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Motif ID: GLI1..3.p2

Z-value: 1.690

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_2461500	2.254	NM_006181	NTN3	netrin 3
chr11_-_118055564	2.011	NM_007180	TREH	trehalase (brush-border membrane glycoprotein)
chr9_-_112840064	1.928	NM_001401 NM_057159	LPAR1	lysophosphatidic acid receptor 1
chr5_-_156935283	1.712
chr5_-_168660293	1.683	NM_003062	SLIT3	slit homolog 3 (Drosophila)
chr12_-_113330574	1.675	NM_000192 NM_080717	TBX5	T-box 5
chr16_+_85169615	1.659	NM_005250	FOXL1	forkhead box L1
chr19_-_6061561	1.656	NM_000635 NM_134433	RFX2	regulatory factor X, 2 (influences HLA class II expression)
chr5_+_122452739	1.563	NM_001136239	PRDM6	PR domain containing 6
chr16_+_85158357	1.539	NM_005251	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr16_-_1999796	1.535		ZNF598	zinc finger protein 598
chr16_+_85101605	1.477	NM_001451	FOXF1	forkhead box F1
chr17_+_58058783	1.446		MRC2	mannose receptor, C type 2
chr9_+_18464090	1.431	NM_001040272 NM_052866	ADAMTSL1	ADAMTS-like 1
chr4_+_72271218	1.424	NM_001098484 NM_001134742	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr22_-_26527469	1.403	NM_002430	MN1	meningioma (disrupted in balanced translocation) 1
chr1_-_32036802	1.399		SPOCD1	SPOC domain containing 1
chr5_-_156935317	1.387	NM_033274	ADAM19	ADAM metallopeptidase domain 19
chr6_-_166960690	1.385	NM_021135	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr20_+_1194959	1.354	NM_014723	SNPH	syntaphilin
chr12_-_6668680	1.351		ZNF384	zinc finger protein 384
chr16_+_31390567	1.317	NM_001042454 NM_001164719	TGFB1I1	transforming growth factor beta 1 induced transcript 1
chr8_+_120497732	1.306	NM_002514	NOV	nephroblastoma overexpressed gene
chr22_-_42589543	1.285	NM_014351	SULT4A1	sulfotransferase family 4A, member 1
chr15_-_38417564	1.277		C15orf52	chromosome 15 open reading frame 52
chr7_-_80386602	1.277	NM_006379	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_-_100262971	1.251	NM_004444	EPHB4	EPH receptor B4
chr12_-_6668880	1.229	NM_001039917 NM_001039919 NM_001039920 NM_001135734	ZNF384	zinc finger protein 384
chr7_-_80386258	1.208		SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_-_105208634	1.206	NM_001001412	CALHM1	calcium homeostasis modulator 1
chr17_+_45703765	1.199	NM_001168215	TMEM92	transmembrane protein 92
chr13_-_109236897	1.165	NM_003749	IRS2	insulin receptor substrate 2
chr16_+_85101734	1.157		FOXF1	forkhead box F1
chr12_-_6668787	1.138	NM_001039918 NM_133476	ZNF384	zinc finger protein 384
chr17_+_45617676	1.130
chr19_+_10900419	1.112	NM_138358	C19orf52	chromosome 19 open reading frame 52
chr19_-_54835162	1.107	NM_006270	RRAS	related RAS viral (r-ras) oncogene homolog
chr6_-_166960649	1.106		RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr11_-_3104413	1.103		OSBPL5	oxysterol binding protein-like 5
chr3_+_50272648	1.090
chr1_-_32054164	1.088	NM_144569	SPOCD1	SPOC domain containing 1
chr1_-_39877928	1.085	NM_014571	HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr19_+_16296632	1.085	NM_016270	KLF2	Kruppel-like factor 2 (lung)
chrX_+_49013424	1.084		PPP1R3F	protein phosphatase 1, regulatory (inhibitor) subunit 3F
chrX_-_53367246	1.082	NM_001111125	IQSEC2	IQ motif and Sec7 domain 2
chr10_-_46593923	1.079	NM_001040084 NM_001098845	ANXA8L2 LOC653110 ANXA8 ANXA8L1	annexin A8-like 2 hypothetical LOC653110 annexin A8 annexin A8-like 1
chr1_-_39877883	1.074		HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr5_+_175725050	1.063	NM_173664	ARL10	ADP-ribosylation factor-like 10
chr1_-_16411690	1.052	NM_153213	ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19
chr4_+_134289893	1.046	NM_020815 NM_032961	PCDH10	protocadherin 10
chr7_+_43118721	1.036	NM_015052	HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr16_-_1999760	1.029	NM_178167	ZNF598	zinc finger protein 598
chr19_-_55763091	1.028	NM_001080457	LRRC4B	leucine rich repeat containing 4B
chr12_-_51132129	1.028	NM_005555	KRT6B	keratin 6B
chr9_+_108665168	1.012	NM_021224	ZNF462	zinc finger protein 462
chr10_+_104493701	1.012		C10orf26	chromosome 10 open reading frame 26
chr1_+_99502655	0.991		LPPR4	lipid phosphate phosphatase-related protein type 4
chr8_+_32525269	0.989	NM_001160002 NM_001160004 NM_001160005 NM_001160007 NM_001160008 NM_004495 NM_013956 NM_013957 NM_013958 NM_013960 NM_013964	NRG1	neuregulin 1
chr9_+_115151632	0.978	NM_017688	BSPRY	B-box and SPRY domain containing
chr18_-_42804531	0.976	NM_145653	TCEB3C	transcription elongation factor B polypeptide 3C (elongin A3)
chr2_+_220200530	0.965	NM_005070 NM_201574	SLC4A3	solute carrier family 4, anion exchanger, member 3
chr4_-_957269	0.965		DGKQ	diacylglycerol kinase, theta 110kDa
chr19_+_10900502	0.963		C19orf52	chromosome 19 open reading frame 52
chr11_+_58980986	0.956	NM_001004708	OR4D6	olfactory receptor, family 4, subfamily D, member 6
chr1_+_200358594	0.954	NM_004767	GPR37L1	G protein-coupled receptor 37 like 1
chr10_-_105202012	0.949		CALHM2	calcium homeostasis modulator 2
chr17_-_7078446	0.945	NM_004422	DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr1_-_169888373	0.944	NM_000261	MYOC	myocilin, trabecular meshwork inducible glucocorticoid response
chr16_+_87021379	0.941	NM_001127464	ZNF469	zinc finger protein 469
chr1_+_151209751	0.941	NM_173080	SPRR4	small proline-rich protein 4
chr19_+_627346	0.934	NM_005860	FSTL3	follistatin-like 3 (secreted glycoprotein)
chr19_-_53516962	0.922		CCDC114	coiled-coil domain containing 114
chr6_-_166960496	0.919		RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_+_83130220	0.910		TPBG	trophoblast glycoprotein
chr17_-_34607257	0.905	NM_000723 NM_199247 NM_199248	CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr19_+_43502591	0.904		KCNK6	potassium channel, subfamily K, member 6
chr19_+_43502380	0.903		KCNK6	potassium channel, subfamily K, member 6
chr19_+_43502301	0.902	NM_004823	KCNK6	potassium channel, subfamily K, member 6
chr17_+_73738985	0.902	NM_001145529	TMEM235	transmembrane protein 235
chr19_-_15436333	0.893	NM_022904	RASAL3	RAS protein activator like 3
chr4_-_13155135	0.891	NM_001189	NKX3-2	NK3 homeobox 2
chr6_-_32892705	0.888	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chr22_+_35777561	0.882	NM_024681	KCTD17	potassium channel tetramerisation domain containing 17
chr17_-_28644118	0.881	NM_183377	ACCN1	amiloride-sensitive cation channel 1, neuronal
chr1_+_148090804	0.876	NM_021059 NM_001005464	HIST2H3C HIST2H3A	histone cluster 2, H3c histone cluster 2, H3a
chr6_-_34209250	0.876	NM_000841	GRM4	glutamate receptor, metabotropic 4
chr17_-_15185623	0.872	NM_031898	TEKT3	tektin 3
chr11_+_112763722	0.871	NM_178510	ANKK1	ankyrin repeat and kinase domain containing 1
chr11_+_2355119	0.870	NM_004356	CD81	CD81 molecule
chr11_-_65841077	0.862	NM_020404	CD248	CD248 molecule, endosialin
chr19_-_11477689	0.859	NM_138783	ZNF653	zinc finger protein 653
chr8_-_22044463	0.855	NM_005144 NM_018411	HR	hairless homolog (mouse)
chr18_-_42804291	0.852	NM_001100817	TCEB3C TCEB3CL	transcription elongation factor B polypeptide 3C (elongin A3) transcription elongation factor B polypeptide 3C-like
chr10_+_47875229	0.850	NM_001040084 NM_001098845	ANXA8L2 ANXA8 ANXA8L1	annexin A8-like 2 annexin A8 annexin A8-like 1
chr12_-_3732614	0.849	NM_001144958 NM_001144959 NM_032680	EFCAB4B	EF-hand calcium binding domain 4B
chr10_+_47216925	0.848	NM_001630	ANXA8L2 ANXA8	annexin A8-like 2 annexin A8
chr15_-_40236061	0.848	NM_213600	PLA2G4F	phospholipase A2, group IVF
chrX_-_47941142	0.847	NM_021015 NM_175723	SSX5	synovial sarcoma, X breakpoint 5
chr12_-_3732478	0.846		EFCAB4B	EF-hand calcium binding domain 4B
chr13_+_43845977	0.846	NM_001010897	SERP2	stress-associated endoplasmic reticulum protein family member 2
chr4_-_90977149	0.844	NM_001146054 NM_007308 NM_000345	SNCA	synuclein, alpha (non A4 component of amyloid precursor)
chr6_+_83129641	0.843	NM_006670	TPBG	trophoblast glycoprotein
chr19_-_13808101	0.843		LOC284454	hypothetical LOC284454
chr5_-_37875538	0.843	NM_000514	GDNF	glial cell derived neurotrophic factor
chr19_+_1334877	0.837	NM_024407	NDUFS7	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr9_-_130980359	0.835	NM_203434	IER5L	immediate early response 5-like
chr2_+_241023703	0.833	NM_002081	GPC1	glypican 1
chr15_+_39032927	0.828	NM_001142776 NM_024111	CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)
chr15_+_37660568	0.828	NM_003246	THBS1	thrombospondin 1
chr22_-_49050847	0.828	NM_002751	MAPK11	mitogen-activated protein kinase 11
chr1_-_1300680	0.827	NM_017900	AURKAIP1	aurora kinase A interacting protein 1
chr10_+_104493714	0.826	NM_001083913	C10orf26	chromosome 10 open reading frame 26
chr19_+_482737	0.825		CDC34	cell division cycle 34 homolog (S. cerevisiae)
chr18_-_42798364	0.825	NM_001100817	TCEB3C TCEB3CL	transcription elongation factor B polypeptide 3C (elongin A3) transcription elongation factor B polypeptide 3C-like
chr1_-_150653351	0.820	NM_016190	CRNN	cornulin
chr3_-_173648896	0.819	NM_004122 NM_198407	GHSR	growth hormone secretagogue receptor
chr14_+_105012106	0.813	NM_001312	CRIP2	cysteine-rich protein 2
chr9_+_130909926	0.801
chr1_-_1300416	0.795	NM_001127230 NM_001127229	AURKAIP1	aurora kinase A interacting protein 1
chr5_-_168204430	0.794
chr7_-_41709191	0.791	NM_002192	INHBA	inhibin, beta A
chr19_-_45611110	0.791	NM_020956 NM_181882	PRX	periaxin
chr19_+_2240996	0.789
chr2_-_175578156	0.788	NM_001025201 NM_001822	CHN1	chimerin (chimaerin) 1
chr19_-_10900086	0.784	NM_024029	YIPF2	Yip1 domain family, member 2
chr19_+_43502360	0.783		KCNK6	potassium channel, subfamily K, member 6
chr5_-_149515331	0.781		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr1_-_45081190	0.781	NM_001166292 NM_003738	PTCH2	patched 2
chrX_+_64804235	0.772	NM_002444	MSN	moesin
chr1_+_17507276	0.772	NM_012387	PADI4	peptidyl arginine deiminase, type IV
chr19_+_13124889	0.767		IER2	immediate early response 2
chr10_-_133995323	0.763		STK32C	serine/threonine kinase 32C
chr11_+_76455574	0.762	NM_004055	CAPN5	calpain 5
chr1_+_1256585	0.762	NM_152228	TAS1R3	taste receptor, type 1, member 3
chr17_-_1366520	0.761		INPP5K	inositol polyphosphate-5-phosphatase K
chr9_-_34448477	0.758	NM_001184940 NM_001184941 NM_001184942 NM_001184943 NM_001184944 NM_001184945 NM_147202	C9orf25	chromosome 9 open reading frame 25
chr15_+_72209039	0.757	NM_001130137	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr16_-_31390926	0.756
chr16_+_82782223	0.755	NM_001145400 NM_139174	ADAD2	adenosine deaminase domain containing 2
chr11_-_89181390	0.753	NM_020358	TRIM49	tripartite motif containing 49
chr22_-_17546234	0.751		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr4_-_140696740	0.749	NM_030648	SETD7	SET domain containing (lysine methyltransferase) 7
chr3_-_197120276	0.749	NM_005781	TNK2	tyrosine kinase, non-receptor, 2
chr11_-_61441536	0.747	NM_013401	RAB3IL1	RAB3A interacting protein (rabin3)-like 1
chr9_+_134027154	0.745	NM_032536	NTNG2	netrin G2
chr9_-_134743984	0.745	NM_152572	AK8	adenylate kinase 8
chr18_-_42810446	0.745	NM_145653	TCEB3C	transcription elongation factor B polypeptide 3C (elongin A3)
chr3_-_62835601	0.744
chr11_-_66877519	0.743	NM_021173	POLD4	polymerase (DNA-directed), delta 4
chr19_+_16296734	0.742		KLF2	Kruppel-like factor 2 (lung)
chr16_+_48865521	0.736		ADCY7	adenylate cyclase 7
chrX_-_30237403	0.734	NM_000475	NR0B1	nuclear receptor subfamily 0, group B, member 1
chr6_+_3697328	0.733
chr1_+_34993234	0.730	NM_005268	GJB5	gap junction protein, beta 5, 31.1kDa
chr14_+_28305922	0.728	NM_005249	FOXG1	forkhead box G1
chr11_+_65815911	0.726		TMEM151A	transmembrane protein 151A
chr20_-_60228665	0.725	NM_007232	HRH3	histamine receptor H3
chr2_+_109112428	0.721	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr7_-_6557591	0.719	NM_001145118	GRID2IP	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
chr7_+_2525922	0.717	NM_001040167 NM_001040168	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_232107170	0.713	NM_173508	SLC35F3	solute carrier family 35, member F3
chr15_+_76419680	0.712	NM_004378	CRABP1	cellular retinoic acid binding protein 1
chr19_-_11477395	0.711		ZNF653	zinc finger protein 653
chr7_-_44992729	0.710		C7orf40	chromosome 7 open reading frame 40
chr17_-_27210330	0.710	NM_018405	C17orf79	chromosome 17 open reading frame 79
chr22_-_17545872	0.708		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chrX_+_64804259	0.705		MSN	moesin
chr17_+_7283412	0.704	NM_004112	FGF11	fibroblast growth factor 11
chr19_+_43572679	0.703	NM_001039616 NM_001042522	SPRED3	sprouty-related, EVH1 domain containing 3
chr5_-_169340321	0.700	NM_001129891	FAM196B	family with sequence similarity 196, member B
chr11_+_65815940	0.697	NM_153266	TMEM151A	transmembrane protein 151A
chr1_+_43539239	0.696	NM_005424	TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr6_-_168222645	0.694	NM_024919	FRMD1	FERM domain containing 1
chr10_+_106103503	0.694	NM_001008723	CCDC147	coiled-coil domain containing 147
chr8_+_124264054	0.685		FAM83A	family with sequence similarity 83, member A
chr19_-_45888259	0.685	NM_004756	NUMBL	numb homolog (Drosophila)-like
chrX_+_106955737	0.685	NM_012216 NM_052817	MID2	midline 2
chr19_-_16514232	0.683		CHERP	calcium homeostasis endoplasmic reticulum protein
chr7_-_150515851	0.682	NM_080871	ASB10	ankyrin repeat and SOCS box containing 10
chr6_-_26135458	0.681	NM_003544	HIST1H4B	histone cluster 1, H4b
chr11_-_60880799	0.678	NM_001161452	CYBASC3	cytochrome b, ascorbate dependent 3
chr18_+_75354312	0.675		NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr1_-_209818342	0.675		SLC30A1	solute carrier family 30 (zinc transporter), member 1
chr5_+_167889123	0.674
chr7_-_27191287	0.673	NM_005523	HOXA11	homeobox A11
chr15_+_72208751	0.673	NM_001130136	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chrX_+_64804318	0.667		MSN	moesin
chr11_+_66381451	0.665	NM_024036	LRFN4	leucine rich repeat and fibronectin type III domain containing 4
chr8_-_41774296	0.664	NM_000037 NM_020475 NM_020476 NM_020477	ANK1	ankyrin 1, erythrocytic
chr6_-_29708938	0.661	NM_001470 NM_021904	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr1_+_19842309	0.659	NM_182744	NBL1	neuroblastoma, suppression of tumorigenicity 1
chr9_-_130980302	0.657		IER5L	immediate early response 5-like
chr1_+_149309703	0.656	NM_144618	GABPB2	GA binding protein transcription factor, beta subunit 2
chr1_-_149385556	0.655	NM_001178061 NM_001178062 NM_030913	SEMA6C	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr22_+_18388656	0.654		C22orf25	chromosome 22 open reading frame 25
chr6_-_29708838	0.653		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr1_+_151147646	0.653	NM_005547	IVL	involucrin
chr14_-_104515738	0.652	NM_138420	AHNAK2	AHNAK nucleoprotein 2
chr7_-_150411504	0.652	NM_001136044	TMUB1	transmembrane and ubiquitin-like domain containing 1
chr16_-_2258067	0.650		RNPS1	RNA binding protein S1, serine-rich domain

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.43	1.98e-07	GO:0023051	regulation of signaling
1.30	3.06e-07	GO:0048731	system development
1.42	2.71e-06	GO:0009653	anatomical structure morphogenesis
1.26	4.29e-06	GO:0048856	anatomical structure development
1.39	3.49e-05	GO:0007399	nervous system development
1.32	4.57e-05	GO:0048869	cellular developmental process
1.23	5.42e-05	GO:0007275	multicellular organismal development
1.39	6.43e-05	GO:0009966	regulation of signal transduction
1.32	6.60e-05	GO:0030154	cell differentiation
1.33	7.57e-05	GO:0048583	regulation of response to stimulus
1.22	8.15e-05	GO:0032502	developmental process
1.17	2.20e-04	GO:0032501	multicellular organismal process
1.44	2.80e-04	GO:0010646	regulation of cell communication
1.48	7.33e-04	GO:0048699	generation of neurons
1.20	1.30e-03	GO:0023052	signaling
1.44	1.73e-03	GO:0022008	neurogenesis
2.12	2.14e-03	GO:0006813	potassium ion transport
1.51	2.94e-03	GO:0010628	positive regulation of gene expression
1.53	3.06e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.40	4.53e-03	GO:0007154	cell communication
1.59	7.61e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.45	7.91e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.62	1.26e-02	GO:0007409	axonogenesis
1.44	1.67e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47	2.32e-02	GO:0051254	positive regulation of RNA metabolic process
1.26	2.49e-02	GO:0048513	organ development
1.11	2.69e-02	GO:0050794	regulation of cellular process
1.44	2.74e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.40	2.99e-02	GO:0040011	locomotion
1.58	2.99e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
1.57	3.37e-02	GO:0048812	neuron projection morphogenesis
1.53	3.41e-02	GO:0000904	cell morphogenesis involved in differentiation
1.45	3.70e-02	GO:0030182	neuron differentiation
1.54	3.71e-02	GO:0031175	neuron projection development
1.38	4.96e-02	GO:0048468	cell development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.32	7.29e-07	GO:0044459	plasma membrane part
1.20	5.58e-06	GO:0071944	cell periphery
1.20	7.15e-06	GO:0005886	plasma membrane
1.34	1.19e-03	GO:0031226	intrinsic to plasma membrane
1.34	1.48e-03	GO:0005887	integral to plasma membrane
2.06	3.50e-03	GO:0034703	cation channel complex
1.52	2.94e-02	GO:0043005	neuron projection
2.19	3.11e-02	GO:0008076	voltage-gated potassium channel complex
2.19	3.11e-02	GO:0034705	potassium channel complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.50	5.30e-04	GO:0043565	sequence-specific DNA binding
1.80	9.73e-04	GO:0005261	cation channel activity
2.21	1.02e-03	GO:0005267	potassium channel activity
2.01	9.15e-03	GO:0022843	voltage-gated cation channel activity
1.70	2.14e-02	GO:0005096	GTPase activator activity
1.34	2.41e-02	GO:0001071	nucleic acid binding transcription factor activity
1.34	2.41e-02	GO:0003700	sequence-specific DNA binding transcription factor activity