protein ligase E3C
chrX_-_13866565 1.103 NM_001001994
GPM6B
glycoprotein M6B
chr1_+_191357788 1.052 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr7_+_156624424 1.030 UBE3C
ubiquitin protein ligase E3C
chr2_+_198072965 0.966 NM_002157
HSPE1
heat shock 10kDa protein 1 (chaperonin 10)
chr1_-_26105954 0.909 NM_203399
STMN1
stathmin 1
chr1_+_191357906 0.847 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_+_191357819 0.823 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_+_191357843 0.810 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_-_26105477 0.806 NM_001145454
NM_005563
STMN1

stathmin 1

chr8_-_54918369 0.707 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr2_+_198073257 0.701 HSPE1
heat shock 10kDa protein 1 (chaperonin 10)
chr3_-_180651874 0.664 GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr7_+_156624370 0.661 UBE3C
ubiquitin protein ligase E3C
chr8_-_54918389 0.656 NM_015941
NM_213619
ATP6V1H

ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

chr8_-_54918099 0.642 NM_213620
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr8_-_54918325 0.619 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chrX_-_148430250 0.605 LOC100131434
hypothetical LOC100131434
chr22_+_38720881 0.598 NM_138435
FAM83F
family with sequence similarity 83, member F
chr11_+_13646806 0.568 FAR1
fatty acyl CoA reductase 1
chr11_+_13646727 0.554 NM_032228
FAR1
fatty acyl CoA reductase 1
chr17_-_64834780 0.550 NM_172232
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr1_-_173428455 0.547 NM_001162895
NM_014656
NM_001162893
NM_001162894
KIAA0040



KIAA0040



chr7_-_87343599 0.540 NM_018843
SLC25A40
solute carrier family 25, member 40
chr2_-_198072868 0.538 NM_002156
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr8_+_49083522 0.537 NM_003350
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr16_+_51722285 0.531 CHD9
chromodomain helicase DNA binding protein 9
chrX_+_16714452 0.529 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr12_+_129922510 0.507 NM_006325
RAN
RAN, member RAS oncogene family
chr2_+_198073358 0.506 HSPE1
heat shock 10kDa protein 1 (chaperonin 10)
chr3_+_37259684 0.505 NM_001172713
NM_002078
GOLGA4

golgin A4

chr6_-_153346283 0.499 NM_001142522
FBXO5
F-box protein 5
chr10_+_22649977 0.499 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr4_+_186554958 0.496 ANKRD37
ankyrin repeat domain 37
chr4_+_186554831 0.492 NM_181726
ANKRD37
ankyrin repeat domain 37
chr1_+_88922424 0.492 NM_006256
PKN2
protein kinase N2
chr1_-_29380969 0.492 SRSF4
serine/arginine-rich splicing factor 4
chr1_-_77921681 0.489 ZZZ3
zinc finger, ZZ-type containing 3
chr10_+_105716925 0.485 SLK
STE20-like kinase
chr2_+_32142083 0.480 NM_014946
NM_199436
SPAST

spastin

chr3_-_180652024 0.477 NM_021629
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr11_-_125730655 0.477 FLJ39051
hypothetical LOC399972
chr4_-_10068055 0.469 NM_053042
ZNF518B
zinc finger protein 518B
chr13_-_96444604 0.464 NM_080818
OXGR1
oxoglutarate (alpha-ketoglutarate) receptor 1
chr10_+_28861730 0.464


chr10_+_35455806 0.453 NM_001881
NM_182850
NM_182853
NM_183013
CREM



cAMP responsive element modulator



chr17_+_33706516 0.452 NM_032351
MRPL45
mitochondrial ribosomal protein L45
chr7_+_117611321 0.450 NM_016200
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr10_+_75580914 0.446 NM_006721
ADK
adenosine kinase
chr3_+_5204357 0.446 NM_014674
EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr5_+_170747312 0.444 NM_001037738
NM_002520
NM_199185
NPM1


nucleophosmin (nucleolar phosphoprotein B23, numatrin)


chrX_+_13581145 0.443 NM_152634
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr2_+_113119985 0.440 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr18_+_9904202 0.440 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr4_+_186554886 0.440 ANKRD37
ankyrin repeat domain 37
chr12_+_75681973 0.437 NM_015336
ZDHHC17
zinc finger, DHHC-type containing 17
chr4_-_166253374 0.436 TMEM192
transmembrane protein 192
chr3_+_5204430 0.434 EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr18_+_9903954 0.434 NM_003574
NM_194434
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr2_+_138975819 0.431 NM_001001664
SPOPL
speckle-type POZ protein-like
chr2_+_138975946 0.431


chr5_+_134122359 0.430 NM_014829
DDX46
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr18_+_9904249 0.424 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr11_+_18372493 0.419 NM_001135239
NM_001165415
NM_001165416
NM_005566
LDHA



lactate dehydrogenase A



chr3_+_143078202 0.417 ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr12_-_40918249 0.417 NM_001190977
YAF2
YY1 associated factor 2
chr2_-_6923215 0.415 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr1_-_37991160 0.413 EPHA10
EPH receptor A10
chr11_+_32808045 0.412 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr18_+_9904060 0.411 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr7_+_138695537 0.411 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr1_-_43606275 0.407 ELOVL1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr1_-_77920914 0.405 NM_015534
ZZZ3
zinc finger, ZZ-type containing 3
chr11_-_47620590 0.402 NM_014342
MTCH2
mitochondrial carrier homolog 2 (C. elegans)
chr8_-_81246215 0.400 NM_001025253
NM_005079
TPD52

tumor protein D52

chr18_+_9904032 0.395 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr5_+_176493488 0.393 NSD1
nuclear receptor binding SET domain protein 1
chrX_-_102452461 0.392 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr1_-_26105230 0.391 NM_203401
STMN1
stathmin 1
chr1_+_212843205 0.390 CENPF
centromere protein F, 350/400kDa (mitosin)
chr6_+_143423656 0.389 NM_016108
AIG1
androgen-induced 1
chrX_-_153952447 0.388 NM_001018024
NM_001018025
MTCP1NB
MTCP1
mature T-cell proliferation 1 neighbor
mature T-cell proliferation 1
chr3_+_32701663 0.388 NM_015442
CNOT10
CCR4-NOT transcription complex, subunit 10
chr7_-_95789204 0.387 NM_001160210
NM_014251
SLC25A13

solute carrier family 25, member 13 (citrin)

chr18_+_9904017 0.385 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr1_+_212843117 0.382 NM_016343
CENPF
centromere protein F, 350/400kDa (mitosin)
chr11_+_18372687 0.381 LDHA
lactate dehydrogenase A
chr4_-_83570318 0.381 NM_031372
HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr19_+_7608010 0.380 STXBP2
syntaxin binding protein 2
chr10_+_28861705 0.379 WAC
WW domain containing adaptor with coiled-coil
chr5_+_176493233 0.377 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr17_-_28228184 0.376 MYO1D
myosin ID
chr12_-_21702021 0.374 LDHB
lactate dehydrogenase B
chr12_+_105873803 0.374 C12orf23
chromosome 12 open reading frame 23
chr11_+_113776582 0.373 NM_016090
RBM7
RNA binding motif protein 7
chr11_+_18372689 0.373 LDHA
lactate dehydrogenase A
chr12_-_21702036 0.373 LDHB
lactate dehydrogenase B
chr18_+_9903992 0.373 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr11_+_18372708 0.372 LDHA
lactate dehydrogenase A
chr3_+_113534710 0.371 CD200
CD200 molecule
chr1_-_180840016 0.371 NM_002928
RGS16
regulator of G-protein signaling 16
chr1_+_181025494 0.369 NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr8_+_109525050 0.369 TTC35
tetratricopeptide repeat domain 35
chr3_+_44258381 0.365 NM_001145030
C3orf77
chromosome 3 open reading frame 77
chr7_-_104949787 0.363 NM_019042
PUS7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr3_+_157874898 0.362 NM_015508
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr1_+_172395170 0.362 NM_014857
RABGAP1L
RAB GTPase activating protein 1-like
chr10_+_22650145 0.360 BMI1
BMI1 polycomb ring finger oncogene
chr3_+_5204403 0.358 EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr9_-_76757555 0.358 NM_017998
C9orf40
chromosome 9 open reading frame 40
chr2_-_144806498 0.358 GTDC1
glycosyltransferase-like domain containing 1
chr12_-_40918417 0.358 NM_001190979
NM_001190980
NM_005748
YAF2


YY1 associated factor 2


chr2_-_144806508 0.356 NM_001164629
GTDC1
glycosyltransferase-like domain containing 1
chr4_+_321587 0.355 NM_003441
ZNF141
zinc finger protein 141
chr1_+_65386359 0.355 NM_013410
AK4
adenylate kinase 4
chr17_-_28228300 0.354 MYO1D
myosin ID
chr10_-_69505048 0.353 NM_015601
NM_022079
HERC4

hect domain and RLD 4

chr1_+_231816372 0.351 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr8_+_109525010 0.350 NM_014673
TTC35
tetratricopeptide repeat domain 35
chr6_+_143423723 0.350 AIG1
androgen-induced 1
chr7_+_87343673 0.350 DBF4
DBF4 homolog (S. cerevisiae)
chr11_-_8942577 0.349 TMEM9B
TMEM9 domain family, member B
chr12_-_21702000 0.349 LDHB
lactate dehydrogenase B
chr6_+_16237300 0.348 MYLIP
myosin regulatory light chain interacting protein
chr12_-_21702046 0.347 NM_002300
LDHB
lactate dehydrogenase B
chr11_-_107234733 0.344 SLC35F2
solute carrier family 35, member F2
chr8_+_98725505 0.343 NM_178812
MTDH
metadherin
chr5_-_142763418 0.342 NM_000176
NM_001020825
NM_001024094
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr18_+_9904000 0.341 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr19_+_7608015 0.340 STXBP2
syntaxin binding protein 2
chrX_+_64804235 0.339 NM_002444
MSN
moesin
chr5_-_81609910 0.338 RPS23
ribosomal protein S23
chr15_-_57013058 0.335 SLTM
SAFB-like, transcription modulator
chr3_+_184898234 0.335 NM_018023
YEATS2
YEATS domain containing 2
chr11_-_113776262 0.334 NM_019021
C11orf71
chromosome 11 open reading frame 71
chr8_-_97342971 0.334 NM_015942
MTERFD1
MTERF domain containing 1
chr11_-_8942531 0.333 NM_020644
TMEM9B
TMEM9 domain family, member B
chr8_+_6553543 0.333 AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr5_+_49998677 0.333 PARP8
poly (ADP-ribose) polymerase family, member 8
chr7_+_44802798 0.332 PPIA
peptidylprolyl isomerase A (cyclophilin A)
chr1_+_54184595 0.331 NM_052940
LRRC42
leucine rich repeat containing 42
chr2_+_190981257 0.331 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr3_-_114221174 0.331 C3orf17
chromosome 3 open reading frame 17
chr8_-_102287044 0.330 NM_001042511
ZNF706
zinc finger protein 706
chr12_+_75682016 0.330 ZDHHC17
zinc finger, DHHC-type containing 17
chr1_-_245401874 0.329 NM_003431
ZNF124
zinc finger protein 124
chr3_+_5204484 0.329 EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr11_+_85633908 0.329 EED
embryonic ectoderm development
chr10_+_105716836 0.328 SLK
STE20-like kinase
chr12_+_49444509 0.327 ATF1
activating transcription factor 1
chr13_+_97426713 0.327 IPO5
importin 5
chr2_-_112729072 0.326 NM_032494
ZC3H8
zinc finger CCCH-type containing 8
chr3_-_15875932 0.325 NM_015199
ANKRD28
ankyrin repeat domain 28
chr8_+_95722448 0.324 ESRP1
epithelial splicing regulatory protein 1
chr19_+_7608020 0.324 STXBP2
syntaxin binding protein 2
chrX_+_24077649 0.324 NM_001178086
NM_001178095
NM_001178084
NM_001178085
NM_003410
ZFX




zinc finger protein, X-linked




chr2_-_213724577 0.323 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_-_43606254 0.323 ELOVL1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr12_+_105873669 0.323 NM_152261
C12orf23
chromosome 12 open reading frame 23
chr10_-_121346517 0.322 NM_001033925
NM_003252
TIAL1

TIA1 cytotoxic granule-associated RNA binding protein-like 1

chr5_+_110587546 0.322 NM_001744
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr7_-_87343389 0.321 SLC25A40
solute carrier family 25, member 40
chr5_+_89890366 0.321 NM_032119
GPR98
G protein-coupled receptor 98
chr1_-_181871416 0.318 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr1_+_117253882 0.318 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr21_+_25856311 0.317 MIR155HG
MIR155 host gene (non-protein coding)
chr3_+_171558143 0.316 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr8_+_75050930 0.315 NM_001040613
NM_017866
TMEM70

transmembrane protein 70

chr10_+_70553936 0.313 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chrX_+_11686198 0.313 NM_078628
NM_078629
MSL3

male-specific lethal 3 homolog (Drosophila)

chr19_+_7607976 0.313 NM_001127396
NM_006949
STXBP2

syntaxin binding protein 2

chr7_-_6713066 0.312 NM_006956
NM_016265
ZNF12

zinc finger protein 12

chr3_-_157755603 0.311 NM_007107
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr6_-_97452481 0.309 NM_014165
NDUFAF4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chr6_+_87921980 0.308 NM_015021
ZNF292
zinc finger protein 292
chr2_+_28828112 0.306 NM_206876
NM_002709
PPP1CB

protein phosphatase 1, catalytic subunit, beta isozyme

chr1_-_181871473 0.306 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr12_+_123023521 0.306 NM_152437
ZNF664
zinc finger protein 664
chr2_+_187059277 0.305 ZC3H15
zinc finger CCCH-type containing 15
chr15_-_76700174 0.305 CHRNA3
cholinergic receptor, nicotinic, alpha 3
chr1_-_181871490 0.304 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr2_+_173129040 0.304 PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr12_-_91847042 0.304 EEA1
early endosome antigen 1
chr3_-_81893486 0.304 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr15_-_57013092 0.303 NM_001013843
NM_024755
SLTM

SAFB-like, transcription modulator

chr6_-_86360279 0.302 NM_020468
NM_153816
SNX14

sorting nexin 14

chr14_-_64040072 0.301 NM_006977
ZBTB25
zinc finger and BTB domain containing 25
chr1_+_172395277 0.301 RABGAP1L
RAB GTPase activating protein 1-like
chr15_+_61356801 0.300 NM_001145646
NM_031301
APH1B

anterior pharynx defective 1 homolog B (C. elegans)

chr3_+_180523374 0.299 ZNF639
zinc finger protein 639
chr12_+_129922589 0.298 RAN
RAN, member RAS oncogene family
chr6_+_43846735 0.294 VEGFA
vascular endothelial growth factor A
chr1_-_35957030 0.294 C1orf216
chromosome 1 open reading frame 216
chr11_+_66268740 0.293 NM_024650
C11orf80
chromosome 11 open reading frame 80
chr7_+_106472243 0.293 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chrX_+_24077782 0.292 ZFX
zinc finger protein, X-linked
chr7_+_138695209 0.291 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr3_-_57088332 0.289 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 2.84e-12 GO:0044260 cellular macromolecule metabolic process
1.26 1.52e-11 GO:0044237 cellular metabolic process
1.26 4.09e-08 GO:0043170 macromolecule metabolic process
1.40 1.01e-07 GO:0044267 cellular protein metabolic process
1.21 2.48e-07 GO:0044238 primary metabolic process
1.18 2.01e-06 GO:0008152 metabolic process
1.09 3.25e-04 GO:0009987 cellular process
1.28 3.74e-04 GO:0019538 protein metabolic process
1.37 5.08e-04 GO:0043412 macromolecule modification
1.37 6.60e-04 GO:0006464 protein modification process
2.33 8.23e-04 GO:0006913 nucleocytoplasmic transport
2.30 1.14e-03 GO:0051169 nuclear transport
1.44 1.58e-03 GO:0051641 cellular localization
1.55 4.31e-03 GO:0046907 intracellular transport
1.27 6.29e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 1.30e-02 GO:0034641 cellular nitrogen compound metabolic process
2.43 1.40e-02 GO:0050657 nucleic acid transport
2.43 1.40e-02 GO:0050658 RNA transport
2.43 1.40e-02 GO:0051236 establishment of RNA localization
1.29 1.59e-02 GO:0090304 nucleic acid metabolic process
1.23 1.68e-02 GO:0006807 nitrogen compound metabolic process
1.90 2.06e-02 GO:0032446 protein modification by small protein conjugation
2.35 2.81e-02 GO:0006403 RNA localization
1.92 2.96e-02 GO:0016567 protein ubiquitination
1.41 3.73e-02 GO:0051649 establishment of localization in cell
2.24 4.08e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.78 4.10e-02 GO:0070647 protein modification by small protein conjugation or removal

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.22 7.07e-37 GO:0044424 intracellular part
1.21 2.77e-35 GO:0005622 intracellular
1.25 1.76e-24 GO:0043227 membrane-bounded organelle
1.25 1.86e-24 GO:0043231 intracellular membrane-bounded organelle
1.22 9.11e-23 GO:0043226 organelle
1.21 2.01e-22 GO:0043229 intracellular organelle
1.25 5.28e-22 GO:0005737 cytoplasm
1.28 1.05e-14 GO:0044444 cytoplasmic part
1.29 3.48e-14 GO:0005634 nucleus
1.27 2.00e-11 GO:0044446 intracellular organelle part
1.07 5.65e-11 GO:0044464 cell part
1.07 5.95e-11 GO:0005623 cell
1.26 1.01e-10 GO:0044422 organelle part
1.42 5.32e-08 GO:0044428 nuclear part
1.37 8.50e-06 GO:0005829 cytosol
1.36 1.01e-05 GO:0031090 organelle membrane
2.18 1.73e-05 GO:0005635 nuclear envelope
1.42 2.36e-05 GO:0012505 endomembrane system
1.64 3.92e-05 GO:0031967 organelle envelope
1.62 5.46e-05 GO:0031975 envelope
1.30 2.80e-04 GO:0031974 membrane-enclosed lumen
1.30 5.80e-04 GO:0043233 organelle lumen
1.30 6.32e-04 GO:0070013 intracellular organelle lumen
1.33 9.34e-04 GO:0031981 nuclear lumen
2.17 8.85e-03 GO:0031965 nuclear membrane
1.88 1.97e-02 GO:0005813 centrosome
1.57 2.14e-02 GO:0005730 nucleolus
1.19 2.25e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 1.58e-10 GO:0005515 protein binding
1.63 8.17e-06 GO:0003723 RNA binding
1.28 8.70e-06 GO:0003676 nucleic acid binding
1.09 3.09e-05 GO:0005488 binding
1.33 9.06e-05 GO:0000166 nucleotide binding
1.17 1.32e-03 GO:0003824 catalytic activity
1.30 2.38e-02 GO:0016740 transferase activity