Motif ID: MZF1.p2

Z-value: 2.055


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1



Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_113574925 5.676 NM_001143945
GAS6
growth arrest-specific 6
chr7_+_5289079 2.777 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr3_+_42675841 2.324 ZBTB47
zinc finger and BTB domain containing 47
chr15_-_86600658 2.319 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr2_-_216944911 2.149 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr6_+_21774624 2.102 FLJ22536
hypothetical locus LOC401237
chr2_+_45022540 2.042 NM_005413
SIX3
SIX homeobox 3
chr21_-_27261276 1.985 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr8_+_22513043 1.887 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr19_-_55914837 1.846


chr19_-_56178882 1.807 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr5_+_152850276 1.771 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr13_+_87122778 1.769 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr12_-_6313219 1.757 TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr2_-_152663748 1.755 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr11_-_60475558 1.618 NM_016582
SLC15A3
solute carrier family 15, member 3
chr10_-_105604942 1.606 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr14_-_36059084 1.576 NM_001079668
NKX2-1
NK2 homeobox 1
chr1_+_15957832 1.554 NM_017556
FBLIM1
filamin binding LIM protein 1
chr1_+_2975590 1.483 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr7_-_78920806 1.480 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_-_27120015 1.477 HOXA3
homeobox A3
chr7_+_55054152 1.455 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr17_+_7728819 1.453 NM_001005271
CHD3
chromodomain helicase DNA binding protein 3
chr13_-_43259032 1.437 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr2_-_152663454 1.427 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr7_+_78920846 1.411 LOC100505881
hypothetical LOC100505881
chr7_-_23476497 1.407 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chrX_+_100361588 1.404 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr7_-_27136876 1.386 NM_002141
HOXA4
homeobox A4
chr12_+_52689062 1.385 NM_022658
HOXC8
homeobox C8
chr4_-_187764213 1.370


chr5_+_79021401 1.357 NM_153610
CMYA5
cardiomyopathy associated 5
chr9_+_8848130 1.334


chr11_+_66499323 1.323 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr20_-_61574259 1.307 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr22_-_28972683 1.298 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr10_+_71231693 1.297 COL13A1
collagen, type XIII, alpha 1
chr19_-_53187151 1.296 NM_001128326
BSPH1
binder of sperm protein homolog 1
chr11_-_27700180 1.288 NM_170731
BDNF
brain-derived neurotrophic factor
chr20_-_21442663 1.275 NM_002509
NKX2-2
NK2 homeobox 2
chr11_+_36354110 1.260 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr17_-_69151821 1.253 NM_001144952
SDK2
sidekick homolog 2 (chicken)
chr3_-_48516486 1.251 NM_016479
SHISA5
shisa homolog 5 (Xenopus laevis)
chr12_-_6354818 1.240 SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr17_-_959007 1.236 NM_001092
ABR
active BCR-related gene
chr3_+_148610516 1.234 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr4_-_46086528 1.225 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr9_-_34579679 1.225 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr17_+_18255753 1.209 FLJ35934
FLJ35934
chr14_-_22904074 1.193


chr17_-_39632845 1.184 ATXN7L3
ataxin 7-like 3
chr14_-_36058648 1.182 NM_003317
NKX2-1
NK2 homeobox 1
chr9_+_139241838 1.171 NM_001190228
LOC643596
hypothetical LOC643596
chr9_+_33807213 1.162 UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr2_+_137239583 1.162 THSD7B
thrombospondin, type I, domain containing 7B
chr7_-_127458231 1.145 NM_022143
LRRC4
leucine rich repeat containing 4
chr4_-_73653331 1.141 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr5_+_129268352 1.139 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr9_-_116608113 1.135 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr5_-_127901633 1.126 NM_001999
FBN2
fibrillin 2
chr14_-_47213906 1.104 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr19_-_59676153 1.098 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr22_-_44751671 1.097 NM_058238
WNT7B
wingless-type MMTV integration site family, member 7B
chr20_-_22512893 1.094 FOXA2
forkhead box A2
chr4_+_37569093 1.091 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr9_-_121171400 1.076 NM_014618
DBC1
deleted in bladder cancer 1
chr18_+_54682261 1.075 ZNF532
zinc finger protein 532
chr15_-_59308770 1.064 NM_134261
RORA
RAR-related orphan receptor A
chr2_+_176680251 1.064 NM_021192
HOXD11
homeobox D11
chr5_+_131437383 1.063 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr14_-_22904257 1.062 EFS
embryonal Fyn-associated substrate
chr9_+_115957537 1.047 COL27A1
collagen, type XXVII, alpha 1
chr9_-_4290028 1.045 NM_001042413
GLIS3
GLIS family zinc finger 3
chr19_-_54258935 1.037 NM_006179
NTF4
neurotrophin 4
chr14_-_22904218 1.029 EFS
embryonal Fyn-associated substrate
chr17_+_24742068 1.026 NM_020791
TAOK1
TAO kinase 1
chr10_+_119292699 1.026


chr15_-_77170135 1.024 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr1_+_201711578 1.018 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr1_-_154484341 1.012 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr15_-_59308708 1.010 RORA
RAR-related orphan receptor A
chr19_-_60412624 1.001 NM_001161440
NM_002842
PTPRH

protein tyrosine phosphatase, receptor type, H

chr14_+_104244998 0.999 INF2
inverted formin, FH2 and WH2 domain containing
chr3_+_189354167 0.995 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr4_+_54660954 0.990 NM_133267
GSX2
GS homeobox 2
chr16_+_29819647 0.979 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr10_+_71231649 0.978 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr11_-_27697768 0.973 NM_001143807
BDNF
brain-derived neurotrophic factor
chr1_-_34404029 0.971 NM_052896
CSMD2
CUB and Sushi multiple domains 2
chrX_+_66680593 0.970 NM_000044
AR
androgen receptor
chr10_-_121292139 0.960 NM_001005339
RGS10
regulator of G-protein signaling 10
chr20_-_3713509 0.959 CENPB
centromere protein B, 80kDa
chr2_+_26768894 0.955 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr12_-_47468985 0.950 NM_020983
ADCY6
adenylate cyclase 6
chr17_-_72045218 0.946 NM_134268
CYGB
cytoglobin
chr19_-_242335 0.936 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr5_-_141981083 0.934 NM_001144892
FGF1
fibroblast growth factor 1 (acidic)
chr11_+_61352348 0.932 FADS2
fatty acid desaturase 2
chr3_-_159306532 0.929 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr17_+_39741306 0.923 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr15_+_66658626 0.920 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr6_-_150253729 0.919 NM_139165
RAET1E
retinoic acid early transcript 1E
chr22_-_49063088 0.919 PLXNB2
plexin B2
chr11_-_68537243 0.916 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr20_-_47618059 0.909 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr4_+_93444572 0.905 NM_001510
GRID2
glutamate receptor, ionotropic, delta 2
chr5_+_17270474 0.904 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr20_+_1822779 0.903 NM_001040022
SIRPA
signal-regulatory protein alpha
chrX_+_12066505 0.896 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr9_+_138341752 0.893 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr7_-_23476156 0.887


chr22_-_49348193 0.886 NM_001123225
C22orf41
chromosome 22 open reading frame 41
chr12_-_116890410 0.885 NM_173598
KSR2
kinase suppressor of ras 2
chrX_+_71047344 0.883 NM_001013627
NHSL2
NHS-like 2
chr17_-_20886680 0.883 NM_015276
USP22
ubiquitin specific peptidase 22
chr9_+_117955890 0.882 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr11_+_61352209 0.881 NM_004265
FADS2
fatty acid desaturase 2
chr15_+_65904994 0.880 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr2_+_48610567 0.877 NM_001198593
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr8_-_89408832 0.875 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr7_-_150604752 0.871 NM_001003802
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr14_-_22904239 0.869 EFS
embryonal Fyn-associated substrate
chr8_-_21702273 0.868 NM_001165038
NM_001165039
NM_001495
GFRA2


GDNF family receptor alpha 2


chr1_+_201711505 0.868 NM_002725
NM_201348
PRELP

proline/arginine-rich end leucine-rich repeat protein

chr2_-_152664056 0.865 CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr17_-_19231049 0.862 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr3_+_98016114 0.860 NM_001080448
EPHA6
EPH receptor A6
chr16_-_17472238 0.856 NM_022166
XYLT1
xylosyltransferase I
chr10_+_80672842 0.854 ZMIZ1
zinc finger, MIZ-type containing 1
chr3_-_189354510 0.850 LOC339929
hypothetical LOC339929
chr2_-_45090025 0.844 NM_016932
SIX2
SIX homeobox 2
chr6_+_17501589 0.843 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr16_+_54070302 0.843 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr1_+_18830086 0.842 NM_001135254
NM_002584
NM_013945
PAX7


paired box 7


chr20_+_1822943 0.833 SIRPA
signal-regulatory protein alpha
chr3_-_52418933 0.832 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr14_-_53493198 0.830 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr3_+_53504070 0.829 NM_000720
NM_001128839
NM_001128840
CACNA1D


calcium channel, voltage-dependent, L type, alpha 1D subunit


chr13_-_113066202 0.829 GRTP1
growth hormone regulated TBC protein 1
chr6_+_41714171 0.829 NM_005586
MDFI
MyoD family inhibitor
chr19_-_13478037 0.827 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr19_+_54786723 0.826 NM_020719
PRR12
proline rich 12
chr4_-_1097313 0.825 NM_001131034
NM_001193318
NM_194439
RNF212


ring finger protein 212


chr11_-_62445587 0.824 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr1_-_29321599 0.821 NM_001171868
TMEM200B
transmembrane protein 200B
chr12_+_52653176 0.820 NM_014212
HOXC11
homeobox C11
chr11_-_117528744 0.819 NM_001142348
NM_174934
SCN4B

sodium channel, voltage-gated, type IV, beta

chr12_-_43731148 0.816 NM_001004329
DBX2
developing brain homeobox 2
chr10_-_79067210 0.812 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_+_11009436 0.810 SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr20_-_4752067 0.809 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr19_+_44379440 0.808 NM_001001414
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr4_+_61749540 0.808 LPHN3
latrophilin 3
chr3_-_13896618 0.807 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr12_-_6355165 0.806 NM_001038
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr6_+_127481740 0.806 NM_032784
RSPO3
R-spondin 3 homolog (Xenopus laevis)
chr14_-_62581656 0.802 NM_139318
NM_172375
KCNH5

potassium voltage-gated channel, subfamily H (eag-related), member 5

chr19_-_51168396 0.800 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr4_+_134289893 0.799 NM_020815
NM_032961
PCDH10

protocadherin 10

chr12_-_6354650 0.798 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr20_-_17986520 0.797 NM_021220
OVOL2
ovo-like 2 (Drosophila)
chr12_-_6668880 0.796 NM_001039917
NM_001039919
NM_001039920
NM_001135734
ZNF384



zinc finger protein 384



chr19_-_60573552 0.796 NM_000641
IL11
interleukin 11
chr17_-_29930431 0.792 NM_207454
C17orf102
chromosome 17 open reading frame 102
chr2_-_237080830 0.789 NM_024726
IQCA1
IQ motif containing with AAA domain 1
chr18_+_17076166 0.787 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr20_+_19141282 0.787 NM_020689
SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr17_-_44047299 0.786 NM_024016
HOXB8
homeobox B8
chr13_+_49469138 0.786 NM_001007278
NM_005798
NM_052811
NM_213590
TRIM13



tripartite motif containing 13



chr6_-_33822659 0.786 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr5_-_168660293 0.785 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr5_-_92942680 0.781 FLJ42709
hypothetical LOC441094
chr12_-_6585785 0.780 CHD4
chromodomain helicase DNA binding protein 4
chr9_-_4289574 0.778 GLIS3
GLIS family zinc finger 3
chr5_-_172689111 0.778 NM_003714
STC2
stanniocalcin 2
chr4_-_46086218 0.775 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr4_+_145786622 0.773 NM_022475
HHIP
hedgehog interacting protein
chr1_-_194844299 0.773 KCNT2
potassium channel, subfamily T, member 2
chr11_-_45643711 0.770 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr18_-_26996742 0.763 NM_004948
NM_024421
DSC1

desmocollin 1

chr7_+_27248688 0.762 NM_001989
EVX1
even-skipped homeobox 1
chr10_+_119291945 0.759 NM_001165924
NM_004098
EMX2

empty spiracles homeobox 2

chr19_-_50964336 0.758 NM_175875
SIX5
SIX homeobox 5
chr9_-_4289915 0.751 GLIS3
GLIS family zinc finger 3
chr17_-_45427565 0.748 NM_005220
DLX3
distal-less homeobox 3
chr19_+_12996745 0.747 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr21_+_42946719 0.746 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr1_+_199426575 0.742 NM_001164586
IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr7_+_28415495 0.742 LOC401317
hypothetical LOC401317
chr11_+_17714070 0.740 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr11_-_132318741 0.738 OPCML
opioid binding protein/cell adhesion molecule-like
chr8_+_121206478 0.738 NM_021110
COL14A1
collagen, type XIV, alpha 1
chr5_-_9599157 0.736 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr10_+_102495327 0.732 NM_000278
NM_003987
NM_003988
NM_003989
NM_003990
PAX2




paired box 2




chr22_+_34266837 0.732


chr10_+_50488352 0.730 NM_003055
SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr6_+_37245860 0.728 NM_002648
PIM1
pim-1 oncogene
chr11_+_8059267 0.728 NM_177972
TUB
tubby homolog (mouse)
chr19_-_56204615 0.728 NM_012315
KLK9
kallikrein-related peptidase 9

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 2.41e-22 GO:0050789 regulation of biological process
1.14 3.07e-22 GO:0050794 regulation of cellular process
1.13 3.27e-22 GO:0065007 biological regulation
1.36 4.17e-19 GO:0007399 nervous system development
1.21 1.09e-16 GO:0007275 multicellular organismal development
1.19 3.07e-16 GO:0032502 developmental process
1.32 1.60e-15 GO:0009653 anatomical structure morphogenesis
1.22 4.28e-15 GO:0048731 system development
1.07 3.28e-14 GO:0009987 cellular process
1.20 6.16e-14 GO:0048856 anatomical structure development
1.22 1.21e-13 GO:0048518 positive regulation of biological process
1.23 1.27e-13 GO:0048522 positive regulation of cellular process
1.39 2.51e-13 GO:0022008 neurogenesis
1.23 1.30e-12 GO:0048519 negative regulation of biological process
1.24 1.80e-12 GO:0048523 negative regulation of cellular process
1.18 1.84e-12 GO:0031323 regulation of cellular metabolic process
1.24 3.58e-12 GO:0030154 cell differentiation
1.18 4.03e-12 GO:0080090 regulation of primary metabolic process
1.39 6.27e-12 GO:0048699 generation of neurons
1.23 2.99e-11 GO:0048869 cellular developmental process
1.42 5.67e-11 GO:0030182 neuron differentiation
1.16 8.16e-11 GO:0019222 regulation of metabolic process
1.16 2.78e-10 GO:0023052 signaling
1.19 3.40e-10 GO:0051171 regulation of nitrogen compound metabolic process
1.17 4.60e-10 GO:0060255 regulation of macromolecule metabolic process
1.33 6.25e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.19 1.89e-09 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19 1.89e-09 GO:0031326 regulation of cellular biosynthetic process
1.24 6.59e-09 GO:0023051 regulation of signaling
1.18 7.64e-09 GO:0009889 regulation of biosynthetic process
1.44 1.25e-08 GO:0007417 central nervous system development
1.39 1.33e-08 GO:0051254 positive regulation of RNA metabolic process
1.45 1.38e-08 GO:0000904 cell morphogenesis involved in differentiation
1.35 1.64e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.22 1.99e-08 GO:0048513 organ development
1.25 5.52e-08 GO:0009966 regulation of signal transduction
1.19 5.61e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.37 5.69e-08 GO:0010628 positive regulation of gene expression
1.52 7.52e-08 GO:0007389 pattern specification process
1.35 1.00e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 1.04e-07 GO:0031324 negative regulation of cellular metabolic process
1.30 1.12e-07 GO:0009892 negative regulation of metabolic process
1.38 1.28e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.62 1.33e-07 GO:0003002 regionalization
1.39 1.45e-07 GO:0009887 organ morphogenesis
1.39 1.79e-07 GO:0048666 neuron development
1.18 1.96e-07 GO:0010468 regulation of gene expression
1.36 2.01e-07 GO:0031327 negative regulation of cellular biosynthetic process
1.15 2.44e-07 GO:0007165 signal transduction
1.18 2.79e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.30 2.89e-07 GO:0048468 cell development
1.35 4.25e-07 GO:0009890 negative regulation of biosynthetic process
1.30 4.55e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.75 5.32e-07 GO:0045165 cell fate commitment
1.37 5.62e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.18 5.79e-07 GO:0051252 regulation of RNA metabolic process
1.42 7.17e-07 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.37 9.08e-07 GO:0000902 cell morphogenesis
1.30 1.06e-06 GO:0050793 regulation of developmental process
1.41 1.17e-06 GO:0031175 neuron projection development
1.36 1.17e-06 GO:0032989 cellular component morphogenesis
1.35 1.39e-06 GO:0030030 cell projection organization
1.35 1.49e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.31 1.52e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.42 2.52e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.25 2.98e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.25 3.28e-06 GO:0031325 positive regulation of cellular metabolic process
1.69 3.34e-06 GO:0009952 anterior/posterior pattern formation
1.35 3.56e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.32 3.90e-06 GO:2000026 regulation of multicellular organismal development
1.30 4.38e-06 GO:0009891 positive regulation of biosynthetic process
1.24 4.51e-06 GO:0009893 positive regulation of metabolic process
1.46 5.43e-06 GO:0007420 brain development
1.30 6.09e-06 GO:0051128 regulation of cellular component organization
1.35 6.49e-06 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19 6.66e-06 GO:0048583 regulation of response to stimulus
1.29 7.07e-06 GO:0006351 transcription, DNA-dependent
1.35 1.18e-05 GO:0010629 negative regulation of gene expression
1.17 1.25e-05 GO:0006355 regulation of transcription, DNA-dependent
1.10 1.26e-05 GO:0043170 macromolecule metabolic process
1.40 1.60e-05 GO:0048812 neuron projection morphogenesis
1.31 1.65e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.32 1.67e-05 GO:0045595 regulation of cell differentiation
1.12 1.78e-05 GO:0051716 cellular response to stimulus
1.36 1.79e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.32 1.93e-05 GO:0009790 embryo development
1.36 1.95e-05 GO:0051253 negative regulation of RNA metabolic process
1.37 1.99e-05 GO:0048858 cell projection morphogenesis
1.40 3.20e-05 GO:0007409 axonogenesis
1.22 3.71e-05 GO:0051239 regulation of multicellular organismal process
1.43 3.98e-05 GO:0048598 embryonic morphogenesis
1.36 5.06e-05 GO:0032990 cell part morphogenesis
1.30 1.92e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.44 2.95e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.38 3.85e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.42 5.10e-04 GO:0060284 regulation of cell development
1.49 5.95e-04 GO:0051129 negative regulation of cellular component organization
1.90 6.58e-04 GO:0009953 dorsal/ventral pattern formation
1.24 7.12e-04 GO:0032774 RNA biosynthetic process
1.48 1.12e-03 GO:0048568 embryonic organ development
1.40 1.30e-03 GO:0007411 axon guidance
1.22 1.33e-03 GO:0010646 regulation of cell communication
1.43 1.94e-03 GO:0035295 tube development
1.10 2.06e-03 GO:0044260 cellular macromolecule metabolic process
1.11 2.38e-03 GO:0016043 cellular component organization
1.31 2.43e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.13 2.66e-03 GO:0071842 cellular component organization at cellular level
1.07 2.81e-03 GO:0044238 primary metabolic process
1.36 3.89e-03 GO:0009792 embryo development ending in birth or egg hatching
1.11 4.37e-03 GO:0071840 cellular component organization or biogenesis
2.37 4.45e-03 GO:0071300 cellular response to retinoic acid
1.33 4.48e-03 GO:0032583 regulation of gene-specific transcription
1.36 4.69e-03 GO:0043009 chordate embryonic development
2.21 5.29e-03 GO:0071295 cellular response to vitamin
1.32 5.49e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.36 5.65e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.39 6.96e-03 GO:0048729 tissue morphogenesis
1.79 7.97e-03 GO:2000027 regulation of organ morphogenesis
1.58 9.27e-03 GO:0060537 muscle tissue development
2.05 1.06e-02 GO:0001656 metanephros development
1.21 1.15e-02 GO:0007154 cell communication
1.37 1.33e-02 GO:0001501 skeletal system development
1.12 1.39e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.21 1.39e-02 GO:0032879 regulation of localization
1.37 1.40e-02 GO:0051093 negative regulation of developmental process
1.22 1.44e-02 GO:0009888 tissue development
2.28 1.54e-02 GO:0071299 cellular response to vitamin A
1.63 1.68e-02 GO:0001822 kidney development
1.06 1.84e-02 GO:0008152 metabolic process
1.30 1.96e-02 GO:0072358 cardiovascular system development
1.30 1.96e-02 GO:0072359 circulatory system development
1.40 2.04e-02 GO:0001568 blood vessel development
1.31 2.04e-02 GO:0051094 positive regulation of developmental process
2.03 2.18e-02 GO:0031670 cellular response to nutrient
1.58 2.24e-02 GO:0014706 striated muscle tissue development
1.46 2.46e-02 GO:0007517 muscle organ development
1.51 2.80e-02 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.92 2.81e-02 GO:0021510 spinal cord development
1.20 2.88e-02 GO:0042127 regulation of cell proliferation
1.60 3.61e-02 GO:0072001 renal system development
1.45 3.64e-02 GO:0032582 negative regulation of gene-specific transcription
1.38 4.12e-02 GO:0061061 muscle structure development
1.47 4.23e-02 GO:0030900 forebrain development
1.50 4.28e-02 GO:0048562 embryonic organ morphogenesis
1.38 4.47e-02 GO:0045596 negative regulation of cell differentiation
1.77 4.98e-02 GO:0032526 response to retinoic acid

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 1.46e-09 GO:0044424 intracellular part
1.05 1.92e-08 GO:0005622 intracellular
1.07 1.11e-07 GO:0005737 cytoplasm
1.36 1.17e-04 GO:0043005 neuron projection
1.08 2.49e-04 GO:0005634 nucleus
1.05 6.77e-04 GO:0043226 organelle
1.05 8.41e-04 GO:0043229 intracellular organelle
1.05 9.09e-04 GO:0043231 intracellular membrane-bounded organelle
1.05 9.37e-04 GO:0043227 membrane-bounded organelle
1.32 1.82e-03 GO:0045202 synapse
1.21 4.30e-03 GO:0042995 cell projection
1.25 4.65e-03 GO:0030054 cell junction
1.02 8.49e-03 GO:0044464 cell part
1.02 9.12e-03 GO:0005623 cell
1.60 1.06e-02 GO:0005925 focal adhesion
1.44 1.35e-02 GO:0030424 axon
1.38 1.35e-02 GO:0016323 basolateral plasma membrane
1.54 2.60e-02 GO:0030055 cell-substrate junction
1.41 2.73e-02 GO:0030425 dendrite
1.55 3.10e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 6.24e-16 GO:0005515 protein binding
1.47 3.56e-15 GO:0043565 sequence-specific DNA binding
1.36 1.59e-13 GO:0001071 nucleic acid binding transcription factor activity
1.36 1.59e-13 GO:0003700 sequence-specific DNA binding transcription factor activity
1.35 1.07e-12 GO:0030528 transcription regulator activity
1.06 9.25e-11 GO:0005488 binding
1.36 4.72e-05 GO:0019904 protein domain specific binding
1.50 3.36e-04 GO:0000975 regulatory region DNA binding
1.50 3.36e-04 GO:0001067 regulatory region nucleic acid binding
1.50 3.36e-04 GO:0044212 transcription regulatory region DNA binding
1.50 4.84e-04 GO:0010843 promoter binding
1.39 1.51e-03 GO:0008134 transcription factor binding
1.13 3.77e-03 GO:0003677 DNA binding
1.36 4.13e-03 GO:0016563 transcription activator activity
1.24 8.12e-03 GO:0046983 protein dimerization activity
1.21 2.64e-02 GO:0019899 enzyme binding
1.19 3.16e-02 GO:0030234 enzyme regulator activity
1.29 3.59e-02 GO:0000988 protein binding transcription factor activity
1.29 3.59e-02 GO:0000989 transcription factor binding transcription factor activity
1.29 4.71e-02 GO:0003712 transcription cofactor activity