Motif ID: E2F1..5.p2

Z-value: 2.484


Transcription factors associated with E2F1..5.p2:

Gene SymbolEntrez IDGene Name
E2F1 1869 E2F transcription factor 1
E2F2 1870 E2F transcription factor 2
E2F3 1871 E2F transcription factor 3
E2F4 1874 E2F transcription factor 4, p107/p130-binding
E2F5 1875 E2F transcription factor 5, p130-binding



Activity profile for motif E2F1..5.p2.

activity profile for motif E2F1..5.p2


Sorted Z-values histogram for motif E2F1..5.p2

Sorted Z-values for motif E2F1..5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of E2F1..5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_17124974 3.746 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr6_+_72949092 2.173 RIMS1
regulating synaptic membrane exocytosis 1
chr6_-_52257500 1.845 NM_002388
MCM3
minichromosome maintenance complex component 3
chr6_-_52257475 1.834 MCM3
minichromosome maintenance complex component 3
chr5_-_146869613 1.737 DPYSL3
dihydropyrimidinase-like 3
chr6_-_52257431 1.698 MCM3
minichromosome maintenance complex component 3
chr15_+_45263517 1.616 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr10_+_96295511 1.606 NM_018063
HELLS
helicase, lymphoid-specific
chr7_-_27153892 1.573 NM_024014
HOXA6
homeobox A6
chr6_+_27941012 1.509 NM_003511
HIST1H2AI
HIST1H2AL
histone cluster 1, H2ai
histone cluster 1, H2al
chr5_-_146869811 1.464 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr14_+_85069217 1.464


chr6_+_27208763 1.370 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr8_+_31616809 1.344 NM_013962
NRG1
neuregulin 1
chr10_-_131652007 1.313 NM_001005463
EBF3
early B-cell factor 3
chr20_-_5048443 1.280 NM_182649
PCNA
proliferating cell nuclear antigen
chr6_-_132314004 1.263 NM_001901
CTGF
connective tissue growth factor
chr8_-_24869945 1.240 NM_006158
NEFL
neurofilament, light polypeptide
chrX_-_131451675 1.232 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chr7_+_113513726 1.232 FOXP2
forkhead box P2
chr6_-_27208507 1.223 NM_021058
HIST1H2BJ
histone cluster 1, H2bj
chr15_+_42507123 1.223 CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr16_+_71256497 1.216


chr13_-_25523164 1.141 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr7_+_113513828 1.132 FOXP2
forkhead box P2
chr12_-_75983329 1.116 NM_203394
E2F7
E2F transcription factor 7
chr1_-_226712140 1.114 NM_033445
HIST3H2A
histone cluster 3, H2a
chr2_+_10180304 1.091 NM_001034
RRM2
ribonucleotide reductase M2
chr19_+_54786723 1.073 NM_020719
PRR12
proline rich 12
chr15_+_42507057 1.071 CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr3_-_134863316 1.058 NM_007027
TOPBP1
topoisomerase (DNA) II binding protein 1
chr6_+_26153590 1.052 NM_003531
HIST1H3C
histone cluster 1, H3c
chr18_-_68361742 1.044 CBLN2
cerebellin 2 precursor
chr4_-_104860277 1.041 NM_001059
TACR3
tachykinin receptor 3
chr4_+_72271218 1.039 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr4_+_134289893 1.026 NM_020815
NM_032961
PCDH10

protocadherin 10

chr18_-_5620629 1.020 EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr22_+_34126154 1.011 MCM5
minichromosome maintenance complex component 5
chr6_+_88356503 0.995 NM_001197259
NM_012381
NM_181837
ORC3


origin recognition complex, subunit 3


chrX_+_101792949 0.987 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr2_-_139254273 0.979 NM_007226
NXPH2
neurexophilin 2
chr9_-_25668230 0.978 TUSC1
tumor suppressor candidate 1
chr3_-_143350898 0.978 NM_001178138
NM_001178139
TFDP2

transcription factor Dp-2 (E2F dimerization partner 2)

chr10_-_131652364 0.976 EBF3
early B-cell factor 3
chr22_+_34126104 0.976 NM_006739
MCM5
minichromosome maintenance complex component 5
chr6_+_135544214 0.963 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr22_-_40194602 0.959 NM_032758
PHF5A
PHD finger protein 5A
chr17_+_4784524 0.955 RNF167
ring finger protein 167
chr9_+_35782405 0.955 NM_003995
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr22_+_49293520 0.952 NCAPH2
non-SMC condensin II complex, subunit H2
chr14_+_37748345 0.950 SSTR1
somatostatin receptor 1
chr14_+_73621408 0.932 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr8_+_69405510 0.932 NM_001195639
NM_052958
C8orf34

chromosome 8 open reading frame 34

chr20_+_5879297 0.924 NM_032485
NM_182802
MCM8

minichromosome maintenance complex component 8

chr2_+_219141761 0.915 NM_005444
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr1_+_226712430 0.908 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr2_-_47022406 0.898 NM_001171508
NM_001171511
MCFD2

multiple coagulation factor deficiency 2

chr8_-_95634845 0.890 NM_015496
NM_183009
KIAA1429

KIAA1429

chr6_+_135544138 0.890 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr5_+_63838183 0.887 NM_001029875
RGS7BP
regulator of G-protein signaling 7 binding protein
chr5_+_72897323 0.886 NM_032175
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr7_+_113513600 0.885 FOXP2
forkhead box P2
chr9_-_35069520 0.867 FANCG
Fanconi anemia, complementation group G
chr5_+_122452739 0.840 NM_001136239
PRDM6
PR domain containing 6
chr6_+_27883877 0.839 NM_003509
HIST1H2AI
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H3f
chr4_-_147079410 0.825


chr6_+_20510019 0.820 NM_001949
E2F3
E2F transcription factor 3
chr7_-_27149750 0.812 NM_019102
HOXA5
homeobox A5
chr10_+_22580992 0.801


chr11_+_12987455 0.798 NM_001080521
RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr8_-_75396016 0.792 NM_020647
JPH1
junctophilin 1
chr6_-_26358811 0.782 NM_021018
HIST1H3F
histone cluster 1, H3f
chr8_-_121526568 0.779 MRPL13
mitochondrial ribosomal protein L13
chr13_+_114098045 0.758 NM_001164144
NM_001164145
NM_032436
ZNF828


zinc finger protein 828


chr4_+_134292630 0.754 PCDH10
protocadherin 10
chr14_-_54727958 0.750 NM_001146015
NM_014750
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr6_-_27883662 0.738 NM_003519
HIST1H2BL
histone cluster 1, H2bl
chr19_+_15079141 0.734 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr6_-_116681863 0.733 NM_021648
TSPYL4
TSPY-like 4
chr5_+_139473873 0.727 NM_005859
PURA
purine-rich element binding protein A
chr3_-_137953876 0.726 NM_005862
STAG1
stromal antigen 1
chrX_-_99873152 0.726 NM_001174068
NM_080737
SYTL4

synaptotagmin-like 4

chr1_+_35811557 0.708 NM_178548
TFAP2E
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr22_+_34126294 0.706 MCM5
minichromosome maintenance complex component 5
chr13_+_72199981 0.706 NM_024808
C13orf34
chromosome 13 open reading frame 34
chr4_-_170915602 0.704 NM_017867
C4orf27
chromosome 4 open reading frame 27
chr12_+_5411534 0.699 NM_001102654
NTF3
neurotrophin 3
chr17_-_9419864 0.693 NM_004853
STX8
syntaxin 8
chr6_-_88356445 0.692 NM_020320
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr8_-_121526514 0.690 MRPL13
mitochondrial ribosomal protein L13
chr4_+_30331543 0.689 PCDH7
protocadherin 7
chr1_-_210275402 0.688 NM_015434
INTS7
integrator complex subunit 7
chr5_+_126654354 0.688 NM_032446
MEGF10
multiple EGF-like-domains 10
chr2_-_219141199 0.686 NM_020935
USP37
ubiquitin specific peptidase 37
chr4_+_55218663 0.684 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr7_+_119700924 0.682 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr1_-_148050534 0.681 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr6_+_135544170 0.680 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr1_-_91259601 0.677 NM_016620
ZNF644
zinc finger protein 644
chr14_+_34521945 0.677 SRP54
signal recognition particle 54kDa
chr14_+_64949447 0.675 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chrX_-_103386215 0.668 NM_153448
ESX1
ESX homeobox 1
chr15_-_81743198 0.661 BNC1
basonuclin 1
chr3_-_123036597 0.659 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr9_-_4289574 0.659 GLIS3
GLIS family zinc finger 3
chr12_-_47396724 0.651 NM_001240
CCNT1
cyclin T1
chr1_-_200946038 0.644 NM_177402
SYT2
synaptotagmin II
chr2_+_15998090 0.640 NM_005378
MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr21_-_27139143 0.637 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr12_-_107479294 0.634 NM_014706
SART3
squamous cell carcinoma antigen recognized by T cells 3
chr2_+_10180145 0.633 NM_001165931
RRM2
ribonucleotide reductase M2
chr2_-_160627366 0.631 NM_001007267
NM_001195641
NM_007366
PLA2R1


phospholipase A2 receptor 1, 180kDa


chr10_-_105604942 0.631 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr6_-_88356411 0.630 RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr6_-_27222556 0.629 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr6_+_90596348 0.629 CASP8AP2
caspase 8 associated protein 2
chr2_+_15998010 0.628 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr22_+_49293493 0.626 NM_001185011
NM_014551
NM_152299
NCAPH2


non-SMC condensin II complex, subunit H2


chr3_+_64645819 0.624 LOC100507098
hypothetical LOC100507098
chr7_+_120378052 0.624 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr9_-_35069751 0.619 NM_004629
FANCG
Fanconi anemia, complementation group G
chr2_-_10747553 0.617 NM_024894
NOL10
nucleolar protein 10
chr3_+_135996990 0.615 EPHB1
EPH receptor B1
chr6_+_43036442 0.614 NM_018960
GNMT
glycine N-methyltransferase
chr18_+_52469559 0.613 NM_015285
NM_052834
WDR7

WD repeat domain 7

chr18_-_53621277 0.613 NM_005603
ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr3_-_10003512 0.611 NM_018447
TMEM111
transmembrane protein 111
chr14_+_35365266 0.611 NM_032352
BRMS1L
breast cancer metastasis-suppressor 1-like
chr3_-_51950919 0.610 NM_004704
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr17_-_9419849 0.607 STX8
syntaxin 8
chr5_-_139760838 0.607


chr9_-_112840064 0.605 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr5_+_1854493 0.605 NM_004553
NDUFS6
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr18_+_11841388 0.603 NM_020412
CHMP1B
chromatin modifying protein 1B
chr9_-_21984414 0.598 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr2_-_164300758 0.597 NM_018086
FIGN
fidgetin
chr11_-_62379788 0.595 SNHG1
small nucleolar RNA host gene 1 (non-protein coding)
chr8_-_120937215 0.592 NM_024094
DSCC1
defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr16_+_66153810 0.592 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr3_-_10003344 0.591 TMEM111
transmembrane protein 111
chr1_-_100370994 0.588 NM_194292
SASS6
spindle assembly 6 homolog (C. elegans)
chr8_-_121526806 0.587 NM_014078
MRPL13
mitochondrial ribosomal protein L13
chr13_+_33290254 0.583 RFC3
replication factor C (activator 1) 3, 38kDa
chr2_+_219141546 0.581 RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr4_-_130233855 0.579 NM_144643
SCLT1
sodium channel and clathrin linker 1
chr11_-_19219000 0.571 NM_024680
E2F8
E2F transcription factor 8
chr5_+_50714714 0.569 NM_002202
ISL1
ISL LIM homeobox 1
chr2_+_131966970 0.567 LOC150776
sphingomyelin phosphodiesterase 4, neutral membrane pseudogene
chr1_-_26058434 0.567 NM_024037
C1orf135
chromosome 1 open reading frame 135
chr22_+_22639025 0.566 NM_001084393
DDTL
D-dopachrome tautomerase-like
chr5_+_94981735 0.565 NM_199243
GPR150
G protein-coupled receptor 150
chr6_-_27914095 0.563 NM_003510
HIST1H2AK
histone cluster 1, H2ak
chr1_-_68470585 0.559 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr14_-_64040072 0.554 NM_006977
ZBTB25
zinc finger and BTB domain containing 25
chr1_-_147665783 0.553 HIST2H2BF
histone cluster 2, H2bf
chr14_+_92743381 0.553 UBR7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr12_-_47532171 0.551 NM_004818
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr4_+_30330963 0.545 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr11_+_62380042 0.544 NM_001012662
NM_001012664
NM_002394
NM_001012661
NM_001012663
SLC3A2




solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2




chr3_-_62334229 0.543 NM_018008
FEZF2
FEZ family zinc finger 2
chr6_+_90596290 0.541 NM_001137667
NM_001137668
NM_012115
CASP8AP2


caspase 8 associated protein 2


chr19_-_57082907 0.541 NM_001135590
NM_032679
ZNF577

zinc finger protein 577

chr2_-_10747438 0.540 NOL10
nucleolar protein 10
chr13_+_102047286 0.540 NM_003291
TPP2
tripeptidyl peptidase II
chr8_+_121526823 0.536 NM_022045
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr7_+_121300446 0.529 PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chrX_-_62891066 0.523 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr20_-_5879036 0.522 NM_015939
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr19_-_10305186 0.522 NM_133452
RAVER1
ribonucleoprotein, PTB-binding 1
chr1_-_119333701 0.521 NM_152380
TBX15
T-box 15
chr12_-_55013987 0.521 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr11_+_118374071 0.518 CCDC84
coiled-coil domain containing 84
chr9_-_23811808 0.516 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_-_74154272 0.515 NM_173827
COX18
COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr2_-_667367 0.513 NM_152834
TMEM18
transmembrane protein 18
chr5_+_96024434 0.513 CAST
calpastatin
chr2_-_47022374 0.511 MCFD2
multiple coagulation factor deficiency 2
chrX_+_130984912 0.510 NM_001042453
NM_016542
MST4

serine/threonine protein kinase MST4

chr6_-_27968906 0.506 NM_003514
HIST1H2AM
histone cluster 1, H2am
chr10_+_112317401 0.506 NM_005445
SMC3
structural maintenance of chromosomes 3
chr8_-_132122016 0.505 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr8_+_69026895 0.502 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr9_-_23811842 0.499 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr9_+_85785456 0.499 NM_024945
RMI1
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chr3_-_49868889 0.498 NM_005879
TRAIP
TRAF interacting protein
chr9_-_21984379 0.497 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr9_-_78710698 0.495 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr3_+_148609841 0.490 NM_003412
ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr6_+_26333361 0.488 NM_003532
HIST1H3E
histone cluster 1, H3e
chr10_+_75580914 0.487 NM_006721
ADK
adenosine kinase
chr8_+_69027166 0.486 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chrX_+_101887562 0.485 NM_001142529
NM_001142530
BHLHB9

basic helix-loop-helix domain containing, class B, 9

chr10_-_123724251 0.483 NSMCE4A
non-SMC element 4 homolog A (S. cerevisiae)
chr13_+_44592647 0.481 GTF2F2
general transcription factor IIF, polypeptide 2, 30kDa
chr1_-_29321599 0.479 NM_001171868
TMEM200B
transmembrane protein 200B
chr3_+_10003579 0.478 LOC442075
hypothetical LOC442075
chr2_+_188865796 0.478 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr13_+_97426713 0.476 IPO5
importin 5
chr17_-_34860840 0.475 NM_004774
MED1
mediator complex subunit 1
chr5_-_37406643 0.474 NM_004298
NUP155
nucleoporin 155kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.17 2.84e-20 GO:0007049 cell cycle
1.60 1.47e-17 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.66 2.65e-16 GO:0090304 nucleic acid metabolic process
2.27 6.08e-15 GO:0022403 cell cycle phase
1.46 2.27e-14 GO:0071840 cellular component organization or biogenesis
1.47 2.44e-14 GO:0016043 cellular component organization
1.54 2.80e-14 GO:0071841 cellular component organization or biogenesis at cellular level
2.12 4.27e-14 GO:0022402 cell cycle process
2.33 7.62e-14 GO:0006259 DNA metabolic process
1.54 1.83e-13 GO:0071842 cellular component organization at cellular level
2.27 3.27e-13 GO:0051276 chromosome organization
3.77 3.31e-13 GO:0071103 DNA conformation change
3.93 2.33e-12 GO:0006323 DNA packaging
4.14 3.06e-12 GO:0071824 protein-DNA complex subunit organization
4.42 3.27e-12 GO:0031497 chromatin assembly
1.36 7.37e-12 GO:0044260 cellular macromolecule metabolic process
1.45 1.00e-11 GO:0034641 cellular nitrogen compound metabolic process
4.16 1.40e-11 GO:0065004 protein-DNA complex assembly
1.14 5.85e-11 GO:0009987 cellular process
2.19 9.46e-11 GO:0000278 mitotic cell cycle
4.09 1.29e-10 GO:0034728 nucleosome organization
3.24 1.29e-10 GO:0006260 DNA replication
1.65 1.40e-10 GO:0006996 organelle organization
1.41 3.21e-10 GO:0006807 nitrogen compound metabolic process
4.15 8.96e-10 GO:0006334 nucleosome assembly
3.50 9.03e-10 GO:0006333 chromatin assembly or disassembly
1.74 2.10e-09 GO:0044085 cellular component biogenesis
1.77 9.43e-09 GO:0022607 cellular component assembly
1.93 1.27e-08 GO:0071844 cellular component assembly at cellular level
2.14 1.54e-08 GO:0006974 response to DNA damage stimulus
1.28 1.59e-08 GO:0043170 macromolecule metabolic process
2.48 4.34e-08 GO:0051325 interphase
2.22 4.72e-08 GO:0000279 M phase
2.30 1.49e-07 GO:0034622 cellular macromolecular complex assembly
2.40 5.39e-07 GO:0051329 interphase of mitotic cell cycle
1.52 8.76e-07 GO:0034645 cellular macromolecule biosynthetic process
2.29 9.52e-07 GO:0006281 DNA repair
1.85 1.36e-06 GO:0065003 macromolecular complex assembly
1.51 2.40e-06 GO:0009059 macromolecule biosynthetic process
2.02 2.98e-06 GO:0034621 cellular macromolecular complex subunit organization
1.20 4.72e-06 GO:0044237 cellular metabolic process
1.72 1.16e-05 GO:0043933 macromolecular complex subunit organization
1.85 1.18e-05 GO:0051726 regulation of cell cycle
1.20 1.20e-05 GO:0044238 primary metabolic process
1.97 2.59e-05 GO:0006325 chromatin organization
2.14 2.62e-05 GO:0051301 cell division
2.14 3.67e-05 GO:0010564 regulation of cell cycle process
2.86 5.35e-05 GO:0006310 DNA recombination
2.21 8.20e-05 GO:0000280 nuclear division
2.21 8.20e-05 GO:0007067 mitosis
1.36 9.55e-05 GO:0044249 cellular biosynthetic process
3.68 1.02e-04 GO:0006261 DNA-dependent DNA replication
1.44 1.16e-04 GO:0016070 RNA metabolic process
1.27 2.02e-04 GO:0031323 regulation of cellular metabolic process
2.15 2.17e-04 GO:0000087 M phase of mitotic cell cycle
2.14 2.45e-04 GO:0048285 organelle fission
1.33 3.38e-04 GO:0031326 regulation of cellular biosynthetic process
1.82 3.99e-04 GO:0016071 mRNA metabolic process
1.32 6.24e-04 GO:0009889 regulation of biosynthetic process
1.27 7.77e-04 GO:0060255 regulation of macromolecule metabolic process
1.62 9.52e-04 GO:0033554 cellular response to stress
2.93 1.05e-03 GO:0007059 chromosome segregation
1.26 1.14e-03 GO:0080090 regulation of primary metabolic process
1.33 1.19e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.32 1.25e-03 GO:0009058 biosynthetic process
2.61 1.30e-03 GO:0000082 G1/S transition of mitotic cell cycle
1.39 1.34e-03 GO:0010467 gene expression
1.15 2.26e-03 GO:0050794 regulation of cellular process
1.23 2.62e-03 GO:0019222 regulation of metabolic process
1.31 2.62e-03 GO:0010468 regulation of gene expression
2.48 2.86e-03 GO:0000226 microtubule cytoskeleton organization
1.31 3.18e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.29 3.18e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.30 3.28e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 3.57e-03 GO:0008152 metabolic process
5.57 7.65e-03 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus
5.57 7.65e-03 GO:0016444 somatic cell DNA recombination
2.66 1.14e-02 GO:0051320 S phase
5.85 1.47e-02 GO:0007062 sister chromatid cohesion
1.30 2.21e-02 GO:0051252 regulation of RNA metabolic process
2.60 2.66e-02 GO:0000084 S phase of mitotic cell cycle
2.55 3.70e-02 GO:0051321 meiotic cell cycle
1.12 4.11e-02 GO:0050789 regulation of biological process
6.83 4.67e-02 GO:0071897 DNA biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.51 3.68e-38 GO:0005634 nucleus
1.28 2.05e-35 GO:0043226 organelle
1.28 3.54e-35 GO:0043229 intracellular organelle
1.30 5.32e-31 GO:0043227 membrane-bounded organelle
1.30 6.33e-31 GO:0043231 intracellular membrane-bounded organelle
1.20 1.36e-27 GO:0044424 intracellular part
1.18 4.67e-26 GO:0005622 intracellular
1.79 2.46e-24 GO:0044428 nuclear part
1.39 2.59e-22 GO:0044446 intracellular organelle part
2.66 1.20e-21 GO:0005694 chromosome
1.82 2.41e-21 GO:0031981 nuclear lumen
1.38 4.53e-21 GO:0044422 organelle part
1.71 6.40e-21 GO:0070013 intracellular organelle lumen
1.68 6.74e-20 GO:0031974 membrane-enclosed lumen
1.68 8.14e-20 GO:0043233 organelle lumen
1.91 5.40e-18 GO:0005654 nucleoplasm
2.59 1.77e-16 GO:0044427 chromosomal part
1.41 9.37e-13 GO:0032991 macromolecular complex
1.48 2.18e-12 GO:0043228 non-membrane-bounded organelle
1.48 2.18e-12 GO:0043232 intracellular non-membrane-bounded organelle
3.98 5.82e-10 GO:0032993 protein-DNA complex
2.76 8.14e-10 GO:0000785 chromatin
2.68 6.96e-08 GO:0000228 nuclear chromosome
1.05 1.13e-07 GO:0044464 cell part
1.05 1.18e-07 GO:0005623 cell
4.34 2.06e-07 GO:0000786 nucleosome
1.78 1.12e-06 GO:0044451 nucleoplasm part
2.69 3.25e-06 GO:0044454 nuclear chromosome part
1.30 4.80e-05 GO:0043234 protein complex
1.74 6.56e-04 GO:0030529 ribonucleoprotein complex
2.51 8.04e-04 GO:0000793 condensed chromosome
8.78 4.10e-03 GO:0042555 MCM complex
2.29 1.06e-02 GO:0000775 chromosome, centromeric region
3.80 1.52e-02 GO:0005657 replication fork

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.53 4.75e-19 GO:0003676 nucleic acid binding
1.61 4.13e-16 GO:0003677 DNA binding
1.12 2.46e-12 GO:0005488 binding
1.22 5.36e-11 GO:0005515 protein binding
11.70 2.52e-04 GO:0032135 DNA insertion or deletion binding
1.54 3.09e-04 GO:0030528 transcription regulator activity
3.70 3.99e-04 GO:0003697 single-stranded DNA binding
2.34 4.75e-04 GO:0043566 structure-specific DNA binding
2.60 5.30e-04 GO:0003690 double-stranded DNA binding
1.53 5.62e-04 GO:0001071 nucleic acid binding transcription factor activity
1.53 5.62e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.32 7.89e-04 GO:0000166 nucleotide binding
6.69 3.39e-03 GO:0030983 mismatched DNA binding
3.41 1.96e-02 GO:0003684 damaged DNA binding
1.54 2.24e-02 GO:0043565 sequence-specific DNA binding
11.70 3.53e-02 GO:0032138 single base insertion or deletion binding