Motif ID: SPIB.p2

Z-value: 4.680


Transcription factors associated with SPIB.p2:

Gene SymbolEntrez IDGene Name
SPIB 6689 Spi-B transcription factor (Spi-1/PU.1 related)



Activity profile for motif SPIB.p2.

activity profile for motif SPIB.p2


Sorted Z-values histogram for motif SPIB.p2

Sorted Z-values for motif SPIB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_48443232 8.544 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr5_-_71838875 7.066 NM_152625
ZNF366
zinc finger protein 366
chr6_+_31661934 6.964 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr6_+_31662454 6.786 NM_205837
LST1
leukocyte specific transcript 1
chr17_+_31455332 6.561 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr17_-_40843530 6.336 ARHGAP27
Rho GTPase activating protein 27
chr4_+_91035025 6.085 NM_007351
MMRN1
multimerin 1
chr5_+_61910318 5.765 NM_181506
LRRC70
leucine rich repeat containing 70
chr12_+_48443588 5.662 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr17_+_31664143 5.060 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr17_+_44643067 4.615 ABI3
ABI family, member 3
chr17_-_18890963 4.576 NM_006613
GRAP
GRB2-related adaptor protein
chr1_-_111848265 4.504 NM_000677
NM_020683
ADORA3

adenosine A3 receptor

chr2_-_175207521 4.425 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr7_+_149778815 4.395 GIMAP8
GTPase, IMAP family member 8
chr1_+_111818111 4.036 NM_174896
C1orf162
chromosome 1 open reading frame 162
chr2_+_102401580 3.969 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr7_+_149778869 3.961 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr6_-_11490487 3.841 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chrX_-_44945025 3.777 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr12_+_50592379 3.709 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr7_+_139175420 3.692 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr14_+_99601498 3.688 NM_016337
EVL
Enah/Vasp-like
chr17_+_73638430 3.673 NM_152468
TMC8
transmembrane channel-like 8
chr16_+_28413421 3.637 NM_018690
APOBR
apolipoprotein B receptor
chr6_+_31690957 3.634 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr14_+_99601517 3.632 EVL
Enah/Vasp-like
chr11_-_60880799 3.499 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr17_+_31562577 3.453 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr16_-_3567354 3.405 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr1_+_207995999 3.397 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr19_-_40925151 3.274 NM_024660
TMEM149
transmembrane protein 149
chr7_+_106293112 3.266 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_149779011 3.253 GIMAP8
GTPase, IMAP family member 8
chr11_+_63864263 3.216 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr19_-_17236522 3.182 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr11_+_120966280 3.009 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr17_+_37693090 2.990 NM_003152
STAT5A
signal transducer and activator of transcription 5A
chr5_-_169657395 2.974 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr6_-_154719560 2.955 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr7_+_106292932 2.887 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_+_157441133 2.882 NM_002036
DARC
Duffy blood group, chemokine receptor
chr14_+_23852152 2.881 NM_181657
LTB4R
leukotriene B4 receptor
chr1_-_59020875 2.873 JUN
jun proto-oncogene
chr7_+_149895390 2.836 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr2_-_68952006 2.822 NM_014482
BMP10
bone morphogenetic protein 10
chr18_-_65766068 2.812 CD226
CD226 molecule
chr17_-_44642934 2.774 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr7_+_106292975 2.766 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr19_+_46774370 2.715 NM_001098506
NM_033543
CEACAM21

carcinoembryonic antigen-related cell adhesion molecule 21

chr3_-_113701073 2.687 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr2_+_233633348 2.685 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr7_+_128367961 2.663 NM_001098627
IRF5
interferon regulatory factor 5
chr19_-_56567602 2.645 NM_005601
NKG7
natural killer cell group 7 sequence
chr1_+_246635918 2.644 NM_030904
OR2T1
olfactory receptor, family 2, subfamily T, member 1
chr5_-_169657192 2.599 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr22_+_21359175 2.596 IGLV3-25
immunoglobulin lambda variable 3-25
chr5_-_169657312 2.595 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr19_+_3129735 2.593 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr7_-_38341697 2.574 TRGV7
T cell receptor gamma variable 7 pseudogene
chr2_+_233633279 2.558 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr9_+_107464558 2.524 NM_005421
TAL2
T-cell acute lymphocytic leukemia 2
chr11_-_58736897 2.522 NM_001039396
MPEG1
macrophage expressed 1
chr12_-_15005761 2.500 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr5_-_169657360 2.490 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr19_-_53935648 2.410 NM_017805
RASIP1
Ras interacting protein 1
chr15_-_53440069 2.381 CCPG1
cell cycle progression 1
chr12_-_56159631 2.355 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chrX_-_47374187 2.354 NM_001145252
CFP
complement factor properdin
chr9_+_263025 2.343 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr12_+_102505180 2.336 NM_017564
STAB2
stabilin 2
chr14_+_87541220 2.332 NM_003608
GPR65
G protein-coupled receptor 65
chrX_+_48427137 2.330 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr6_+_130381408 2.314 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr13_+_110653407 2.313 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr3_+_120799411 2.308 NM_015900
PLA1A
phospholipase A1 member A
chr21_-_38792173 2.295 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr11_+_65164167 2.294 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr5_-_176869463 2.272 NM_024872
DOK3
docking protein 3
chr2_-_183095308 2.267 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr3_-_122862447 2.253 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr16_-_88358946 2.237 FANCA
Fanconi anemia, complementation group A
chr3_-_122862391 2.232 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr4_-_10295412 2.207 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr1_-_156078115 2.201 NM_005894
CD5L
CD5 molecule-like
chr3_+_46423682 2.190 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr5_-_176869440 2.184 DOK3
docking protein 3
chr1_-_205210567 2.184 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr1_+_148511806 2.183 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr7_-_81237162 2.173 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr19_+_14412080 2.150 NM_213560
PKN1
protein kinase N1
chr2_+_173394560 2.131 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr2_-_225519974 2.126 DOCK10
dedicator of cytokinesis 10
chr19_+_14412052 2.121 PKN1
protein kinase N1
chr12_+_53241365 2.089 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr19_-_13074973 2.087 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr1_+_202000906 2.081 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr15_+_38849450 2.055 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr16_-_30301357 2.015 SEPT1
septin 1
chr19_-_40325194 2.008 LGI4
leucine-rich repeat LGI family, member 4
chr7_-_5429702 1.996 NM_001080495
TNRC18
trinucleotide repeat containing 18
chrX_+_149364377 1.994 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chr12_-_120503241 1.994 NM_032590
KDM2B
lysine (K)-specific demethylase 2B
chr19_+_14554895 1.970 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr17_+_44642587 1.969 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr14_+_104462210 1.966 NM_138790
PLD4
phospholipase D family, member 4
chr11_+_59979857 1.955 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr6_-_159386007 1.953 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr5_-_95774444 1.948 NM_001177876
PCSK1
proprotein convertase subtilisin/kexin type 1
chrX_+_48427103 1.939 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr19_-_6432765 1.938 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr5_-_134815886 1.925 NM_001099221
TIFAB
TRAF-interacting protein with forkhead-associated domain, family member B
chrX_-_100527799 1.921 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr1_-_205161821 1.912 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr3_-_184756101 1.900 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr19_+_14412087 1.891 PKN1
protein kinase N1
chr4_+_39874921 1.886 NM_004310
RHOH
ras homolog gene family, member H
chr1_+_210805319 1.877 NM_001030287
ATF3
activating transcription factor 3
chr6_+_167456230 1.869 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr22_+_21495273 1.846


chr14_+_104462199 1.844 PLD4
phospholipase D family, member 4
chr14_+_104462195 1.843 PLD4
phospholipase D family, member 4
chr16_-_66590856 1.837 NM_022355
DPEP2
dipeptidase 2
chr4_-_123596921 1.803 NM_000586
IL2
interleukin 2
chr6_-_88911708 1.799 NM_033181
CNR1
cannabinoid receptor 1 (brain)
chr5_-_176869148 1.796


chr17_-_70220605 1.787 NM_139018
CD300LF
CD300 molecule-like family member f
chr2_-_31293882 1.787 NM_001145122
CAPN14
calpain 14
chr1_-_36562341 1.786 NM_018166
FAM176B
family with sequence similarity 176, member B
chrX_-_47374647 1.784 NM_002621
CFP
complement factor properdin
chr9_+_138677197 1.781 NM_201446
NM_016215
EGFL7

EGF-like-domain, multiple 7

chr6_+_31647854 1.777 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr4_+_68107039 1.752 NM_012108
STAP1
signal transducing adaptor family member 1
chr19_+_54530458 1.738 CD37
CD37 molecule
chr2_+_36436873 1.735 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr9_+_92629525 1.732 NM_001174167
SYK
spleen tyrosine kinase
chr3_-_58538530 1.732 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr12_-_8584658 1.728 NM_014358
CLEC4E
C-type lectin domain family 4, member E
chr21_-_46528594 1.715 MCM3AP
minichromosome maintenance complex component 3 associated protein
chr14_-_20340830 1.712 NM_002933
NM_198234
NM_198235
RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr19_-_59383944 1.706 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr4_-_164754106 1.690 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr20_+_19863716 1.689 RIN2
Ras and Rab interactor 2
chr17_+_18971506 1.680 NM_001129778
GRAPL
GRB2-related adaptor protein-like
chr3_+_39346200 1.679 NM_005201
CCR8
chemokine (C-C motif) receptor 8
chr7_-_37454933 1.677 NM_014800
ELMO1
engulfment and cell motility 1
chr6_+_158654890 1.674


chr5_+_52812236 1.659 NM_006350
NM_013409
FST

follistatin

chr3_-_46043982 1.650 NM_001024644
NM_005283
XCR1

chemokine (C motif) receptor 1

chr9_+_124835608 1.649 RABGAP1
GPR21
RAB GTPase activating protein 1
G protein-coupled receptor 21
chr19_+_17495109 1.639 NM_001098524
NM_173544
FAM129C

family with sequence similarity 129, member C

chr22_+_35639564 1.638 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr18_+_41659542 1.637 NM_213602
SIGLEC15
sialic acid binding Ig-like lectin 15
chr12_+_8499788 1.634 NM_001007033
CLEC6A
C-type lectin domain family 6, member A
chr1_+_50348052 1.628 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr13_-_32678142 1.623 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr3_+_66527586 1.621


chr17_+_2646481 1.619 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr16_-_30301634 1.609 NM_052838
SEPT1
septin 1
chr1_+_157441824 1.607 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr12_-_122155998 1.593 PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr11_+_59804634 1.593 NM_148975
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4
chr1_-_25164061 1.573 NM_001031680
RUNX3
runt-related transcription factor 3
chr19_+_54530485 1.568 NM_001040031
NM_001774
CD37

CD37 molecule

chr12_-_24628348 1.565 C12orf67
chromosome 12 open reading frame 67
chr2_+_96355661 1.560 NM_178495
NM_001163524
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr6_+_158654464 1.558 TULP4
tubby like protein 4
chr7_+_99793561 1.555 NM_178238
PILRB
paired immunoglobin-like type 2 receptor beta
chr6_-_32742265 1.549 NM_002123
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr6_-_11219932 1.532 NM_207582
ERVFRDE1
HERV-FRD provirus ancestral Env polyprotein
chr9_-_129580732 1.525 NM_170600
SH2D3C
SH2 domain containing 3C
chr7_-_4867963 1.519 NM_020144
PAPOLB
poly(A) polymerase beta (testis specific)
chr7_+_150013716 1.511 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr5_-_156468614 1.503 NM_032782
HAVCR2
hepatitis A virus cellular receptor 2
chr12_-_101398288 1.502 IGF1
insulin-like growth factor 1 (somatomedin C)
chr19_+_40824486 1.498 NM_014209
ETV2
ets variant 2
chr19_+_54530497 1.497 CD37
CD37 molecule
chr10_+_91488704 1.496 KIF20B
kinesin family member 20B
chr3_-_180467483 1.490 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr9_-_35608300 1.471 NM_001782
CD72
CD72 molecule
chr16_-_49272741 1.470 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr19_-_17349096 1.461 NM_031310
PLVAP
plasmalemma vesicle associated protein
chr1_-_167969802 1.456 NM_000450
SELE
selectin E
chr9_-_129707392 1.454 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr17_+_8154864 1.444 NM_025014
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr11_+_46323575 1.423 DGKZ
diacylglycerol kinase, zeta
chr19_+_54530512 1.418 CD37
CD37 molecule
chr22_+_29333069 1.415 NM_000355
NM_001184726
TCN2

transcobalamin II

chr22_+_35586950 1.410 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chrX_+_15428820 1.404 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr5_-_131907071 1.403 NM_000879
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr1_-_154727014 1.402 MEF2D
myocyte enhancer factor 2D
chr22_-_38619739 1.401 NM_152512
ENTHD1
ENTH domain containing 1
chr11_+_65164767 1.397 SIPA1
signal-induced proliferation-associated 1
chr10_+_115300579 1.397 NM_001177660
HABP2
hyaluronan binding protein 2
chr11_+_69922236 1.386 NM_001184740
NM_005231
NM_138565
CTTN


cortactin


chr9_+_122890394 1.374 NM_007018
CEP110
centrosomal protein 110kDa
chr17_-_64568641 1.373 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr3_+_32968069 1.365 NM_005508
CCR4
chemokine (C-C motif) receptor 4
chr10_+_82268433 1.362 TSPAN14
tetraspanin 14

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.45 2.50e-15 GO:0002376 immune system process
1.42 2.48e-07 GO:0006955 immune response
1.10 5.61e-06 GO:0050794 regulation of cellular process
1.82 1.19e-05 GO:0051251 positive regulation of lymphocyte activation
1.76 4.01e-05 GO:0002696 positive regulation of leukocyte activation
1.76 4.24e-05 GO:0050867 positive regulation of cell activation
1.13 7.75e-05 GO:0044260 cellular macromolecule metabolic process
1.86 9.39e-05 GO:0050870 positive regulation of T cell activation
1.37 1.07e-04 GO:0002682 regulation of immune system process
1.34 1.31e-04 GO:0006952 defense response
1.08 2.01e-04 GO:0065007 biological regulation
1.09 2.43e-04 GO:0050789 regulation of biological process
1.15 2.93e-04 GO:0007165 signal transduction
1.21 4.24e-04 GO:0010467 gene expression
1.44 7.74e-04 GO:0050776 regulation of immune response
1.20 8.01e-04 GO:0048583 regulation of response to stimulus
1.44 9.82e-04 GO:0002684 positive regulation of immune system process
1.30 1.05e-03 GO:0009611 response to wounding
1.13 1.20e-03 GO:0051716 cellular response to stimulus
1.61 1.89e-03 GO:0051249 regulation of lymphocyte activation
1.68 1.98e-03 GO:0050863 regulation of T cell activation
1.21 2.16e-03 GO:0016070 RNA metabolic process
1.17 2.97e-03 GO:0048519 negative regulation of biological process
1.13 4.28e-03 GO:0023052 signaling
1.39 4.82e-03 GO:0007599 hemostasis
1.39 5.01e-03 GO:0007596 blood coagulation
1.39 5.01e-03 GO:0050817 coagulation
1.70 5.07e-03 GO:0050900 leukocyte migration
1.36 7.59e-03 GO:0006928 cellular component movement
1.55 7.65e-03 GO:0002694 regulation of leukocyte activation
1.17 9.19e-03 GO:0048523 negative regulation of cellular process
1.36 1.12e-02 GO:0016071 mRNA metabolic process
1.05 1.24e-02 GO:0009987 cellular process
1.37 1.24e-02 GO:0001775 cell activation
1.17 1.32e-02 GO:0090304 nucleic acid metabolic process
1.52 1.42e-02 GO:0050865 regulation of cell activation
1.13 1.49e-02 GO:0060255 regulation of macromolecule metabolic process
1.26 2.41e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.26 2.47e-02 GO:0031324 negative regulation of cellular metabolic process
1.12 2.93e-02 GO:0031323 regulation of cellular metabolic process
1.08 3.02e-02 GO:0050896 response to stimulus
1.40 3.06e-02 GO:0006397 mRNA processing
1.30 3.48e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.46 3.91e-02 GO:0006954 inflammatory response
1.24 4.09e-02 GO:0009892 negative regulation of metabolic process
1.50 4.32e-02 GO:0045321 leukocyte activation
1.58 4.43e-02 GO:0002764 immune response-regulating signaling pathway
1.30 4.75e-02 GO:0006396 RNA processing

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.05 4.77e-06 GO:0005622 intracellular
1.05 1.94e-05 GO:0044424 intracellular part
1.03 3.44e-04 GO:0005623 cell
1.03 4.21e-04 GO:0044464 cell part
1.07 4.33e-04 GO:0043227 membrane-bounded organelle
1.06 6.87e-04 GO:0043231 intracellular membrane-bounded organelle
1.06 1.16e-03 GO:0043226 organelle
1.06 1.34e-03 GO:0043229 intracellular organelle
1.09 1.61e-03 GO:0005634 nucleus
1.14 1.49e-02 GO:0031974 membrane-enclosed lumen
1.06 1.53e-02 GO:0005737 cytoplasm
1.16 1.70e-02 GO:0031981 nuclear lumen
1.15 1.71e-02 GO:0044428 nuclear part
1.08 3.45e-02 GO:0044422 organelle part
1.08 4.02e-02 GO:0044446 intracellular organelle part
1.07 4.55e-02 GO:0044444 cytoplasmic part
1.13 4.67e-02 GO:0043233 organelle lumen
1.58 4.83e-02 GO:0009897 external side of plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 1.09e-11 GO:0005515 protein binding
1.30 4.06e-04 GO:0003723 RNA binding
1.04 8.39e-04 GO:0005488 binding
1.58 2.77e-03 GO:0005125 cytokine activity
1.59 3.55e-03 GO:0005126 cytokine receptor binding
1.12 1.19e-02 GO:0003676 nucleic acid binding
2.08 3.92e-02 GO:0003743 translation initiation factor activity