Motif ID: RXR{A,B,G}.p2

Z-value: 2.392


Transcription factors associated with RXR{A,B,G}.p2:

Gene SymbolEntrez IDGene Name
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RXRBchr6_-_332761410.712.2e-03Click!
RXRAchr9_+_1363581340.581.9e-02Click!
RXRGchr1_-_1636809410.049.0e-01Click!


Activity profile for motif RXR{A,B,G}.p2.

activity profile for motif RXR{A,B,G}.p2


Sorted Z-values histogram for motif RXR{A,B,G}.p2

Sorted Z-values for motif RXR{A,B,G}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXR{A,B,G}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_44429748 2.557 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr19_-_1125257 2.421 SBNO2
strawberry notch homolog 2 (Drosophila)
chr7_+_2638108 2.403 NM_025250
TTYH3
tweety homolog 3 (Drosophila)
chr22_+_18081968 2.160 NM_002688
SEPT5
septin 5
chr7_+_100156358 2.106 NM_000799
EPO
erythropoietin
chr17_+_76988134 2.070 NM_001080519
BAHCC1
BAH domain and coiled-coil containing 1
chr12_+_50686990 2.070 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr19_+_55046229 1.980 PTOV1
prostate tumor overexpressed 1
chr19_+_55046088 1.977 NM_017432
PTOV1
prostate tumor overexpressed 1
chr19_-_1125201 1.963


chr7_+_2638156 1.954 TTYH3
tweety homolog 3 (Drosophila)
chr17_+_78630793 1.949 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr16_-_69277355 1.844 NM_138383
MTSS1L
metastasis suppressor 1-like
chr17_+_78286687 1.719 NM_022158
FN3K
fructosamine 3 kinase
chr19_-_1125263 1.719 NM_014963
SBNO2
strawberry notch homolog 2 (Drosophila)
chr19_+_18391211 1.715 NM_001009998
NM_032627
SSBP4

single stranded DNA binding protein 4

chr17_+_56832255 1.651 TBX2
T-box 2
chr6_-_2916786 1.648 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr17_+_56831951 1.595 NM_005994
TBX2
T-box 2
chr17_-_74433048 1.510 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr19_-_6375536 1.482 KHSRP
KH-type splicing regulatory protein
chr6_-_2916280 1.469 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr19_-_772913 1.432 NM_024888
LPPR3
lipid phosphate phosphatase-related protein type 3
chr5_+_92946348 1.419 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr9_-_101621964 1.401


chr14_-_88090641 1.386 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr19_+_18391423 1.371


chr19_-_61324456 1.368 NM_001002836
ZNF787
zinc finger protein 787
chr17_-_36475652 1.354 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr2_+_27155197 1.325 EMILIN1
elastin microfibril interfacer 1
chr11_+_440260 1.293 NM_030783
PTDSS2
phosphatidylserine synthase 2
chr11_+_65162114 1.290 NM_006747
SIPA1
signal-induced proliferation-associated 1
chr20_+_36663865 1.284 NM_001164431
ARHGAP40
Rho GTPase activating protein 40
chr15_+_39008822 1.281 NM_019074
DLL4
delta-like 4 (Drosophila)
chr4_+_995609 1.265 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr10_-_80875097 1.259 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr20_+_48032918 1.222 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr3_+_51680261 1.220 NM_001129884
NM_015926
TEX264

testis expressed 264

chr17_-_40923907 1.220 NM_014798
PLEKHM1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr6_-_132314004 1.208 NM_001901
CTGF
connective tissue growth factor
chr4_+_995395 1.202 FGFRL1
fibroblast growth factor receptor-like 1
chr19_-_772966 1.192 LPPR3
lipid phosphate phosphatase-related protein type 3
chrX_-_48929685 1.176 NM_006150
PRICKLE3
prickle homolog 3 (Drosophila)
chr16_+_658158 1.166 RHOT2
ras homolog gene family, member T2
chr12_+_55808514 1.160 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr11_+_10283171 1.151 NM_001124
ADM
adrenomedullin
chr17_-_39796649 1.146 NM_198475
FAM171A2
family with sequence similarity 171, member A2
chr6_-_33374275 1.145 RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr20_-_25514137 1.138 NM_025176
NINL
ninein-like
chr16_+_30815428 1.132 NM_001142544
NM_001330
CTF1

cardiotrophin 1

chr9_+_130224950 1.119 CERCAM
cerebral endothelial cell adhesion molecule
chr14_-_103058568 1.114 CKB
creatine kinase, brain
chr17_+_37222731 1.106 FKBP10
FK506 binding protein 10, 65 kDa
chr4_-_658035 1.101 NM_007100
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr11_+_440346 1.092 PTDSS2
phosphatidylserine synthase 2
chr11_-_86343737 1.088 FZD4
frizzled homolog 4 (Drosophila)
chr19_+_17691302 1.075 NM_018174
MAP1S
microtubule-associated protein 1S
chr5_+_149845503 1.073 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr2_-_75641587 1.071 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr19_-_6375804 1.057 KHSRP
KH-type splicing regulatory protein
chr11_+_117906965 1.035 NM_001144034
NM_001144035
NM_001144036
NM_001144037
NM_001144038
NM_032780
TMEM25





transmembrane protein 25





chr9_-_139128979 1.028 DPP7
dipeptidyl-peptidase 7
chr12_-_50502474 1.026 NM_001013690
FIGNL2
fidgetin-like 2
chr19_-_6375782 1.024 KHSRP
KH-type splicing regulatory protein
chr11_-_76059435 1.015 NM_001128922
LRRC32
leucine rich repeat containing 32
chr3_+_50281582 1.014 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr19_+_7874774 1.011 MAP2K7
mitogen-activated protein kinase kinase 7
chr20_-_2769245 1.010 NM_022760
FAM113A
family with sequence similarity 113, member A
chr19_+_447453 0.996 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr21_+_45649719 0.995


chr2_-_75641535 0.991 FAM176A
family with sequence similarity 176, member A
chr2_-_27457088 0.981 NM_144631
ZNF513
zinc finger protein 513
chr1_+_8306976 0.976 NM_001080397
SLC45A1
solute carrier family 45, member 1
chr20_-_2769120 0.975 FAM113A
family with sequence similarity 113, member A
chr17_-_36456949 0.970 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr17_+_1905104 0.965 NM_006497
HIC1
hypermethylated in cancer 1
chr19_-_18409971 0.965 NM_001170938
NM_016368
ISYNA1

inositol-3-phosphate synthase 1

chr16_-_71650034 0.960 NM_001164766
ZFHX3
zinc finger homeobox 3
chr12_-_113328271 0.957 NM_181486
TBX5
T-box 5
chr19_+_7874765 0.957 MAP2K7
mitogen-activated protein kinase kinase 7
chr12_+_50631734 0.956 ACVR1B
activin A receptor, type IB
chr2_+_27154938 0.954 NM_007046
EMILIN1
elastin microfibril interfacer 1
chr19_-_18409788 0.954 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr11_-_86343859 0.953 NM_012193
FZD4
frizzled homolog 4 (Drosophila)
chr19_-_4016467 0.936 ZBTB7A
zinc finger and BTB domain containing 7A
chr19_-_972122 0.936 NM_001033026
NM_033420
C19orf6

chromosome 19 open reading frame 6

chr20_+_21634515 0.930 PAX1
paired box 1
chr8_-_71146022 0.924 PRDM14
PR domain containing 14
chr19_-_1518875 0.919 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr11_-_66967481 0.910 CORO1B
coronin, actin binding protein, 1B
chr8_-_71146103 0.910 NM_024504
PRDM14
PR domain containing 14
chr19_-_971995 0.899 C19orf6
chromosome 19 open reading frame 6
chr11_-_45896144 0.896 NM_004813
NM_057174
PEX16

peroxisomal biogenesis factor 16

chr17_-_40923864 0.894 PLEKHM1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr20_-_43972949 0.892 PLTP
phospholipid transfer protein
chr16_-_1341766 0.878 NM_001001410
C16orf42
chromosome 16 open reading frame 42
chr19_+_7874762 0.876 MAP2K7
mitogen-activated protein kinase kinase 7
chr19_+_7874764 0.875 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr19_+_7874820 0.869 MAP2K7
mitogen-activated protein kinase kinase 7
chr21_+_46342440 0.864 NM_001849
NM_058174
NM_058175
COL6A2


collagen, type VI, alpha 2


chr20_-_33658823 0.863 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr14_+_23937766 0.862 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr7_+_100792841 0.856 NM_133457
EMID2
EMI domain containing 2
chr20_-_34925483 0.856 NM_080627
KIAA0889
KIAA0889
chr19_+_4255590 0.848 NM_024333
FSD1
fibronectin type III and SPRY domain containing 1
chr19_-_4674814 0.848 NM_139159
DPP9
dipeptidyl-peptidase 9
chr19_+_55045754 0.838 PTOV1
prostate tumor overexpressed 1
chr22_+_18085891 0.833 SEPT5
septin 5
chr20_+_21634293 0.832 NM_006192
PAX1
paired box 1
chr19_+_3045528 0.827 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr3_-_124650081 0.826 NM_183357
ADCY5
adenylate cyclase 5
chr19_-_52045890 0.822 NM_004069
NM_021575
AP2S1

adaptor-related protein complex 2, sigma 1 subunit

chr19_-_6375820 0.822 NM_003685
KHSRP
KH-type splicing regulatory protein
chr9_+_138900760 0.822 NM_021138
TRAF2
TNF receptor-associated factor 2
chr17_+_37222487 0.818 NM_021939
FKBP10
FK506 binding protein 10, 65 kDa
chr1_-_36562341 0.811 NM_018166
FAM176B
family with sequence similarity 176, member B
chr14_+_23654161 0.808 DCAF11
DDB1 and CUL4 associated factor 11
chr19_+_17047569 0.805 NM_001130065
NM_004145
MYO9B

myosin IXB

chr17_-_75808680 0.803 NM_000199
SGSH
N-sulfoglucosamine sulfohydrolase
chr21_-_32879617 0.801 NM_144659
TCP10L
t-complex 10 (mouse)-like
chr9_+_35480018 0.795 RUSC2
RUN and SH3 domain containing 2
chr3_-_49178762 0.795 CCDC71
coiled-coil domain containing 71
chr5_-_131591380 0.794 NM_001017974
NM_001142598
NM_001142599
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr8_-_93184629 0.793 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr17_+_37222726 0.792 FKBP10
FK506 binding protein 10, 65 kDa
chr17_+_7151653 0.791 EIF5A
eukaryotic translation initiation factor 5A
chr16_-_73857214 0.791 NM_001170720
NM_001170714
NM_001170718
BCAR1


breast cancer anti-estrogen resistance 1


chr3_-_49178773 0.788 NM_022903
CCDC71
coiled-coil domain containing 71
chr17_+_39620099 0.787 NM_177441
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr22_+_18085990 0.786 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chrX_-_30237403 0.783 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr19_+_38376980 0.779 LRP3
low density lipoprotein receptor-related protein 3
chr17_+_35472566 0.776 NM_001190918
NM_003250
NM_199334
THRA


thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)


chr7_+_78920846 0.774 LOC100505881
hypothetical LOC100505881
chr19_+_59064471 0.773 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr10_-_103444899 0.772 FBXW4
F-box and WD repeat domain containing 4
chr19_-_5291700 0.772 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr11_+_440408 0.771 PTDSS2
phosphatidylserine synthase 2
chr17_-_76985538 0.769


chr3_-_49178738 0.768 CCDC71
coiled-coil domain containing 71
chr20_-_33489383 0.766 NM_000557
GDF5
growth differentiation factor 5
chr19_-_4674791 0.766 DPP9
dipeptidyl-peptidase 9
chr17_+_39620108 0.764 TMUB2
transmembrane and ubiquitin-like domain containing 2
chr9_+_136673534 0.763 COL5A1
collagen, type V, alpha 1
chr9_+_35479989 0.763 NM_014806
RUSC2
RUN and SH3 domain containing 2
chr17_+_39619826 0.762 NM_001076674
NM_024107
TMUB2

transmembrane and ubiquitin-like domain containing 2

chr9_+_130222511 0.759 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr11_+_117907083 0.757 TMEM25
transmembrane protein 25
chr1_+_1233834 0.753 NM_153339
PUSL1
pseudouridylate synthase-like 1
chr17_+_35471971 0.752 NM_001190919
THRA
thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
chr19_-_63761559 0.748 UBE2M
ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
chrX_-_48929789 0.745 PRICKLE3
prickle homolog 3 (Drosophila)
chr6_-_33374678 0.743 RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr17_-_28644118 0.741 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr11_+_66381451 0.739 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr19_-_844184 0.738 MED16
mediator complex subunit 16
chr19_+_17691283 0.734 MAP1S
microtubule-associated protein 1S
chr9_+_115970599 0.733 COL27A1
collagen, type XXVII, alpha 1
chr16_+_66129481 0.732 FAM65A
family with sequence similarity 65, member A
chr19_-_6230927 0.726 NM_005934
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr19_+_2279679 0.710 SPPL2B
signal peptide peptidase-like 2B
chr20_+_2769338 0.709 NM_022575
NM_080413
VPS16

vacuolar protein sorting 16 homolog (S. cerevisiae)

chr19_-_14089560 0.708 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr1_+_9571518 0.707 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr4_+_134292630 0.705 PCDH10
protocadherin 10
chr19_+_7874701 0.702 MAP2K7
mitogen-activated protein kinase kinase 7
chr9_-_138454071 0.701 NM_019892
INPP5E
inositol polyphosphate-5-phosphatase, 72 kDa
chr16_+_56327127 0.700 NM_005886
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr16_+_658081 0.699 NM_138769
RHOT2
ras homolog gene family, member T2
chr20_-_61933012 0.699 ZBTB46
zinc finger and BTB domain containing 46
chr11_+_66381077 0.697 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr9_-_16860664 0.694 BNC2
basonuclin 2
chr19_+_3457264 0.693 NM_016263
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr9_-_130573671 0.689 ZER1
zer-1 homolog (C. elegans)
chr19_+_47480445 0.689 NM_015125
CIC
capicua homolog (Drosophila)
chr19_+_45664889 0.688 NM_020971
SPTBN4
spectrin, beta, non-erythrocytic 4
chr9_+_115678365 0.686 NM_133374
ZNF618
zinc finger protein 618
chr1_-_153213483 0.686 NM_001130041
NM_003029
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr22_+_18485095 0.682 RANBP1
RAN binding protein 1
chr16_-_11257539 0.680 NM_003745
SOCS1
suppressor of cytokine signaling 1
chr1_-_32460526 0.678 TMEM234
transmembrane protein 234
chr20_-_43972982 0.678 PLTP
phospholipid transfer protein
chr9_+_130942029 0.676 PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr17_-_7061641 0.676 NM_001128827
DLG4
discs, large homolog 4 (Drosophila)
chr17_-_23716391 0.676 NM_001080837
SEBOX
SEBOX homeobox
chr14_+_76298693 0.672 VASH1
vasohibin 1
chr5_-_149809424 0.671 RPS14
ribosomal protein S14
chr17_-_74432671 0.670 TIMP2
TIMP metallopeptidase inhibitor 2
chr16_+_56327168 0.670 KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr11_+_47227009 0.668 NM_001130102
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr19_+_59064795 0.668 MYADM
myeloid-associated differentiation marker
chr9_-_139128777 0.666 DPP7
dipeptidyl-peptidase 7
chr17_-_37221976 0.662 NM_006455
LEPREL4
leprecan-like 4
chr14_+_22375632 0.662 NM_004995
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr16_+_68705714 0.661 PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr9_-_109291575 0.660 KLF4
Kruppel-like factor 4 (gut)
chr14_-_60260211 0.659 NM_017420
SIX4
SIX homeobox 4
chr19_+_54723044 0.655 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr7_-_75461897 0.653 NM_031925
TMEM120A
transmembrane protein 120A
chr3_-_48647811 0.653 SLC26A6
solute carrier family 26, member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 2.26e-06 GO:0009653 anatomical structure morphogenesis
1.55 3.88e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.26 3.51e-05 GO:0048856 anatomical structure development
1.28 4.03e-05 GO:0048731 system development
1.76 4.07e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.40 5.11e-05 GO:0007399 nervous system development
1.13 5.15e-05 GO:0065007 biological regulation
1.31 5.88e-05 GO:0048519 negative regulation of biological process
1.15 6.45e-05 GO:0050794 regulation of cellular process
1.64 1.50e-04 GO:0010629 negative regulation of gene expression
1.27 1.67e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 1.76e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.40 1.79e-04 GO:0009966 regulation of signal transduction
1.28 1.99e-04 GO:0010468 regulation of gene expression
1.13 2.01e-04 GO:0050789 regulation of biological process
1.67 2.06e-04 GO:0051253 negative regulation of RNA metabolic process
1.36 2.23e-04 GO:0023051 regulation of signaling
1.67 2.54e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.26 2.70e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.61 2.74e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.28 3.33e-04 GO:0048522 positive regulation of cellular process
1.26 3.78e-04 GO:0048518 positive regulation of biological process
1.58 4.52e-04 GO:0010628 positive regulation of gene expression
1.30 4.73e-04 GO:0048523 negative regulation of cellular process
1.28 5.41e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.29 5.63e-04 GO:0051252 regulation of RNA metabolic process
1.53 8.59e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.58 9.98e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.59 1.02e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 1.06e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.25 1.15e-03 GO:0009889 regulation of biosynthetic process
1.25 1.22e-03 GO:0031326 regulation of cellular biosynthetic process
1.30 1.27e-03 GO:0030154 cell differentiation
1.21 1.38e-03 GO:0080090 regulation of primary metabolic process
1.29 1.54e-03 GO:0048869 cellular developmental process
1.20 1.54e-03 GO:0032502 developmental process
1.47 1.58e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.28 1.61e-03 GO:0006355 regulation of transcription, DNA-dependent
1.26 1.63e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.31 1.67e-03 GO:0048583 regulation of response to stimulus
1.54 1.93e-03 GO:0009890 negative regulation of biosynthetic process
1.08 1.99e-03 GO:0009987 cellular process
1.57 1.99e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.22 2.08e-03 GO:0060255 regulation of macromolecule metabolic process
1.21 2.26e-03 GO:0007275 multicellular organismal development
1.21 2.53e-03 GO:0031323 regulation of cellular metabolic process
1.64 4.04e-03 GO:0072358 cardiovascular system development
1.64 4.04e-03 GO:0072359 circulatory system development
2.53 4.31e-03 GO:0030326 embryonic limb morphogenesis
2.53 4.31e-03 GO:0035113 embryonic appendage morphogenesis
1.53 4.34e-03 GO:0051254 positive regulation of RNA metabolic process
1.46 4.62e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.46 4.67e-03 GO:0009891 positive regulation of biosynthetic process
2.36 6.55e-03 GO:0048736 appendage development
2.36 6.55e-03 GO:0060173 limb development
1.19 6.73e-03 GO:0019222 regulation of metabolic process
1.94 6.88e-03 GO:0048514 blood vessel morphogenesis
1.84 7.47e-03 GO:0001568 blood vessel development
2.38 7.98e-03 GO:0035107 appendage morphogenesis
2.38 7.98e-03 GO:0035108 limb morphogenesis
1.46 1.26e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.36 1.76e-02 GO:0031325 positive regulation of cellular metabolic process
1.40 1.84e-02 GO:0009892 negative regulation of metabolic process
1.36 2.04e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.41 2.79e-02 GO:0022008 neurogenesis
1.71 2.82e-02 GO:0060284 regulation of cell development
1.45 2.90e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41 4.01e-02 GO:0048699 generation of neurons
1.74 4.13e-02 GO:0001944 vasculature development
1.33 4.43e-02 GO:0009893 positive regulation of metabolic process
1.46 4.65e-02 GO:0009790 embryo development
1.33 4.87e-02 GO:0051239 regulation of multicellular organismal process
1.40 4.98e-02 GO:0031324 negative regulation of cellular metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 1.50e-04 GO:0005622 intracellular
1.08 2.50e-04 GO:0044424 intracellular part
1.71 3.24e-03 GO:0005773 vacuole
1.75 6.28e-03 GO:0000323 lytic vacuole
1.75 6.28e-03 GO:0005764 lysosome
1.08 7.02e-03 GO:0043226 organelle
1.08 8.53e-03 GO:0043229 intracellular organelle
1.09 1.07e-02 GO:0005737 cytoplasm
1.57 1.51e-02 GO:0043005 neuron projection
1.03 1.85e-02 GO:0044464 cell part
1.03 1.92e-02 GO:0005623 cell
2.44 2.35e-02 GO:0005604 basement membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.50e-08 GO:0005515 protein binding
1.66 5.20e-07 GO:0043565 sequence-specific DNA binding
1.52 1.27e-06 GO:0030528 transcription regulator activity
1.52 2.37e-06 GO:0001071 nucleic acid binding transcription factor activity
1.52 2.37e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.08 1.16e-05 GO:0005488 binding
1.28 7.59e-05 GO:0003677 DNA binding
2.00 5.33e-04 GO:0000975 regulatory region DNA binding
2.00 5.33e-04 GO:0001067 regulatory region nucleic acid binding
2.00 5.33e-04 GO:0044212 transcription regulatory region DNA binding
1.75 1.47e-03 GO:0016563 transcription activator activity
1.96 2.00e-03 GO:0010843 promoter binding
1.54 2.92e-02 GO:0019904 protein domain specific binding
1.62 4.10e-02 GO:0003779 actin binding