Motif ID: TBP.p2

Z-value: 1.617


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein



Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_36469869 4.003 NM_001165252
 LOC730755
keratin associated protein 2-4-like
chr21_-_44795769 3.438 NM_198693
 KRTAP10-2
keratin associated protein 10-2
chr1_+_151596953 3.396 NM_002965
 S100A9
S100 calcium binding protein A9
chr10_+_88770025 3.309 NM_001146157
 FAM25A
family with sequence similarity 25, member A
chr12_-_51173238 3.216 NM_005554
 KRT6A
keratin 6A
chr9_+_129951552 3.094 NM_005564
 LCN2
lipocalin 2
chr1_-_151630168 2.992 NM_002964
 S100A8
S100 calcium binding protein A8
chr1_+_150997129 2.894 NM_001025231
 KPRP
keratinocyte proline-rich protein
chr17_-_37034288 2.879 NM_000422
 KRT17
keratin 17
chr12_-_51153788 2.809 NM_173086
 KRT6C
keratin 6C
chr10_+_47867667 2.665 NM_001137556
NM_001137549
NM_001137548
 FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr1_+_151147646 2.494 NM_005547
 IVL
involucrin
chr8_-_6722848 2.454 NM_005218
 DEFB1
defensin, beta 1
chr11_+_1064869 2.444 NM_002457
 MUC2
mucin 2, oligomeric mucus/gel-forming
chr3_+_150675169 2.414 TM4SF4
transmembrane 4 L six family member 4
chr11_-_102219450 2.377 NM_002422
 MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr17_-_36436979 2.363 NM_031957
 KRTAP1-5
keratin associated protein 1-5
chr16_-_11277806 2.333 NM_002762
 PRM2
protamine 2
chr1_-_151784889 2.332 NM_002961
NM_019554
 S100A4

S100 calcium binding protein A4

chr10_-_46601687 2.207 NM_001137556
NM_001137549
NM_001137548
 FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
enrichment   p-value GO term description
10.91 1.69e-02 GO:0045104 intermediate filament cytoskeleton organization
10.82 3.14e-03 GO:0045103 intermediate filament-based process
9.83 6.54e-03 GO:0034367 macromolecular complex remodeling
9.83 6.54e-03 GO:0034368 protein-lipid complex remodeling
9.83 6.54e-03 GO:0034369 plasma lipoprotein particle remodeling
9.57 6.08e-07 GO:0031424 keratinization
8.32 2.26e-02 GO:0071825 protein-lipid complex subunit organization
8.32 2.26e-02 GO:0071827 plasma lipoprotein particle organization
8.01 2.97e-02 GO:0044243 multicellular organismal catabolic process
7.73 3.85e-02 GO:0032963 collagen metabolic process
7.73 3.85e-02 GO:0070301 cellular response to hydrogen peroxide
6.87 2.52e-02 GO:0044236 multicellular organismal metabolic process
6.62 1.01e-02 GO:0034614 cellular response to reactive oxygen species
6.31 1.60e-07 GO:0006334 nucleosome assembly
6.28 1.64e-04 GO:0030216 keratinocyte differentiation
6.26 1.73e-05 GO:0009913 epidermal cell differentiation
6.00 1.35e-07 GO:0034728 nucleosome organization
5.99 4.14e-07 GO:0031497 chromatin assembly
5.49 1.99e-06 GO:0065004 protein-DNA complex assembly
5.20 5.17e-06 GO:0071824 protein-DNA complex subunit organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
13.91 1.92e-30 GO:0045095 keratin filament
13.24 1.46e-06 GO:0001533 cornified envelope
12.02 1.65e-04 GO:0032982 myosin filament
10.55 6.18e-41 GO:0005882 intermediate filament
9.97 4.93e-13 GO:0000786 nucleosome
9.13 5.79e-37 GO:0045111 intermediate filament cytoskeleton
8.58 4.27e-02 GO:0005859 muscle myosin complex
6.37 5.15e-09 GO:0032993 protein-DNA complex
5.35 7.55e-03 GO:0031983 vesicle lumen
3.73 4.27e-03 GO:0030016 myofibril
3.56 1.40e-02 GO:0044449 contractile fiber part
3.52 8.31e-03 GO:0043292 contractile fiber
3.24 8.78e-19 GO:0005615 extracellular space
3.05 3.71e-04 GO:0000785 chromatin
2.95 1.58e-19 GO:0044421 extracellular region part
2.57 4.01e-04 GO:0031012 extracellular matrix
2.53 3.65e-03 GO:0005578 proteinaceous extracellular matrix
2.49 1.89e-12 GO:0044430 cytoskeletal part
2.31 4.67e-21 GO:0005576 extracellular region
2.15 7.47e-12 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
7.18 1.72e-11 GO:0005179 hormone activity
6.47 2.39e-03 GO:0008307 structural constituent of muscle
4.79 4.96e-03 GO:0005200 structural constituent of cytoskeleton
3.57 1.14e-17 GO:0005198 structural molecule activity
2.29 9.26e-09 GO:0005102 receptor binding