Motif ID: ZFP161.p2

Z-value: 1.813


Transcription factors associated with ZFP161.p2:

Gene SymbolEntrez IDGene Name
ZFP161 7541 zinc finger protein 161 homolog (mouse)



Activity profile for motif ZFP161.p2.

activity profile for motif ZFP161.p2


Sorted Z-values histogram for motif ZFP161.p2

Sorted Z-values for motif ZFP161.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZFP161.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_181237210 2.999 NM_016559
PEX5L
peroxisomal biogenesis factor 5-like
chr13_-_43259032 2.364 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr15_-_61680003 1.775 LOC100130855
hypothetical LOC100130855
chr14_+_73073570 1.650 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr10_+_122206455 1.621 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr4_+_19864332 1.611 NM_004787
SLIT2
slit homolog 2 (Drosophila)
chr2_-_233501069 1.606 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr22_-_30072329 1.600 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr22_-_39964001 1.575 CHADL
chondroadherin-like
chr2_+_207016525 1.517 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr20_+_20296744 1.513 NM_002196
INSM1
insulinoma-associated 1
chr22_-_37598160 1.478 CBX6
chromobox homolog 6
chr10_+_105243724 1.464 NM_004210
NEURL
neuralized homolog (Drosophila)
chr15_+_57517564 1.460 NM_152450
FAM81A
family with sequence similarity 81, member A
chr3_+_152286138 1.438 MED12L
mediator complex subunit 12-like
chr18_+_75825563 1.438 NM_001136180
HSBP1L1
heat shock factor binding protein 1-like 1
chr9_-_34579679 1.407 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr11_+_66381077 1.395 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr22_-_37598115 1.386 CBX6
chromobox homolog 6
chr10_+_80672842 1.328 ZMIZ1
zinc finger, MIZ-type containing 1
chr22_-_37598176 1.312 NM_014292
CBX6
chromobox homolog 6
chr8_+_120289735 1.311 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr17_-_19711580 1.300 NM_001142610
NM_014683
ULK2

unc-51-like kinase 2 (C. elegans)

chr10_+_105027431 1.291 INA
internexin neuronal intermediate filament protein, alpha
chr18_-_29412148 1.284


chr14_-_73106243 1.272


chr22_-_30072217 1.260 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr10_-_126128539 1.258 NM_001146340
NKX1-2
NK1 homeobox 2
chr16_+_53915971 1.256 NM_024335
IRX6
iroquois homeobox 6
chr13_-_31900218 1.252 NM_001079691
NM_052818
N4BP2L1

NEDD4 binding protein 2-like 1

chr2_+_149895274 1.227 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr2_+_71547325 1.219 NM_001130455
NM_001130982
NM_001130983
NM_001130984
NM_001130985
NM_001130986
NM_001130987
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr11_-_133786935 1.191 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr8_-_125809831 1.171 NM_014751
MTSS1
metastasis suppressor 1
chr11_+_66547391 1.146 NM_177963
SYT12
synaptotagmin XII
chr2_-_39040981 1.133 LOC375196
hypothetical LOC375196
chr20_-_56523251 1.120 NM_153360
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr11_+_128751044 1.113 NM_003658
BARX2
BARX homeobox 2
chr11_-_60819110 1.089 VWCE
von Willebrand factor C and EGF domains
chr21_+_32167175 1.086 NM_014586
HUNK
hormonally up-regulated Neu-associated kinase
chr5_-_146869613 1.084 DPYSL3
dihydropyrimidinase-like 3
chr14_+_103674812 1.081 NM_015656
KIF26A
kinesin family member 26A
chr20_-_9767406 1.080 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr18_-_44189625 1.078 ZBTB7C
zinc finger and BTB domain containing 7C
chr9_+_115957537 1.051 COL27A1
collagen, type XXVII, alpha 1
chr8_+_104582151 1.044 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr10_+_115793795 1.037 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr10_-_88720908 1.028 LOC100133190
hypothetical LOC100133190
chr11_-_407324 1.028 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr4_+_109072120 1.023 NM_183075
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr16_+_55180767 1.009 NM_005954
MT3
metallothionein 3
chr15_-_50375143 1.001 NM_018728
MYO5C
myosin VC
chr1_+_234372454 1.000 NM_003272
GPR137B
G protein-coupled receptor 137B
chr3_-_55496370 0.996 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr14_+_73128162 0.985 NM_152331
ACOT4
acyl-CoA thioesterase 4
chr17_+_56832255 0.972 TBX2
T-box 2
chr1_+_229829143 0.968 NM_001012957
NM_001012958
NM_001012959
NM_001164537
NM_001164538
NM_001164539
NM_001164540
NM_001164541
NM_001164542
NM_001164544
NM_001164545
NM_001164546
NM_001164547
NM_001164548
NM_001164549
NM_001164550
NM_001164551
NM_001164552
NM_001164553
NM_001164554
NM_001164555
NM_001164556
NM_018662
DISC1






















disrupted in schizophrenia 1






















chr2_-_40532651 0.967 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr5_-_146869811 0.965 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr10_+_124210980 0.945 NM_002775
HTRA1
HtrA serine peptidase 1
chr14_+_73105618 0.926 ACOT2
acyl-CoA thioesterase 2
chr10_-_105604942 0.925 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr16_-_71639670 0.923 NM_006885
ZFHX3
zinc finger homeobox 3
chr10_-_30065760 0.922 SVIL
supervillin
chr7_+_78920846 0.916 LOC100505881
hypothetical LOC100505881
chr2_+_29191711 0.914 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr15_-_69194854 0.913 NM_001102658
CT62
cancer/testis antigen 62
chr3_-_185025989 0.911 NM_024871
MAP6D1
MAP6 domain containing 1
chr9_+_128416542 0.910 NM_001174146
NM_001174147
NM_002316
LMX1B


LIM homeobox transcription factor 1, beta


chr1_-_48235148 0.907 NM_001194986
LOC388630
UPF0632 protein A
chr11_-_1549719 0.888 NM_004420
DUSP8
dual specificity phosphatase 8
chr7_-_27180398 0.881 NM_018951
HOXA10
homeobox A10
chr12_+_93066370 0.880 NM_005761
PLXNC1
plexin C1
chr12_-_24606616 0.879 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr3_+_144321286 0.878 NM_004267
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr17_-_19589363 0.873 NM_001135168
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr17_+_8865547 0.871 NM_004822
NTN1
netrin 1
chr10_+_60606352 0.871 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr2_-_213111525 0.864 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr13_-_71338144 0.860 DACH1
dachshund homolog 1 (Drosophila)
chr1_+_151917674 0.858 NM_000906
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr18_-_21184824 0.856


chr4_-_5945596 0.853 NM_001014809
CRMP1
collapsin response mediator protein 1
chr10_-_28074752 0.849 NM_173576
MKX
mohawk homeobox
chr17_+_56831951 0.849 NM_005994
TBX2
T-box 2
chr4_-_110443247 0.842 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr3_-_129023850 0.842 NM_007283
MGLL
monoglyceride lipase
chr6_+_124166767 0.838 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr2_-_47650973 0.829 NM_022055
KCNK12
potassium channel, subfamily K, member 12
chr10_-_131652007 0.828 NM_001005463
EBF3
early B-cell factor 3
chr14_-_77034853 0.823 NM_182509
NM_199296
ISM2

isthmin 2 homolog (zebrafish)

chr5_-_101659864 0.818 NM_180991
SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr17_+_4348877 0.818 NM_001124758
SPNS2
spinster homolog 2 (Drosophila)
chr18_-_7107757 0.814 NM_005559
LAMA1
laminin, alpha 1
chr7_-_27149750 0.814 NM_019102
HOXA5
homeobox A5
chr4_+_76077229 0.811 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr1_+_35811557 0.808 NM_178548
TFAP2E
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr6_+_37245860 0.805 NM_002648
PIM1
pim-1 oncogene
chr9_-_21984329 0.798 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr2_+_64534774 0.796 NM_014181
HSPC159
galectin-related protein
chr10_-_82106479 0.795 NM_138812
DYDC1
DPY30 domain containing 1
chr9_-_111300350 0.794 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr5_-_168660293 0.794 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr18_+_29412538 0.792 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr12_+_56406296 0.789 LOC100130776
hypothetical LOC100130776
chr9_-_139214962 0.788 NM_001128228
TPRN
taperin
chr18_+_42167904 0.783 RNF165
ring finger protein 165
chr20_+_35583020 0.778 NM_005386
NM_181689
NNAT

neuronatin

chr22_-_36153449 0.773 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr10_+_82106537 0.773 NM_032372
DYDC2
DPY30 domain containing 2
chr3_-_55496607 0.771 WNT5A
wingless-type MMTV integration site family, member 5A
chr3_+_11171213 0.771 NM_001098212
HRH1
histamine receptor H1
chr12_-_97812633 0.767 ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr3_-_129689394 0.761 NM_001145662
GATA2
GATA binding protein 2
chr7_-_45927263 0.758 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr9_-_71476917 0.756 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr13_-_32822759 0.752 STARD13
StAR-related lipid transfer (START) domain containing 13
chr8_-_125809559 0.750 MTSS1
metastasis suppressor 1
chrX_-_19815526 0.746 SH3KBP1
SH3-domain kinase binding protein 1
chr9_-_4289574 0.745 GLIS3
GLIS family zinc finger 3
chr4_+_72271218 0.745 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr7_-_27136876 0.742 NM_002141
HOXA4
homeobox A4
chr1_-_215377718 0.739 NM_001134285
ESRRG
estrogen-related receptor gamma
chr12_-_43731148 0.734 NM_001004329
DBX2
developing brain homeobox 2
chr10_-_60606195 0.731


chr5_-_83716346 0.719 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr3_-_129024665 0.715 NM_001003794
MGLL
monoglyceride lipase
chr9_-_139316523 0.710 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr7_-_139987044 0.709 DENND2A
DENN/MADD domain containing 2A
chr11_-_60819273 0.703 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr7_-_127788893 0.702 NM_001114726
NM_001174164
PRRT4

proline-rich transmembrane protein 4

chr19_+_876984 0.699 NM_005224
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr9_-_39278061 0.698 NM_033655
LOC441402
CNTNAP3
contactin associated protein-like 3 pseudogene
contactin associated protein-like 3
chr14_+_69021149 0.696 NM_001161498
UPF0639
UPF0639 protein
chr8_-_89408832 0.696 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr15_+_30109982 0.695 NM_000746
NM_001190455
CHRNA7

cholinergic receptor, nicotinic, alpha 7

chr18_+_13208777 0.694 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr1_+_4614528 0.694 AJAP1
adherens junctions associated protein 1
chr2_+_26924466 0.693 NM_020134
DPYSL5
dihydropyrimidinase-like 5
chr9_-_21984414 0.692 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr15_+_97462675 0.690 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr16_+_84204424 0.689 NM_014615
KIAA0182
KIAA0182
chr21_-_27261276 0.686 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr14_-_62581656 0.684 NM_139318
NM_172375
KCNH5

potassium voltage-gated channel, subfamily H (eag-related), member 5

chr11_-_30564338 0.678 NM_001145399
MPPED2
metallophosphoesterase domain containing 2
chr11_-_110088330 0.673 NM_020809
ARHGAP20
Rho GTPase activating protein 20
chr18_+_42168180 0.672 NM_152470
C18orf23
RNF165
chromosome 18 open reading frame 23
ring finger protein 165
chr15_+_31390454 0.670 NM_001036
RYR3
ryanodine receptor 3
chr4_+_107036042 0.669 NM_001033047
NM_001184690
NM_001184691
NM_001184692
NM_001184693
NPNT




nephronectin




chr2_-_236740710 0.667


chr17_+_2187545 0.666 NM_014853
NM_001098509
SGSM2

small G protein signaling modulator 2

chr14_+_41146513 0.666 NM_152447
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr1_+_60053050 0.663 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr22_+_47263919 0.661 NM_001082967
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr2_-_139254273 0.660 NM_007226
NXPH2
neurexophilin 2
chr9_+_17568952 0.660 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr21_+_33364420 0.659 OLIG1
oligodendrocyte transcription factor 1
chr11_+_12987455 0.656 NM_001080521
RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr2_+_104837004 0.654


chr8_+_76059262 0.653 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr11_+_110916629 0.651 LAYN
layilin
chr5_+_75734759 0.651 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr7_+_45580704 0.643 ADCY1
adenylate cyclase 1 (brain)
chr15_+_78858763 0.642 NM_018689
KIAA1199
KIAA1199
chr6_+_41714171 0.638 NM_005586
MDFI
MyoD family inhibitor
chr20_-_61933012 0.638 ZBTB46
zinc finger and BTB domain containing 46
chr5_-_58370693 0.637 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr1_+_208568811 0.635 NM_001170587
NM_001170588
NM_018194
HHAT


hedgehog acyltransferase


chr9_-_21984379 0.633 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr5_-_132976094 0.633 FSTL4
follistatin-like 4
chr2_-_86418143 0.631 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr5_-_132976121 0.628 NM_015082
FSTL4
follistatin-like 4
chr6_+_17210467 0.628 NM_001190766
FLJ23152
hypothetical protein LOC401236
chr2_+_120820140 0.628 NM_002193
INHBB
inhibin, beta B
chr1_-_6468108 0.627 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr7_+_45580606 0.627 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr5_+_135392482 0.626 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr14_+_70178126 0.626 NM_015351
TTC9
tetratricopeptide repeat domain 9
chr14_+_73105515 0.621 NM_006821
ACOT2
acyl-CoA thioesterase 2
chr1_-_6468600 0.619 NM_001042665
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr5_+_135392624 0.617 TGFBI
transforming growth factor, beta-induced, 68kDa
chr19_+_7874820 0.616 MAP2K7
mitogen-activated protein kinase kinase 7
chr13_+_24152548 0.615 NM_001185085
NM_001676
ATP12A

ATPase, H+/K+ transporting, nongastric, alpha polypeptide

chr8_+_65656164 0.613 BHLHE22
basic helix-loop-helix family, member e22
chr22_-_49062461 0.610 PLXNB2
plexin B2
chr11_+_57191887 0.610 ZDHHC5
zinc finger, DHHC-type containing 5
chr8_+_121892719 0.606


chr2_+_137239583 0.602 THSD7B
thrombospondin, type I, domain containing 7B
chr20_+_13150417 0.602 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr10_+_90629880 0.599 NM_020799
STAMBPL1
STAM binding protein-like 1
chr3_+_39826032 0.599 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr14_+_23590939 0.599 NM_138360
LRRC16B
leucine rich repeat containing 16B
chr17_-_24918052 0.598 NM_198147
ABHD15
abhydrolase domain containing 15
chr3_-_171786468 0.597 NM_020949
SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr10_+_104169560 0.596 NM_024326
FBXL15
F-box and leucine-rich repeat protein 15
chr7_+_87401368 0.595 NM_004194
NM_016351
NM_021721
NM_021722
NM_021723
ADAM22




ADAM metallopeptidase domain 22




chr9_+_101623957 0.594 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr5_-_134899537 0.594 NM_006161
NEUROG1
neurogenin 1
chr18_-_19496590 0.593 NM_173505
ANKRD29
ankyrin repeat domain 29
chr5_-_16670085 0.590 NM_001034850
FAM134B
family with sequence similarity 134, member B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 1.32e-24 GO:0007275 multicellular organismal development
1.63 1.91e-24 GO:0007399 nervous system development
1.35 5.45e-23 GO:0032502 developmental process
1.38 1.83e-18 GO:0048731 system development
1.33 2.48e-16 GO:0048856 anatomical structure development
1.66 2.97e-15 GO:0022008 neurogenesis
1.41 9.03e-15 GO:0030154 cell differentiation
1.67 1.44e-14 GO:0048699 generation of neurons
1.64 1.47e-14 GO:0048468 cell development
1.40 6.06e-14 GO:0048869 cellular developmental process
1.48 1.02e-13 GO:0009653 anatomical structure morphogenesis
1.18 1.08e-13 GO:0050794 regulation of cellular process
1.11 1.82e-13 GO:0009987 cellular process
1.84 4.09e-13 GO:0007417 central nervous system development
1.16 8.93e-13 GO:0065007 biological regulation
1.82 3.81e-12 GO:0000904 cell morphogenesis involved in differentiation
1.16 4.17e-12 GO:0050789 regulation of biological process
1.68 1.10e-11 GO:0030182 neuron differentiation
1.78 8.16e-11 GO:0031175 neuron projection development
1.84 2.39e-10 GO:0007409 axonogenesis
1.71 2.51e-10 GO:0048666 neuron development
1.52 6.18e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.68 9.95e-10 GO:0009887 organ morphogenesis
1.80 1.02e-09 GO:0048667 cell morphogenesis involved in neuron differentiation
1.78 2.04e-09 GO:0048812 neuron projection morphogenesis
1.65 2.12e-09 GO:0032989 cellular component morphogenesis
1.61 2.45e-09 GO:0009790 embryo development
1.66 2.91e-09 GO:0000902 cell morphogenesis
1.85 4.17e-09 GO:0007420 brain development
1.62 8.38e-09 GO:0030030 cell projection organization
1.34 1.16e-08 GO:0048513 organ development
1.70 1.18e-08 GO:0032990 cell part morphogenesis
1.87 1.87e-08 GO:0007411 axon guidance
1.69 2.43e-08 GO:0048858 cell projection morphogenesis
1.83 6.39e-08 GO:0007389 pattern specification process
1.35 1.53e-07 GO:0023051 regulation of signaling
1.21 4.37e-07 GO:0023052 signaling
1.57 9.72e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.54 1.74e-06 GO:0051254 positive regulation of RNA metabolic process
1.79 2.04e-06 GO:0060284 regulation of cell development
1.53 2.28e-06 GO:0010628 positive regulation of gene expression
1.26 3.66e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.35 3.72e-06 GO:0009966 regulation of signal transduction
1.52 4.00e-06 GO:0045595 regulation of cell differentiation
1.27 4.02e-06 GO:0051252 regulation of RNA metabolic process
1.24 4.46e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 4.92e-06 GO:0006355 regulation of transcription, DNA-dependent
1.48 6.76e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 7.25e-06 GO:0050793 regulation of developmental process
1.16 9.43e-06 GO:0032501 multicellular organismal process
1.24 9.91e-06 GO:0010468 regulation of gene expression
1.61 1.07e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.44 1.59e-05 GO:0006351 transcription, DNA-dependent
1.23 1.62e-05 GO:0031326 regulation of cellular biosynthetic process
1.46 1.93e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.24 2.02e-05 GO:0071842 cellular component organization at cellular level
1.13 2.08e-05 GO:0044237 cellular metabolic process
1.68 2.34e-05 GO:0043009 chordate embryonic development
1.67 2.37e-05 GO:0009792 embryo development ending in birth or egg hatching
1.23 2.78e-05 GO:0009889 regulation of biosynthetic process
1.24 3.06e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.59 3.38e-05 GO:0072358 cardiovascular system development
1.59 3.38e-05 GO:0072359 circulatory system development
1.64 3.54e-05 GO:0009968 negative regulation of signal transduction
1.20 4.75e-05 GO:0007165 signal transduction
1.84 5.03e-05 GO:0003002 regionalization
1.55 5.32e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.22 6.44e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.45 6.86e-05 GO:2000026 regulation of multicellular organismal development
1.19 7.66e-05 GO:0016043 cellular component organization
1.60 7.98e-05 GO:0023057 negative regulation of signaling
1.59 9.36e-05 GO:0010648 negative regulation of cell communication
1.45 1.05e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.19 1.10e-04 GO:0031323 regulation of cellular metabolic process
1.53 1.24e-04 GO:0051253 negative regulation of RNA metabolic process
1.79 1.30e-04 GO:0050767 regulation of neurogenesis
1.41 1.41e-04 GO:0040011 locomotion
1.70 1.67e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.21 1.94e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.27 2.89e-04 GO:0007166 cell surface receptor linked signaling pathway
1.18 3.08e-04 GO:0080090 regulation of primary metabolic process
1.40 3.54e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.32 3.83e-04 GO:0051239 regulation of multicellular organismal process
1.48 4.24e-04 GO:0010629 negative regulation of gene expression
2.05 5.13e-04 GO:0030111 regulation of Wnt receptor signaling pathway
1.24 5.75e-04 GO:0048523 negative regulation of cellular process
1.64 6.21e-04 GO:0045597 positive regulation of cell differentiation
1.16 7.24e-04 GO:0051716 cellular response to stimulus
1.22 7.62e-04 GO:0048522 positive regulation of cellular process
1.22 7.86e-04 GO:0048519 negative regulation of biological process
1.15 8.32e-04 GO:0044260 cellular macromolecule metabolic process
1.39 8.83e-04 GO:0009891 positive regulation of biosynthetic process
1.82 9.29e-04 GO:0045664 regulation of neuron differentiation
1.69 9.35e-04 GO:0035295 tube development
1.17 1.03e-03 GO:0071840 cellular component organization or biogenesis
1.18 1.24e-03 GO:0060255 regulation of macromolecule metabolic process
1.44 1.28e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.41 1.34e-03 GO:0006468 protein phosphorylation
1.35 1.39e-03 GO:0032774 RNA biosynthetic process
2.17 1.45e-03 GO:0003007 heart morphogenesis
1.50 1.51e-03 GO:0048585 negative regulation of response to stimulus
1.73 1.61e-03 GO:0007507 heart development
1.25 1.68e-03 GO:0006464 protein modification process
1.45 1.72e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 1.82e-03 GO:0006793 phosphorus metabolic process
1.34 1.82e-03 GO:0006796 phosphate metabolic process
1.67 1.93e-03 GO:0051960 regulation of nervous system development
1.44 2.30e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.24 2.38e-03 GO:0043412 macromolecule modification
1.57 2.63e-03 GO:0048598 embryonic morphogenesis
1.33 3.34e-03 GO:0010646 regulation of cell communication
1.48 3.67e-03 GO:0006935 chemotaxis
1.48 3.67e-03 GO:0042330 taxis
1.42 3.86e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.43 3.92e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.37 4.33e-03 GO:0016310 phosphorylation
1.15 4.68e-03 GO:0019222 regulation of metabolic process
1.40 5.56e-03 GO:0009890 negative regulation of biosynthetic process
1.91 6.00e-03 GO:0050678 regulation of epithelial cell proliferation
1.84 6.93e-03 GO:0009952 anterior/posterior pattern formation
1.53 6.94e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.59 7.60e-03 GO:0001501 skeletal system development
1.69 8.56e-03 GO:0048568 embryonic organ development
1.23 8.60e-03 GO:0048583 regulation of response to stimulus
1.40 8.90e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.18 1.01e-02 GO:0048518 positive regulation of biological process
1.10 1.03e-02 GO:0008152 metabolic process
1.10 1.31e-02 GO:0044238 primary metabolic process
1.90 1.90e-02 GO:0048705 skeletal system morphogenesis
1.90 2.24e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.69 2.38e-02 GO:0043193 positive regulation of gene-specific transcription
2.13 2.57e-02 GO:0060485 mesenchyme development
1.44 2.59e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.99 2.63e-02 GO:0010720 positive regulation of cell development
3.64 2.83e-02 GO:0017145 stem cell division
1.89 2.87e-02 GO:0022604 regulation of cell morphogenesis
2.58 3.60e-02 GO:0001570 vasculogenesis
2.12 4.04e-02 GO:0030178 negative regulation of Wnt receptor signaling pathway
1.30 4.43e-02 GO:0009605 response to external stimulus
1.76 4.55e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
2.38 4.86e-02 GO:0045667 regulation of osteoblast differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 1.11e-07 GO:0005634 nucleus
1.07 3.10e-06 GO:0044424 intracellular part
1.07 1.01e-05 GO:0005622 intracellular
1.09 1.68e-05 GO:0043227 membrane-bounded organelle
1.09 1.78e-05 GO:0043231 intracellular membrane-bounded organelle
1.56 1.46e-04 GO:0043005 neuron projection
1.07 4.33e-04 GO:0043226 organelle
1.07 5.17e-04 GO:0043229 intracellular organelle
1.52 7.43e-04 GO:0045202 synapse
1.19 6.81e-03 GO:0044459 plasma membrane part
1.93 1.47e-02 GO:0005925 focal adhesion
1.69 1.52e-02 GO:0043025 neuronal cell body
1.35 2.66e-02 GO:0030054 cell junction
1.07 3.46e-02 GO:0005737 cytoplasm
1.64 3.76e-02 GO:0044297 cell body
1.70 4.18e-02 GO:0005912 adherens junction
1.43 4.99e-02 GO:0031012 extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.60 2.59e-15 GO:0030528 transcription regulator activity
1.73 7.66e-15 GO:0043565 sequence-specific DNA binding
1.59 1.44e-14 GO:0001071 nucleic acid binding transcription factor activity
1.59 1.44e-14 GO:0003700 sequence-specific DNA binding transcription factor activity
1.09 1.35e-11 GO:0005488 binding
1.27 8.02e-08 GO:0003677 DNA binding
1.12 5.99e-07 GO:0005515 protein binding
1.55 1.11e-04 GO:0019904 protein domain specific binding
1.17 7.67e-04 GO:0003676 nucleic acid binding
2.23 9.70e-04 GO:0019199 transmembrane receptor protein kinase activity
1.58 1.65e-03 GO:0016563 transcription activator activity
1.51 2.60e-02 GO:0016564 transcription repressor activity
1.33 3.26e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.73 4.38e-02 GO:0003714 transcription corepressor activity