Motif ID: PAX4.p2

Z-value: 1.459


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
PAX4 5078 paired box 4



Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_58736897 2.480 NM_001039396
MPEG1
macrophage expressed 1
chr11_+_1830763 2.353 NM_002339
LSP1
lymphocyte-specific protein 1
chr19_+_59833719 2.333 NM_001081638
NM_001081639
NM_001081637
LILRB1


leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1


chr6_+_31662454 2.149 NM_205837
LST1
leukocyte specific transcript 1
chr19_+_59796858 2.117 NM_006863
LILRA1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr11_-_67174684 2.106 NM_080658
ACY3
aspartoacylase (aminocyclase) 3
chr3_+_51870684 2.090 NM_203424
IQCF2
IQ motif containing F2
chr17_+_69781980 2.049 NM_001172810
NM_023036
DNAI2

dynein, axonemal, intermediate chain 2

chr6_+_31661934 2.031 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr17_+_22823151 1.865 NM_014238
KSR1
kinase suppressor of ras 1
chr8_-_21827057 1.843 NM_003974
DOK2
docking protein 2, 56kDa
chr2_-_215711313 1.628 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr19_-_59476734 1.605 NM_001080978
NM_005874
LILRB2

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2

chr20_+_61654816 1.601 NM_024059
C20orf195
chromosome 20 open reading frame 195
chr1_-_30977931 1.598 LAPTM5
lysosomal protein transmembrane 5
chr1_+_151147646 1.581 NM_005547
IVL
involucrin
chr6_-_137536412 1.574 NM_052962
NM_181309
NM_181310
IL22RA2


interleukin 22 receptor, alpha 2


chr7_+_133884388 1.502 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr1_+_20353284 1.489


chr2_-_64944214 1.470


chr7_+_134567270 1.391 NM_182489
STRA8
stimulated by retinoic acid gene 8 homolog (mouse)
chr10_-_85921703 1.377 LOC642934
hypothetical LOC642934
chr6_+_134800533 1.355 LOC154092
hypothetical LOC154092
chr19_-_46504831 1.352


chr19_-_16111594 1.285


chr6_+_31690957 1.276 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr22_-_16080265 1.244 CECR1
cat eye syndrome chromosome region, candidate 1
chrX_+_154880439 1.213 NM_002186
IL9R
interleukin 9 receptor
chr12_+_115481568 1.144 NM_001085481
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr1_-_20318578 1.138 NM_012400
PLA2G2D
phospholipase A2, group IID
chr4_-_40211324 1.108 RBM47
RNA binding motif protein 47
chr1_-_25164061 1.079 NM_001031680
RUNX3
runt-related transcription factor 3
chr7_-_86433139 1.053 NM_152748
KIAA1324L
KIAA1324-like
chr14_+_66901237 1.045 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr19_-_16111695 1.040


chr1_+_15675182 1.027 NM_015849
CELA2B
chymotrypsin-like elastase family, member 2B
chr4_+_39874921 1.008 NM_004310
RHOH
ras homolog gene family, member H
chr6_+_32515596 0.991 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr8_+_39890484 0.991 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr1_-_158948176 0.991 NM_001778
CD48
CD48 molecule
chr15_+_64481270 0.956 MAP2K1
mitogen-activated protein kinase kinase 1
chr3_+_123779122 0.948 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr3_+_46258875 0.948 NM_001164680
NM_001837
NM_178328
NM_178329
CCR3



chemokine (C-C motif) receptor 3



chr12_-_6615348 0.921 NM_020400
LPAR5
lysophosphatidic acid receptor 5
chr19_+_10820105 0.920 NM_001136482
C19orf38
chromosome 19 open reading frame 38
chr7_-_135263737 0.888 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chrX_+_71280758 0.882 NM_207422
FLJ44635
TPT1-like protein
chr4_+_38860418 0.874 NM_025132
WDR19
WD repeat domain 19
chr3_+_190831909 0.873 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr7_+_77307382 0.871 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr1_+_15655809 0.868 NM_033440
CELA2A
chymotrypsin-like elastase family, member 2A
chr1_+_12046020 0.856 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr16_+_49288550 0.848 NM_022162
NOD2
nucleotide-binding oligomerization domain containing 2
chr11_+_10439253 0.836 NM_001172430
AMPD3
adenosine monophosphate deaminase 3
chr17_-_44154878 0.811 NM_032391
PRAC
prostate cancer susceptibility candidate
chr4_-_40212670 0.751 NM_019027
RBM47
RNA binding motif protein 47
chr18_+_59726183 0.737 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr6_+_135558744 0.736 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr4_-_176970407 0.705 GPM6A
glycoprotein M6A
chr1_-_26571812 0.703 NM_001114759
NM_173574
ZNF683

zinc finger protein 683

chr9_-_5175601 0.684 NM_007179
INSL6
insulin-like 6
chr2_-_136590210 0.681 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr10_+_35466715 0.680 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr18_-_51406841 0.675 NM_001083962
NM_003199
TCF4

transcription factor 4

chr2_+_104837004 0.664


chr20_+_42644633 0.663 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr11_-_58368555 0.663 NM_145016
GLYATL2
glycine-N-acyltransferase-like 2
chr4_+_82171142 0.640 NM_001201
BMP3
bone morphogenetic protein 3
chr20_-_23010786 0.630 CD93
CD93 molecule
chr14_-_49629110 0.626 NM_001014830
C14orf183
chromosome 14 open reading frame 183
chr16_+_31273969 0.625 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr14_-_105542441 0.609 IGLJ3
IGHA1
IGHG1
IGHM
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr1_-_39910296 0.607 NM_032526
NT5C1A
5'-nucleotidase, cytosolic IA
chr17_+_28342994 0.599 NM_173847
SPACA3
sperm acrosome associated 3
chr5_-_95774444 0.593 NM_001177876
PCSK1
proprotein convertase subtilisin/kexin type 1
chr4_-_176970372 0.592 GPM6A
glycoprotein M6A
chr19_-_60528480 0.590 NM_001085488
TMEM150B
transmembrane protein 150B
chr11_+_20341806 0.587 NM_006410
NM_001098521
HTATIP2

HIV-1 Tat interactive protein 2, 30kDa

chr10_+_114699953 0.583 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr9_-_122716670 0.579 NM_001190947
TRAF1
TNF receptor-associated factor 1
chr1_-_208024491 0.574 NM_152485
C1orf74
chromosome 1 open reading frame 74
chr15_-_75135496 0.558 TSPAN3
tetraspanin 3
chr11_-_62231445 0.548 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_-_77730573 0.547 NM_012296
GAB2
GRB2-associated binding protein 2
chr6_-_32665409 0.545 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr10_-_49483002 0.539 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr2_+_218833982 0.534 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr18_-_51406359 0.533 TCF4
transcription factor 4
chr1_+_151897817 0.527 SNAPIN
SNAP-associated protein
chr3_+_188222337 0.522 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr5_+_42792676 0.515 NM_001134848
CCDC152
coiled-coil domain containing 152
chr8_-_134156353 0.503 SLA
Src-like-adaptor
chr20_+_43764068 0.497 NM_172005
WFDC13
WAP four-disulfide core domain 13
chr4_+_123311207 0.497 NM_015312
KIAA1109
KIAA1109
chrX_-_134257624 0.497 NM_001185063
NM_007131
ZNF75D

zinc finger protein 75D

chr11_+_20341900 0.494 NM_001098522
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr11_-_18566758 0.491 NM_001040697
NM_018314
UEVLD

UEV and lactate/malate dehyrogenase domains

chr19_+_10077898 0.490 NM_020230
NM_001040664
NM_001198690
PPAN
PPAN-P2RY11

peter pan homolog (Drosophila)
PPAN-P2RY11 readthrough

chrX_+_65300803 0.487 NM_001130860
NM_014799
HEPH

hephaestin

chr21_+_37713076 0.482 NM_130436
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr3_-_195670256 0.481 NM_024524
ATP13A3
ATPase type 13A3
chr1_+_151897768 0.475 NM_012437
SNAPIN
SNAP-associated protein
chr11_-_62231358 0.470 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr19_-_10281220 0.467 NM_001103167
ZGLP1
zinc finger, GATA-like protein 1
chr6_-_31668476 0.466 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3


chrX_-_47941142 0.465 NM_021015
NM_175723
SSX5

synovial sarcoma, X breakpoint 5

chr16_+_70437394 0.465 NM_001137675
ATXN1L
ataxin 1-like
chr19_+_45973139 0.462 NM_006533
MIA
melanoma inhibitory activity
chr7_+_142723340 0.461 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr11_-_62231386 0.460 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr7_+_26298136 0.459 SNX10
sorting nexin 10
chr1_-_158759606 0.455 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr11_+_64564948 0.454 NM_013299
SAC3D1
SAC3 domain containing 1
chr3_+_112743615 0.449 NM_005816
NM_198196
CD96

CD96 molecule

chr20_-_30703219 0.446 NM_182584
C20orf203
chromosome 20 open reading frame 203
chr11_+_64564971 0.444 SAC3D1
SAC3 domain containing 1
chr6_-_36412562 0.443 NM_001010903
C6orf222
chromosome 6 open reading frame 222
chr12_-_112058403 0.441 NM_001193520
NM_004658
RASAL1

RAS protein activator like 1 (GAP1 like)

chr21_-_32573195 0.439 NM_018944
MIS18A
MIS18 kinetochore protein homolog A (S. pombe)
chr16_-_727889 0.437 NARFL
nuclear prelamin A recognition factor-like
chr1_-_180626804 0.434 GLUL
glutamate-ammonia ligase
chr22_-_22426551 0.433 NM_013378
VPREB3
pre-B lymphocyte 3
chr12_+_120055013 0.433 NM_002562
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr7_+_18296569 0.430 HDAC9
histone deacetylase 9
chr17_+_69833945 0.428 NM_153209
KIF19
kinesin family member 19
chr12_-_112326037 0.427 NM_006843
SDS
serine dehydratase
chr10_-_35419486 0.427 NM_001198777
CUL2
cullin 2
chr18_+_70352649 0.426 NM_032649
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr1_+_170656450 0.425 NM_139240
C1orf105
chromosome 1 open reading frame 105
chr19_+_40849554 0.416 NM_007000
UPK1A
uroplakin 1A
chr12_+_51783540 0.415 NM_003578
SOAT2
sterol O-acyltransferase 2
chr19_+_54583286 0.411 NM_144688
CCDC155
coiled-coil domain containing 155
chr6_+_32713160 0.411 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr7_+_106292975 0.411 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr19_-_7718396 0.409 NM_001144893
NM_001144894
NM_001144895
NM_001144896
NM_001144897
NM_001144899
NM_021155
CD209






CD209 molecule






chr5_-_88004891 0.408 LOC645323
hypothetical LOC645323
chr18_+_3439972 0.407 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1


chr19_+_59866237 0.402 LILRB4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
chr4_-_176970895 0.401 GPM6A
glycoprotein M6A
chr14_-_94012266 0.398 NM_001042518
NM_175739
SERPINA9

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9

chr11_+_20341835 0.394 NM_001098520
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr16_+_22432344 0.391 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr12_+_74160779 0.389 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr19_-_56696799 0.388 NM_053003
SIGLEC12
sialic acid binding Ig-like lectin 12
chr11_+_63030131 0.388 LGALS12
lectin, galactoside-binding, soluble, 12
chr1_-_84099261 0.386


chr3_+_120781212 0.384 NM_001125
ADPRH
ADP-ribosylarginine hydrolase
chr11_-_87548199 0.383 NM_022337
RAB38
RAB38, member RAS oncogene family
chr5_+_150137700 0.382 NM_032947
C5orf62
chromosome 5 open reading frame 62
chr7_-_99594211 0.381 NM_018275
C7orf43
chromosome 7 open reading frame 43
chr16_+_28850760 0.380 NM_001178098
NM_001770
CD19

CD19 molecule

chr11_-_62231242 0.378 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr18_+_70352779 0.378 CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr19_+_46992361 0.375 NM_001815
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr4_+_47181987 0.374 NM_020453
ATP10D
ATPase, class V, type 10D
chr5_+_94752803 0.374 NM_152548
FAM81B
family with sequence similarity 81, member B
chrX_-_154216929 0.373 NM_001289
CLIC2
chloride intracellular channel 2
chr6_-_149847718 0.372 ZC3H12D
zinc finger CCCH-type containing 12D
chr12_-_119172339 0.371 NM_025157
PXN
paxillin
chr3_+_195887903 0.367 NM_153690
FAM43A
family with sequence similarity 43, member A
chr1_+_242882972 0.363 NM_016076
PPPDE1
PPPDE peptidase domain containing 1
chr12_+_69148120 0.356


chr7_+_110518297 0.355 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr12_+_51783554 0.353 SOAT2
sterol O-acyltransferase 2
chr4_-_140280031 0.353 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr12_+_52126131 0.352 PRR13
proline rich 13
chr7_+_72486044 0.351 NM_003508
FZD9
frizzled homolog 9 (Drosophila)
chr12_-_93568336 0.351 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr12_-_8584658 0.349 NM_014358
CLEC4E
C-type lectin domain family 4, member E
chr12_+_10256682 0.347 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr7_+_5609416 0.346 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr9_-_129707392 0.340 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr12_-_27126721 0.339 NM_001080406
C12orf71
chromosome 12 open reading frame 71
chr7_-_124192265 0.338 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr7_+_115926679 0.338 NM_001233
NM_198212
CAV2

caveolin 2

chr7_-_105106844 0.337 NM_138495
ATXN7L1
ataxin 7-like 1
chr1_+_93830106 0.336 LOC100129046
hypothetical LOC100129046
chr11_+_36379122 0.331 NM_001160169
PRR5L
proline rich 5 like
chr14_+_23852152 0.325 NM_181657
LTB4R
leukotriene B4 receptor
chr1_-_158815850 0.323 CD84
CD84 molecule
chr19_+_56452775 0.323 NM_173635
C19orf75
chromosome 19 open reading frame 75
chrX_+_128942435 0.323


chr10_+_74323344 0.320 NM_152635
OIT3
oncoprotein induced transcript 3
chr18_-_21184824 0.320


chr11_-_64301807 0.317 NM_001178031
SF1
splicing factor 1
chr1_+_26516967 0.316 NM_001803
CD52
CD52 molecule
chr14_-_105523735 0.312 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_129868059 0.310 NM_018718
TSGA14
testis specific, 14
chr19_-_6284561 0.310 NM_133492
ACER1
alkaline ceramidase 1
chr2_+_134728299 0.309 NM_002410
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr3_-_9896933 0.304 CIDEC
cell death-inducing DFFA-like effector c
chr6_+_30002084 0.301


chr7_+_75892187 0.300 NM_001110354
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr19_+_14913298 0.298 NM_012377
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr6_+_158990982 0.298 NM_001009991
SYTL3
synaptotagmin-like 3
chr12_-_112057650 0.293 NM_001193521
RASAL1
RAS protein activator like 1 (GAP1 like)
chr12_-_101398503 0.293 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr7_+_150013716 0.291 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr14_+_20319049 0.291 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr1_+_242883057 0.289 PPPDE1
PPPDE peptidase domain containing 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.