Motif ID: SPI1.p2

Z-value: 3.873


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1



Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_35586950 5.684 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chrX_-_47374187 4.842 NM_001145252
CFP
complement factor properdin
chr1_+_159899528 4.539 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr12_+_48443232 4.203 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr16_-_87570716 3.690 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chrX_-_47374647 3.319 NM_002621
CFP
complement factor properdin
chr1_+_159817752 3.119 NM_201563
FCGR2C
Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr10_+_49562866 3.005 WDFY4
WDFY family member 4
chr6_+_31690957 2.999 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr11_+_65164767 2.956 SIPA1
signal-induced proliferation-associated 1
chr6_+_31661934 2.927 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr6_+_31662454 2.809 NM_205837
LST1
leukocyte specific transcript 1
chr2_+_108604111 2.778 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_10311262 2.636 NM_002162
ICAM3
intercellular adhesion molecule 3
chr17_+_53625084 2.591 NM_000502
EPX
eosinophil peroxidase
chr11_+_63864263 2.547 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr14_+_20319049 2.536 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr19_-_46504831 2.520


chr7_+_106292932 2.495 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr16_+_28413421 2.424 NM_018690
APOBR
apolipoprotein B receptor
chr16_-_29664765 2.363 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr12_+_50592379 2.337 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr7_+_106292975 2.316 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr9_-_129707392 2.258 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr16_+_56134077 2.241 NM_153837
GPR114
G protein-coupled receptor 114
chr17_-_40843530 2.197 ARHGAP27
Rho GTPase activating protein 27
chr16_+_56134037 2.180 GPR114
G protein-coupled receptor 114
chr19_-_55104875 2.147 NUP62
nucleoporin 62kDa
chr19_-_7672978 2.138 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr17_+_31455332 2.092 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr3_-_180467483 1.987 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr6_+_31648071 1.919 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr12_+_55018925 1.891 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr19_-_43608641 1.885 NM_001146202
NM_001146203
NM_001146204
NM_001146205
NM_001146206
NM_001146207
NM_170604
RASGRP4






RAS guanyl releasing protein 4






chr12_+_53241365 1.834 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr9_+_263025 1.828 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr19_-_13074973 1.788 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr19_+_59866217 1.773 LILRB4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
chr22_-_16080265 1.747 CECR1
cat eye syndrome chromosome region, candidate 1
chr17_-_43288137 1.742 NM_199262
SP6
Sp6 transcription factor
chr1_-_21375939 1.712 NM_001198801
NM_001198802
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr1_-_156078115 1.660 NM_005894
CD5L
CD5 molecule-like
chr6_+_31647854 1.643 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr7_+_101715110 1.643 NM_020979
SH2B2
SH2B adaptor protein 2
chr19_+_14412080 1.641 NM_213560
PKN1
protein kinase N1
chr19_+_14412052 1.638 PKN1
protein kinase N1
chr8_+_145158432 1.635 NM_001134374
NM_198572
SPATC1

spermatogenesis and centriole associated 1

chr22_+_35639564 1.625 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr12_-_12310969 1.604 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr19_+_40895669 1.600 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr1_+_26517032 1.568 CD52
CD52 molecule
chr1_+_154351200 1.549 LMNA
lamin A/C
chr12_-_56422120 1.505 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr5_+_148711419 1.478 GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr22_-_35970230 1.475 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_+_21956335 1.463 NM_003867
FGF17
fibroblast growth factor 17
chr17_+_31562577 1.459 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr3_+_108724472 1.454 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr19_+_14412087 1.437 PKN1
protein kinase N1
chr12_-_50004102 1.432 BIN2
bridging integrator 2
chr7_+_101715137 1.432 SH2B2
SH2B adaptor protein 2
chr12_+_48443588 1.425 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr15_-_76313896 1.419 NM_015162
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr11_-_18226743 1.398 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr1_+_36462625 1.397 THRAP3
thyroid hormone receptor associated protein 3
chr11_+_47386707 1.395 SLC39A13
solute carrier family 39 (zinc transporter), member 13
chr20_-_44612619 1.394 NM_080721
C20orf123
chromosome 20 open reading frame 123
chrX_+_41191630 1.367 NM_022567
NYX
nyctalopin
chr11_+_47386621 1.354 NM_001128225
NM_152264
SLC39A13

solute carrier family 39 (zinc transporter), member 13

chr1_+_26517045 1.353 CD52
CD52 molecule
chr19_+_60109319 1.352 NM_001145457
NM_001145458
NM_004829
NCR1


natural cytotoxicity triggering receptor 1


chr12_-_50004208 1.352 BIN2
bridging integrator 2
chr16_-_87297525 1.349 NM_001171816
RNF166
ring finger protein 166
chr1_-_205186330 1.334 NM_002644
PIGR
polymeric immunoglobulin receptor
chr3_-_113334657 1.332 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr4_+_71986927 1.330 NM_173468
MOBKL1A
MOB1, Mps One Binder kinase activator-like 1A (yeast)
chr12_-_50004172 1.322 NM_016293
BIN2
bridging integrator 2
chr12_-_56159631 1.319 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr12_-_53071285 1.319 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr6_-_32299757 1.313 NM_004557
NOTCH4
notch 4
chr9_-_99740243 1.306 NM_197978
HEMGN
hemogen
chr19_-_60611136 1.289 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr22_-_35970133 1.284 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr9_-_73573121 1.275 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr19_+_59776293 1.267 LILRA2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
chr19_-_13074669 1.266 LYL1
lymphoblastic leukemia derived sequence 1
chr12_-_53664722 1.258 NM_001136030
KIAA0748
KIAA0748
chr1_+_207995999 1.251 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr6_+_31691745 1.236 NM_032955
AIF1
allograft inflammatory factor 1
chr17_+_31664143 1.235 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr11_+_72658586 1.230 NM_176798
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr4_+_91035025 1.211 NM_007351
MMRN1
multimerin 1
chr5_-_176869943 1.207 NM_001144875
NM_001144876
DOK3

docking protein 3

chr5_-_176258920 1.207 NM_002115
HK3
hexokinase 3 (white cell)
chr12_-_56159895 1.200 NM_032496
ARHGAP9
Rho GTPase activating protein 9
chr1_-_145712107 1.197 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr7_+_149895390 1.195 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr22_+_42900168 1.194 NM_001137605
PARVG
parvin, gamma
chrX_-_44945025 1.193 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr2_+_66519949 1.188 MEIS1
Meis homeobox 1
chr17_-_31441390 1.183 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr12_-_53065758 1.182 ZNF385A
zinc finger protein 385A
chr6_+_31651319 1.180 NM_000594
TNF
tumor necrosis factor
chr6_-_88911708 1.176 NM_033181
CNR1
cannabinoid receptor 1 (brain)
chr19_-_6432765 1.169 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr19_-_17349096 1.167 NM_031310
PLVAP
plasmalemma vesicle associated protein
chr2_+_169637255 1.164 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr7_-_100077072 1.158 NM_003227
TFR2
transferrin receptor 2
chr7_+_73826244 1.157 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr6_-_154719560 1.156 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr7_+_128367961 1.153 NM_001098627
IRF5
interferon regulatory factor 5
chr8_+_126511739 1.146 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr1_-_26517342 1.141 NM_145345
UBXN11
UBX domain protein 11
chrX_-_135577102 1.135 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr5_-_169657395 1.135 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_156526182 1.133 NM_001765
CD1C
CD1c molecule
chr11_-_64403712 1.132 EHD1
EH-domain containing 1
chrX_+_48427137 1.128 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr11_+_65164167 1.127 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr12_-_53661888 1.124 NM_001098815
KIAA0748
KIAA0748
chr11_+_2877486 1.120 NM_183233
SLC22A18
solute carrier family 22, member 18
chr7_-_132371208 1.115 EEF1G
eukaryotic translation elongation factor 1 gamma
chr6_-_31658044 1.109 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chrX_+_48427103 1.105 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr18_-_50004770 1.102 MBD2
methyl-CpG binding domain protein 2
chr15_+_36332258 1.100 NM_152594
SPRED1
sprouty-related, EVH1 domain containing 1
chr17_+_44642587 1.097 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr19_-_8548232 1.093 MYO1F
myosin IF
chr7_+_18296569 1.092 HDAC9
histone deacetylase 9
chrX_-_134883798 1.091 NM_173470
MMGT1
membrane magnesium transporter 1
chr8_-_116749382 1.091 TRPS1
trichorhinophalangeal syndrome I
chr11_+_66927955 1.087 TBC1D10C
TBC1 domain family, member 10C
chr16_+_48865521 1.087 ADCY7
adenylate cyclase 7
chr17_-_55824083 1.086 USP32
ubiquitin specific peptidase 32
chr10_+_17312654 1.079 VIM
vimentin
chr5_+_140871107 1.071


chr17_-_59363352 1.055 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr19_+_40465249 1.050 NM_021175
HAMP
hepcidin antimicrobial peptide
chr22_+_23333610 1.050 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr3_-_15349086 1.043 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr7_-_3049872 1.043 NM_032415
CARD11
caspase recruitment domain family, member 11
chr1_-_180908639 1.036 NM_001102450
NM_033345
RGS8

regulator of G-protein signaling 8

chr7_+_149779011 1.033 GIMAP8
GTPase, IMAP family member 8
chr1_+_154351162 1.028 LMNA
lamin A/C
chr16_+_31274020 1.027 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr5_-_169657312 1.020 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_169657360 1.018 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_+_46323575 1.012 DGKZ
diacylglycerol kinase, zeta
chr11_+_59902530 1.010 NM_021201
NM_206938
NM_206939
NM_206940
MS4A7



membrane-spanning 4-domains, subfamily A, member 7



chr7_+_106293112 1.010 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_-_122862447 1.009 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr22_+_23153529 1.007 NM_000675
ADORA2A
adenosine A2a receptor
chr19_+_54068373 0.997 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr11_+_118269310 0.996 NM_032966
CXCR5
chemokine (C-X-C motif) receptor 5
chr11_+_46323495 0.993 DGKZ
diacylglycerol kinase, zeta
chr6_+_144649142 0.991 UTRN
utrophin
chr20_-_1548589 0.987 NM_001083910
NM_001135844
NM_006065
SIRPB1


signal-regulatory protein beta 1


chr19_-_15436333 0.986 NM_022904
RASAL3
RAS protein activator like 3
chr12_-_8656705 0.982 NM_020661
AICDA
activation-induced cytidine deaminase
chr11_-_117640078 0.977


chr5_-_169657192 0.977 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr2_-_231498184 0.972 NM_005683
GPR55
G protein-coupled receptor 55
chr10_-_49483002 0.971 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr6_+_108988797 0.970 FOXO3
forkhead box O3
chr3_-_120861959 0.968 NM_022135
POPDC2
popeye domain containing 2
chr1_+_78126787 0.968 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr12_+_52103905 0.966 NM_001164690
NM_001164691
NM_020547
AMHR2


anti-Mullerian hormone receptor, type II


chr16_+_80086454 0.965 NM_030629
CMIP
c-Maf-inducing protein
chr1_+_36462583 0.964 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr3_-_122862391 0.960 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_51474558 0.958 RNF11
ring finger protein 11
chr19_-_56726704 0.952 NM_001177547
NM_001177548
NM_001177549
NM_001245
NM_198845
NM_198846
SIGLEC6





sialic acid binding Ig-like lectin 6





chr5_-_176869440 0.949 DOK3
docking protein 3
chr2_-_168812132 0.947 NM_013233
STK39
serine threonine kinase 39
chr19_+_59865935 0.944 NM_001081438
NM_006847
LILRB4

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4

chr5_+_159589014 0.940 NM_001445
FABP6
fatty acid binding protein 6, ileal
chr17_+_35532994 0.939 MSL1
male-specific lethal 1 homolog (Drosophila)
chr10_-_71002998 0.932 NM_020999
NEUROG3
neurogenin 3
chr7_+_150065376 0.927 NM_018384
GIMAP5
GTPase, IMAP family member 5
chr22_+_42908612 0.919 PARVG
parvin, gamma
chr6_+_37081387 0.917 NM_173558
FGD2
FYVE, RhoGEF and PH domain containing 2
chr1_-_27113018 0.915 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr16_+_31273969 0.912 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr7_-_81237162 0.910 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr1_+_111544469 0.908


chr11_-_76059435 0.908 NM_001128922
LRRC32
leucine rich repeat containing 32
chr5_-_157218555 0.908 NM_001195555
NM_001195556
NM_014666
CLINT1


clathrin interactor 1


chr1_-_158815895 0.907 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr1_+_156590109 0.901 NM_001042583
NM_001042584
NM_001042585
NM_001042586
NM_001042587
NM_001185107
NM_001185108
NM_001185110
NM_001185112
NM_001185113
NM_001185114
NM_001185115
NM_030893
CD1E












CD1e molecule












chr1_+_43539239 0.898 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr2_+_241213334 0.896 NM_005301
GPR35
G protein-coupled receptor 35
chr11_+_1818007 0.890 NM_001145841
TNNI2
troponin I type 2 (skeletal, fast)
chr3_-_187025501 0.889 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr1_-_205161821 0.889 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr10_+_99884370 0.888 NM_014472
C10orf28
chromosome 10 open reading frame 28
chr3_+_3056307 0.884 NM_175612
CNTN4
contactin 4
chr16_-_30301634 0.883 NM_052838
SEPT1
septin 1
chr17_-_35975227 0.882 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr1_+_157441824 0.879 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr1_+_51474502 0.876 RNF11
ring finger protein 11

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 6.15e-17 GO:0050794 regulation of cellular process
1.12 1.29e-15 GO:0065007 biological regulation
1.12 4.92e-15 GO:0050789 regulation of biological process
1.28 7.52e-13 GO:0048583 regulation of response to stimulus
1.21 7.83e-11 GO:0048518 positive regulation of biological process
1.32 4.04e-10 GO:0002376 immune system process
1.30 4.93e-10 GO:0009966 regulation of signal transduction
1.23 1.13e-09 GO:0048523 negative regulation of cellular process
1.22 2.46e-09 GO:0048519 negative regulation of biological process
1.15 2.56e-09 GO:0044260 cellular macromolecule metabolic process
1.21 2.69e-09 GO:0048522 positive regulation of cellular process
1.06 3.91e-09 GO:0009987 cellular process
1.16 3.86e-08 GO:0031323 regulation of cellular metabolic process
1.25 6.01e-08 GO:0023051 regulation of signaling
1.15 6.85e-08 GO:0019222 regulation of metabolic process
1.46 2.10e-07 GO:0001775 cell activation
1.64 4.66e-07 GO:0045321 leukocyte activation
1.14 6.78e-07 GO:0051716 cellular response to stimulus
1.22 7.12e-07 GO:0006464 protein modification process
1.16 7.36e-07 GO:0016043 cellular component organization
1.12 8.20e-07 GO:0043170 macromolecule metabolic process
1.15 1.05e-06 GO:0080090 regulation of primary metabolic process
1.15 2.62e-06 GO:0007165 signal transduction
1.15 3.60e-06 GO:0071840 cellular component organization or biogenesis
1.29 4.74e-06 GO:0043067 regulation of programmed cell death
1.15 1.09e-05 GO:0060255 regulation of macromolecule metabolic process
1.28 1.15e-05 GO:0042981 regulation of apoptosis
1.28 1.32e-05 GO:0010941 regulation of cell death
1.13 1.96e-05 GO:0023052 signaling
1.26 2.23e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.32 2.28e-05 GO:0046907 intracellular transport
1.17 3.23e-05 GO:0044267 cellular protein metabolic process
1.19 7.09e-05 GO:0043412 macromolecule modification
1.24 8.74e-05 GO:0009893 positive regulation of metabolic process
1.24 1.06e-04 GO:0031325 positive regulation of cellular metabolic process
1.21 1.16e-04 GO:0006996 organelle organization
1.44 1.17e-04 GO:0051056 regulation of small GTPase mediated signal transduction
1.15 1.48e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.40 2.16e-04 GO:0002684 positive regulation of immune system process
1.60 2.25e-04 GO:0046649 lymphocyte activation
1.31 2.45e-04 GO:0002682 regulation of immune system process
1.15 2.52e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52 4.53e-04 GO:0030097 hemopoiesis
1.80 1.03e-03 GO:0030098 lymphocyte differentiation
2.14 1.10e-03 GO:0002263 cell activation involved in immune response
2.14 1.10e-03 GO:0002366 leukocyte activation involved in immune response
1.63 1.26e-03 GO:0050900 leukocyte migration
1.27 1.33e-03 GO:0009891 positive regulation of biosynthetic process
1.14 1.33e-03 GO:0071842 cellular component organization at cellular level
1.46 1.36e-03 GO:0002520 immune system development
1.24 1.47e-03 GO:0006793 phosphorus metabolic process
1.24 1.47e-03 GO:0006796 phosphate metabolic process
1.15 1.58e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.37 1.81e-03 GO:0050776 regulation of immune response
1.28 1.87e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.33 2.19e-03 GO:0006928 cellular component movement
1.31 2.45e-03 GO:0051726 regulation of cell cycle
1.23 2.47e-03 GO:0051649 establishment of localization in cell
1.28 2.62e-03 GO:0006955 immune response
1.46 2.90e-03 GO:0048534 hemopoietic or lymphoid organ development
1.19 3.09e-03 GO:0065009 regulation of molecular function
1.26 3.18e-03 GO:0040011 locomotion
1.88 3.58e-03 GO:0007173 epidermal growth factor receptor signaling pathway
1.18 3.83e-03 GO:0016070 RNA metabolic process
1.66 4.12e-03 GO:0032318 regulation of Ras GTPase activity
1.26 4.82e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.33 4.91e-03 GO:0007599 hemostasis
1.20 5.39e-03 GO:0035556 intracellular signal transduction
1.24 5.52e-03 GO:0042127 regulation of cell proliferation
1.14 5.61e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.13 6.01e-03 GO:0009889 regulation of biosynthetic process
1.20 6.75e-03 GO:0051641 cellular localization
1.33 7.51e-03 GO:0007596 blood coagulation
1.33 7.51e-03 GO:0050817 coagulation
1.13 7.73e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.26 7.89e-03 GO:0048584 positive regulation of response to stimulus
1.14 8.38e-03 GO:0006950 response to stress
1.08 8.50e-03 GO:0044237 cellular metabolic process
1.13 9.12e-03 GO:0031326 regulation of cellular biosynthetic process
1.08 1.01e-02 GO:0044238 primary metabolic process
1.30 1.03e-02 GO:0042060 wound healing
1.46 1.08e-02 GO:0002694 regulation of leukocyte activation
1.58 1.26e-02 GO:0043087 regulation of GTPase activity
1.13 1.36e-02 GO:0010468 regulation of gene expression
1.34 1.48e-02 GO:0043069 negative regulation of programmed cell death
1.35 1.49e-02 GO:0007243 intracellular protein kinase cascade
1.35 1.49e-02 GO:0023014 signal transduction via phosphorylation event
1.45 1.50e-02 GO:0050865 regulation of cell activation
1.39 1.53e-02 GO:0051098 regulation of binding
1.45 1.55e-02 GO:0046578 regulation of Ras protein signal transduction
1.57 1.74e-02 GO:0033124 regulation of GTP catabolic process
1.43 1.96e-02 GO:0051101 regulation of DNA binding
1.34 2.31e-02 GO:0016477 cell migration
2.24 2.39e-02 GO:0002285 lymphocyte activation involved in immune response
2.10 2.44e-02 GO:0045727 positive regulation of translation
1.93 2.94e-02 GO:0060326 cell chemotaxis
1.23 3.01e-02 GO:0009611 response to wounding
1.33 3.07e-02 GO:0043066 negative regulation of apoptosis
1.30 3.38e-02 GO:0043068 positive regulation of programmed cell death
1.46 3.42e-02 GO:0051249 regulation of lymphocyte activation
1.12 3.66e-02 GO:0019538 protein metabolic process
1.23 3.82e-02 GO:0051128 regulation of cellular component organization
1.25 4.54e-02 GO:0006468 protein phosphorylation
1.21 4.55e-02 GO:0009605 response to external stimulus
1.31 4.65e-02 GO:0048870 cell motility
1.31 4.65e-02 GO:0051674 localization of cell
1.21 4.79e-02 GO:0032268 regulation of cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 5.54e-16 GO:0005622 intracellular
1.07 1.52e-14 GO:0044424 intracellular part
1.13 1.13e-11 GO:0005634 nucleus
1.08 4.53e-11 GO:0043226 organelle
1.08 5.67e-11 GO:0043229 intracellular organelle
1.09 6.79e-11 GO:0043227 membrane-bounded organelle
1.09 1.14e-10 GO:0043231 intracellular membrane-bounded organelle
1.03 1.63e-09 GO:0005623 cell
1.03 2.09e-09 GO:0044464 cell part
1.08 8.87e-09 GO:0005737 cytoplasm
1.20 1.86e-07 GO:0005829 cytosol
1.19 4.15e-07 GO:0044428 nuclear part
1.24 4.09e-06 GO:0005654 nucleoplasm
1.10 6.41e-06 GO:0044422 organelle part
1.19 7.79e-06 GO:0031981 nuclear lumen
1.10 8.28e-06 GO:0044446 intracellular organelle part
1.09 7.27e-05 GO:0044444 cytoplasmic part
1.29 1.01e-04 GO:0044451 nucleoplasm part
1.13 3.05e-04 GO:0043234 protein complex
1.14 1.31e-03 GO:0043233 organelle lumen
1.11 2.49e-03 GO:0032991 macromolecular complex
1.14 2.57e-03 GO:0031974 membrane-enclosed lumen
1.14 4.88e-03 GO:0070013 intracellular organelle lumen
1.34 1.35e-02 GO:0048471 perinuclear region of cytoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 3.47e-33 GO:0005515 protein binding
1.06 1.29e-11 GO:0005488 binding
1.44 3.81e-07 GO:0060589 nucleoside-triphosphatase regulator activity
1.59 6.28e-07 GO:0005096 GTPase activator activity
1.43 8.74e-07 GO:0030695 GTPase regulator activity
1.42 3.09e-05 GO:0008047 enzyme activator activity
1.25 1.06e-04 GO:0030528 transcription regulator activity
1.36 7.39e-04 GO:0019904 protein domain specific binding
1.75 1.14e-03 GO:0005099 Ras GTPase activator activity
1.27 1.18e-03 GO:0019899 enzyme binding
1.23 1.32e-03 GO:0030234 enzyme regulator activity
1.41 1.53e-03 GO:0016564 transcription repressor activity
1.41 3.16e-03 GO:0005083 small GTPase regulator activity
1.76 3.87e-03 GO:0035257 nuclear hormone receptor binding
1.35 7.74e-03 GO:0003712 transcription cofactor activity
1.34 9.32e-03 GO:0000988 protein binding transcription factor activity
1.34 9.32e-03 GO:0000989 transcription factor binding transcription factor activity
1.67 1.19e-02 GO:0051427 hormone receptor binding
1.43 2.10e-02 GO:0003713 transcription coactivator activity
1.39 2.78e-02 GO:0032403 protein complex binding
1.40 3.33e-02 GO:0019900 kinase binding
1.49 3.82e-02 GO:0004721 phosphoprotein phosphatase activity