Motif ID: STAT5{A,B}.p2

Z-value: 0.958


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B



Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_203503214 2.330 TMCC2
transmembrane and coiled-coil domain family 2
chr19_+_49361054 1.976 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
 ZNF226




zinc finger protein 226




chr19_+_49309350 1.771 NM_013362
 ZNF225
zinc finger protein 225
chr3_+_66094324 1.664 NM_173471
 SLC25A26
solute carrier family 25, member 26
chr1_-_206125877 1.594


chr19_-_53941835 1.585 NM_182575
 IZUMO1
izumo sperm-egg fusion 1
chr13_+_51334117 1.483 NM_031290
 CCDC70
coiled-coil domain containing 70
chr19_+_49290319 1.383 NM_013398
 ZNF224
zinc finger protein 224
chr4_-_77176163 1.337 NM_005409
 CXCL11
chemokine (C-X-C motif) ligand 11
chr14_-_19951417 1.298 NM_007110
 TEP1
telomerase-associated protein 1
chr3_+_171422940 1.287 PRKCI
protein kinase C, iota
chr11_+_36572615 1.286 NM_138787
 C11orf74
chromosome 11 open reading frame 74
chr19_+_49180171 1.204 NM_003445
NM_198089
 ZNF155

zinc finger protein 155

chr19_+_49408523 1.200 NM_182490
 ZNF227
zinc finger protein 227
chr2_+_95195260 1.187 ZNF2
zinc finger protein 2
chr3_+_171422917 1.155 PRKCI
protein kinase C, iota
chr19_-_49500966 1.129 NM_004234
 ZNF235
zinc finger protein 235
chr19_+_42400908 1.103 ZNF383
zinc finger protein 383
chr19_+_49248003 1.076 NM_013361
 ZNF223
zinc finger protein 223
chr8_-_66708954 1.044 ARMC1
armadillo repeat containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.76 2.31e-03 GO:0006355 regulation of transcription, DNA-dependent
1.75 7.37e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.73 1.01e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.70 8.49e-03 GO:0051252 regulation of RNA metabolic process
1.67 1.93e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.66 3.44e-03 GO:0009889 regulation of biosynthetic process
1.66 6.10e-03 GO:0010468 regulation of gene expression
1.65 1.41e-04 GO:0060255 regulation of macromolecule metabolic process
1.65 4.30e-03 GO:0031326 regulation of cellular biosynthetic process
1.61 1.52e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.55 3.15e-03 GO:0031323 regulation of cellular metabolic process
1.52 1.01e-02 GO:0080090 regulation of primary metabolic process
1.50 4.45e-03 GO:0019222 regulation of metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.49 1.46e-06 GO:0005634 nucleus
1.30 1.13e-05 GO:0043231 intracellular membrane-bounded organelle
1.30 1.26e-05 GO:0043227 membrane-bounded organelle
1.26 1.93e-05 GO:0043229 intracellular organelle
1.26 2.33e-05 GO:0043226 organelle
1.18 1.31e-03 GO:0044424 intracellular part
1.16 6.83e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
9.08 4.44e-02 GO:0015035 protein disulfide oxidoreductase activity
2.01 4.09e-07 GO:0008270 zinc ion binding
1.84 1.09e-05 GO:0046914 transition metal ion binding
1.79 4.65e-05 GO:0003677 DNA binding
1.49 8.42e-03 GO:0003676 nucleic acid binding