Motif ID: TFDP1.p2

Z-value: 1.673

Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1

Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2

Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2

Network of associatons between targets according to the STRING database.

First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:

Promoter Score Refseq Gene Symbol Gene Name
chr12_+_52060191 1.259 NM_138473
Sp1 transcription factor
chr3_-_137953876 1.208 NM_005862
stromal antigen 1
chr18_-_50004770 1.046 MBD2
methyl-CpG binding domain protein 2
chr14_-_20636337 1.015 ZNF219
zinc finger protein 219
chr8_-_103735194 1.012 NM_001032282
Kruppel-like factor 10
chr3_+_43303005 1.002 NM_001100594

SNF related kinase

chr3_-_14964620 0.997

chr17_+_62391216 0.988 NM_014405
calcium channel, voltage-dependent, gamma subunit 4
chr4_+_129951877 0.986 PHF17
PHD finger protein 17
chr2_+_203208456 0.971 FAM117B
family with sequence similarity 117, member B
chr20_-_3714905 0.965 NM_001810
centromere protein B, 80kDa
chr5_+_154115046 0.963 LARP1
La ribonucleoprotein domain family, member 1
chr7_-_22363036 0.944 NM_012294
Rap guanine nucleotide exchange factor (GEF) 5
chr6_-_18372617 0.939 NM_001134709

DEK oncogene

chr10_+_82203872 0.934 NM_001128309

tetraspanin 14

chr7_-_27149750 0.931 NM_019102
homeobox A5
chr18_-_50004458 0.915 MBD2
methyl-CpG binding domain protein 2
chr7_-_28186671 0.895 JAZF1
JAZF zinc finger 1
chr20_-_39379533 0.891 ZHX3
zinc fingers and homeoboxes 3
chr6_+_44346457 0.869 NM_001137560
transmembrane protein 151B
chr6_-_112301123 0.858 NM_002037
FYN oncogene related to SRC, FGR, YES
chr6_-_107542328 0.849 NM_001080450
BEN domain containing 3
chr10_+_22649977 0.843 NM_005180
BMI1 polycomb ring finger oncogene
chr12_+_52060689 0.839 NM_003109
Sp1 transcription factor
chr11_+_32870935 0.835 NM_001076786
glutamine and serine rich 1
chr9_-_101621964 0.833

chr9_-_112840064 0.829 NM_001401

lysophosphatidic acid receptor 1

chr3_-_114898003 0.820 NM_001009899
chr12_-_122322117 0.814 NM_004642
cyclin-dependent kinase 2 associated protein 1
chr16_+_29725311 0.791 NM_001042539

MYC-associated zinc finger protein (purine-binding transcription factor)

chr1_+_144188375 0.783 NM_153713
Lix1 homolog (mouse)-like
chr2_-_165186064 0.783 GRB14
growth factor receptor-bound protein 14
chr20_-_49592444 0.779 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr2_+_223433919 0.773 NM_004457

acyl-CoA synthetase long-chain family member 3

chr16_-_48960186 0.771 NM_001173984

bromodomain containing 7

chr18_-_50004932 0.754 MBD2
methyl-CpG binding domain protein 2
chr1_+_46041870 0.753 NM_015112
microtubule associated serine/threonine kinase 2
chr20_-_49592654 0.747 NM_012340

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

chr3_-_169295752 0.745 GOLIM4
golgi integral membrane protein 4
chr9_+_130354490 0.743 NM_001130438

spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)

chr16_+_21926939 0.736 NM_001164579
chromosome 16 open reading frame 52
chr6_+_148705421 0.730 NM_015278
SAM and SH3 domain containing 1
chr17_+_31975611 0.723 GGNBP2
gametogenetin binding protein 2
chr2_+_36436316 0.715 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr2_-_213724577 0.713 NM_001079526
IKAROS family zinc finger 2 (Helios)
chr20_+_13924263 0.711 MACROD2
MACRO domain containing 2
chr15_+_83092854 0.709 ZNF592
zinc finger protein 592
chr3_+_37878647 0.706 NM_001008392

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr18_-_50004996 0.705 NM_003927

methyl-CpG binding domain protein 2

chr2_+_159533329 0.702 NM_001145909

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr17_-_60088773 0.697 NM_022739
SMAD specific E3 ubiquitin protein ligase 2
chr3_-_14964861 0.695 LOC100505673
hypothetical LOC100505673
chr11_-_75769514 0.693 NM_004705
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr22_-_32646325 0.690 NM_004737


chr1_-_37752925 0.683 NM_022756
MYST/Esa1-associated factor 6
chr10_+_83625049 0.682 NM_001010848

neuregulin 3

chr1_+_42920946 0.682 YBX1
Y box binding protein 1
chr18_-_72336133 0.681 NM_014643
zinc finger protein 516
chr2_-_160972606 0.681 RBMS1
RNA binding motif, single stranded interacting protein 1
chr22_-_37043330 0.681 NM_152221
casein kinase 1, epsilon
chr1_-_93199586 0.679 NM_001006605
family with sequence similarity 69, member A
chr14_+_61231795 0.677 NM_001530

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr20_-_3944035 0.676 NM_007219

ring finger protein 24

chr16_-_67977041 0.673 TERF2
telomeric repeat binding factor 2
chr1_-_242681860 0.669 NM_001126
adenylosuccinate synthase
chr14_-_34001164 0.665 NM_138288
chromosome 14 open reading frame 147
chr6_+_34312906 0.659 HMGA1
high mobility group AT-hook 1
chr22_-_37043396 0.654 CSNK1E
casein kinase 1, epsilon
chr5_+_52812165 0.638 FST
chr12_+_88627601 0.638 LOC338758
hypothetical LOC338758
chr18_-_43710917 0.635 NM_005901
SMAD family member 2
chr3_+_197780105 0.629 NM_001105573
F-box protein 45
chr6_+_52550063 0.627 FLJ37798
hypothetical LOC401264
chr7_-_138316393 0.626 NM_001164665


chr1_-_211255389 0.615 ANGEL2
angel homolog 2 (Drosophila)
chr10_-_25052549 0.613 NM_020824
Rho GTPase activating protein 21
chr3_-_52694554 0.610 NM_018313
polybromo 1
chr5_+_52812236 0.610 NM_006350


chr6_+_42857540 0.605 KIAA0240
chr3_+_39826032 0.602 NM_015460
myosin VIIA and Rab interacting protein
chr14_-_73323629 0.601 NM_001043318
chromosome 14 open reading frame 43
chr20_-_4930133 0.595 NM_005116
solute carrier family 23 (nucleobase transporters), member 2
chr22_-_30215725 0.594 EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr19_+_47480445 0.594 NM_015125
capicua homolog (Drosophila)
chr14_-_19999324 0.589 TMEM55B
transmembrane protein 55B
chr10_+_70257299 0.585 NM_001130159

storkhead box 1

chr22_+_33983444 0.582 NM_001003681
HMG box domain containing 4
chr19_-_36531958 0.574 NM_020856
teashirt zinc finger homeobox 3
chr22_-_34754343 0.570 NM_001082578

RNA binding protein, fox-1 homolog (C. elegans) 2

chr16_-_71639670 0.570 NM_006885
zinc finger homeobox 3
chr10_+_59942874 0.568 NM_001080512
bicaudal C homolog 1 (Drosophila)
chr4_+_146622154 0.567 NM_005900
SMAD family member 1
chr18_-_43711452 0.565 NM_001003652

SMAD family member 2

chr11_+_85633437 0.564 NM_003797

embryonic ectoderm development

chr3_-_187025438 0.563 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr6_-_99904251 0.561 NM_032511
chromosome 6 open reading frame 168
chr3_+_63825221 0.559 NM_000333
ataxin 7
chr2_-_215382537 0.558 NM_000465
BRCA1 associated RING domain 1
chr6_-_151754337 0.556 NM_020861
zinc finger and BTB domain containing 2
chr12_+_122439555 0.555 SETD8
SET domain containing (lysine methyltransferase) 8
chr2_+_64535114 0.555 HSPC159
galectin-related protein
chr22_-_30215512 0.554 NM_001164501
eukaryotic translation initiation factor 4E nuclear import factor 1
chr7_+_137795719 0.552 TRIM24
tripartite motif containing 24
chr17_+_35531742 0.549 MSL1
male-specific lethal 1 homolog (Drosophila)
chr10_+_82204046 0.548 TSPAN14
tetraspanin 14
chr10_+_82204051 0.547 TSPAN14
tetraspanin 14
chr17_-_70690625 0.546 SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr2_-_165186232 0.537 GRB14
growth factor receptor-bound protein 14
chr15_-_27901828 0.535 NM_003257

tight junction protein 1 (zona occludens 1)

chr21_+_43267760 0.535 PKNOX1
PBX/knotted 1 homeobox 1
chr20_+_41519882 0.532 NM_006275
serine/arginine-rich splicing factor 6
chr1_-_32176275 0.531 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr7_+_97748959 0.530 BRI3
brain protein I3
chr6_-_41971064 0.529 NM_018561
ubiquitin specific peptidase 49
chr11_-_3818759 0.525 NM_001665
ras homolog gene family, member G (rho G)
chr2_+_64534774 0.521 NM_014181
galectin-related protein
chr9_+_128416542 0.517 NM_001174146

LIM homeobox transcription factor 1, beta

chr20_+_56397695 0.517 VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr14_-_29466562 0.517 NM_002742
protein kinase D1
chr14_+_31616196 0.516 NM_001030055

Rho GTPase activating protein 5

chr10_-_131652007 0.516 NM_001005463
early B-cell factor 3
chr14_-_90596484 0.513

chr3_-_49105905 0.513 QRICH1
glutamine-rich 1
chr3_-_187025501 0.511 NM_001007225

insulin-like growth factor 2 mRNA binding protein 2

chr7_+_77004267 0.510 PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr1_-_210070199 0.508 LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr3_+_112273464 0.507 NM_015480
poliovirus receptor-related 3
chr8_-_103494073 0.506 UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr19_-_13977875 0.501 RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr2_+_181553613 0.499 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr2_+_203208064 0.499 NM_173511
family with sequence similarity 117, member B
chr10_+_105716925 0.499 SLK
STE20-like kinase
chr2_+_85051687 0.497 NM_020122
potassium channel modulatory factor 1
chr20_-_51644187 0.497 ZNF217
zinc finger protein 217
chr16_+_29725597 0.497

chr4_+_57468847 0.496 REST
RE1-silencing transcription factor
chr15_-_99609197 0.495 CHSY1
chondroitin sulfate synthase 1
chr6_-_163754903 0.492 LOC100526820
hypothetical LOC100526820
chr7_+_97748914 0.491 NM_001159491

brain protein I3

chr18_-_71050268 0.490 NM_175907
zinc binding alcohol dehydrogenase domain containing 2
chr2_+_149118791 0.490 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr3_-_53054325 0.489 NM_001005159
Scm-like with four mbt domains 1
chr7_-_141048358 0.488 NM_001080392
chr19_-_44032415 0.487 HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr6_+_90596348 0.485 CASP8AP2
caspase 8 associated protein 2
chr22_+_49293520 0.485 NCAPH2
non-SMC condensin II complex, subunit H2
chr1_-_153509473 0.485 NM_003993
CDC-like kinase 2
chr1_-_242681742 0.485 ADSS
adenylosuccinate synthase
chr3_-_14963943 0.485

chr2_-_39201631 0.484 SOS1
son of sevenless homolog 1 (Drosophila)
chrX_-_16797895 0.476 NM_001198719
retinoblastoma binding protein 7
chr6_-_41855564 0.476 NM_006653
fibroblast growth factor receptor substrate 3
chr1_-_204048758 0.475 NM_173854
solute carrier family 41, member 1
chr3_+_52694975 0.472 NM_014366

guanine nucleotide binding protein-like 3 (nucleolar)

chr11_+_85633908 0.472 EED
embryonic ectoderm development
chr7_+_17304707 0.470 NM_001621
aryl hydrocarbon receptor
chr1_+_42920755 0.468 YBX1
Y box binding protein 1
chr4_+_38722593 0.468 NM_001007075

kelch-like 5 (Drosophila)

chr17_-_46140015 0.468 NM_052855
ankyrin repeat domain 40
chr2_-_69467825 0.466 NM_002056
glutamine--fructose-6-phosphate transaminase 1
chr8_-_81246215 0.464 NM_001025253

tumor protein D52

chr19_-_52426055 0.464 NM_014417
BCL2 binding component 3
chr11_-_109672401 0.464 NM_002906
chr16_+_29724926 0.461 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_+_57909979 0.460 NM_001112707

tousled-like kinase 2

chr13_+_102047286 0.458 NM_003291
tripeptidyl peptidase II
chr14_-_90596665 0.457 NM_004755

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr5_+_113726203 0.456 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr15_-_27901628 0.456 TJP1
tight junction protein 1 (zona occludens 1)
chr16_-_66827449 0.455 NM_024939
epithelial splicing regulatory protein 2
chr12_+_124044187 0.451 BRI3BP
BRI3 binding protein
chr10_+_82204054 0.451 TSPAN14
tetraspanin 14
chr5_+_72957736 0.451 NM_001080479

190 kDa guanine nucleotide exchange factor

chr17_-_60088637 0.450 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr12_+_56202874 0.448 NM_052897
methyl-CpG binding domain protein 6
chr6_+_135544214 0.447 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr11_-_59193064 0.446 NM_152716
protein associated with topoisomerase II homolog 1 (yeast)
chr18_-_43711143 0.445 SMAD2
SMAD family member 2
chr17_-_24940521 0.445 GIT1
G protein-coupled receptor kinase interacting ArfGAP 1
chr5_-_65053630 0.445 NM_019072
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr12_-_110521743 0.445 NM_002973
ataxin 2
chr17_+_5126275 0.444 NM_001083585

rabaptin, RAB GTPase binding effector protein 1

chr12_-_105165805 0.443 NM_006825
cytoskeleton-associated protein 4
chr4_-_15837195 0.441 NM_153365
transmembrane anterior posterior transformation 1
chr10_-_123347493 0.441 NM_000141

fibroblast growth factor receptor 2

chr7_-_105712646 0.441 NM_005746
nicotinamide phosphoribosyltransferase
chr13_+_25726238 0.440 CDK8
cyclin-dependent kinase 8
chr15_-_73531082 0.440 NM_001145358
SIN3 homolog A, transcription regulator (yeast)
chr4_-_78959532 0.440 NM_144571
CCR4-NOT transcription complex, subunit 6-like
chr11_-_59192942 0.439 PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr2_+_54536780 0.438 NM_003128
spectrin, beta, non-erythrocytic 1
chr3_+_134775404 0.437 CDV3
CDV3 homolog (mouse)
chr17_-_17667580 0.429 SREBF1
sterol regulatory element binding transcription factor 1
chr3_+_123996560 0.429 NM_032839
disrupted in renal carcinoma 2
chr2_-_210744158 0.429 NM_152519
chromosome 2 open reading frame 67
chr10_+_92970302 0.429 NM_032373
polycomb group ring finger 5
chr17_-_2153561 0.427 NM_001170957
Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr3_+_50167424 0.427 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr17_+_7728819 0.426 NM_001005271
chromodomain helicase DNA binding protein 3
chr6_+_56927665 0.423 NM_152731
BEN domain containing 6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.28 1.63e-44 GO:0044260 cellular macromolecule metabolic process
1.20 6.81e-37 GO:0044237 cellular metabolic process
1.11 5.15e-36 GO:0009987 cellular process
1.22 5.39e-32 GO:0043170 macromolecule metabolic process
1.34 1.16e-31 GO:0044267 cellular protein metabolic process
1.40 2.76e-30 GO:0006464 protein modification process
1.17 7.07e-28 GO:0044238 primary metabolic process
1.37 5.16e-27 GO:0043412 macromolecule modification
1.30 1.02e-25 GO:0071842 cellular component organization at cellular level
1.15 1.90e-25 GO:0008152 metabolic process
1.39 4.85e-25 GO:0006996 organelle organization
1.29 1.26e-24 GO:0071841 cellular component organization or biogenesis at cellular level
1.25 1.85e-23 GO:0016043 cellular component organization
1.15 2.69e-22 GO:0050794 regulation of cellular process
1.24 2.70e-22 GO:0071840 cellular component organization or biogenesis
1.25 8.92e-20 GO:0019538 protein metabolic process
1.13 1.88e-19 GO:0050789 regulation of biological process
1.25 1.95e-18 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 2.95e-18 GO:0031323 regulation of cellular metabolic process
1.55 2.71e-17 GO:0051276 chromosome organization
1.12 3.42e-17 GO:0065007 biological regulation
1.21 1.58e-16 GO:0080090 regulation of primary metabolic process
1.19 4.85e-16 GO:0019222 regulation of metabolic process
1.25 1.37e-15 GO:0048522 positive regulation of cellular process
1.21 1.49e-15 GO:0060255 regulation of macromolecule metabolic process
1.21 2.85e-15 GO:0006807 nitrogen compound metabolic process
1.21 5.23e-15 GO:0034641 cellular nitrogen compound metabolic process
1.30 2.18e-14 GO:0034645 cellular macromolecule biosynthetic process
1.30 2.30e-14 GO:0009059 macromolecule biosynthetic process
1.26 2.61e-14 GO:0090304 nucleic acid metabolic process
1.22 1.11e-13 GO:0048518 positive regulation of biological process
1.37 4.03e-13 GO:0007049 cell cycle
1.55 8.85e-13 GO:0006325 chromatin organization
1.62 1.35e-12 GO:0016568 chromatin modification
1.23 2.23e-12 GO:0044249 cellular biosynthetic process
1.22 2.25e-12 GO:0009058 biosynthetic process
1.24 4.49e-12 GO:0048523 negative regulation of cellular process
1.36 1.88e-11 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.21 4.38e-11 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 4.58e-11 GO:0048519 negative regulation of biological process
1.39 6.05e-11 GO:0051128 regulation of cellular component organization
1.20 1.08e-10 GO:0051171 regulation of nitrogen compound metabolic process
1.38 1.63e-10 GO:0033554 cellular response to stress
1.32 2.02e-10 GO:0010604 positive regulation of macromolecule metabolic process
1.38 2.09e-10 GO:0022402 cell cycle process
1.80 2.21e-10 GO:0016569 covalent chromatin modification
1.45 2.93e-10 GO:0000278 mitotic cell cycle
1.21 3.62e-10 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.30 4.01e-10 GO:0009893 positive regulation of metabolic process
1.80 4.17e-10 GO:0016570 histone modification
1.26 7.36e-10 GO:0023051 regulation of signaling
1.30 1.03e-09 GO:0031325 positive regulation of cellular metabolic process
1.27 2.43e-09 GO:0009966 regulation of signal transduction
1.55 3.62e-09 GO:0018193 peptidyl-amino acid modification
1.32 5.22e-09 GO:0006793 phosphorus metabolic process
1.32 5.22e-09 GO:0006796 phosphate metabolic process
1.28 5.91e-09 GO:0033036 macromolecule localization
1.19 9.66e-09 GO:0010468 regulation of gene expression
1.23 1.44e-08 GO:0010467 gene expression
1.19 1.52e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.55 1.74e-08 GO:0070647 protein modification by small protein conjugation or removal
1.40 2.39e-08 GO:0051726 regulation of cell cycle
1.30 2.87e-08 GO:0008104 protein localization
1.38 3.26e-08 GO:0022403 cell cycle phase
1.33 3.48e-08 GO:0006351 transcription, DNA-dependent
1.18 4.68e-08 GO:0031326 regulation of cellular biosynthetic process
1.35 5.91e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.36 7.01e-08 GO:0006468 protein phosphorylation
1.38 7.12e-08 GO:0051254 positive regulation of RNA metabolic process
1.35 7.59e-08 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 1.11e-07 GO:0035556 intracellular signal transduction
1.51 1.17e-07 GO:0051301 cell division
1.31 1.17e-07 GO:0032774 RNA biosynthetic process
1.18 1.22e-07 GO:0009889 regulation of biosynthetic process
1.19 1.51e-07 GO:0051252 regulation of RNA metabolic process
1.49 1.74e-07 GO:0007264 small GTPase mediated signal transduction
1.30 1.96e-07 GO:0032268 regulation of cellular protein metabolic process
1.31 2.58e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.22 4.05e-07 GO:0016070 RNA metabolic process
1.38 4.27e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.36 4.89e-07 GO:0010628 positive regulation of gene expression
1.13 1.53e-06 GO:0051716 cellular response to stimulus
1.19 1.57e-06 GO:0006355 regulation of transcription, DNA-dependent
1.27 1.70e-06 GO:0051246 regulation of protein metabolic process
1.36 1.81e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.30 1.92e-06 GO:0045184 establishment of protein localization
1.54 2.09e-06 GO:0032446 protein modification by small protein conjugation
1.50 3.17e-06 GO:0019941 modification-dependent protein catabolic process
1.31 3.83e-06 GO:0046907 intracellular transport
1.55 4.94e-06 GO:0016567 protein ubiquitination
1.40 5.92e-06 GO:0031175 neuron projection development
1.49 5.93e-06 GO:0043632 modification-dependent macromolecule catabolic process
1.29 6.75e-06 GO:0031324 negative regulation of cellular metabolic process
1.29 7.66e-06 GO:0016265 death
1.48 8.07e-06 GO:0033043 regulation of organelle organization
1.49 8.85e-06 GO:0006511 ubiquitin-dependent protein catabolic process
1.29 9.23e-06 GO:0008219 cell death
1.50 1.05e-05 GO:0000280 nuclear division
1.50 1.05e-05 GO:0007067 mitosis
1.34 1.21e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.27 1.23e-05 GO:0009892 negative regulation of metabolic process
1.49 1.46e-05 GO:0000087 M phase of mitotic cell cycle
1.47 1.80e-05 GO:0051603 proteolysis involved in cellular protein catabolic process
1.34 1.97e-05 GO:0030030 cell projection organization
1.49 1.99e-05 GO:0048285 organelle fission
1.34 2.04e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 2.30e-05 GO:0015031 protein transport
1.35 2.40e-05 GO:0006259 DNA metabolic process
1.29 2.84e-05 GO:0016310 phosphorylation
1.32 3.41e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.33 4.46e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.40 4.74e-05 GO:0000279 M phase
1.45 5.15e-05 GO:0044257 cellular protein catabolic process
1.33 5.21e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.30 5.46e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.12 6.09e-05 GO:0032502 developmental process
1.31 6.11e-05 GO:0009890 negative regulation of biosynthetic process
1.27 8.49e-05 GO:0048468 cell development
1.27 1.48e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.22 1.51e-04 GO:0051641 cellular localization
1.27 1.55e-04 GO:0009891 positive regulation of biosynthetic process
1.34 2.23e-04 GO:0044265 cellular macromolecule catabolic process
1.12 2.66e-04 GO:0007165 signal transduction
1.33 2.68e-04 GO:0048666 neuron development
1.20 2.73e-04 GO:0007399 nervous system development
1.29 3.39e-04 GO:0012501 programmed cell death
1.20 3.42e-04 GO:0009653 anatomical structure morphogenesis
1.83 3.89e-04 GO:0018205 peptidyl-lysine modification
1.36 3.92e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.34 4.93e-04 GO:0006974 response to DNA damage stimulus
1.25 5.17e-04 GO:0022008 neurogenesis
1.34 5.22e-04 GO:0000904 cell morphogenesis involved in differentiation
1.27 5.35e-04 GO:0031399 regulation of protein modification process
1.33 5.62e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.56 5.64e-04 GO:0006260 DNA replication
1.37 5.95e-04 GO:0007409 axonogenesis
1.31 7.18e-04 GO:0010629 negative regulation of gene expression
1.40 7.32e-04 GO:0030163 protein catabolic process
1.36 8.27e-04 GO:0048812 neuron projection morphogenesis
1.43 8.69e-04 GO:0051329 interphase of mitotic cell cycle
1.32 9.35e-04 GO:0051253 negative regulation of RNA metabolic process
1.66 1.04e-03 GO:0051789 response to protein stimulus
1.12 1.09e-03 GO:0007275 multicellular organismal development
1.25 1.48e-03 GO:0048699 generation of neurons
1.21 1.62e-03 GO:0044248 cellular catabolic process
1.42 1.73e-03 GO:0051325 interphase
1.12 1.83e-03 GO:0048856 anatomical structure development
1.27 1.94e-03 GO:0006915 apoptosis
1.48 2.24e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.11 2.26e-03 GO:0051179 localization
1.63 2.26e-03 GO:0006470 protein dephosphorylation
1.11 2.39e-03 GO:0023052 signaling
1.32 2.65e-03 GO:0032990 cell part morphogenesis
1.91 2.89e-03 GO:0006479 protein methylation
1.91 2.89e-03 GO:0008213 protein alkylation
2.30 2.94e-03 GO:0034968 histone lysine methylation
1.32 3.21e-03 GO:0048858 cell projection morphogenesis
1.32 3.23e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.29 3.43e-03 GO:0000902 cell morphogenesis
2.10 3.55e-03 GO:0016571 histone methylation
1.42 3.83e-03 GO:0010608 posttranscriptional regulation of gene expression
1.76 3.95e-03 GO:0043543 protein acylation
2.07 3.96e-03 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
1.34 4.33e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.58 4.77e-03 GO:0016311 dephosphorylation
1.87 5.51e-03 GO:0030518 steroid hormone receptor signaling pathway
1.31 5.71e-03 GO:0070727 cellular macromolecule localization
1.53 5.99e-03 GO:0051493 regulation of cytoskeleton organization
1.49 6.11e-03 GO:0044087 regulation of cellular component biogenesis
1.30 8.28e-03 GO:0034613 cellular protein localization
1.40 8.32e-03 GO:0006366 transcription from RNA polymerase II promoter
1.22 8.47e-03 GO:0032879 regulation of localization
1.28 8.66e-03 GO:0009057 macromolecule catabolic process
1.45 8.82e-03 GO:0051129 negative regulation of cellular component organization
1.66 9.18e-03 GO:0007059 chromosome segregation
1.37 1.01e-02 GO:0006281 DNA repair
1.84 1.02e-02 GO:0006986 response to unfolded protein
1.64 1.30e-02 GO:0031098 stress-activated protein kinase signaling cascade
1.17 1.41e-02 GO:0065009 regulation of molecular function
1.20 1.46e-02 GO:0051649 establishment of localization in cell
1.61 1.53e-02 GO:0007265 Ras protein signal transduction
1.25 1.57e-02 GO:0019220 regulation of phosphate metabolic process
1.25 1.57e-02 GO:0051174 regulation of phosphorus metabolic process
1.45 1.62e-02 GO:0045786 negative regulation of cell cycle
1.12 1.63e-02 GO:0048731 system development
1.49 2.27e-02 GO:0051169 nuclear transport
1.25 2.32e-02 GO:0030182 neuron differentiation
1.34 2.36e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.49 2.51e-02 GO:0006913 nucleocytoplasmic transport
1.26 2.66e-02 GO:0032989 cellular component morphogenesis
1.75 2.75e-02 GO:0006473 protein acetylation
1.42 2.79e-02 GO:0006195 purine nucleotide catabolic process
1.36 2.85e-02 GO:0032535 regulation of cellular component size
1.14 2.93e-02 GO:0030154 cell differentiation
1.40 2.95e-02 GO:0009166 nucleotide catabolic process
1.58 3.06e-02 GO:0043254 regulation of protein complex assembly
1.79 3.33e-02 GO:0018394 peptidyl-lysine acetylation
1.28 3.44e-02 GO:0010942 positive regulation of cell death
1.81 3.47e-02 GO:0016573 histone acetylation
1.40 3.80e-02 GO:0072523 purine-containing compound catabolic process
1.38 3.84e-02 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.38 3.84e-02 GO:0034656 nucleobase, nucleoside and nucleotide catabolic process
1.13 3.89e-02 GO:0048869 cellular developmental process
1.11 4.07e-02 GO:0051234 establishment of localization
1.72 4.31e-02 GO:0030522 intracellular receptor mediated signaling pathway
1.49 4.58e-02 GO:0006417 regulation of translation
1.59 4.82e-02 GO:0051028 mRNA transport
1.35 4.84e-02 GO:0007411 axon guidance
1.28 4.94e-02 GO:0043068 positive regulation of programmed cell death
1.31 4.96e-02 GO:0040008 regulation of growth

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 1.73e-87 GO:0005622 intracellular
1.16 3.34e-85 GO:0044424 intracellular part
1.17 1.59e-68 GO:0043226 organelle
1.17 7.02e-68 GO:0043229 intracellular organelle
1.19 5.31e-64 GO:0043227 membrane-bounded organelle
1.19 8.59e-64 GO:0043231 intracellular membrane-bounded organelle
1.25 8.35e-53 GO:0005634 nucleus
1.17 4.61e-46 GO:0005737 cytoplasm
1.21 6.08e-35 GO:0044446 intracellular organelle part
1.37 1.07e-33 GO:0044428 nuclear part
1.20 6.33e-33 GO:0044422 organelle part
1.18 2.83e-29 GO:0044444 cytoplasmic part
1.36 4.08e-26 GO:0031981 nuclear lumen
1.42 1.01e-24 GO:0005654 nucleoplasm
1.31 1.27e-22 GO:0005829 cytosol
1.29 1.20e-20 GO:0070013 intracellular organelle lumen
1.04 1.37e-20 GO:0044464 cell part
1.04 1.60e-20 GO:0005623 cell
1.27 6.01e-19 GO:0043233 organelle lumen
1.27 7.89e-19 GO:0031974 membrane-enclosed lumen
1.48 8.04e-17 GO:0044451 nucleoplasm part
1.49 1.66e-13 GO:0005694 chromosome
1.20 2.01e-13 GO:0043234 protein complex
1.17 1.58e-11 GO:0032991 macromolecular complex
1.49 7.69e-11 GO:0044427 chromosomal part
1.19 8.59e-11 GO:0043228 non-membrane-bounded organelle
1.19 8.59e-11 GO:0043232 intracellular non-membrane-bounded organelle
1.23 1.43e-08 GO:0012505 endomembrane system
1.68 5.36e-08 GO:0031252 cell leading edge
1.18 6.90e-07 GO:0031090 organelle membrane
1.27 7.82e-07 GO:0005794 Golgi apparatus
1.32 1.26e-06 GO:0015630 microtubule cytoskeleton
2.87 1.56e-06 GO:0031519 PcG protein complex
2.13 3.78e-06 GO:0034708 methyltransferase complex
2.13 3.78e-06 GO:0035097 histone methyltransferase complex
1.43 5.90e-06 GO:0048471 perinuclear region of cytoplasm
1.33 1.00e-05 GO:0044431 Golgi apparatus part
1.49 2.30e-05 GO:0005667 transcription factor complex
1.57 2.92e-05 GO:0005819 spindle
1.86 3.03e-05 GO:0000790 nuclear chromatin
1.49 3.48e-05 GO:0005635 nuclear envelope
1.49 5.19e-05 GO:0000785 chromatin
1.41 6.03e-05 GO:0005815 microtubule organizing center
1.61 9.12e-05 GO:0031965 nuclear membrane
1.50 1.13e-04 GO:0000228 nuclear chromosome
1.55 1.68e-04 GO:0044454 nuclear chromosome part
1.21 2.20e-04 GO:0005783 endoplasmic reticulum
1.75 2.71e-04 GO:0016585 chromatin remodeling complex
1.33 2.80e-04 GO:0000139 Golgi membrane
1.17 1.30e-03 GO:0005856 cytoskeleton
1.42 4.15e-03 GO:0016604 nuclear body
1.77 4.34e-03 GO:0034399 nuclear periphery
1.23 5.54e-03 GO:0031975 envelope
1.23 9.02e-03 GO:0031967 organelle envelope
1.96 1.04e-02 GO:0008287 protein serine/threonine phosphatase complex
1.75 1.46e-02 GO:0000123 histone acetyltransferase complex
1.76 1.54e-02 GO:0016363 nuclear matrix
1.39 1.80e-02 GO:0005813 centrosome
1.64 1.95e-02 GO:0030027 lamellipodium
1.49 1.99e-02 GO:0000775 chromosome, centromeric region
1.49 2.44e-02 GO:0000151 ubiquitin ligase complex
1.27 2.97e-02 GO:0005768 endosome
1.32 4.52e-02 GO:0005874 microtubule
1.17 4.91e-02 GO:0044430 cytoskeletal part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 4.49e-62 GO:0005515 protein binding
1.11 2.13e-49 GO:0005488 binding
1.25 6.64e-16 GO:0000166 nucleotide binding
1.19 7.41e-14 GO:0003676 nucleic acid binding
1.22 3.11e-12 GO:0003677 DNA binding
1.25 6.01e-12 GO:0017076 purine nucleotide binding
1.25 8.77e-12 GO:0035639 purine ribonucleoside triphosphate binding
1.24 9.51e-12 GO:0032553 ribonucleotide binding
1.24 9.51e-12 GO:0032555 purine ribonucleotide binding
1.51 4.52e-11 GO:0019904 protein domain specific binding
1.33 1.37e-10 GO:0030528 transcription regulator activity
1.24 1.87e-10 GO:0016740 transferase activity
1.50 4.14e-10 GO:0004674 protein serine/threonine kinase activity
1.34 6.89e-10 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.37 1.23e-09 GO:0019899 enzyme binding
1.38 2.15e-09 GO:0043565 sequence-specific DNA binding
1.24 3.98e-09 GO:0030554 adenyl nucleotide binding
1.24 8.39e-09 GO:0032559 adenyl ribonucleotide binding
1.39 1.04e-08 GO:0004672 protein kinase activity
1.24 1.50e-08 GO:0005524 ATP binding
1.62 2.31e-08 GO:0019787 small conjugating protein ligase activity
1.11 2.87e-08 GO:0003824 catalytic activity
1.34 3.09e-08 GO:0016301 kinase activity
1.57 7.45e-08 GO:0016881 acid-amino acid ligase activity
1.34 1.44e-07 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.52 3.30e-07 GO:0008134 transcription factor binding
1.60 3.75e-07 GO:0004842 ubiquitin-protein ligase activity
1.45 4.82e-07 GO:0000988 protein binding transcription factor activity
1.45 4.82e-07 GO:0000989 transcription factor binding transcription factor activity
1.45 7.10e-07 GO:0003712 transcription cofactor activity
1.50 1.34e-06 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.26 3.23e-06 GO:0001071 nucleic acid binding transcription factor activity
1.26 3.23e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.46 6.17e-06 GO:0016563 transcription activator activity
1.58 6.29e-06 GO:0000975 regulatory region DNA binding
1.58 6.29e-06 GO:0001067 regulatory region nucleic acid binding
1.58 6.29e-06 GO:0044212 transcription regulatory region DNA binding
1.57 2.10e-05 GO:0010843 promoter binding
1.37 3.14e-05 GO:0016874 ligase activity
1.44 3.92e-05 GO:0016564 transcription repressor activity
1.34 1.77e-04 GO:0030695 GTPase regulator activity
1.33 2.76e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.90 8.23e-04 GO:0019902 phosphatase binding
1.55 8.41e-04 GO:0004721 phosphoprotein phosphatase activity
1.30 9.09e-04 GO:0008092 cytoskeletal protein binding
1.15 1.08e-03 GO:0008270 zinc ion binding
1.77 1.17e-03 GO:0031072 heat shock protein binding
1.91 3.01e-03 GO:0019903 protein phosphatase binding
1.53 5.19e-03 GO:0003714 transcription corepressor activity
1.41 7.18e-03 GO:0016791 phosphatase activity
1.25 7.95e-03 GO:0046983 protein dimerization activity
1.52 8.05e-03 GO:0008022 protein C-terminus binding
1.42 9.12e-03 GO:0003713 transcription coactivator activity
1.39 1.36e-02 GO:0003702 RNA polymerase II transcription factor activity
1.30 3.54e-02 GO:0008047 enzyme activator activity
1.96 4.00e-02 GO:0018024 histone-lysine N-methyltransferase activity
2.87 4.02e-02 GO:0015924 mannosyl-oligosaccharide mannosidase activity