Motif ID: SRY.p2

Z-value: 1.230


Transcription factors associated with SRY.p2:

Gene SymbolEntrez IDGene Name
SRY 6736 sex determining region Y



Activity profile for motif SRY.p2.

activity profile for motif SRY.p2


Sorted Z-values histogram for motif SRY.p2

Sorted Z-values for motif SRY.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SRY.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_82557956 3.167 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chrX_-_19598912 2.648 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr12_-_101115677 2.377 NM_002674
PMCH
pro-melanin-concentrating hormone
chrX_-_138742050 2.326 NM_001010986
NM_173694
ATP11C

ATPase, class VI, type 11C

chr13_-_32678142 2.311 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr9_-_8723893 2.241 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr2_-_39310176 2.089 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr13_+_23742846 2.037 SPATA13
spermatogenesis associated 13
chr3_-_11598829 2.000 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr3_-_150533948 1.915 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr12_-_7487989 1.884 NM_174941
CD163L1
CD163 molecule-like 1
chr1_-_177106702 1.829 NM_004673
ANGPTL1
angiopoietin-like 1
chr10_-_31328426 1.793 NM_001143769
ZNF438
zinc finger protein 438
chr6_-_76259976 1.773 NM_015687
FILIP1
filamin A interacting protein 1
chr9_+_27099138 1.723 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr4_-_101658094 1.653 NM_001159694
NM_016242
EMCN

endomucin

chr4_-_74307637 1.576 ANKRD17
ankyrin repeat domain 17
chr8_-_108579270 1.573 NM_001146
ANGPT1
angiopoietin 1
chr1_-_171286634 1.556 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr13_-_98708549 1.555 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr9_-_16717887 1.531 BNC2
basonuclin 2
chr11_+_36274300 1.497 NM_001160167
PRR5L
proline rich 5 like
chr2_-_231697999 1.486 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr18_+_3584056 1.467 FLJ35776
hypothetical LOC649446
chr13_-_32658215 1.452 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr4_-_186934059 1.449 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr1_+_66570363 1.449 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr8_-_93144366 1.443 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_179736917 1.423 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr2_-_202271598 1.404 NM_033066
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr7_+_134483305 1.394 NM_018295
TMEM140
transmembrane protein 140
chrX_+_135079120 1.394 NM_001159704
FHL1
four and a half LIM domains 1
chr8_+_40130143 1.387 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr7_+_106293112 1.379 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr11_-_101292462 1.372 NM_178127
ANGPTL5
angiopoietin-like 5
chr18_+_64616296 1.369 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr16_+_14187965 1.358 MKL2
MKL/myocardin-like 2
chr8_-_13416554 1.356 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr5_-_111119846 1.348 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr6_-_56615544 1.344 NM_001723
NM_015548
DST

dystonin

chr4_+_141397889 1.343 NM_032547
SCOC
short coiled-coil protein
chr13_+_51933228 1.330 CKAP2
cytoskeleton associated protein 2
chr12_+_26096757 1.302 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr6_-_56824672 1.302 DST
dystonin
chr5_-_83052606 1.289 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr6_-_139654807 1.277 NM_153235
TXLNB
taxilin beta
chr17_-_64649608 1.266 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr20_+_10363949 1.266 NM_001009608
C20orf94
chromosome 20 open reading frame 94
chr7_+_102340579 1.247 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr8_-_93181091 1.244 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_225519974 1.240 DOCK10
dedicator of cytokinesis 10
chr2_+_36777336 1.227 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr3_-_115825742 1.225 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chrX_-_44945025 1.221 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr6_-_111995213 1.220 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr11_+_57547928 1.216 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr14_-_22358752 1.211 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr7_-_27125738 1.206 NM_030661
HOXA3
homeobox A3
chr2_-_175337386 1.198 NM_000079
NM_001039523
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr17_+_55098280 1.193 CLTC
clathrin, heavy chain (Hc)
chr7_-_83662152 1.176 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_+_120148604 1.169 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr21_+_29439768 1.162 C21orf7
chromosome 21 open reading frame 7
chr8_-_133841988 1.160 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chr19_-_53444733 1.141 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr8_+_32623792 1.140 NM_013959
NRG1
neuregulin 1
chr5_+_76470829 1.132


chr15_+_37330176 1.128 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr3_-_167037861 1.118 BCHE
butyrylcholinesterase
chr4_+_160408447 1.117 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr3_+_173043832 1.114 NM_001164436
TMEM212
transmembrane protein 212
chr6_-_87861492 1.099 NM_000735
CGA
glycoprotein hormones, alpha polypeptide
chr18_+_7936885 1.093 PTPRM
protein tyrosine phosphatase, receptor type, M
chr1_+_43539239 1.090 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr6_+_130381408 1.071 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr6_-_134540666 1.066 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr4_+_86918870 1.040 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr7_+_80105858 1.029 CD36
CD36 molecule (thrombospondin receptor)
chr12_+_50592379 1.026 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr1_+_242281199 1.025 ZNF238
zinc finger protein 238
chr15_-_32398220 1.008 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chrX_+_135079461 1.007 NM_001167819
FHL1
four and a half LIM domains 1
chr7_-_143213296 1.007 FAM115A
family with sequence similarity 115, member A
chr5_+_38439399 1.005 NM_182798
NM_182799
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr3_+_173954940 1.003 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr17_-_1195096 1.002 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr14_-_67353046 0.994 NM_015346
ZFYVE26
zinc finger, FYVE domain containing 26
chr1_+_242281175 0.991 NM_205768
ZNF238
zinc finger protein 238
chr3_+_133798770 0.990 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr7_-_41709191 0.986 NM_002192
INHBA
inhibin, beta A
chr12_-_110410730 0.982 ATXN2
ataxin 2
chr18_+_53863865 0.981 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr3_-_130761967 0.974 PLXND1
plexin D1
chr4_-_38482805 0.969 NM_003263
TLR1
toll-like receptor 1
chr8_-_18710575 0.969 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr9_+_674193 0.968


chr2_+_110013297 0.965 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr10_+_86174665 0.959 FAM190B
family with sequence similarity 190, member B
chr1_+_81544432 0.943 LPHN2
latrophilin 2
chr7_+_28692122 0.942 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr5_+_147775652 0.938 FBXO38
F-box protein 38
chr5_-_71838875 0.932 NM_152625
ZNF366
zinc finger protein 366
chr15_-_68781662 0.930 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_-_90097384 0.924 NM_133503
DCN
decorin
chr1_+_84539876 0.921 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr4_-_170314382 0.917 SH3RF1
SH3 domain containing ring finger 1
chr12_-_6668085 0.889 NM_001039916
ZNF384
zinc finger protein 384
chr4_+_114433551 0.884 ANK2
ankyrin 2, neuronal
chr2_+_33514896 0.884 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr20_-_7869068 0.882 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr5_-_88155360 0.876 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr3_-_69212192 0.876 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr4_+_86918882 0.872 ARHGAP24
Rho GTPase activating protein 24
chrX_-_77801480 0.868 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chrX_-_19727828 0.865 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr2_+_108637698 0.863 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_+_152970904 0.850 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr17_-_64568641 0.849 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr4_-_68432293 0.839 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chr2_+_108571336 0.838 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_+_144654565 0.836 NM_007124
UTRN
utrophin
chrX_-_19727775 0.835 SH3KBP1
SH3-domain kinase binding protein 1
chr10_-_61819493 0.833 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr20_+_19818209 0.833 NM_018993
RIN2
Ras and Rab interactor 2
chr3_-_58627509 0.832 NM_138805
FAM3D
family with sequence similarity 3, member D
chr17_+_65009986 0.828 MAP2K6
mitogen-activated protein kinase kinase 6
chr6_-_46997579 0.825 NM_001098518
GPR116
G protein-coupled receptor 116
chr11_+_129496792 0.824 APLP2
amyloid beta (A4) precursor-like protein 2
chr12_-_55990512 0.820 NM_014925
R3HDM2
R3H domain containing 2
chr4_-_104240413 0.817 NM_020139
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr21_+_39117064 0.808 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr2_-_198248828 0.804 NM_144629
RFTN2
raftlin family member 2
chr10_+_104995633 0.803 NM_001143909
LOC729020
rcRPE
chr2_-_37727472 0.802 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chrX_-_99778340 0.802 NM_003270
TSPAN6
tetraspanin 6
chrX_-_43717864 0.800 NM_000266
NDP
Norrie disease (pseudoglioma)
chr3_-_167037946 0.799 NM_000055
BCHE
butyrylcholinesterase
chr19_-_14121728 0.794 LPHN1
latrophilin 1
chr5_-_137099602 0.792 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr10_-_91092410 0.790 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr2_-_110665188 0.786 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr5_-_178977441 0.783 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr11_+_101488380 0.782 NM_001195045
YAP1
Yes-associated protein 1
chr8_-_93176819 0.779 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr20_+_31613800 0.778 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr8_+_39890484 0.773 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr4_-_139382672 0.772 NM_014331
SLC7A11
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr11_-_17147863 0.772 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr20_+_23293020 0.770 NM_022482
GZF1
GDNF-inducible zinc finger protein 1
chr3_-_158703821 0.764 NM_001167911
NM_001167912
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr18_+_70471906 0.762 NM_001146189
NM_001146190
NM_017757
ZNF407


zinc finger protein 407


chr3_+_153468518 0.761 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr7_+_80105718 0.757 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr6_-_119137923 0.755 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr7_+_143263191 0.751 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr12_-_52281050 0.749 NM_001130059
ATF7
activating transcription factor 7
chr2_+_108637916 0.746 LIMS1
LIMS3
LIM and senescent cell antigen-like domains 1
LIM and senescent cell antigen-like domains 3
chr21_-_38792173 0.740 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr17_-_18890963 0.739 NM_006613
GRAP
GRB2-related adaptor protein
chr1_+_190811479 0.730 NM_002922
RGS1
regulator of G-protein signaling 1
chr11_+_117762432 0.727 UBE4A
ubiquitination factor E4A (UFD2 homolog, yeast)
chr7_+_134114912 0.720 CALD1
caldesmon 1
chr5_+_34720368 0.718 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr3_+_120799411 0.709 NM_015900
PLA1A
phospholipase A1 member A
chr12_+_76749199 0.707 NM_014903
NAV3
neuron navigator 3
chr2_+_183290912 0.706 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr9_+_115382990 0.706 RGS3
regulator of G-protein signaling 3
chr14_-_30927931 0.706 NM_015473
HEATR5A
HEAT repeat containing 5A
chr2_-_192420168 0.705 NM_004657
SDPR
serum deprivation response
chr12_-_69317441 0.704 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr1_+_242283129 0.699 NM_006352
ZNF238
zinc finger protein 238
chr11_-_3759886 0.697 NUP98
nucleoporin 98kDa
chr5_-_98290117 0.695 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr4_+_72321113 0.691 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr4_+_95898098 0.690 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr17_-_52248248 0.690 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr1_+_84540921 0.686 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr17_-_26672757 0.685 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr1_-_21288259 0.685 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr6_-_112186977 0.683 NM_153048
FYN
FYN oncogene related to SRC, FGR, YES
chr4_+_2853434 0.681 ADD1
adducin 1 (alpha)
chr3_+_148593911 0.676


chr20_+_56369012 0.674


chr3_+_69895651 0.665 NM_006722
MITF
microphthalmia-associated transcription factor
chr5_+_36642424 0.664 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_36642213 0.658 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr18_+_71051713 0.656 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr5_-_111340421 0.654 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr7_-_158304062 0.651 ESYT2
extended synaptotagmin-like protein 2
chr5_-_38631263 0.650 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr10_-_98315090 0.643 TM9SF3
transmembrane 9 superfamily member 3
chr11_-_121492010 0.643 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr10_-_116434364 0.643 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr7_-_115458047 0.643 TFEC
transcription factor EC
chr15_-_70838703 0.643


chr19_-_11166186 0.643 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr6_+_21774624 0.642 FLJ22536
hypothetical locus LOC401237
chr7_-_139948780 0.641 NM_015689
DENND2A
DENN/MADD domain containing 2A
chr13_-_47885653 0.641 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr22_+_34107051 0.640 NM_002133
HMOX1
heme oxygenase (decycling) 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 4.60e-03 GO:0071840 cellular component organization or biogenesis
1.18 1.52e-02 GO:0016043 cellular component organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 8.73e-03 GO:0005634 nucleus
1.21 1.30e-02 GO:0044428 nuclear part
1.23 2.48e-02 GO:0031981 nuclear lumen
1.26 3.57e-02 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 1.16e-02 GO:0005515 protein binding