Motif ID: SOX2.p2

Z-value: 1.168


Transcription factors associated with SOX2.p2:

Gene SymbolEntrez IDGene Name
SOX2 6657 SRY (sex determining region Y)-box 2



Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_39484073 1.714 NM_182935
 MOBP
myelin-associated oligodendrocyte basic protein
chr11_-_16380967 1.703 NM_001145819
NM_017508
 SOX6

SRY (sex determining region Y)-box 6

chr1_-_51660328 1.633 NM_001159969
 EPS15
epidermal growth factor receptor pathway substrate 15
chr2_+_169631777 1.526 NM_199204
 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_-_7923464 1.331 NM_001561
 TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr7_+_128802719 1.327 NM_001130722
 AHCYL2
adenosylhomocysteinase-like 2
chr1_+_181028016 1.195 NM_030769
 NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr8_-_38324809 1.160 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr7_+_106292932 1.157 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr22_-_25344037 1.155 CRYBB1
crystallin, beta B1
chr3_-_3127057 1.143 NM_000564
NM_175724
NM_175725
NM_175726
NM_175727
NM_175728
 IL5RA





interleukin 5 receptor, alpha





chr15_-_48198697 1.095 NM_024837
 ATP8B4
ATPase, class I, type 8B, member 4
chr1_-_41398126 1.066 NM_001172222
 SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr7_+_106292975 1.057 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr4_+_71806538 1.027 NM_001037442
NM_014961
 RUFY3

RUN and FYVE domain containing 3

chr21_+_34112456 1.017 ITSN1
intersectin 1 (SH3 domain protein)
chr7_-_112515068 1.006 NM_001146265
NM_018970
 GPR85

G protein-coupled receptor 85

chr10_-_61570665 0.992 NM_001149
 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr22_-_25343959 0.990 NM_001887
 CRYBB1
crystallin, beta B1
chr7_-_112515035 0.989 GPR85
G protein-coupled receptor 85

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.20 7.91e-03 GO:0010638 positive regulation of organelle organization
1.69 1.31e-02 GO:0033043 regulation of organelle organization
1.16 8.12e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
3.43 2.77e-03 GO:0000932 cytoplasmic mRNA processing body
3.07 1.11e-04 GO:0035770 RNA granule
1.31 4.95e-04 GO:0005856 cytoskeleton
1.22 6.67e-04 GO:0043228 non-membrane-bounded organelle
1.22 6.67e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.14 2.19e-04 GO:0005634 nucleus
1.03 1.13e-02 GO:0044464 cell part
1.03 1.17e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.33 1.58e-02 GO:0031625 ubiquitin protein ligase binding
1.59 9.63e-03 GO:0003712 transcription cofactor activity
1.58 1.07e-02 GO:0000988 protein binding transcription factor activity
1.58 1.07e-02 GO:0000989 transcription factor binding transcription factor activity
1.43 3.93e-03 GO:0019899 enzyme binding
1.17 2.43e-02 GO:0003676 nucleic acid binding
1.09 4.11e-02 GO:0005515 protein binding