Motif ID: TLX2.p2

Z-value: 1.486


Transcription factors associated with TLX2.p2:

Gene SymbolEntrez IDGene Name
TLX2 3196 T-cell leukemia homeobox 2



Activity profile for motif TLX2.p2.

activity profile for motif TLX2.p2


Sorted Z-values histogram for motif TLX2.p2

Sorted Z-values for motif TLX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_73810383 1.408 NM_001906
 CTRB1
CTRB2
chymotrypsinogen B1
chymotrypsinogen B2
chr12_+_55018925 1.386 NM_016584
 IL23A
interleukin 23, alpha subunit p19
chr11_-_83071084 1.205 NM_001142702
 DLG2
discs, large homolog 2 (Drosophila)
chr7_+_31693155 1.203 NM_001145123
NM_006658
 C7orf16

chromosome 7 open reading frame 16

chr9_+_94766379 1.165 FGD3
FYVE, RhoGEF and PH domain containing 3
chr1_-_155834357 1.082 NM_031282
 FCRL4
Fc receptor-like 4
chr6_-_41114905 1.068 NM_173561
 UNC5CL
unc-5 homolog C (C. elegans)-like
chr19_-_6671585 1.048 NM_000064
 C3
complement component 3
chr1_-_26553168 1.041 NM_001039775
 AIM1L
absent in melanoma 1-like
chr2_+_97696462 0.980 NM_001079
 ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr16_-_70763524 0.979 NM_031293
 PMFBP1
polyamine modulated factor 1 binding protein 1
chr1_-_25164061 0.953 NM_001031680
 RUNX3
runt-related transcription factor 3
chr6_+_167445284 0.938 NM_004367
 CCR6
chemokine (C-C motif) receptor 6
chr11_-_60880799 0.925 NM_001161452
 CYBASC3
cytochrome b, ascorbate dependent 3
chr10_-_97190885 0.895 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
 SORBS1




sorbin and SH3 domain containing 1




chr20_-_34707971 0.891 NM_032214
NM_175077
 SLA2

Src-like-adaptor 2

chr19_-_56612653 0.886 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
 SIGLEC10






sialic acid binding Ig-like lectin 10






chr1_+_159032551 0.877 NM_001033667
NM_002348
 LY9

lymphocyte antigen 9

chr7_-_99411573 0.864 NM_001185
 AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr8_-_27997306 0.833 NM_001010906
 C8orf80
chromosome 8 open reading frame 80

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.73 2.62e-02 GO:0050852 T cell receptor signaling pathway
2.49 1.83e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.39 4.00e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.12 1.35e-02 GO:0002757 immune response-activating signal transduction
2.07 2.43e-02 GO:0002764 immune response-regulating signaling pathway
2.05 4.01e-03 GO:0002253 activation of immune response
1.69 1.25e-02 GO:0050776 regulation of immune response
1.62 1.90e-04 GO:0006955 immune response
1.59 2.48e-03 GO:0002682 regulation of immune system process
1.51 3.77e-02 GO:0006915 apoptosis
1.50 4.29e-05 GO:0002376 immune system process
1.50 4.43e-02 GO:0012501 programmed cell death
1.39 1.93e-02 GO:0009893 positive regulation of metabolic process
1.27 2.48e-03 GO:0048518 positive regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
5.32 1.33e-02 GO:0042613 MHC class II protein complex
2.62 4.44e-02 GO:0016459 myosin complex
1.69 4.98e-02 GO:0015629 actin cytoskeleton
1.27 3.91e-03 GO:0044459 plasma membrane part
1.25 2.13e-02 GO:0005829 cytosol

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.12 8.64e-03 GO:0005515 protein binding