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• Activity deltas table
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Motif ID: PAX6.p2

Z-value: 0.807

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_165564904	1.716	NM_001198783	POU2F1	POU class 2 homeobox 1
chr1_+_165565006	1.681		POU2F1	POU class 2 homeobox 1
chr6_-_131333173	1.671		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr10_+_35934343	1.087	NM_153368	GJD4	gap junction protein, delta 4, 40.1kDa
chr5_-_135259403	1.069	NM_000590	IL9	interleukin 9
chr6_-_42270671	0.872	NM_002098	GUCA1B	guanylate cyclase activator 1B (retina)
chr16_+_70646008	0.763	NM_001126102 NM_005143	HP	haptoglobin
chr9_+_102380156	0.669	NM_001018116	MURC	muscle-related coiled-coil protein
chr15_-_48192804	0.610		ATP8B4	ATPase, class I, type 8B, member 4
chr16_+_70654625	0.596	NM_020995	HPR	haptoglobin-related protein
chr2_+_39000007	0.593	NM_001145451	ARHGEF33	Rho guanine nucleotide exchange factor (GEF) 33
chr15_+_49760841	0.526	NM_001165257 NM_013243	SCG3	secretogranin III
chr1_-_31117948	0.506		SDC3	syndecan 3
chr5_-_142057692	0.472	NM_001144934 NM_001144935	FGF1	fibroblast growth factor 1 (acidic)
chr8_+_39911630	0.448	NM_194294	IDO2	indoleamine 2,3-dioxygenase 2
chr3_-_15538164	0.438	NM_005677 NM_080539	COLQ	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr8_-_21827057	0.415	NM_003974	DOK2	docking protein 2, 56kDa
chr2_+_170074457	0.395	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chrX_-_15242589	0.348	NM_001012428	ASB11	ankyrin repeat and SOCS box containing 11
chr4_-_174557191	0.343	NM_007281	SCRG1	stimulator of chondrogenesis 1
chr15_+_27001131	0.339	NM_001130414 NM_005503	APBA2	amyloid beta (A4) precursor protein-binding, family A, member 2
chr8_+_21972804	0.329		EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr4_-_26100986	0.321	NM_000730	CCKAR	cholecystokinin A receptor
chr19_-_56825400	0.321	NM_003830	SIGLEC5	sialic acid binding Ig-like lectin 5
chr11_+_4859624	0.310	NM_001004759	OR51T1	olfactory receptor, family 51, subfamily T, member 1
chr2_+_178893216	0.290	NM_145739	OSBPL6	oxysterol binding protein-like 6
chr3_-_120861959	0.287	NM_022135	POPDC2	popeye domain containing 2
chr4_+_114190233	0.264	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr19_+_56990222	0.261	NM_002030	FPR3	formyl peptide receptor 3
chr1_+_113038202	0.260		MOV10	Mov10, Moloney leukemia virus 10, homolog (mouse)
chr11_+_123600553	0.257	NM_001007249	OR8G2	olfactory receptor, family 8, subfamily G, member 2
chrX_-_123925343	0.256	NM_001163278 NM_001163279 NM_014253	ODZ1	odz, odd Oz/ten-m homolog 1(Drosophila)
chr16_-_11282595	0.255	NM_002761	PRM1	protamine 1
chr6_-_10520264	0.253		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_-_27524744	0.253	NM_203339	CLU	clusterin
chr2_-_157890400	0.243	NM_020711	ERMN	ermin, ERM-like protein
chr22_+_24468168	0.238		MYO18B	myosin XVIIIB
chr17_-_1195096	0.228		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr12_+_108035424	0.225
chrX_-_130251068	0.223	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chr9_-_94206648	0.220	NM_014057 NM_033014	OGN	osteoglycin
chr1_+_145841569	0.219	NM_005267	GJA8	gap junction protein, alpha 8, 50kDa
chr12_-_68379331	0.216	NM_032735	BEST3	bestrophin 3
chr5_+_40945315	0.205	NM_000587	C7	complement component 7
chr22_+_38652555	0.200		GRAP2	GRB2-related adaptor protein 2
chr1_+_108794426	0.199	NM_001143987 NM_001143988	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr1_+_51855133	0.197	NM_024586 NM_148906 NM_148908 NM_148909	OSBPL9	oxysterol binding protein-like 9
chrX_-_65176564	0.195	NM_001100431 NM_001184830 NM_001184831 NM_007268	VSIG4	V-set and immunoglobulin domain containing 4
chr11_-_5178505	0.187	NM_001004760	OR51V1	olfactory receptor, family 51, subfamily V, member 1
chr11_-_117253354	0.185	NM_001164831	FXYD6	FXYD domain containing ion transport regulator 6
chr2_-_171631728	0.184	NM_001136555	TLK1	tousled-like kinase 1
chr1_-_209732881	0.183	NM_001164688 NM_183059	RD3	retinal degeneration 3
chr5_+_180399871	0.182		BTNL9	butyrophilin-like 9
chr6_+_25760352	0.180	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr3_-_196792059	0.179		APOD	apolipoprotein D
chr12_-_131725848	0.179		POLE	polymerase (DNA directed), epsilon
chr11_+_19328846	0.179	NM_001111018	NAV2	neuron navigator 2
chr5_+_42792676	0.176	NM_001134848	CCDC152	coiled-coil domain containing 152
chr1_+_61697209	0.173		NFIA	nuclear factor I/A
chr20_+_31713750	0.172	NM_080825	C20orf144	chromosome 20 open reading frame 144
chr19_+_15920817	0.170	NM_001004465	OR10H4	olfactory receptor, family 10, subfamily H, member 4
chr1_+_51855343	0.162		OSBPL9	oxysterol binding protein-like 9
chr5_+_180399830	0.162	NM_152547	BTNL9	butyrophilin-like 9
chr20_-_45360903	0.156		ZMYND8	zinc finger, MYND-type containing 8
chrX_-_130250880	0.152		IGSF1	immunoglobulin superfamily, member 1
chr19_+_59941785	0.148	NM_015868	KIR2DS2 KIR2DL3	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
chr7_-_26198673	0.146		HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1
chr5_+_40945244	0.146		C7	complement component 7
chr17_-_36276987	0.144	NM_000223	KRT12	keratin 12
chr8_-_27525084	0.144	NM_001171138	CLU	clusterin
chr14_+_28311740	0.144		C14orf23	chromosome 14 open reading frame 23
chr8_-_62764839	0.143	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr11_+_76561471	0.141		MYO7A	myosin VIIA
chrX_-_106336199	0.141	NM_017681	NUP62CL	nucleoporin 62kDa C-terminal like
chr16_-_46823682	0.139	NM_033151	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chrX_-_135783496	0.138
chr15_+_63124760	0.135	NM_178859	OSTBETA	organic solute transporter beta
chr6_-_10520592	0.130	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chrX_+_48127911	0.130	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chr14_-_20694023	0.129	NM_001004731	OR5AU1	olfactory receptor, family 5, subfamily AU, member 1
chr3_-_129668780	0.129	NM_153330	DNAJB8	DnaJ (Hsp40) homolog, subfamily B, member 8
chr1_-_12830728	0.127	NM_001146181	HNRNPCL1 LOC649330	heterogeneous nuclear ribonucleoprotein C-like 1 heterogeneous nuclear ribonucleoprotein C-like
chr17_-_36294962	0.124	NM_019010	KRT20	keratin 20
chr3_+_134978615	0.122		TF	transferrin
chr12_+_55201854	0.118	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr11_+_119862014	0.118		ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12
chr22_-_48865907	0.117	NM_139202	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr5_-_169657312	0.114		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr6_-_28591542	0.112	NM_182701	GPX6	glutathione peroxidase 6 (olfactory)
chr3_+_16949585	0.112	NM_015184	PLCL2	phospholipase C-like 2
chr1_+_207944807	0.111	NM_005525	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr17_-_8602601	0.110	NM_001128076	SPDYE4	speedy homolog E4 (Xenopus laevis)
chr10_-_7699192	0.108		ITIH5	inter-alpha (globulin) inhibitor H5
chr1_-_246804680	0.104	NM_001001821	OR2T34	olfactory receptor, family 2, subfamily T, member 34
chr11_-_95715976	0.101	NM_032427	MAML2	mastermind-like 2 (Drosophila)
chr1_+_87153025	0.096		HS2ST1	heparan sulfate 2-O-sulfotransferase 1
chr5_-_79982584	0.095	NM_001190470	MTRNR2L2	MT-RNR2-like 2
chr6_+_155579788	0.095	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chrX_-_76823813	0.094
chr4_+_187385618	0.094	NM_000892	KLKB1	kallikrein B, plasma (Fletcher factor) 1
chr16_+_68705029	0.093	NM_017990	PDPR	pyruvate dehydrogenase phosphatase regulatory subunit
chr5_-_94250357	0.092		MCTP1	multiple C2 domains, transmembrane 1
chr9_-_139262009	0.092	NM_001001710	FAM166A	family with sequence similarity 166, member A
chr7_-_107930170	0.091		PNPLA8	patatin-like phospholipase domain containing 8
chr10_+_18280773	0.091	NM_001145195 NM_152725	SLC39A12	solute carrier family 39 (zinc transporter), member 12
chrX_-_13745134	0.088		GPM6B	glycoprotein M6B
chr2_+_62787534	0.086	NM_001142614	EHBP1	EH domain binding protein 1
chr2_-_133256097	0.086		NCKAP5	NCK-associated protein 5
chrX_-_52700674	0.084	NM_173358	SSX7	synovial sarcoma, X breakpoint 7
chr10_+_114033403	0.081	NM_058222	TECTB	tectorin beta
chr10_-_45350804	0.078	NM_001002266	MARCH8	membrane-associated ring finger (C3HC4) 8
chr11_+_117680504	0.075	NM_000733	CD3E	CD3e molecule, epsilon (CD3-TCR complex)
chr5_+_121493113	0.074	NM_207317	ZNF474	zinc finger protein 474
chr1_+_97033103	0.072
chr13_+_52500830	0.069	NM_006418	OLFM4	olfactomedin 4
chrX_+_49718954	0.064	NM_000084	CLCN5	chloride channel 5
chr3_-_148605996	0.063	NM_001168379	ZIC4	Zic family member 4
chr17_-_31831093	0.061	NM_001123392 NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3H TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3H TBC1 domain family, member 3F
chr8_+_7340777	0.060	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chr1_-_108588186	0.059	NM_001143989	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chrX_+_52797004	0.058	NM_003147 NM_175698 NM_001164417	SSX2 SSX2B	synovial sarcoma, X breakpoint 2 synovial sarcoma, X breakpoint 2B
chr6_-_134415311	0.057	NM_145176	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12
chr8_-_7710547	0.054	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chr15_+_43331719	0.047	NM_004212	SLC28A2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chrX_-_13744933	0.044		GPM6B	glycoprotein M6B
chr12_+_9925354	0.044	NM_001190765	KLRF2	killer cell lectin-like receptor subfamily F, member 2
chr1_+_202033273	0.043	NM_001174108	ZBED6	zinc finger, BED-type containing 6
chr20_-_32877029	0.042	NM_014071	NCOA6	nuclear receptor coactivator 6
chr15_-_23204887	0.042	NM_000462	UBE3A	ubiquitin protein ligase E3A
chr17_-_31616071	0.039	NM_001001418 NM_032258	TBC1D3B TBC1D3C TBC1D3G TBC1D3F	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3F
chr3_-_109730858	0.038	NM_014981	MYH15	myosin, heavy chain 15
chr19_+_54299686	0.038		SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)
chr3_-_14558591	0.038	NM_001080423	GRIP2	glutamate receptor interacting protein 2
chr10_+_102212787	0.037	NM_003393	WNT8B	wingless-type MMTV integration site family, member 8B
chr2_-_215951161	0.037		FN1	fibronectin 1
chr5_+_140742585	0.035	NM_018920 NM_032087	PCDHGA7	protocadherin gamma subfamily A, 7
chr4_+_100714995	0.033		MTTP	microsomal triglyceride transfer protein
chr5_-_58918031	0.033	NM_006203	PDE4D	phosphodiesterase 4D, cAMP-specific
chr12_+_119224506	0.033	NM_012240	SIRT4	sirtuin 4
chr3_+_122769467	0.032	NM_001012659	ARGFX	arginine-fifty homeobox
chrX_-_13745108	0.032		GPM6B	glycoprotein M6B
chr21_-_30855478	0.031	NM_181614	KRTAP19-7	keratin associated protein 19-7
chr20_+_18070867	0.030	NM_020536	CSRP2BP	CSRP2 binding protein
chr17_-_34209671	0.030	NM_003559	PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr1_+_148747208	0.030		ECM1	extracellular matrix protein 1
chr6_+_101953581	0.029	NM_001166247 NM_021956 NM_175768	GRIK2	glutamate receptor, ionotropic, kainate 2
chr6_+_101953389	0.029		GRIK2	glutamate receptor, ionotropic, kainate 2
chr3_+_153499883	0.027	NM_207293 NM_207294 NM_207295 NM_207296 NM_207297	MBNL1	muscleblind-like (Drosophila)
chr12_+_103206625	0.026		TXNRD1	thioredoxin reductase 1
chr3_+_134601479	0.025	NM_003571	BFSP2	beaded filament structural protein 2, phakinin
chr16_-_71650034	0.025	NM_001164766	ZFHX3	zinc finger homeobox 3
chr7_+_22733290	0.024	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chr6_+_167624792	0.024	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chrX_+_144716619	0.023	NM_004709	CXorf1	chromosome X open reading frame 1
chr1_+_148747110	0.023	NM_004425 NM_022664	ECM1	extracellular matrix protein 1
chr16_-_29514140	0.022
chr2_-_199922047	0.022		SATB2	SATB homeobox 2
chr8_-_93181091	0.021	NM_001198628	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_13745234	0.021	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr4_+_71261066	0.020	NM_012390	SMR3B SMR3A	submaxillary gland androgen regulated protein 3B submaxillary gland androgen regulated protein 3A
chr2_+_38746742	0.020		GALM	galactose mutarotase (aldose 1-epimerase)
chr7_+_80105907	0.019		CD36	CD36 molecule (thrombospondin receptor)
chrX_-_48156287	0.018	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chr3_+_115495522	0.016	NM_173799	TIGIT	T cell immunoreceptor with Ig and ITIM domains
chr7_+_72913424	0.013	NM_182504	WBSCR28	Williams-Beuren syndrome chromosome region 28
chr2_-_200033445	0.012		SATB2	SATB homeobox 2
chrX_+_36163971	0.012	NM_001098843	CXorf30	chromosome X open reading frame 30
chr19_-_59019240	0.012	NM_144687	NLRP12	NLR family, pyrin domain containing 12
chr11_-_4827013	0.011	NM_001004758	OR51S1	olfactory receptor, family 51, subfamily S, member 1
chr17_-_33552166	0.010	NM_001123391 NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3F
chr13_+_23742846	0.010		SPATA13	spermatogenesis associated 13
chr6_-_50097606	0.010	NM_001037497 NM_001037728	DEFB110	defensin, beta 110 locus
chr17_+_55854636	0.010	NM_181707	C17orf64	chromosome 17 open reading frame 64
chr3_-_121117647	0.008		GSK3B	glycogen synthase kinase 3 beta
chr9_+_122923864	0.008		CEP110	centrosomal protein 110kDa
chr8_-_59575249	0.006	NM_000780	CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1
chr12_-_69317441	0.005	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr11_+_55617328	0.004	NM_001003750	OR8I2	olfactory receptor, family 8, subfamily I, member 2
chr7_+_80105718	0.003	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr4_-_170314382	0.003		SH3RF1	SH3 domain containing ring finger 1
chr16_-_18845223	0.003	NM_015092	SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr17_-_33602374	0.002	NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3F
chr2_-_138762909	0.001

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.65	8.54e-04	GO:0046578	regulation of Ras protein signal transduction
13.10	3.72e-03	GO:0032313	regulation of Rab GTPase activity
13.10	3.72e-03	GO:0032483	regulation of Rab protein signal transduction
6.94	1.24e-02	GO:0032318	regulation of Ras GTPase activity
5.99	3.56e-02	GO:0043087	regulation of GTPase activity
5.95	3.74e-02	GO:0033124	regulation of GTP catabolic process
3.82	4.36e-02	GO:0051056	regulation of small GTPase mediated signal transduction

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
12.85	9.38e-04	GO:0005097	Rab GTPase activator activity